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1 SLC also induced calcium mobilization specifically in ma
2 SLC and Epstein-Barr virus-induced molecule 1 ligand che
3 SLC elicited a substantial infiltration of DCs and T cel
4 SLC injection led to significant increases in CD4 and CD
5 SLC is a highly efficacious chemoattractant for lymphocy
6 SLC is likely to play an important role in regulating th
7 SLC was a potent in vitro chemoattractant for cultured,
8 SLC-mediated antitumor responses were lymphocyte depende
9 SLCs interact with several important drugs, and a quarte
10 CC chemokine CCL21, also known as Exodus-2, SLC, 6Ckine, and TCA4 induces both the adhesion and migr
11 emokines, Exodus-1/LARC/MIP-3alpha, Exodus-2/SLC/6Ckine/TCA4, and Exodus-3/CKbeta11/MIP-3beta, were f
12 Its ligands, CCL-19 (MIP-3beta) and CCL-21 (SLC), play an important role in the migration of these c
15 ty of circulating lymphocytes respond to 6CK/SLC and MIP-3beta in large part through their common rec
17 isolated by us and others as Exodus-2/6Ckine/SLC/TCA4) is highly potent and highly specific for stimu
18 olar concentrations of MCH strongly activate SLC-1-related pathways through G(alpha)i and/or G(alpha)
20 sity increased the probability of evoking an SLC and decreased mean SLC latencies while increasing th
21 single functional ELC gene, leaving only an SLC gene that is expressed in lymphatic endothelium and
22 es confirmed increased IL-7, SDF-1alpha, and SLC gene expression in MHC class II+ CD45- epithelial ce
23 polymorphisms in genes encoding for ABC and SLC transporters may have a significant impact on the ph
27 a was not necessary for induction of BLC and SLC in inflamed tissues, whereas, in contrast, tumor nec
28 ross-kissing interactions (SL-C to SL-D' and SLC' to SL-D) and stack in an end-to-end manner (SL-C to
31 art from their latencies, SLC kinematics and SLC field potential parameters were intensity independen
36 The levels of IL-7, SDF-1alpha, TECK, and SLC mRNA inversely correlated with the kinetics of regen
37 at expression of IL-7, SDF-1alpha, TECK, and SLC mRNA is induced in the thymic stroma during T cell d
42 tudies, we examined the consequences of anti-SLC Ab treatment during Ag priming on T cell function in
46 he suppressor of long chain base auxotrophy (SLC, strain 7R4) showed a heat-sensitive phenotype that
47 the potential to sequester latent TGF-beta (SLC) to the cell surface where TGF-beta activation could
50 n of the Cucumber mosaic virus (CMV) and BMV SLCs indicates that the requirements in the BMV SLC are
51 at the plt defect is due to the loss of both SLC and EBI-1 ligand chemokine (ELC) expression in secon
52 Neutrophils roll, but are not arrested by SLC, whereas they respond to immobilized IL-8 with rapid
54 virus (BMV), a stem-loop structure named C (SLC) is present within the tRNA-like region and is requi
55 n this region, a stem-loop structure, called SLC, is necessary and sufficient for the binding of the
58 porter Bor1, a member of the solute carrier (SLC) 4 transporter family with homology to the human bic
59 ansport studies suggest that solute carrier (SLC) and ATP binding cassette (ABC) multispecific "drug"
60 ncluding those controlled by solute carrier (SLC) and ATP-binding cassette (ABC) transporters and dru
61 s a member of a gene family, solute carrier (SLC) family 26, that encodes anion transporters and rela
63 ma membrane transporter, the solute carrier (SLC) human multidrug and toxin extrusion protein 1 (hMAT
65 h more than 400 members, the solute carrier (SLC) membrane transport proteins are the largest family
69 2 (SLC22A7), a member of the solute carrier (SLC) superfamily, was a facilitative transporter for cGM
71 OATP2B1, a member of the solute carrier (SLC) transporter family, is an important mechanism of su
72 drug molecules, which hijack solute carrier (SLC) transporters for active transport into the body.
