ライフサイエンスコーパス: ST segment depression

1 r systemic inflammation, blood pressure, and ST segment depression.

2 ring which the patient developed > or = 1-mm ST-segment depression.

3 elevation or bundle branch block, and 7% had ST-segment depression.

4 e, smoking status, diabetes, heart rate, and ST-segment depression.

5 ischemia, as shown by a decrease in maximal ST-segment depression (1.84+/-0.14 versus 1.63+/-0.13 mm

6 diographic abnormalities (13 of 15 rabbits), ST-segment depression (10 of 15 rabbits), and preventric

7 hest in the patients achieving <10 METs with ST-segment depression (14 of 70, 19.4%).

8 d self-reported symptoms and reduced maximal ST segment depression (-142 vs. -156 muV, p = 0.046) ove

9 0.83 mm, P=0.027), and time to resolution of ST-segment depression (229+/-30 versus 207+/-28 s, P=0.0

10 529 +/- 190 s, p = 0.002) and longer time to ST segment depression (530 +/- 215 vs. 419 +/- 205 s, p

11 ssion compared with patients without resting ST segment depression (71 +/- 6% vs. 42 +/- 4%) and spec

12 lysis compared with patients without resting ST segment depression (77 +/- 7% vs. 45 +/- 4%) and spec

13 chemia defined as the appearance of >=0.1-mV ST-segment depression 80 ms from the J-point on electroc

14 rdiovascular death risk for exercise-induced ST-segment depression (age-adjusted hazard ratio, 1.02;

15 AD, leaflet redundancy, and T-wave inversion/ST-segment depression (all p < 0.0001) but not with mitr

16 end-systolic diameter, and T-wave inversion/ST-segment depression (all p <= 0.001).

17 rval, a Q wave, abnormal QRS axis deviation, ST segment depression and a pathologic T wave more frequ

18 ng, left ventricular cavity dilation, marked ST segment depression and blood pressure decrease indica

19 t in a large cohort of patients with resting ST segment depression and no prior myocardial infarction

20 increased significantly before the onset of ST segment depression and persisted throughout the ische

21 tes, hypertension, smoking history, baseline ST segment depression and previous coronary artery bypas

22 he subgroup (n = 29) with dobutamine-induced ST-segment depression and abnormal SPECT imaging, the pr

23 were independently predictive of mortality (ST-segment depression and age > or = 65 years).

24 croV of additional horizontal or downsloping ST-segment depression and by an ST-segment/heart rate (S

25 nts decreases heart rate variability, causes ST-segment depression and endothelial dysfunction, incre

26 prolongation of the time to exercise-induced ST-segment depression and resolution of myocardial perfu

27 axis, Sokolow-Lyon and Cornell voltages, and ST-segment depression and slope.

28 was to investigate the relationship between ST-segment depression and the rate-pressure product (RPP

29 ficacy criteria were changes in time to 1-mm ST-segment depression and time to limiting angina during

30 Time to onset of > or = 1-mm ST-segment depression and time to onset of angina were s

31 iables--diabetes, hypertension, magnitude of ST segment depression, and exercise rate-pressure produc

32 eline characteristics, number of episodes of ST-segment depression, and baseline serum cholesterol le

33 ST-segment depression, appearing in unfiltered bipolar e

34 lusion of the artery and are associated with ST-segment depressions (approximately 31%), T-wave inver

35 Chest pain and ST segment depression are extremely common findings in p

36 ulated for patients with and without resting ST segment depression as determined by visual or compute

37 When QTD of > 60 ms was added to ST-segment depression as a condition for positive test,

38 Familial history of sudden cardiac death and ST-segment depression associated with PTWI were predicti

39 mg/h) significantly reduced the magnitude of ST segment depression at angina onset during ETT compare

40 was used to group patients as follows: 1) no ST segment depression at any time (control group); 2) ST

41 ro V of additional horizontal or downsloping ST segment depression at peak exercise.

