ライフサイエンスコーパス: SPR

1 SPR at Study Day 210 was >97% in both arms.

2 SPR confirmed that the C antibody favors binding with fr

3 SPR confirmed the results from earlier electrochemical a

4 SPR is a popular label-free detection technology because

5 SPR method can become a valuable addition to analytical

6 SPR offers several advantages in terms of label free det

7 SPR revealed rapid and stable association of EpiSCs with

8 SPR sensors with different average surface densities of

9 SPR signals were enhanced based on a combination process

10 REST, SPR-3, SPR-4 and reduced excitation activate the longevity-asso

11 her surveillance radars to estimate over 50% SPR during spring and autumn through the Gulf of Mexico

12 e reliability of the response generated by a SPR sensor must be guaranteed, especially in substance d

13 A new strategy to describe a SPR-sensorgram is shown.

14 heoretical and experimental realization of a SPR based fiber optic nicotine sensor having coatings of

15 assays and ELISA feasibility; additionally, SPR imaging analysis of a supported membrane microarray

16 Real-time amplified SPR response is observed upon the introduction of nonlin

17 in a biomolecular layer on the surface of an SPR sensor results in significant SPR spectral shifts, a

18 or POC, this is the first report of using an SPR biosensor for measuring DBS samples.

19 n important mycotoxin, was captured using an SPR gold chip containing an antifouling layer and monocl

20 nstants with literature values and analogous SPR measurements indicates that this approach is applica

21 RI)-based label-free methods such as BLI and SPR is the requirement to tether one of the interaction

22 eptide-spot array screening, competition and SPR assays, high-resolution crystallography, and mutatio

23 flow in the SPR is linear and continuous and SPR enables real-time reading of mucin-bacterial bonds,

24 nding properties using NMR, SAXS, cryoEM and SPR.

25 s interpretation, co-immunoprecipitation and SPR experiments indicated that EBI3 binds IL-6.

26 Microarray and SPR assays of structurally defined HS oligosaccharides s

27 X-ray crystallography, HDX-MS and SPR analysis confirmed that the CDR regions of VHH6 inte

28 paves the way for further use of TG-SERS and SPR in EV studies.

29 Simulations and SPR experiments suggested that an Fn conformational chan

30 For this, we measured real-time full-angular SPR response curves for G(s), G(q), and G(i) signaling p

31 enzoic acid (4-MBA) modified gold (4-MBA/Au) SPR chip was developed first time for the detection of B

32 to highlight the specific role of available SPR-based sensing methods for early detection of AD biom

33 olic acid protein (FAP) using graphene-based SPR chips.

34 In addition, the nonlinear HCR based SPR biosensing methodology is extended to the detection

35 esearch avenue of SPR and fiber optics based SPR for chemical and biological sensing.

36 ggest the potential of this GO-peptide-based SPR chip detection method in clinical application.

37 ein, the major advantage of GO-peptide-based SPR sensors was their reduced nonspecific adsorption and

38 Besides, SPR lacks in the detection of various binding events, pa

39 on constants were determined using a Biacore SPR device (1:1 Langmuir binding model).

40 sation was comparable with that of a BIAcore SPR system, an expensive laboratory gold standard, with

41 ity molecular target, which was confirmed by SPR and crystallography.

42 es and proteins, which are not detectable by SPR alone.

43 86I (Kd(app) = 0.2-0.5 mum, as determined by SPR) compared with the lowest-affinity double-alanine pe

44 the detection limit of the attomole level by SPR imaging measurements for different miRNA concentrati

45 This was supported by SPR measurements that showed stronger liposome partition

46 CD80 ligands were synthesized and tested by SPR for affinity to human CD80 (hCD80) and displacement

47 d through pi-stacking on the graphene coated SPR chip and the FAP analyte in serum.

48 at our NanoBioAnalytical platform, combining SPR and AFM, is a suitable method for a sensitive, repro

49 nsitivity of 16 times that of a conventional SPR chip.

50 ed by up to 1.2 times that of a conventional SPR chip.

51 dvancing understanding of migration ecology, SPR will facilitate conservation through identification

52 An effective SPR nanosensor based on core-shell nanoparticles (Ag@AuN

53 for the discovery of novel, ligand-efficient SPR inhibitors.

