ライフサイエンスコーパス: SPME

1 SPME devices prepared on PBT were evaluated in terms of

2 SPME is an established sample preparation approach that

3 SPME-GC-MS was used for sampling, sample preparation, an

4 SPME-GC/QTOF was selected as the most suitable methodolo

5 SPME-MS proved to be advantageous in use due to better d

6 A SPME-GC-MS method was adapted and validated in order to

7 These results present a SPME methodology, which may be applied as a quality cont

8 interface and a custom holder accommodating SPME probes were built in house, with the latter contrib

9 Although SPME fibers have been used for years, their potential fo

10 In this article, the use of an SPME technique is reported for the first time for direct

11 ision, and accuracy while both CBS-MS/MS and SPME-LC-MS/MS methods achieved limits of quantitation be

12 mouth conditions by using human saliva, and SPME-GC/MS analysis.

13 ls were compared: PE strips, POM strips, and SPME fibers.

14 As SPME allows for nonlethal sampling, the same group of an

15 Commercially available SPME fibre coated with polydimethylsiloxane (PDMS) was u

16 this paper, we present a fluorescence-based SPME method and a prototype of a portable fluorometer th

17 The reusability and robustness of PIL-based SPME for RNA analysis represents a significant advantage

18 The optimized PIL-based SPME method purified a high quantity of mRNA from crude

19 Furthermore, the PIL-based SPME method was successfully applied for the extraction

20 Following PIL-based SPME of DNA from a dilute cell lysate, the qPCR amplific

21 ternative solid phase microextraction-based (SPME) chemical biopsy approach as a viable method for ac

22 then thawed at 25 degrees C for 5 min before SPME extraction was performed.

23 ocompatible solid phase microextraction (Bio-SPME) has shown great potential in metabolomics for in s

24 e direct coupling of biocompatible SPME (Bio-SPME) fibers to mass spectrometry via nanoelectrospray i

25 interface to couple biocompatible SPME (Bio-SPME) fibers to MS systems for direct electrospray ioniz

26 he amounts of peptides extracted by such Bio-SPME chemical biopsy tools are deemed too low for quanti

27 Given that Bio-SPME-nano-ESI efficiently integrates sampling with analy

28 Our results demonstrated that Bio-SPME-OPP-MS efficiently integrates sampling/sample clean

29 e instrument uses thin coated, biocompatible SPME fibers, which we have previously presented as a che

30 s a robust interface to couple biocompatible SPME (Bio-SPME) fibers to MS systems for direct electros

31 present the direct coupling of biocompatible SPME (Bio-SPME) fibers to mass spectrometry via nanoelec

32 then the labelled volatiles were analyzed by SPME-GC-MS.

33 ntification of CLA and volatile compounds by SPME coupled with CG-MS) during two months of storage at

34 c profiles (by HPLC), volatile compounds (by SPME-GC/MS), antioxidant activity, and sensory propertie

35 olatility and polarity were only detected by SPME.

36 Aroma compounds were determined by SPME GC-MS.

37 aining in the liquid phase was determined by SPME-GC-MS.

38 sil Ocimum citriodorum Vis were evaluated by SPME-GC/MS.

39 Traditionally, analytes extracted by SPME fibers are desorbed by washing with suitable solven

40 or volatile compounds (46.75%) identified by SPME-GC/MS.

41 s-only juices, 41 compounds were isolated by SPME, including 17 of the consensus volatiles.

42 mparative study of OSCs profiles obtained by SPME coupled to HPLC-UV and gas chromatography with flam

43 id-phase microextraction-gas chromatography (SPME-GC) data of a collection of 270 wines from Galicia

44 d-Phase Micro Extraction Gas Chromatography (SPME-GC-MS) technique and associated to the parallel IMS

45 The strategy adds robustness to the classic SPME methods for solid samples, by including a control s

46 zene (PDMS-DVB) and polyacrylate (PA) coated SPME fibers for the collection of nicotine and its metab

47 fter dosing, as extractions via thin coating SPME fibers do not affect the free concentration of the

48 Our results also indicate that thin coating SPME fibers provide a good way to measure drug distribut

49 e matrix, and a biocompatible C-8 commercial SPME fiber was used for extraction of DOX.

50 Unlike other systems to couple SPME sampling to ambient mass spectrometry, the interfac

51 rant when acquired using a 6-time cumulative SPME sampling approach.