73 There are over 420 human solute carrier (SLC) transporters from 65 families that are expressed ub
76 lls is suppressed in CCL19 (ELC)- and CCL21 (SLC)-deficient paucity of lymph node T cells mice, but n
79 ultures of steroidogenic small luteal cells (SLCs), LH, and forskolin stimulated phosphorylation of D
85 s secondary lymphoid tissue chemoattractant (SLC) and macrophage inflammatory protein (MIP)-3beta, im
86 in response to the lymphoid homing chemokine SLC/CCL21: CD4(-) Valpha14i-negative NKT cells that were
88 amma (Mig) and secondary lymphoid chemokine (SLC) gene expression within allografts and spleens respe
89 votal role for secondary lymphoid chemokine (SLC) in directing dendritic cell trafficking from periph
90 and 21 (CCL21)/secondary lymphoid chemokine (SLC), a ligand for CC chemokine receptor 7 (CCR7), has b
93 iency of secondary lymphoid organ chemokine (SLC), a CC chemokine that chemoattracts both dendritic c
94 acks the secondary lymphoid organ chemokine (SLC)-ser gene and has disrupted trafficking of T cells a
95 luminal secondary lymphoid tissue chemokine (SLC) (6Ckine, Exodus-2, thymus-derived chemotactic agent
96 rt that secondary lymphoid-tissue chemokine (SLC) (also known as 6Ckine, Exodus-2, and thymus-derived
98 okines (secondary lymphoid tissue chemokine (SLC) and EBV-induced molecule 1 ligand chemokine (ELC))
100 express secondary lymphoid tissue chemokine (SLC) into growing B16 melanoma could result in a substan
104 actant, secondary lymphoid tissue chemokine (SLC), by T zone stromal cells is found to be markedly de
105 ngkine, secondary lymphoid-tissue chemokine (SLC), EBI1-ligand chemokine (ELC), fractalkine, macropha
106 tabase, secondary lymphoid-tissue chemokine (SLC), is expressed in the high endothelial venules of ly
107 ncludes secondary lymphoid tissue chemokine (SLC), which promotes the colocalization of naive, nonpol
109 DCs to secondary lymphoid tissue chemokine (SLC)/CC chemokine ligand 21 (CCL21) were significantly l
110 s CCR7 (secondary lymphoid-tissue chemokine (SLC)/CC ligand (CCL)21), CXCR4 (stromal cell-derived fac
112 vement, secondary lymphoid tissue chemokine (SLC, CCL21) and Epstein-Barr virus-induced molecule 1 li
118 We also introduce Self-Label Clustering (SLC), an unsupervised clustering method relying on featu
119 xt of the entire tRNA-like element, both CMV SLC-like motifs are recognized by the BMV replicase.
121 Ps) composed of sequences of low complexity (SLC) have been shown to serve a variety of important cel
122 eplicated associations of the amine compound SLC (solute-carrier) transporters gene set with the lear
123 iseases using a "sneaking ligand construct" (SLC) selectively inhibiting NF-kappaB in the activated e
124 is paper, a sampling-based learning control (SLC) method is used to guide the design of control field
125 e Guyot (SG), single spur pruned low cordon (SLC) and single spur pruned high wire cordon (HSLC) as t
127 that increasing stimulus intensity decreased SLC latencies while increasing their precision, which wa
130 ts and associated challenges toward drugging SLCs, as well as highlight opportunities for future drug
135 tal structures of prokaryotic and eukaryotic SLC transporters indicating the location of both (or one
136 c. injection of lysate-pulsed DCs expressing SLC promoted the migration of T cells to the immunizatio
138 diverse heavy chains are paired with a fixed SLC were expressed in mammalian, Escherichia coli, and p
139 A CP was found to have higher affinities for SLC and the B box compared with those of wild-type CP an
140 hemokine receptor 7 (CCR7), the receptor for SLC and for macrophage inflammatory protein (MIP)-3beta
142 These results indicate an important role for SLC during sensitization for CHS and suggest a strategy
145 four of eight BALB/c mice and three of four SLC:ddY mice expressed one or more opacity (Opa) protein
146 r, splenic and lymph node-derived cells from SLC-treated tumor-bearing mice secreted significantly mo
147 ubtraction of field potential latencies from SLC latencies revealed a fixed time delay between the tw
148 s tumor, lymph node-derived lymphocytes from SLC-treated tumor-bearing mice demonstrated enhanced cyt
149 rradiated autologous tumor, splenocytes from SLC-treated mice secreted significantly more IFN-gamma a
150 natural ligand of a particular orphan GPCR (SLC-1) that is sequentially homologous to the somatostat
151 While the majority of CMV isolates have SLC-like elements similar to that of Fny-CMV, a second g
152 dministration of amplicons encoding SLC (HSV-SLC) into s.c. tumors established previously resulted in
153 mbined transduction of either tumor with HSV-SLC and HSV-CD40L resulted in a more enhanced antitumor
155 sensing and signalling hypothesis identifies SLC and ABC transporter-mediated communication between o
159 P-3beta signaling, and occurs efficiently in SLC(low/-) HEV segments in wild-type mice, and in the SL
161 response to albuterol in Latinos, notably in SLC genes that include membrane transport proteins invol
163 d nonmucoid pharyngeal isolates recovered in SLC from 1984 to 1999 were studied by sequencing the emm
164 that an ADME gene-centered network-including SLC and ABC "drug" transporters, "drug" metabolizing enz
169 ately derive from undifferentiated stem LCs (SLCs), which are postulated to be present in testes befo
172 ability of evoking an SLC and decreased mean SLC latencies while increasing their precision; subtract
173 une strategy, we show that amplicon-mediated SLC and CD40L delivery may mimic lymph node conditions n
174 re we describe recent approaches to modulate SLC transporter function, with an emphasis on the use of
176 preferentially bind to an RNA element named SLC that contains the core promoter for genomic minus-st
180 rom human PDAC cells, oral administration of SLC-0111 and injection of gemcitabine increased intratum
181 ically modified mice, oral administration of SLC-0111 and injection of gemcitabine reduced numbers of
184 sensing and signaling network" consisting of SLC and ABC transporters, as well as DMEs and regulatory
186 cells, suggesting that the dysregulation of SLC/ELC- expression alone in Ltbr-/- thymi can be suffic
189 trong rationale for additional evaluation of SLC in regulation of tumor immunity and its use in lung
190 a strong rationale for further evaluation of SLC in tumor immunity and its use in cancer immunotherap
191 phoid organs, is important for expression of SLC and BLC in secondary lymphoid organs during developm
193 due to a genetic defect in the expression of SLC and that SLC mediates the entry of naive T cells and
199 mise in this regard however, practicality of SLC isolation/transplantation impede clinical translatio
201 behavior of mRNA levels for a wide range of SLC and ABC transporters in the rodent kidney throughout
203 , bile) via "matching" or homologous sets of SLC (e.g., SLC21, SLC22, SLC47) and ABC transporters.