54 Mainly, it focuses on newly emerged enhanced SPR biosensors towards high-throughput and ultrasensitiv

55 In addition, the fabricated SPR sensor showed good selectivity for the target analyt

56 e sex-peptide-receptor is absent in females (SPR-) have higher polyandry, and - as a result - weaker

57 FO-SPR has enabled sensitive sensing capabilities in biomed

58 FO-SPR probes were homogeneously functionalized with ZIF-8

59 paper, we describe the development of an FO-SPR immunoassay for the detection of autoantibodies in p

60 ay, driven by PCR-amplified DNAzymes, for FO-SPR-based sensitive and specific detection.

61 The two established MOF-FO-SPR sensors were then subjected to sensing experiments w

62 clusion, this paper demonstrates that our FO-SPR biosensor can be used as a true POC diagnostic tool

63 Finally, the POC FO-SPR immunoassay was validated by using matching serum an

64 The established point-of-care (POC) FO-SPR bioassay was also used to measure IFX in 100-fold di

65 a fiber-optic surface plasmon resonance (FO-SPR) biosensor for detection of IFX spiked in 100-fold d

66 ed fiber-optic surface plasmon resonance (FO-SPR) biosensor.

67 Fiber optic-surface plasmon resonance (FO-SPR) can overcome these limitations, but improved surfac

68 er optic based surface plasmon resonance (FO-SPR) sensors.

69 e, fiber optic surface plasmon resonance (FO-SPR) technique is presented as an alternative readout fo

70 ed to 4-5 h for a regular ELISA) make the FO-SPR immunoassay a powerful assay for routine diagnosis o

71 Finally, the FO-SPR immunoassay was validated using seven iTTP patient p

72 o solutions was directly monitored by the FO-SPR system.

73 h are required for compatibility with the FO-SPR system.

74 IFX concentrations determined with FO-SPR were compared to a clinically validated enzyme-linke

75 tion of anti-ADAMTS13 autoantibodies with FO-SPR.

76 Two types of analysis methods for SPR images are used to study the protein-antibody intera

77 d and applied a novel mathematical model for SPR data treatment that enables determination of kinetic

78 ortant sensitivity enhancement substrate for SPR.

79 st prominent label-free parameters: the full SPR curve angular and intensity shifts, we present how t

80 ped in situ click chemistry to functionalize SPR sensor chips.

81 In further SPR experiments, K(D) values between FH and C3b on a cus

82 3AV induced high SPR and there were no safety concerns.

83 ETO imprinted SPR nanosensor based on Ag@AuNPs-HBN nanocomposite was d

84 Finally, the imprinted SPR nanosensor was applied to the urine samples having h

85 shed between affinity constant determined in SPR and metal chelation capacity determined from UV-visi

86 ll-characterized by pronounced difference in SPR spectral band position (shifting up to 50nm).

87 ernity share is relatively more important in SPR- groups, where males gain additional paternity by ma

88 esolution and better surface localization in SPR imaging.

89 L-approach allow the creation of intelligent SPR sensors to give a safe, reliable, and auditable anal

90 aphy-multiangle light scattering (SEC-MALS), SPR-based biophysical analyses and microscale thermophor

91 imit of detection of peptide matrix modified SPR sensor was 0.62 ppb, and hence comparable to single-

92 Moreover, SPR principles, assay formats, and signal enhancement ar

93 ochemical, fluorescence-based, nanomonitors, SPR-based, and field-effect transistor biosensors for ea

94 Notably, SPR analysis indicated that constitution of WTA determin

95 Up to now, SPR has been poorly exploited for tau detection by immun

96 l free detection of miRNAs and advantages of SPR-based method was presented.

97 s implemented for a quantitative analysis of SPR under plane-wave illumination and a finite-differenc

98 Overall, our work extends the application of SPR beyond the realm of 1:1 stoichiometric ligand-recept

99 it provides an avenue for the application of SPR sensors for fast, label-free determination of the ne

100 Moreover, applications of SPR in the detection of pesticide, polycyclic aromatic h

101 nts made in the potential research avenue of SPR and fiber optics based SPR for chemical and biologic

102 sis techniques: the biosensing capability of SPR and the chemical identification power of high resolu

103 concepts and performance characteristics of SPR biosensor.