42 was 61 +/- 10 years; 97% were male; 38% had ST segment depression at study entry; 30% had an anterio

43 ercise duration at peak and in times to 1 mm ST-segment depression at trough and peak and to angina a

44 ere exercise duration and time to > or =1-mm ST-segment depression, average daily anginal attack coun

45 There were two patients with ST-segment depression before and one after caffeine inta

46 ted risk > or =20%, failure to reach THR and ST-segment depression both more than doubled the risk of

47 ents with CAD with profound exercise-induced ST segment depression but good ETT duration is an approp

48 The classification of resting ST segment depression by method of analysis (visual vs.

49 dicators of ischemia during the speech test (ST-segment depression, chest pain) did not predict death

50 Duke score, including ST-segment depression, chest pain, and exercise capacity

51 on results from the exercise test, including ST-segment depression, chest pain, and exercise duration

52 31%), T-wave inversions (approximately 12%), ST-segment depressions combined with T-wave inversions (

53 test increased in 349 patients with resting ST segment depression compared with patients without res

54 At 12-min exercise, the amount of ST-segment depression compared with placebo and controll

55 icant reduction in the number of episodes of ST-segment depression compared with the placebo group.

56 ographic criteria, including left precordial ST segment depression, complete atrioventricular heart b

57 es performance of the simple and HR-adjusted ST-segment depression criteria for the identification of

58 levation criteria and those only meeting the ST-segment depression criteria.

59 test increased in 206 patients with resting ST segment depression determined by visual ECG analysis

60 ST-segment depression did not predict mortality.

61 However, ST-segment depression did occur in two patients requirin

62 419 +/- 205 s, p = 0.0001) and less frequent ST segment depression during ambulatory monitoring (9% v

63 Patients with stable symptoms but profound ST segment depression during ETT are often referred for

64 comes in patients with profound (> or =2 mm) ST segment depression during exercise treadmill testing

65 utine daily activities was best predicted by ST segment depression during mental or bicycle exercise

66 tal or exercise stress is more predictive of ST segment depression during routine daily activities th

67 The presence of ST segment depression during routine daily activities wa

68 and systolic blood pressure changes at 1-mm ST segment depression during treadmill exercise testing

69 In fact, asymptomatic (or silent) ST-segment depression during ambulatory electrocardiogra

70 ics have a higher prevalence of asymptomatic ST-segment depression during exercise treadmill testing

71 ients with coronary artery disease (CAD) and ST-segment depression during exercise were studied befor

72 he duration of exercise at the onset of 1-mm ST-segment depression during exercise, also remained unc

73 Eleven (15%) of 71 patients had ischemic ST-segment depression during exercise, whereas 27 patien

74 d 63% (P<.01), respectively, for > or = 1 mm ST-segment depression during stress.

75 rcentages of patients with only asymptomatic ST-segment depression during the 48-hour AECG were simil

76 Among asymptomatic men, ST-segment depression, failure to reach THR, and exercis

77 Adjustment of ST-segment depression for the change in HR with exercise

78 dex was calculated by dividing the change in ST segment depression from rest to peak exercise by the

79 rogen levels and an increase in time to 1-mm ST-segment depression from (mean+/-SEM) 309+/-27 seconds

80 ess imaging procedure for patients with rest ST-segment depression greater than 1 mm, complete left b

81 exercise electrocardiography was defined by ST segment depression > 0.1 mV, ischemia by exercise ech

82 ST segment depression > or = 1 mm was more common with e

83 (reversible left ventricular dysfunction or ST segment depression > or = 1 mm) developed in 106 of 1

84 ssociated with a 1.50-fold increased risk of ST-segment depression > or =0.1 mm (95% CI, 1.19 to 1.89

85 s of angina, and time to ischemic threshold (ST-segment depression > or =1 mm from baseline) during e

86 d relative to 3 exercise test variables: (1) ST-segment depression > or =1 mm, (2) failure to achieve

87 >/= 8%; and/or 3) horizontal or downsloping ST-segment depression >/= 1 mm in 2 or more leads lastin

88 h exercise-induced horizontal or downsloping ST-segment depression >/=1 mm, and 38 subjects (age, 77.