52 MP for SNP detection as well as demonstrates SPME as a sample preparation tool for nucleic acid analy

53 n replicate analyses on the same derivatized SPME fiber and with sequential fiber sampling events, yi

54 Validation of the developed SPME-HPLC-MS/MS protocol in a surrogate brain matrix yie

55 With this development, SPME fibers can now be reproducibly loaded with derivati

56 ct immersion-solid phase microextraction (DI-SPME) was employed to capture the metabolome of living p

57 hromatography-mass spectrometry platform (DI-SPME- HPLC-ESI -MS) for determination of unconjugated fa

58 to gas chromatography mass spectrometry (DI-SPME-GC-MS) was optimized for nontarget screening of mig

59 by gas chromatography/mass spectrometry (DI-SPME-GC/MS).

60 The potential of in vivo DI-SPME in quantitative plant metabolomics was assessed by

61 atile production in intact fruit, in vivo DI-SPME represents an attractive approach for global plant

62 compare analytical precision when different SPME sampling modes are employed.

63 matrix compatibility, make the use of direct SPME very practical as a quantification approach and the

64 This preliminary assessment of direct SPME-MS showed high sensitivity (ng/mL), acceptable repr

65 y controlled solid-phase microextraction (EC-SPME) using a electro-synthesised nanostructure conducti

66 measured using solid-phase micro extraction (SPME).

67 s by headspace solid phase micro extraction (SPME-GC-MS), and photobleaching of photosensitizers in m

68 re explored by solid phase micro-extraction (SPME) and gas chromatography coupled to mass spectrometr

69 antified using Solid Phase Micro-Extraction (SPME) based on a sorptive polymer such as polydimethylsi

70 s monitored by solid phase micro-extraction (SPME) GC-MS.

71 Finally, the proposed thin-film SPME devices made on a PBT were evaluated by conducting

72 l determination of 2-phenoxyethanol in fish, SPME being more sensitive and automated and SDME with lo

73 or SDME were 0.2 and 0.62 mug mL(-1) and for SPME were 0.18 and 0.56 mug mL(-1), respectively.

74 AF being used as a particle immobilizer for SPME, an assessment of the analyte uptake rate and extra

75 lved generating gas-phase ions directly from SPME fibers without the need for any additional sample p

76 ce above a solid or liquid sample (headspace SPME), or to directly sample a liquid (immersion SPME).

77 protected solid-phase microextraction (HFLMP-SPME) followed by gas chromatography- flame ionization d

78 HS-SPME and LLE-GC/MS analyses revealed that metabolism of

79 HS-SPME coupled with in-situ derivatization was more straig

80 HS-SPME-GC-MS was used to sample and analyse volatile compo

81 HS-SPME-MS-enose turned out to be a fast, cost-effective an

82 This study applies a HS-SPME-MS-enose in combination with chemometrics to obtain

83 GC-FID/MS (after HS-SPME and ultrasonic solvent extraction) and targeted HPL

84 An HS-SPME method was developed using multivariate experimenta

85 An HS-SPME-GC-MS method and a recently developed HPLC-MS/MS me

86 An HS-SPME-GC-MS method was optimized for their quantitation i

87 measured using the sensory technique and HS-SPME-GC/MS analyses.

88 eted methods, i.e. (1)H NMR, LC-HRMS, and HS-SPME/MS-eNose, combined with chemometrics, were used to

89 S, while the flavor was mapped via aroma (HS-SPME-GC-MS) and generic descriptive analysis (trained pa

90 troscopic techniques ((1)H NMR, FTIR-ATR, HS-SPME/GC-MS).

91 ort and beer flavour-related compounds by HS-SPME followed by GC-MS quantification, no generalized co

92 sis (AEDA): volatile isolates obtained by HS-SPME from an aqueous extract and by Stir-Bar Sorptive Ex

93 Volatile compounds were analysed by HS-SPME GC-MS; an expert panel performed sensory analysis u

94 d, stabilised at five RHs and analysed by HS-SPME-GC-MS for volatiles.

95 ality rice cultivars were investigated by HS-SPME-GC-MS to define fingerprinting and identify chemica

96 in two consecutive years were obtained by HS-SPME-GC-MS.

97 addition, volatiles were characterized by HS-SPME-GC-MS.

98 6 days germination were characterized by HS-SPME-GC-MS/O.

99 ure mediums were isolated and analysed by HS-SPME-GC/MS.

100 ation of flavor volatiles was measured by HS-SPME-GC/MS.

101 ion areas for Italian sparkling wines, by HS-SPME-GCxGC-TOF-MS and multivariate analysis.