104 n simplifies the conventional combination of SPR and QCM and has the potential to be miniaturized for

105 nsor, determined here using a combination of SPR and X-ray photoelectron spectroscopy (XPS) measureme

106 surement principles based on (i) detuning of SPR as a result of the modification of the interfacial r

107 s) like gold (Au) NPs for the fabrication of SPR biosensor has shown remarkable impact both for ancho

108 intelligence features, the new generation of SPR-intelligent biosensors is qualifying to perform auto

109 (DOX))-treated cells show slow increases of SPR signals in the first 2 h due to the nucleus swelling

110 led to double-digit nanomolar inhibitors of SPR with excellent ligand efficiency.

111 ation methods can overcome the limitation of SPR methods for detection of small molecules, making it

112 y improve the sensitivity and selectivity of SPR sensor evidently.

113 The reported sensitivity of SPR to surface charge is especially important in the con

114 bel-based signal amplification strategies of SPR platforms including nanoparticle enhancement, supers

115 smon resonance (SPR) imaging measurements on SPR chips possessing an Au spot array modified with prob

116 igomerization that leads to stabilization on SPR surfaces.

117 city as compared to conventional fiber optic SPR sensor (detection limit: 391 CFU/mL, sensitivity: 0.

118 Orthogonal SPR, crystallography, and NMR experiments demonstrated t

119 The VP1 detection in the portable SPR biosensor had a detection limit of approximately 4.8

120 Furthermore, the prepared SPR nanosensor was examined in terms of stability, repea

121 Up to present, SPR application in stem cell biology and biomedical scie

122 econdary outcomes were seroprotection rates (SPR), defined as anti-HBs >10 mIU/mL and anti-HBs geomet

123 we introduce the stopover-to-passage ratio (SPR), the percentage of passage migrants that stop in an

124 sociated with pterin [sepiapterin reductase (SPR)] and carotenoid [beta-carotene oxygenase 2 (BCO2)]

125 Surface plasmon resonance (SPR) analysis confirmed that rHDL/Do facilitated microgl

126 sonance (NMR) and surface plasmon resonance (SPR) analysis.

127 By combining surface plasmon resonance (SPR) and electrolyte gated field-effect transistor (EG-F

128 e been studied by surface plasmon resonance (SPR) and fluorescence spectroscopy.

129 echniques such as surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC) can prov

130 ed on propagating surface plasmon resonance (SPR) and localized surface plasmon resonance (LSPR) have

131 crobalance (QCM), surface plasmon resonance (SPR) and X-ray photoelectron spectroscopy (XPS).

132 atheta(r)) in the surface plasmon resonance (SPR) angle.

133 Surface plasmon resonance (SPR) as one of the relatively novel and simple analytica

134 ymer is sensed, a surface plasmon resonance (SPR) assay using varied PG surface presentation was deve

135 tion systems like Surface Plasmon Resonance (SPR) assays, Impedance-based method, Quartz Crystal Micr

136 he characteristic surface plasmon resonance (SPR) band of Tyr-Au NPs was red-shifted to 596 and 616nm

137 he first assay is surface plasmon resonance (SPR) based and can quantitate both antibody binding to t

138 Surface plasmon resonance (SPR) based dopamine sensor is realized using the state-o

139 The Surface Plasmon resonance (SPR) based label-free detection of small targeted molecu

140 k, we developed a surface plasmon resonance (SPR) based method for investigating bacteria/mucins inte

141 id cost-effective surface plasmon resonance (SPR) based method for measuring the Rexocytosis for popu

142 Surface plasmon resonance (SPR) based sensing is an attractive approach for realizi

143 Surface plasmon resonance (SPR) based sensors allow the evaluation of aqueous and g

144 , and show unique surface plasmon resonance (SPR) behaviors.

145 Guided by a surface plasmon resonance (SPR) binding assay, we selected six hybridomas that prod

146 FIAs with C only, surface plasmon resonance (SPR) binding experiments on the immobilized control anti

147 e and enzyme-free surface plasmon resonance (SPR) biosensing strategy has been developed for highly s

148 teins employing a surface plasmon resonance (SPR) biosensor and heat shock protein 70 (Hsp70) that re

149 have presented a surface plasmon resonance (SPR) biosensor technique for the detection of anti-PEG a

150 determined using surface plasmon resonance (SPR) biosensor technology are 262 +/- 4 nM for iMVP/INT,

151 GO-peptide-based surface plasmon resonance (SPR) biosensor.

152 Surface plasmon resonance (SPR) biosensors are most commonly applied for real-time

153 Surface plasmon resonance (SPR) biosensors have become an important label-free opti

154 onstrating that a surface plasmon resonance (SPR) can be excited in this case.

