ライフサイエンスコーパス: SNB

1 SNB is an appropriate initial alternative to routine sta

2 SNB motoneuron number was increased in female Bax-/- mic

3 SNB motoneurons were axotomized bilaterally and BDNF or

4 SNB motoneurons were retrogradely labeled with cholera t

5 SNB motoneurons were retrogradely labeled with cholera t

6 SNB resistance in wheat is controlled by several quantit

7 SNB techniques were not associated with higher rates of

8 0 mm in thickness was improved if they had a SNB, with significantly improved disease-free and DMFS.

9 Pre-ACA SNB quartile did not predict changes in PSI-90 post-ACA.

10 B only); if the SNs were pN1, completion AD (SNB + AD) was usually performed.

11 Adding SNB to ePLND improves BCR-free survival, although the pr

12 egression models tested the impact of adding SNB (either with the hybrid tracer or with free ICG) on

13 nificantly from the outcome after additional SNB.

14 eral nucleus (RDLN), nor did the drug affect SNB soma size in the absence of androgen treatment.

15 xhibiting a high level of resistance against SNB.

16 for the study; of these, 397 (62.8%) had an SNB.

17 Patients who did not have an SNB were at higher risk of locoregional recurrence (HR,

18 tly obtained in patients who did not have an SNB.

19 Preoperative US data and SNB results were analyzed for patients enrolled at 20 ce

20 in UNC-104, a neuronal-specific kinesin, and SNB-1, a synaptic vesicle-associated protein termed syna

21 pathologically measured excision margins and SNB on local and locoregional disease control in patient

22 ), NCI-H23 (lung), SK-MEL-28 (melanoma), and SNB-7 (CNS).

23 ph node basins were evaluated by FDG-PET and SNB in 70 assessable patients.

24 naffected by the absence of Bax protein, and SNB motoneuron number is dissociated from target muscle

25 MZ resistant GBM cell lines, U373(TMZ-R) and SNB-19(TMZ-R) cells, in the presence of TMZ than unmodif

26 0, 0.25, and 0.15 in UWR2, UWR3, U251MG, and SNB-19 cells, respectively.

27 e glioma cell lines (UWR2, UWR3, U251MG, and SNB-19).

28 Transient transfections of U373MG and SNB-19 with wild-type p27 and a degradation-resistant p2

29 Using two glioma cell lines, U373MG and SNB-19, we have demonstrated that SF/HGF stimulation all

30 ampling procedure from hereon referred to as SNB.

31 We prospectively assigned SNB after primary chemotherapy to 353 consecutive cT2 cN

32 n androgen receptor expression in axotomized SNB motoneurons, and examined whether delayed applicatio

33 elayed application of BDNF to the axotomized SNB motoneurons restored the AR-LI to the intact level.

34 ere asthma patients not receiving biologics (SNB, N = 178).

35 Experience with sentinel node biopsy (SNB) after neoadjuvant chemotherapy is limited.

36 ndations on the use of sentinel node biopsy (SNB) for patients with early-stage breast cancer.

37 Sentinel node biopsy (SNB) has led to an increase in the detection of micromet

38 the implementation of sentinel node biopsy (SNB) in robot-assisted radical prostatectomy with extend

39 tastasis determined by sentinel node biopsy (SNB) is an important prognostic factor for T1 melanoma.

40 Worldwide, sentinel node biopsy (SNB) is now a standard staging procedure for most patien

41 The benefit of adding sentinel node biopsy (SNB) to extended pelvic lymph node dissection (ePLND) re

42 Sentinel lymph node (SN) biopsy (SNB) has proven to be a valuable tool for staging melano

43 If sentinel node (SN) biopsy (SNB) is accurate in this setting, completion node dissec

44 hologic results (sentinel lymph node biopsy [SNB] or axillary lymph node dissection [ALND]) were comp

45 use the disease Stagonospora nodorum blotch (SNB) in wheat.

46 Stagonospora nodorum blotch (SNB) is an economically important wheat disease caused b

47 Septoria nodorum blotch (SNB), a disease caused by the necrotrophic fungal pathog

48 Septoria nodorum blotch (SNB), caused by Parastagonospora nodorum, is a disease o

49 am68 colocalize in Sam68-SLM nuclear bodies (SNBs), while transfected Sik and Sam68 are localized dif

50 d the spinal nucleus of the bulbocavernosus (SNB) and dorsolateral nucleus (DLN) in rats.