102 e of volatile aroma compounds isolated by HS-SPME.

103 raction combined with gas chromatography (HS-SPME/GC), fluorescence and circular dichroism (CD) spect

104 oupled to a mass spectrometric detection (HS-SPME-GC-MS) as well as headspace extraction in combinati

105 he effect of fiber-sample distance during HS-SPME in pre-equilibrium conditions.

106 , to improve the method robustness during HS-SPME studies, we suggest specifying the fiber penetratio

107 early impacts the results obtained during HS-SPME when conditions are such that no equilibrium is rea

108 y headspace solid phase micro extraction (HS-SPME-GC-MS) on conventional roasted cocoa beans, ILR-CIS

109 n of MS-based metabolomic fingerprinting (HS-SPME-GC-MS) and chemometric tools has been implemented a

110 and optimized as effective parameters in HS-SPME.

111 n-isotope ratio mass spectrometry method (HS-SPME-GC-C-IRMS) was developed to measure the carbon isot

112 by headspace solid-phase microextraction (HS-SPME) and analysed by GC-FID.

113 ), Headspace Solid Phase Microextraction (HS-SPME) and Headspace Sorptive Extraction (HSSE), in combi

114 ng headspace solid-phase microextraction (HS-SPME) and separation/detection by gas chromatography-mas

115 by headspace solid-phase microextraction (HS-SPME) combined with gas chromatography-mass spectrometry

116 nd headspace solid-phase microextraction (HS-SPME) combined with gas chromatography-quadrupole mass s

117 on headspace solid-phase microextraction (HS-SPME) coupled to gas chromatography-triple quadrupole/ma

118 Headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry

119 of headspace solid phase microextraction (HS-SPME) coupled with the comprehensive two-dimensional gas

120 ng headspace solid phase microextraction (HS-SPME) equipped with gas chromatography and mass spectrom

121 ng headspace-solid phase microextraction (HS-SPME) followed by gas chromatography/quadrupole-mass spe

122 ic headspace solid-phase microextraction (HS-SPME) followed by thermal desorption gas chromatography-

123 ng headspace solid phase microextraction (HS-SPME) is an appropriate tool for authenticity assessment

124 nd headspace solid phase microextraction (HS-SPME) is described.

125 or headspace solid phase microextraction (HS-SPME) method in baby formula samples and detected using

126 Headspace solid phase microextraction (HS-SPME) technique and gas chromatography coupled to both m

127 by headspace solid-phase microextraction (HS-SPME) to identify the key volatile compounds in this typ

128 th headspace solid-phase microextraction (HS-SPME) two-dimensional gas chromatography time-of-flight

129 Headspace solid-phase microextraction (HS-SPME) was used in order to verified linalool enantiomeri

130 Head space solid phase microextraction (HS-SPME) with a 65 um divinylbenzene/polydimethylsiloxane (

131 ng headspace solid phase microextraction (HS-SPME) with multicomponent fiber as sampling technique, r

132 ng Headspace Solid-Phase MicroExtraction (HS-SPME), combined with GC-MS, to an aqueous extract obtain

133 ct headspace solid-phase microextraction (HS-SPME), it is important to reach the highest level of rep

134 nd headspace solid-phase microextraction (HS-SPME).

135 trometry in selected ion monitoring mode (HS-SPME-GC-SIM-MS) allowed quantitative determination of de

136 Moreover, HS-SPME/GC-MS analysis was used to identify potential marke

137 dspace solid phase microextraction-GC-MS (HS-SPME-GC-MS), headspace-GC-FID (HS-GC-FID) and stir bar s

138 CD) was conducted for the optimization of HS-SPME conditions. Under optimal conditions, a good linear

139 date the aromatic composition by means of HS-SPME coupled with GC-MS; ii) assess the polyphenolic con

140 volatile profiles identified by means of HS-SPME-GC-MS analysis, significantly differed in terms of

141 e was a good agreement between results of HS-SPME/GC and fluorescence spectroscopy regarding the safr

142 The results of HS-SPME/GC indicated that bovine serum albumin (BSA) had th

143 etermined by liquid-liquid-extraction- or HS-SPME-GC/MS at various stages in the winemaking process.