155 IP biosensor with surface plasmon resonance (SPR) detection.

156 Herein, a surface plasmon resonance (SPR) enhanced DNA biosensor has been developed for real-

157 e a generation of surface plasmon resonance (SPR) for plasmonic sensing.

158 ay (SIA) based on surface plasmon resonance (SPR) for the rapid detection of Campylobacter jejuni was

159 that measured by surface plasmon resonance (SPR) for the same binding reaction.

160 hydrolysate using Surface Plasmon Resonance (SPR) for their antioxidant properties.

161 biosensors namely Surface Plasmon Resonance (SPR) has been extensively investigated for the detection

162 be used with most surface plasmon resonance (SPR) imaging instruments.

163 NA) detections by surface plasmon resonance (SPR) imaging measurements on SPR chips possessing an Au

164 nostructure-based surface plasmon resonance (SPR) imaging platform, comprising multiple aluminum nano

165 ified coupling of surface plasmon resonance (SPR) immuno-biosensing with ambient ionization mass spec

166 Surface plasmon resonance (SPR) immunosensor enhanced by biocatalyzed precipitation

167 lized fiber optic surface plasmon resonance (SPR) immunosensor has been reported for the sensitive de

168 Surface plasmon resonance (SPR) immunosensor using 4-mercaptobenzoic acid (4-MBA) m

169 Surface Plasmon Resonance (SPR) in combination with different amplification strateg

170 mission images of surface plasmon resonance (SPR) in metallic nanostructures.

171 uptake of EVs by surface plasmon resonance (SPR) in real-time.

172 oxide (GO)-coated Surface Plasmon Resonance (SPR) interfaces.

173 Surface Plasmon Resonance (SPR) is a powerful technique for studying 1:1 stoichiome

174 Surface plasmon resonance (SPR) is the current standard tool used for label-free ki

175 Surface plasmon resonance (SPR) measurements confirmed that mutations of these RBD

176 Surface plasmon resonance (SPR) measurements showed that polymer conjugation did no

177 perature gradient surface plasmon resonance (SPR) measurements to quantitatively evaluate how the sta

178 the potential of surface plasmon resonance (SPR) method coupled to atomic force microscopy (AFM) to

179 is literature the surface plasmon resonance (SPR) modeling of AuNPs was accurately captured toward pr

180 which include the surface plasmon resonance (SPR) of Au nanoparticles, low overpotential of Pt nanopa

181 y and affinity by surface plasmon resonance (SPR) of the four Cluster C proteins in NTHi.

182 Surface plasmon resonance (SPR) offers exceptional advantages such as label-free, i

183 s, the effects of surface plasmon resonance (SPR) on sensing as well as current state-of-the-art of e

184 ties of localized surface plasmon resonance (SPR) phenomenon to study non-covalent interactions not j

185 oin antibodies by surface plasmon resonance (SPR) revealed low nanomolar antiserum affinity for the k

186 ation of NP627 by surface plasmon resonance (SPR) revealed that PKCdeltaI and NP627 interact with eac

187 possible using a surface plasmon resonance (SPR) scattering technique.

188 Surface plasmon resonance (SPR) sensor as an example of portable, rapid, and smart

189 A Surface Plasmon Resonance (SPR) sensor chip consisting of four sensing arrays enabl

190 s fabricated on a surface plasmon resonance (SPR) sensor chip to enhance the sensitivity of detecting

191 ed ultrasensitive surface plasmon resonance (SPR) sensor in a checkerboard nanostructure on plastic s

192 Fiber optic surface plasmon resonance (SPR) sensor utilizing silver (Ag) and Ag-graphene oxide

193 Moreover, surface plasmon resonance (SPR) showed that longer chain of synthetic alpha(1-6)man

194 Surface plasmon resonance (SPR) spectroscopy is an advanced tool to measure binding

195 Using surface plasmon resonance (SPR) spectroscopy, we demonstrated that KRAS and Raf-1 p

196 at accumulates on surface plasmon resonance (SPR) surfaces coated with properdin, but SG7.AF binds wi

197 using a portable surface plasmon resonance (SPR) system.