89 ST-segment depression >/=50 microV (n = 127) and CRP >7.

90 The presence of either major ST segment depression (>2 mm) or elevation on the admiss

91 Importantly, the time to ST-segment depression (>/=1 mm) also increased from 327+

92 03), pharmacologic test (HR: 1.63, P = .01), ST-segment depression (>=1 mm) (HR: 2.02, P < .001), myo

93 Heart rate adjustment of the magnitude of ST segment depression has been proposed as an alternativ

94 fixed magnitude of horizontal or downsloping ST segment depression has demonstrated only limited diag

95 ge and Framingham CHD risk score, among men, ST-segment depression (hazard ratio [HR], 1.88; 95% CI,

96 dered as a continuous variable and age, sex, ST-segment depression, heart failure, previous revascula

97 ncluding younger age of onset, more frequent ST-segment depression, higher prevalence of neurologic d

98 e recovery, achieving target heart rate, and ST-segment depression (HR: 1.68; 95% CI: 1.09-2.60; P =

99 le heart rate adjustment of the magnitude of ST segment depression improves the prediction of death f

100 nd heart rate changes related to episodes of ST segment depression in 17 patients with stable coronar

101 ST segment depression in leads other than those showing

102 ST segment depression in response to mental or exercise

103 Consideration of ST-segment depression in addition to elevation increased

104 effects of sub-endocardial ischaemia on the ST-segment depression in ECG to patterns of transmural a

105 onitoring occurs more often than symptomatic ST-segment depression in patients with coronary artery d

106 0.14 versus 1.63+/-0.13 mm, P=0.011), sum of ST-segment depressions in 12 leads (7.64+/-1.01 versus 6

107 er-protocol population (n=257), time to 1-mm ST-segment depression increased in the 5 and 10 mg BID g

108 Time to > or =1-mm ST-segment depression increased significantly from basel

109 ST-segment depression is associated with increased expos

110 Whether exercise-induced ST-segment depression <1 mm is an independent predictor

111 The risk of pollution-associated ST-segment depression may be greatest in those with myoc

112 ents reaching > or =10 METs without exercise ST-segment depression, none had > or =10% LV ischemia.

113 left ventricular cavity dilation and marked ST segment depression, occur more often with exercise th

114 Transient ST-segment depression occurred in 1 patient, and the rig

115 At a matched specificity of 96%, ST-segment depression of > 160 microV identified CAD wit

116 ved the sensitivity of each method: adjusted ST-segment depression of > 176 had a sensitivity of 87%

117 th much higher biomarker thresholds, (2) new ST-segment depression of >=1 mm for the primary and >=0.

118 Neither the number of Q waves, residual ST-segment depression of >or=0.5 mm or elevation of >or=

119 ing was defined as horizontal or downsloping ST-segment depression of 1 mm (0.1 mV) or more for 1 min

120 th much higher biomarker thresholds, (2) new ST-segment depression of 1 mm for the primary and 0.5 mm

121 % or more; and/or horizontal or down-sloping ST-segment depression of 1 mm or more in 2 or more leads

122 (in the same direction as) the QRS complex; ST-segment depression of 1 mm or more in lead V1, V2, or

123 or = 4 ischemic episodes or > or = 20 min of ST segment depression on 72-h electrocardiogram were ran

124 total exercise time, frequency of angina and ST segment depression on exercise.

125 final multivariate model included older age, ST segment depression on presentation, history of compli

126 ssess the effect of heart rate adjustment of ST segment depression on risk stratification for the pre

127 tudy is to demonstrate the effect of resting ST segment depression on the diagnostic characteristics

128 ous studies evaluating the effect of resting ST segment depression on the diagnostic characteristics

129 or of AECG abnormalities was the presence of ST segment depression on the initial exercise treadmill

130 1 and 327 mg/dL, and at least one episode of ST-segment depression on ambulatory ECG monitoring.