51 , the spinal nucleus of the bulbocavernosus (SNB) and the dorsolateral nucleus (DLN), and for the sex

52 f the spinal nucleus of the bulbocavernosus (SNB) and the dorsolateral nucleus (DLN), both sexually d

53 n the spinal nucleus of the bulbocavernosus (SNB) and their target muscles in the perineum, bulbocave

54 n the spinal nucleus of the bulbocavernosus (SNB) express androgen receptors and innervate striated m

55 rphic spinal nucleus of the bulbocavernosus (SNB) in male and female gerbils from known intrauterine

56 The spinal nucleus of the bulbocavernosus (SNB) is a medially located, bilaterally organized sexual

57 n the spinal nucleus of the bulbocavernosus (SNB) motoneurons of adult male rats.

58 rats, spinal nucleus of the bulbocavernosus (SNB) motoneurons shrink after castration and are restore

59 n the spinal nucleus of the bulbocavernosus (SNB) of rats extends postnatally and is controlled by an

60 n the spinal nucleus of the bulbocavernosus (SNB) of the Mongolian gerbil is achieved by two periods

61 n the spinal nucleus of the bulbocavernosus (SNB) than do females.

62 f the spinal nucleus of the bulbocavernosus (SNB), a sexually dimorphic motor nucleus in the lumbar s

63 n the spinal nucleus of the bulbocavernosus (SNB), an androgen-dependent population of motoneurons in

64 n the spinal nucleus of the bulbocavernosus (SNB), dorsolateral nucleus and retrodorsolateral nucleus

65 : the spinal nucleus of the bulbocavernosus (SNB), in which neuron number is greater in males; the re

66 itive spinal nucleus of the bulbocavernosus (SNB).

67 nts were categorized into safety-net burden (SNB) quartiles.

68 ith fluorodeoxyglucose (FDG) PET followed by SNB.

69 lbocavernosus muscle, which is innervated by SNB motoneurons, was approximately 50% larger in 2M than

70 recurrence (14.3%) in a node basin missed by SNB.

71 at the time of FDG-PET imaging: 17 proved by SNB (24.3%) and one by follow-up examination (1.4%).

72 ensitivity genes play major roles in causing SNB.

73 t, when performed by experienced clinicians, SNB appears to be a safe and acceptably accurate method

74 ization, we recorded ipsi- and contralateral SNB motor nerve activity following unilateral spinal sti

75 n caused regressive changes in contralateral SNB motoneurons: Soma size and dendritic length were bot

76 and examined the morphology of contralateral SNB motoneurons.

77 ether delayed application of BDNF to the cut SNB axons can completely reverse the axotomy-induced los

78 We depleted SNB motoneurons on one side only of the spinal cord by u

79 xtremely local effects within the developing SNB arbor, as well as transient alterations in somal gro

80 nce the morphology of the sexually dimorphic SNB neuromuscular system.

81 rvival rate was 80.5% and 69.9% in the ePLND+SNB and ePLND groups, respectively.

82 In the ePLND+SNB group, only the number of positive nodes was an inde

83 probability of BCR-free status in the ePLND+SNB group, whereas the ePLND group was performing as pre

84 ncer Center nomogram was higher in the ePLND+SNB than in the ePLND group.

85 obtained from multicenter studies evaluating SNB before systemic therapy and suggest that the sentine

86 Candidate region analysis for SNB resistance revealed 35 genes of putative interest wi

87 We found seven significant associations for SNB resistance/susceptibility distributed over chromosom

88 tients with T1 melanoma being considered for SNB.

89 o better select patients with T1 disease for SNB.

90 distant metastasis-free survival (DMFS) for SNB patients with T2 and T3 melanomas (P = 0.041).

91 t Plains region of the US, was evaluated for SNB resistance and necrotrophic effectors (NEs) sensitiv

92 ups indicated a significantly better MSS for SNB patients with T2 and T3 melanomas (>1.0 to 4.0 mm th

93 vator ani (LA), which is a target muscle for SNB motoneurons.

94 Two new QTLs for SNB resistance/susceptibility at the seedling stage were

95 Of 343 patients who had SNB and axillary dissection, the sentinel nodes were pos

96 7%, respectively; P = 0.441) and across high SNB hospitals within expansion versus nonexpansion state

97 after primary chemotherapy because the high SNB false negative rate might lead to poorer outcomes.

98 Lastly, use of hybrid SNB was associated with lower rates of biochemical recur

99 Conclusion: The implementation of hybrid-SNB technique with ICG-(99m)Tc-nanocolloid in prostate c

100 The hybrid-SNB group (odds ratio, 1.61; 95%CI, 1.18-2.20; P = 0.002

101 ICG-SNB group, and 351 (20.9%) in the hybrid-SNB group.

102 dictor of nodal involvement, whereas the ICG-SNB group did not reach independent predictor status whe

103 in the non-SNB group, 161 (9.6%) in the ICG-SNB group, and 351 (20.9%) in the hybrid-SNB group.