144 The most significant HS-SPME parameters, namely fibre polymer, ionic strength an

145 ion-gas chromatography-mass spectrometry (HS-SPME-GC-MS) in density sorted berries (1075-1119 kg m(-3

146 ion-gas chromatography-mass spectrometry (HS-SPME-GC-MS) method for the analysis of solid food sample

147 ion gas chromatography-mass spectrometry (HS-SPME-GC-MS) method for the quantification of 3-monochlor

148 to gas chromatography-mass spectrometry (HS-SPME-GC-MS) was applied to quantify four NAms in differe

149 ith gas chromatography-mass spectrometry (HS-SPME-GC-MS) was used to analyze the volatile compounds o

150 ion gas chromatography mass spectrometry (HS-SPME-GC-MS), identified 20 to 70 components depending up

151 ion-Gas Chromatography-Mass Spectrometry (HS-SPME-GC-MS).

152 ion gas chromatography mass spectrometry (HS-SPME-GC/MS).

153 and gas chromatography-mass spectrometry (HS-SPME-GC/MS).

154 by gas chromatography mass spectrometry (HS-SPME/GC-MS).

155 ectronic nose based on mass spectrometry (HS-SPME/MS-eNose) in combination with chemometrics was deve

156 in matrix composition and structure, the HS-SPME allows studying of matrix-related changes in foods.

157 ponse surface methodology to optimize the HS-SPME parameters; determined at; 45 min extraction time a

158 multiple extraction temperatures for the HS-SPME procedure proved to be an excellent alternative for

159 te the influence of the parameters on the HS-SPME technique.

160 was applied to insect samples before the HS-SPME-GC-MS analysis.

161 The HS-SPME-IMS is precise, selective and sensitive analytical

162 firmed by a quantitative analysis through HS-SPME-GC-MS.

163 y on wine volatome was investigated using HS-SPME-GC x GC-TOFMS.

164 A targeted approach using HS-SPME-GC-MS was performed to compare flavour compounds of

165 ms in red wine have been quantified using HS-SPME-GC-MS.

166 atile compound profile was examined using HS-SPME-GC-MS.

167 olatile organic compound production using HS-SPME-GC/MS analysis.

168 67 volatiles in PPIs were identified via HS-SPME-GC-MS/O.

169 ing coffee aroma and flavor obtained with HS-SPME of the ground coffee and in-solution SBSE/SPME samp

170 e analyzed with GC-FID and volatiles with HS-SPME-GC-MS and GC-O.

171 cally, chocolate aroma was profiled using HS/SPME-GC-MS for three different time and temperature comb

172 Direct immersion SPME limited the occurrence of the artifacts, which conf

173 An in vivo direct-immersion SPME sampling coupled to comprehensive two-dimensional g

174 ), or to directly sample a liquid (immersion SPME).

175 In SPME, a small probe coated with a biocompatible polymer

176 matical model for the processes occurring in SPME extraction of analyte(s) from an aqueous sample med

177 ed model captures the phenomena occurring in SPME, leading to a clearer understanding of this process

178 The obtained ionogel SPME fibers exhibited high extractability for aromatic v

179 line in-tube solid-phase microextraction (IT-SPME) to Cap-LC-DAD, the effect of the dilution can be s

180 vity and concentration-dependent signals, IT-SPME-Cap-LC responds to changes in the particle's hydrod

181 ffective materials as support to manufacture SPME biocompatible devices for a wide range of applicati

182 ls, analysed by solid-phase microextraction (SPME GC-MS).

183 raw state using solid-phase microextraction (SPME) and cooked state using simultaneous distillation e

184 traction (SPE), solid-phase microextraction (SPME) and gas chromatography (GC), and phenols by ultra-

185 ect coupling of solid phase microextraction (SPME) and mass spectrometry (MS) has shown its great pot

186 Solid-phase microextraction (SPME) and single-drop microextraction (SDME) in headspac

187 eadspace (SHS), solid-phase microextraction (SPME) and solvent-assisted flavour evaporation (SAFE) co

188 cultures using solid phase microextraction (SPME) and were analyzed using gas chromatography-mass sp

189 atography using solid phase microextraction (SPME) as a sample pre-treatment procedure.

190 s using in vivo solid-phase microextraction (SPME) chemical biopsy tool in combination with liquid ch

191 w generation of solid-phase microextraction (SPME) coatings based on polytetrafluoroethylene amorphou

192 reparing porous solid phase microextraction (SPME) coatings by the sputtering of silicon onto silica

193 sampling using solid-phase microextraction (SPME) coupled to gas chromatography-tandem mass spectrom

194 We used solid-phase microextraction (SPME) coupled with gas chromatography-mass spectrometry

195 headspace (HS) solid-phase microextraction (SPME) coupled with gas-chromatography mass spectrometry

196 lop a sensitive solid-phase microextraction (SPME) device for direct and rapid analysis of untreated

197 s new thin-film solid phase microextraction (SPME) devices prepared on plastic as potential single-us

198 nd evaluated as solid-phase microextraction (SPME) fiber coatings.