198 angular-scanning surface plasmon resonance (SPR) technique is utilized for measuring label-free GPCR

199 trated the use of surface plasmon resonance (SPR) technology for the first time to characterize the c

200 were screened by surface plasmon resonance (SPR) to determine the binding dissociation constant (off

201 Combining surface plasmon resonance (SPR) with atomic force microscopy (AFM), here we studied

202 omes detection by surface plasmon resonance (SPR) with dual gold nanoparticle (AuNP)-assisted signal

203 al (fluorescence, Surface Plasmon Resonance (SPR)), microbial and DNA biosensors in detail.

204 The surface plasmon resonance (SPR), an optical biosensor, possessing various advantage

205 microscopy (AFM), surface plasmon resonance (SPR), and molecular simulations were used to investigate

206 Here, using surface plasmon resonance (SPR), antigen presentation assays, and X-ray crystallogr

207 nitoring (QCM-D), surface plasmon resonance (SPR), atomic force microscopy (AFM), and fluorescence mi

208 man spectroscopy, surface plasmon resonance (SPR), electrochemiluminescence and colorimetric readouts

209 rimetry (ITC) and surface plasmon resonance (SPR), respectively.

210 Using surface plasmon resonance (SPR), we found that IL-1RAcP also does not bind IL-36R w

211 With surface plasmon resonance (SPR), we present this diversified collection to collagen

212 or change, due to surface plasmon resonance (SPR), which occurs in about 30min of total assay time wh

213 -based biosensor, surface plasmon resonance (SPR)-based biosensor and artificial intelligence (AI) as

214 films for use in surface plasmon resonance (SPR)-based immunoaffinity biosensors.

215 Surface plasmon resonance (SPR)-biosensor experiments show that the drug can displa

216 ely accepted that surface plasmon resonance (SPR)-generated energetic electrons play an essential rol

217 R) was studied by surface plasmon resonance (SPR).

218 roscopy (EIS) and surface plasmon resonance (SPR).

219 ) was measured by Surface Plasmon Resonance (SPR).

220 nding through the surface plasmon resonance (SPR).

221 oscopy (EIS), and surface plasmon resonance (SPR).

222 ceptor FZD8 using surface plasmon resonance (SPR).

223 emonstrated using surface plasmon resonance (SPR).

224 h AP and AS using surface plasmon resonance (SPR).

225 e investigated by surface plasmon resonance (SPR).

226 rared (FT-IR) and surface plasmon resonance (SPR).

227 urther studied by surface plasmon resonance (SPR).

228 REST, SPR-3, SPR-4 and reduced excitation activate the longevi

229 Per our results, SPR has high potential in applications in least-interfer

230 eports the operation principles for reusable SPR biosensors utilizing nanoscale-specific electrostati

231 o construct a highly sensitive and selective SPR chip for folate biomarker sensing in serum.

232 be DNAs based on a miRNA-detection-selective SPR signal amplification method.

233 Using this highly sensitive SPR method, it was possible to sense the early stage of

234 The SIA-SPR method together with the culturing (plating) method

235 This SIA-SPR method showed excellent sensitivity for C. jejuni wi

236 face of an SPR sensor results in significant SPR spectral shifts, and we identify two major mechanism

237 ch other with high affinity and specificity, SPR kinetics revealed that NP627 disrupts caspase-3 bind

238 for the first time, the presence of a stable SPR signal recorded in soft matters.

239 a novel surface plasmon resonance technique (SPR) is developed and used, along with hepatocyte (with

240 The SPR partition data obtained for the antibody fragment F6

241 The SPR performance is consistent with that of previous repo

242 The SPR results also indicated that NP627 affects macromolec

243 The SPR sensor instrument was configured to run on low power

244 The SPR shift observed was assessed to 3.83 +/- 0.05 nm with

245 The SPR signal processing using integration area under the r

246 The SPR signals increased with the increase of the amount of

247 The SPR technique developed may be used for the future study

248 -specifically and dramatically amplified the SPR signals.