104 SNB only patients vs 86% (95%CI: 78-95%) in SNB + AD patients; 10-year DFS 79% (95%CI: 68-92%) vs 69

105 omparison: 10-year OS 89% (95%CI: 81-99%) in SNB only patients vs 86% (95%CI: 78-95%) in SNB + AD pat

106 male copulatory behavior via alterations in SNB motoneuron morphology, and thus support maternal lic

107 asure the effects of expansion and change in SNB on PSI-90.

108 MT-MMP protein was detected in SNB-19 and U251 cell lines only after ConA treatment.

109 on retrograde tracing, the sex difference in SNB cell number is eliminated in Bax-/- mice.

110 R2A and R2B mRNA expression in SNB cells was not affected by androgen manipulations.

111 her NMDA receptor activation was involved in SNB dendritic growth and whether the estrogenic support

112 2M males did not differ from 2F males in SNB motoneuron number, but the bulbocavernosus muscle, w

113 tration reduced the expression of R1 mRNA in SNB motoneurons, an effect that was blocked by androgen

114 RNA resulted in enhanced exon recognition in SNB-19 glioblastoma cells.

115 rall (OS) and disease-free (DFS) survival in SNB only vs SNB + AD patients, assessed by Kaplan-Meier

116 The amount of MT-MMP mRNA was unchanged in SNB-19 after ConA treatment, and the MT-MMP mRNA level i

117 ver, MT-MMP mRNA expression was unchanged in SNB-19 cells.

118 Transfected Sik phosphorylates Sam68 in SNBs in HT29 cells and in the nucleoplasm of NMuMG cells

119 6 days of treatment did not further increase SNB motoneuron numbers.

120 all improvement in patient safety, increased SNB was associated with increased safety events in expan

121 Bcl-2 overexpression significantly increased SNB cell number in females, overall cell density of AVPV

122 entionally penalize hospitals with increased SNB following Medicaid expansion.

123 Maternal licking influences SNB motoneuron number, with reductions in licking result

124 f BDNF was not different from that in intact SNB motoneurons.

125 cible ets-1 gene was stably transfected into SNB-19 cells using a tetracycline repressor system.

126 adish peroxidase conjugate (CT-HRP) to label SNB cells.

127 (GI(5)(0) = 0.018 muM), CNS cancer cell line SNB-75 (GI(5)(0) = 0.0159 muM), ovarian cancer cell line

128 LM/SNB is a safe, low-morbidity procedure for staging the r

129 LM/SNB should become standard care for staging the regional

130 30-case learning phase and 25 additional LM/SNB cases, the accuracy of LM/SNB continues to increase

131 The low (10.1%) complication rate after LM/SNB increased to 37.2% with the addition of CLND; CLND a

132 mphatic mapping and sentinel node biopsy (LM/SNB) for staging the regional nodal basin of patients wi

133 The rate of false-negative LM/SNB during the trial phase, as measured by nodal recurre

134 additional LM/SNB cases, the accuracy of LM/SNB continues to increase with a center's experience.

135 Since our introduction of LM/SNB in 1990, this technique has been widely adopted and

136 The accuracy of LM/SNB was determined by comparing the rates of SN identifi

137 Early morbidity of LM/SNB was evaluated by comparing complication rates betwee

138 CLND for nodal recurrence, or to WE plus LM/SNB with immediate CLND for SN metastasis.

139 tment approaches: wide excision (WE) plus LM/SNB with immediate complete lymphadenectomy (CLND) for s

140 and the incidence of SN metastases in the LM/SNB group versus the subsequent development of nodal met

141 node-positive breast cancer after NAC, a low SNB FNR (8.4%) can be achieved with mandatory use of IHC

142 F alpha-receptor had fewer than half as many SNB motoneurons than did wild-type males and no more tha

143 NB dendritic morphology is normally mature), SNB motoneurons were retrogradely labeled with cholera t

144 ll lines, such as DBTRG MG, Hs 683, U-87 MG, SNB-19, and A-172, are very susceptible to hIL13-PE38QQR

145 nd that adult 2M female gerbils had 16% more SNB motoneurons than did 2F females.

146 New SNB motoneurons appeared within 2 days of delayed TP rep

147 No SNB-only patient developed axillary failure.

148 predictor status when compared with the non-SNB group (odds ratio, 1.35; 95%CI, 0.89-2.03; P = 0.1).

149 the final analysis: 1,168 (69.5%) in the non-SNB group, 161 (9.6%) in the ICG-SNB group, and 351 (20.