199 e (DART) probe, solid-phase microextraction (SPME) fiber, and the inlet of a high-resolution mass spe

200 65 mum DVB/PDMS solid phase microextraction (SPME) fiber.

201 ibution between solid-phase microextraction (SPME) fibers and water was used in this study to measure

202 es collected on solid-phase microextraction (SPME) fibers by mass spectrometry (MS).

203 To date, solid-phase microextraction (SPME) fibers used for in vivo bioanalysis can be too fra

204 rried out using solid-phase microextraction (SPME) followed by a comprehensive two-dimensional gas ch

205 re subjected to Solid Phase Microextraction (SPME) Gas Chromatography/Mass Spectrometry (GC/MS) analy

206 nfigurations of solid-phase microextraction (SPME) have been directly coupled to mass spectrometry, r

207 headspace (HS) solid-phase microextraction (SPME) in combination with gas chromatographic (GC) separ

208 irect immersion solid phase microextraction (SPME) in vegetables.

209 Solid-phase microextraction (SPME) is a well-known sampling and sample preparation te

210 Furthermore, solid-phase microextraction (SPME) is applied for the successful isolation of clinica

211 t of an in vivo solid-phase microextraction (SPME) method capable of analyzing drugs and metabolic pr

212 reported, this solid-phase microextraction (SPME) method delivered a robust 'Wonderful' volatile pro

213 Solid-phase microextraction (SPME) method parameters are explored, such as reduction

214 We developed a solid phase microextraction (SPME) method to quantify the cis- and trans-isomers of 4

215 n this study, a solid-phase microextraction (SPME) method was developed for the purification of mRNA

216 Solid phase microextraction (SPME) on-fiber derivatization methods have facilitated t

217 experiments by solid-phase microextraction (SPME) resulting in partitioning coefficients of solid-wa

218 hrough a unique solid phase microextraction (SPME) sampler.

219 Multiple solid-phase microextraction (SPME) sampling with GC-O located odour-active regions; G

220 cted, using the solid phase microextraction (SPME) technique, and HMF was quantified, using a piezoel

221 is coupled with solid-phase microextraction (SPME) to facilitate rapid extraction and detection of th

222 uid (PIL)-based solid-phase microextraction (SPME) was applied for the extraction and purification of

223 m that combines solid-phase microextraction (SPME) with desorption electrospray ionization mass spect

224 ect coupling of Solid-Phase Microextraction (SPME) with mass spectrometry, based on thermal desorptio

225 Solid phase microextraction (SPME), polydimethylsiloxane stir bar sorptive extraction

226 -MSD) employing solid-phase microextraction (SPME).

227 sampling using solid-phase microextraction (SPME).

228 with the use of solid-phase microextraction (SPME).

229 rain studies is solid-phase microextraction (SPME).

230 those of other solid-phase microextraction (SPME-MS) approaches while dramatically minimizing the am

231 The miniaturized SPME probe developed for integrated in vivo sampling/sam

232 lid-phase microextraction-transmission mode (SPME-TM) device made of poly(etheretherketone) (PEEK) me

233 id Phase Micro Extraction-Transmission Mode (SPME-TM) is a technology conceived as an effective syner

234 nalysed using spectrophotometry-UV and GC-MS-SPME, respectively.

235 To address this limitation, a new SPME device is herein presented which incorporates an ex

236 Moreover, the new SPME probes were used to validate an analytical method f

237 - and solvent-assisted desorption, these new SPME probes will properly suit various metabolomics appl

238 echnique combines the attractive features of SPME microsampling using minimal sample volumes with the

239 grees C), and the extraction performances of SPME fibers with 1.0 or 2.0 mum of sputtered silicon wer

240 artifacts, which confirms the suitability of SPME for in vivo applications.

241 In this work, we report the use of SPME and liquid chromatography-mass spectrometry for unt

242 The use of SPME-GC-MSD is an effective method to detect volatiles i

243 ection via preloading internal standard onto SPME fibers and signal integration in scan-by-scan mode.

244 romas was followed by an -in vivo intra-oral SPME approach.

245 exposure was studied by means of intra-oral SPME/GC-MS using three different panellists.