204 ermined the high-resolution NMR structure of SLC, which demonstrated that a 5'-AUA-3' triloop region
207 st in elucidating the physiological roles of SLCs as well as growing recognition of their therapeutic
209 The time is right for a systematic attack on SLC structure, specificity, and function, taking into ac
211 Furthermore, RIP-mOVA transgenic mice on SLC/ELC deficient background (plt) demonstrated signific
217 5 was also evident with Dmu, but the overall SLC- and L chain-dependent requirements for Dmu maturati
219 We present design rules for IDPs possessing SLCs that phase separate into diverse assemblies within
220 d allowed for discrimination between primary SLCs and less frequent, long-latency startle responses (
221 teresting family of solute carrier proteins (SLCs), some of which have been suggested as being involv
222 growth factor I, and LH, 40% of the putative SLCs came to express 3betaHSD and to synthesize testoste
223 which LCs had been eliminated, the putative SLCs colonized the interstitium and subsequently express
225 acid human orphan G-protein-coupled receptor SLC-1 expressed in HEK293 cells binds MCH with sub-nanom
227 dition, we demonstrate that the MCH receptor SLC-1 is expressed in adipocytes, suggesting that fat ce
233 n-sensitive B cell sticking does not require SLC or MIP-3beta signaling, and occurs efficiently in SL
234 we examined short-latency startle responses (SLCs) in larval zebrafish and tested the hypothesis that
240 raphs of consecutive patients with active TB SLC seen at a single tertiary referral center with 6 mon
242 risk factors for paradoxical worsening of TB SLC (OR 7.555, 95% CI: 1.78-32.02; P = 0.006; OR 7.434,
243 hat the chemokine CCL21 (also known as TCA4, SLC, 6Ckine), a ligand for the chemokine receptor CCR7,
248 tic defect in the expression of SLC and that SLC mediates the entry of naive T cells and antigen-stim
253 he Malvasia as the more effective one), that SLC led to the lowest level of TAC and that 8 buds/plant
257 t is determined by its Ig components and the SLC, we investigated the regulation of pre-BCR surface e
261 re of GAS strains associated with ARF in the SLC region, 964 mucoid and nonmucoid pharyngeal isolates
263 tion represents a deletion that includes the SLC gene expressed in secondary lymphoid organs and the
266 ency and the precision in the latency of the SLC field potentials were linearly correlated to the lat
267 e pre-BCR also signals downregulation of the SLC genes (VpreB and lambda5), thereby limiting this exp
269 This Perspective provides an overview of the SLC superfamily, including their biochemical and functio
272 sing this replicase, we demonstrate that the SLC-like structure in Fny-CMV plays a role similar to th
274 ow that the "smart" fields learned using the SLC method can achieve robust manipulation of supercondu
276 toplasts, we found that BMV RNA3s with their SLCs replaced with two different CMV SLCs were defective
277 s T cell-attracting chemokine (CTACK), three SLC, and four ELC genes or pseudogenes are present in so
281 lectin-mediated enhancement of chemotaxis to SLC was observed for all naive lymphocytes and effector/
286 tin-sensitive Na(+)-Li(+) counter-transport (SLC) activity, an established marker for hypertension.
289 FAF) images of eyes affected with tubercular SLC from the acute stage until resolution of lesions usi
290 o both primary and MK cells, the tumorigenic SLC-1 cell line did not accumulate in a specific cell cy
291 otypes share a duplication that includes two SLC genes, which demonstrate different expression patter
296 ique for liver parenchymal transection using SLC and UD in noncirrhotic livers is safe and may provid
297 of CA9 in PDAC cells, or inhibited CA9 with SLC-0111, incubated them with gemcitabine, and assessed
299 site immunization of tumor-bearing mice with SLC gene-modified DCs pulsed with tumor lysate elicited
300 we showed MHC class II-positive cells within SLC-staining lymphatic channels in the mouse dermis.