249 structures (metallic or not) may amplify the SPR signal and improve the limit of detection to the des

250 the electronic mechanism is dominant and the SPR wavelength shift is linearly proportional to the sur

251 as a gate electrode of the EG-FET and as the SPR active interface.

252 Conversely, the SPR responses obtained for vitamin D3 show that the inte

253 e of immune-reactive biochips and during the SPR analysis.

254 ECL of CdS NCs firstly evoked the SPR of AuNPs which in return amplified the CdS NCs ECL i

255 P/TNW, respectively, which benefits from the SPR-induced photoabsorption increment and charge separat

256 Furthermore, the SPR sensor could effectively detect the exosomes in 30%

257 binding of recombinant DEPTOR to mTOR in the SPR assay.

258 The fluid flow in the SPR is linear and continuous and SPR enables real-time r

259 es, causing a characteristic decrease in the SPR signal.

260 bioassay with the capability to increase the SPR signal of about 10(2) folds compared to direct detec

261 arge of a biomolecular system influences the SPR biosensor response.

262 Moreover, the SPR sensor had the capability to differentiate the exoso

263 omplete thermodynamic cycle to be 74 mum The SPR analysis also indicated that the IL-36R antagonist I

264 en two neighboring wavelength bands near the SPR wavelength, the signal-to-noise ratio for biosensing

265 With respect to the shifts of the SPR angles of the chips, the affinity immunoassay intera

266 ensor chip were below the sensitivity of the SPR apparatus.

267 the dynamic range (10(-3)-10(3)ng/ml) of the SPR biosensor.

268 g screening has identified the source of the SPR periodic signal to be direct cell contraction rather

269 rface was suppressed and regeneration of the SPR sensor was realized.

270 , resulting in a significant increase of the SPR signal.

271 the medium, resulting in rapid drops of the SPR signals.

272 t anti-rabbit IgG polyclonal antibody on the SPR sensor chip.

273 in which the fragments were presented on the SPR surface influenced the strength of PG recognition by

274 U), nonspecific adsorption of AuNPs onto the SPR chip surface was suppressed and regeneration of the

275 flowing factor B, factor D, and C3 over the SPR chip, we amplified C3b from ~20 to ~220 molecules.mu

276 hip to become four times as sensitive to the SPR angle shift and to have the lowest antibody detectio

277 ctric and ionic mechanisms contribute to the SPR wavelength shift.

278 spectra are recorded simultaneously with the SPR sensorgram, and the detected Raman bands provide che

279 the direct and label-free detection with the SPR technique and neutralized chimeric probe DNA can be

280 This SPR shift correlates remarkably well with biochemical es

281 Thus, SPR principles, assay formats, surface modification meth

282 e and attest to the quality of the real-time SPR responses so-called sensorgrams.

283 O-COOH chip, an Au/GO chip and a traditional SPR chip are 35.5m degrees , 9.128m degrees and 8.816m d

284 The platform has advantages over traditional SPR in terms of insensitivity of signal responses to pH

285 Transmission SPR measurements of free prostate specific antigen (f-PS

286 To address this problem, we use SPR spectroscopy correlated with surface enhanced Raman

287 We used SPR to monitor complement initiation occurring through a

288 cific cleft in the binding pocket, and using SPR competition assays, we observed that heme does not d

289 peptides were screened in hydrolysates using SPR and a correlation was established between affinity c

290 stics on molecular and cellular levels using SPR, ELISA, and flow cytometry.

291 lly evaluated (4.1 +/- 0.7 x 10(-4) M) using SPR by fitting data to a 1:1 Langmuir interaction model.

292 ing bacterial binding assays to mucins using SPR is feasible and has advantages over microtiter-based

293 lated from different epithelial sites, using SPR and microtiter-based binding assays.

294 tween technical replicates was smaller using SPR detection compared to the adenosine 5'-triphosphate

295 rug-target residence time was determined via SPR.

296 hitecture is a typical complex system, where SPR response is formed by the stochastic interactions wi

297 t using immobilized probe 1 and probe 2 with SPR which showed the applicability of this methodology a

298 chemically diverse inhibitors complexed with SPR, identifying relevant interactions and binding modes

299 ly protocol for Leishmaniasis diagnosis with SPR was used to verify this new feature.

300 e.g., refractive index and temperature) with SPR-based nanoprobes, although highly desirable, is chal