246 nfluences using matrix-compatible overcoated SPME fiber for quantitative analysis of pyrethroids in d

247 c ionic liquid (PIL) and a polyacrylate (PA) SPME sorbent coating was optimized to enhance the extrac

248 PEEK SPME-TM devices proved to be robust and were therefore u

249 ternal standards and sampled using gas-phase SPME.

250 This research highlights plastic SPME-TM's potential usefulness as a method for rapidly s

251 r studied PILs and a commercial polyacrylate SPME fiber.

252 In this study, we present SPME-TM as a novel tool for the ultrafast enrichment of

253 Finally, the recessed SPME device was applied to an on-site application for th

254 ME of the ground coffee and in-solution SBSE/SPME sampling combined with GC-MS to evaluate their comp

255 s spectrometry without compounds separation (SPME-MS) was used for differentiation of white as well a

256 rete analyses on different areas of a single SPME fiber device for up to three technical replicate me

257 lations of local depletion of DOX by a solid SPME coating.

258 Some SPME extraction parameters were optimized.

259 action-gas chromatography-mass spectrometry (SPME-GC-MS) and two-dimensional GC-MS.

260 action gas chromatography-mass spectrometry (SPME-GC-MS).

261 action-Gas Chromatography/Mass Spectrometry (SPME-GC/MS).

262 action-Gas Chromatography-Mass Spectroscopy (SPME-GC-MS), High-Performance Liquid Chromatography (HPL

263 Of the studied SPME sorbent coatings, the PIL containing carboxylic aci

264 In this research, we test SPME fibers with C8-SCX, C18, and HLB coatings with our

265 Finally, drone TF-SPME sampling of an anthropogenically impacted watercour

266 th thin film solid phase microextraction (TF-SPME) and liquid chromatography tandem mass spectrometry

267 ), thin-film solid-phase microextraction (TF-SPME) sampler was developed.

268 Two types of TF-SPME passive samplers, including a retracted thin film d

269 This report is the first to show that SPME can contribute to a broader understanding of deep s

270 Aiming to improve peptide extraction by the SPME sorbent while still preventing protein adsorption,

271 and computational simulation describing the SPME process is required for experimentalists to underst

272 hanol was 12 h for the SDME and 24 h for the SPME, at the anesthesia concentrations evaluated (450-10

273 TP), the desorption of the analytes from the SPME devices in our setup is completely separated from t

274 tes were quantitatively transferred from the SPME to the DBDI source, and the use of an active capill

275 s are completely eliminated by inserting the SPME fiber directly into the MS.

276 s via synthesis and functionalization of the SPME coating.

277 The selectivity of the SPME method toward mRNA was enhanced by functionalizing

278 compensating for the loss of the drug to the SPME coating.

279 ng the increased porosity coating, while the SPME protocol on the tryptic digestion of a protein supp

280 The results obtained were compared to SPME-GC/MS analysis in which compounds were resolved by

281 28 and 71 days of ripening and subjected to SPME GC/MS analysis.

282 ted by loading the sample inside the in-tube SPME device (withdraw of sample via plunger), where extr

283 n of sample, revealing the developed in-tube SPME device as an ideal probe for forensic application,

284 (LC-MS/MS) or direct coupling of the in-tube SPME device to the MS.

285 The in-tube SPME device was shown to be very sensitive, with high to

286 The sensitivity of TV-SPME is nearly twice that of liquid injection for cotini

287 lts with those obtained by the commonly used SPME methodology, optimisation of SBSE achieved better r

288 Using SPME, 36 compounds were isolated in whole pressed 'Wonde

289 ical changes, and volatiles formation (using SPME-GC/MS) was investigated.

290 (VOC) were sampled from the headspace using SPME fibers.

291 ati) were characterised and identified using SPME GC-O, GC-PFPD and confirmed using GC-MS.

292 varieties grown in Egypt were profiled using SPME-GCMS coupled to multivariate data analysis to explo

293 determined using ICP-OES and volatiles using SPME-GC/MS.

294 indings demonstrate the potential of in vivo SPME as a tool of scientific and clinical interest capab

295 imally invasive, and easily executed in vivo SPME is now possible opening the door to near endless sa

296 The standard in vivo SPME protocol based on mass spectrometry is a very power

297 The in vivo SPME sampling approach has been demonstrated as capable

298 hed light into the implementation of in vivo SPME strategies in quantitative metabolomics studies of

299 and protein on the extraction of ctDNA with SPME are explored.

300 diagrams for custom components operated with SPME/DART/MS equipment are included.