150 , 0.76, P = 0.035) than were seen in the non-SNB group.

151 tomy reflects the decrease in the ability of SNB motoneurons to accumulate androgens.

152 est whether axotomy decreases the ability of SNB motoneurons to accumulate androgens.

153 ion and compared with histologic analyses of SNB specimens and clinical follow-up examination.

154 r patients, stratified by the application of SNB.

155 sought to assess the therapeutic benefit of SNB in a large, nonrandomized patient cohort.

156 re, that the estrogen-sensitive component of SNB dendritic development requires their activation.

157 ence is caused by hormone-regulated death of SNB motoneurons and their target muscles.

158 ct of maternal licking on the development of SNB dendritic morphology.

159 nvolved in sexually dimorphic development of SNB motoneuron number and that target muscle survival pe

160 Dendritic development of SNB motoneurons requires the action of both androgens an

161 olved in the normal postnatal development of SNB motoneurons, and whether the effect of estradiol on

162 cell death and ultimately the development of SNB.

163 Sexual dimorphism of SNB motoneuron number developed completely normally in C

164 effects are limited to the initial growth of SNB dendrites through 4 weeks of age.

165 Somal area and dendritic length of SNB motoneurons in MK-801-treated, intact males were bel

166 explained the additive and complex nature of SNB resistance.

167 atment significantly increased the number of SNB motoneurons with AR-positive nuclei at P7.

168 ionate (TP) treatment resulted in numbers of SNB motoneurons comparable to those seen in intact males

169 The percentage of SNB motoneurons expressing medium or high AR-LI was the

170 my significantly decreased the percentage of SNB motoneurons to accumulate tritiated testosterone or

171 nter trials in which the test performance of SNB was evaluated with respect to the results of ALND (c

172 trophic factors in the androgenic rescue of SNB motoneurons and further suggest that trophic factor

173 identified patients with negative results of SNB, when done under the direction of an experienced sur

174 Sensitivity of SNB for detection of occult regional lymph node metastas

175 ivered either into the perineum (the site of SNB target muscles) or systemically.

176 ts suggest that androgen affects the size of SNB motoneurons by influencing their expression of the N

177 TFRalpha prevented the androgenic sparing of SNB motoneurons when antagonists were delivered to the p

178 growth and whether the estrogenic support of SNB dendritic growth was dependent on the activation of

179 and levator ani muscles, the main targets of SNB motoneurons, was not affected in either CNTF or CNTF

180 included in future guidelines on the use of SNB after NAC in this setting.

181 vailable through February 2004 on the use of SNB in early-stage breast cancer.

182 and ePLND with or without additional use of SNB, either with the hybrid tracer indocyanine green (IC

183 eason, we aimed to define the added value of SNB (with different tracer modalities) to ePLND in the i

184 0) after primary chemotherapy can be offered SNB (with no further axillary treatment if the SNs are n

185 /neoadjuvant systemic therapy may be offered SNB.

186 /neoadjuvant systemic therapy may be offered SNB.

187 rons, and whether the effect of estradiol on SNB dendritic growth could be explained by an indirect a

188 the effect of this technologic evolution on SNB in the head and neck region.

189 ients with axillary metastases identified on SNB.

190 Gap junctions on SNB and DLN motoneurons are androgen sensitive; the numb

191 The optimal SNB identification rate (IR) >/= 90% and false-negative

192 A for predicting positive results at ALND or SNB was 71%-75%.

193 Compared with OBS patients, SNB patients demonstrated improved disease-free survival

194 provide clear indications on when to perform SNB in T1 disease and stress an individualized approach

195 he outcomes for those who underwent WLE plus SNB (n = 2909) were compared with the outcomes for patie

196 In male rats, SNB motoneurons exhibit a biphasic pattern of dendritic

197 seen previously, among saline-treated rats, SNB somata of T-treated castrates were significantly lar

198 2020 guidelines do not recommend SNB in most cN1 patients with clear SNs after primary ch

199 tor antagonists did not significantly reduce SNB motoneuron number when higher doses were injected sy

200 ays for serum/plasma (IMMULITE and SimulTRAC-SNB) for B12 analysis in human milk.

201 25 +/- 108% (range 116-553%) using SimulTRAC-SNB, most likely due to the presence of excess HC.

202 25 +/- 108% (range 116-553%) using SimulTRAC-SNB, most likely due to the presence of excess HC.

203 act by means of supraspinal input to support SNB motoneuron development.