131 Of the ARCA patients, 2 had inferior ST-segment depression on EST; subsequently, 1 had normal

132 ss echocardiography (P = 0.05), magnitude of ST-segment depression on ETT (P = 0.004), and peak metab

133 ated initial serum cardiac biomarker levels, ST-segment depression on presenting electrocardiogram, a

134 Time to 1-mm ST-segment depression on treadmill exercise testing and

135 uggestive of myocardial ischemia, defined as ST segment depression or elevation of >/=1 mm in two con

136 positive exercise stress tests (> or = 1 mm ST-segment depression or reversible perfusion defects) a

137 1.02 per 1 mg, P = 0.0001), and presence of ST-segment depression (OR = 2.59, P = 0.007 and OR = 2.3

138 Such patients represent a high-risk (ST-segment depression) or low-risk (normal or nonspecifi

139 greater than the 87% sensitivity of adjusted ST-segment depression (P < .0001).

140 after nitroglycerin administration with less ST-segment depression (P=0.003) and therefore myocardial

141 gment elevation (simultaneous group); and 3) ST segment depression persisting after ST segment elevat

142 a positive troponin at baseline, diabetes or ST-segment depression, recurrent angina, prior aspirin u

143 Blinded analysis of ST segment depression resolution patterns was used to gr

144 We hypothesized that the timing of ST segment depression resolution relative to ST segment

145 t depression at any time (control group); 2) ST segment depression resolving simultaneously with ST s

146 Mean exercise duration to 1-mm ST-segment depression significantly increased in each gr

147 most useful electrocardiogram findings were ST-segment depression (specificity, 95%; LR, 5.3 [95% CI

148 c relationship between baseline quantitative ST-segment depression (ST) and cardiac troponin T (cTnT)

149 he treating provider to identify significant ST-segment depressions, ST-segment elevations, or T-wave

150 ST segment depression (STD) >/=50 micro V and rate-corre

151 protein (CRP) and electrocardiographic (ECG) ST-segment depression (STD) have additive utility for pr

152 nges in T-wave polarity, > or =1 mm STE, and ST-segment depression (STD) were 22, 24, 29, and 35 s, r

153 arction (AMI) and the application of similar ST-segment depression (STEMI-equivalent) criteria with c

154 ECG changes were defined as Q waves, ST-segment depression, T-wave changes, ventricular condu

155 assigned at admission-ST-segment elevation, ST-segment depression, T-wave inversion, or the presence

156 minutes, P < .01), and the maximum depth of ST-segment depression tended to be less in the diabetic

157 imultaneous versus independent resolution of ST segment depression that occurs concomitant with ST se

158 azine produced a dose-dependent reduction in ST-segment depression that became more marked as exercis

159 agnostic value of adjusting the magnitude of ST-segment depression, the ST-segment (ST)/HR index, and

160 of Ad5FGF-4 on total ETT time, time to 1 mm ST-segment depression, time to angina, and Canadian Card

161 rt the use of heart rate-adjusted indexes of ST segment depression to improve the predictive value of

162 nse and intensification of minor preexercise ST-segment depression to levels > or =1 mm independently

163 coronary artery disease and exercise-induced ST-segment depression underwent assessment of forearm en

164 mental or bicycle exercise stress, although ST segment depression was rare during mental stress.

165 se, achieving > or =10 METs with no ischemic ST-segment depression was associated with a 0% prevalenc

166 Exercise-induced ST-segment depression was associated with increased IMT

167 ST-segment depression was completely resolved in 13 of 2

168 Time to > or =1 mm ST-segment depression was increased with fasudil at both

169 ST-segment depression was more prevalent in patients wit

170 Exercise-induced ST-segment depression was present in all patients, but t

171 The RPP and ST-segment depression were assessed before starting exer

172 ymptoms, but abnormal lactate metabolism and ST-segment depression were unaffected after 10 min.

173 antly decreased for 20 min after recovery of ST-segment depression when events were triggered by high

174 reases exercise duration and reduces maximal ST-segment depression while exerting minimal effects on

175 years) with known stable CAD and > or =2 mm ST segment depression who are performing ETT according t

176 by heart rate adjustment of exercise-induced ST-segment depression will benefit from therapy aimed at

177 ck, or left-axis deviation) or exercise ECG (ST-segment depression with exercise, chronotropic incomp