204 he trophic effect of estradiol on supporting SNB dendritic growth, indicating that estrogens do not a

205 aptic proteins liprin-a/SYD-2, Synaptobrevin/SNB-1, RAB-3 and Endophilin/UNC-57 in remodeling GABAerg

206 Ngamma) on the glioblastoma cell lines T98G, SNB-19 and U-373, focusing on the ability of IFNgamma to

207 We found that SNB motoneurons developed AR immunoreactivity at first a

208 In situ hybridization indicated that SNB motoneurons express mRNA for the NMDA receptor subun

209 Data suggest that SNB is associated with less morbidity than ALND, but the

210 The SNB IR was 87.6% (127 of 145; 95% CI, 82.2% to 93.0%), a

211 The SNB IR was 87.6%, and in the presence of a technical fai

212 the DLN shared characteristics with both the SNB and the RDLN.

213 using the associated markers to enhance the SNB resistance in hard winter wheat.

214 significantly different for patients in the SNB and OBS groups.

215 atment, more motoneurons were labeled in the SNB following injection of a retrograde tract tracer int

216 er motoneurons, dendritic development in the SNB involves NMDA receptors and, furthermore, that the e

217 at androgen receptor immunoreactivity in the SNB motoneurons decreases after axotomy and returns to n

218 ation of androgen receptor expression in the SNB motoneurons; and (iii) treatment with brain-derived

219 Mean soma size in the SNB of Bax-/- females is reduced, however, and there is

220 cline in the density of soma labeling in the SNB of castrated males but did not reverse any other eff

221 s a subpopulation of very small cells in the SNB of female knock-outs.

222 Thus, new motoneurons appeared in the SNB of prepubertally castrated male Mongolian gerbils wi

223 In contrast, a sex difference in the SNB was absent in CNTFRalpha -/- animals: male mice lack

224 ed a 23% reduction in dendritic arbor in the SNB, an effect that was especially pronounced in the ros

225 r sexually dimorphic motoneuron death in the SNB, and motoneurons rescued by Bax deletion project the

226 interneurons; coupling was bilateral in the SNB.

227 e first was to determine the response of the SNB in prepubertally castrated male gerbils receiving de

228 is crucial for continuous improvement of the SNB resistance.

229 We exploited these features of the SNB system to identify endogenously produced trophic fac

230 role of gap junctions in the activity of the SNB.

231 ng electrodes were placed bilaterally on the SNB motor nerves.

232 01 treatment blocked this effect of T on the SNB.

233 is study demonstrates that (i) silencing the SNB neuromuscular system with tetrodotoxin did not affec

234 s a dependent variable demonstrated that the SNB, mandibular plane angle, and the inclination of the

235 esults indicate that unilateral input to the SNB may be differentially modulated to produce functiona

236 by means of descending spinal tracts to the SNB was involved in the normal postnatal development of

237 Their SNB and ramus heights were also significantly improved a

238 However, when hospitals increased their SNB by 5%, they incurred significantly more safety event

239 ase and stress an individualized approach to SNB that considers all clinicopathologic risk factors.

240 unt for bias due to non-random assignment to SNB vs SNB + AD.

241 Conversely, compared to SNB, Mepolizumab patients were predominantly older males

242 Compared to SNB, Omalizumab patients were younger, diagnosed with as

243 e highly invasive, but the sense-transfected SNB-19 clones were much less invasive; the antisense-tra

244 ally received no further axillary treatment (SNB only); if the SNs were pN1, completion AD (SNB + AD)

245 Four weeks after saporin treatment, SNB motoneurons contralateral to the saporin injection w

246 advantage of diverse host targets to trigger SNB susceptibility in wheat.

247 planned) or are pregnant should not undergo SNB.

248 planned) or are pregnant should not undergo SNB.

249 s in the development cohort, 1,635 underwent SNB; 108 patients (6.6%) were SN positive.

250 ead and neck melanoma patients who underwent SNB at The Netherlands Cancer Institute between 1993 and

251 d disease-free (DFS) survival in SNB only vs SNB + AD patients, assessed by Kaplan-Meier and compared

252 bias due to non-random assignment to SNB vs SNB + AD.

253 At either postnatal day (P) 28 (when SNB dendritic length is normally maximal) or P49 (when S

254 the best local and locoregional control when SNB was coupled with a more than 16-mm histologic excisi

255 tic length is normally maximal) or P49 (when SNB dendritic morphology is normally mature), SNB motone

256 nts indicate an extensive syncytium in which SNB motoneurons are coupled with each other and neighbor

257 pective randomized controlled trial in which SNB was compared with axillary lymph node dissection (AL

258 e polymorphism (SNP) markers associated with SNB resistance and effectors sensitivity.

259 ical prostatectomy and ePLND with or without SNB (184 and 736 patients, respectively).