ライフサイエンスコーパス: TAO

1 TAO and similar SHAM-sensitive alternative oxidases (AOX

2 TAO is a diiron protein that transfers electrons from ub

3 TAO is most prevalent in hyperthyroid patients with Grav

4 TAO is present at a reduced level in the procyclic form

5 TAO kinases are activated acutely by ionizing radiation,

6 osols collected in Cayenne, French Guiana, a TAO coastal site located at the northeastern edge of the

7 To learn more about TAO/KIN-18 function, we studied how expression of consti

8 Thousand and one amino acid (TAO) kinases are Ste20p-related MAP kinase kinase kinase

9 itude, and latency, was also evaluated among TAO patients.

10 ssel densities (onh-wiVD and rpc-wiVD) among TAO patients.

11 tion by the ATM protein kinase in cells; and TAO and p38 activation is compromised in cells from a pa

12 d-type and competitive inhibitor for TGK and TAO, respectively.

13 nase mutants, we found that MEKs 3 and 6 and TAOs were required for p38 activation by carbachol or th

14 components makes the formulation astaxanthin-TAO appealing for the food ingredients/additives industr

15 asurements at the Tropical Ocean Atmosphere (TAO) moorings are used to characterize and quantify the

16 The thymol:oleic acid DES (TAO) could preserve astaxanthin content after prolonged

17 the inclusion criteria, 740 (8.8%) developed TAO (mean follow-up, 374 days since initial GD diagnosis

18 ors that may increase the risk of developing TAO among patients with GD.

19 s used to determine the hazard of developing TAO among persons with newly diagnosed GD, with adjustme

20 d by the US Food and Drug Administration for TAO.

21 s associated with a 74% decreased hazard for TAO (adjusted HR, 0.26 [95% CI, 0.12-0.51]) compared wit

22 iated with substantially reduced hazards for TAO among patients with GD, preventive measures for this

23 The new susceptibility region for TAO at 16q12 harbors variants that correlate with the ex

24 tor might represent a therapeutic target for TAO.

25 the growth medium produces a non-functional TAO.

26 In TAO, CD34(+) fibrocytes, putatively derived from bone ma

27 d the expression of IL-6, IL-8, and MCP-1 in TAO fibroblasts but failed to do so in control cultures.

28 blasts diffusely in the body is causative in TAO and pretibial myxedema with even increased urinary s

29 ise a large subset of orbital fibroblasts in TAO.

30 could be further upregulated by IFN-gamma in TAO and control fibroblasts.

31 hyaluronan accumulation and inflammation in TAO derive from enhanced biosynthetic activities of orbi

32 gating the alterations of OCTA parameters in TAO patients was conducted.

33 te the complexity of choroidal remodeling in TAO and emphasize the multifactorial nature of its patho

34 r the natural course of tissue remodeling in TAO.

35 n, potentially governing immune responses in TAO.

36 hid fecundity was decreased significantly in TAO plants compared with other lines.

37 Early reports suggested that in TAO, both Tg and TSHR become overexpressed in orbital ti

38 tinct loci explained 6.0% of the variance in TAO.

39 ced MCP-1, IL-6, and IL-8 more vigorously in TAO-derived fibroblasts.

40 elpful in distinguishing active and inactive TAO patients, as well as differentiation of patients wit

41 VI were significantly higher in the inactive TAO group compared to healthy controls.

42 ncluded 50 eyes of 37 patients with inactive TAO (mean +/- standard deviation (SD) age: 47 +/- 11 yea

43 SFCT and CVI between patients with inactive TAO and age- and sex-matched normal individuals.

44 tes and uncovered a pair of protein kinases (TAO and STK25) that cooperate to maintain muscle-specifi

45 ) plants that have either high (PAO) or low (TAO) ascorbate oxidase (AO) activities relative to the w

46 and truncated fragments of dominant negative TAOs inhibit the activation of p38 by DNA damage.

47 through the Western Tropical Atlantic Ocean (TAO) between 15 N and 23 S.

48 he Amazon Basin and Tropical Atlantic Ocean (TAO), leading to sequestration of carbon dioxide.

49 onserved EXXH motif abolished the ability of TAO to complement the heme-deficient Escherichia coli st

50 t of ortho-phenanthroline on the activity of TAO was completely alleviated by the addition of iron in

51 ce of iron are essential for the activity of TAO.

52 ests that iron is needed for the activity of TAO.

53 of some OCTA measures for early detection of TAO with high sensitivity and specificity in addition to

54 xygenase 2 inhibitors and the development of TAO.

55 een applied to evaluate the effectiveness of TAO treatment approaches, including systemic corticoster

56 needed to elucidate the etiopathogenesis of TAO in TRAb-negative patients.

57 Eyes of TAO patients with DON showed delayed P100 latencies, dec

58 d T2 relaxation indicating an active form of TAO.

59 The inhibition of TAO by salicylhydroxamic acid (SHAM) or ascofuranone is

60 Inhibition of TAO expression by siRNA also decreases p38 activation by

61 Manifestations of TAO measured by hazard ratios (HRs) with 95% CIs.

62 entify those who developed manifestations of TAO.

63 n-binding residues within the EXXH motifs of TAO abolished the ability to confer SHAM-sensitive respi

64 in understanding the site-specific nature of TAO and the development of specific therapies.

65 The restrictive ophthalmopathy of TAO may be associated with more sustained ocular hyperte

66 n to preventing the irreversible outcomes of TAO.

67 dings may be relevant to the pathogenesis of TAO and provide insights into previously unrecognized, p

68 roidal vasculature during inactive phases of TAO by assessing choroidal vascularity index (CVI) and s

69 vitro; radiation induces phosphorylation of TAO on a consensus site for phosphorylation by the ATM p

70 ysis of 9 genome-wide association studies of TAO (total of 5462 asthmatic patients with a broad range

71 levels of IGF-1R and TSHR on the surfaces of TAO and control orbital fibroblasts and thyrocytes and e

72 Several new studies address the therapy of TAO, ranging from retrobulbar to oral to intravenous glu

73 To explore events downstream of TAOs, the effects of TAO2 on ternary complex factors (TC

74 contrast, IGF-1R levels are 3-fold higher on TAO vs control fibroblasts.

75 forms of Trypanosoma brucei depend solely on TAO for respiration.

76 els are 11-fold higher on thyrocytes than on TAO or control fibroblasts.

77 with ELTS exposure on time-to-asthma onset (TAO) in childhood.

78 riants associated with time to asthma onset (TAO).

79 Thyroid-associated ophthalmopathy (TAO) is a common and debilitating manifestation of Grave

80 Thyroid associated ophthalmopathy (TAO) is a common autoimmune condition affecting orbital

81 Thyroid-associated ophthalmopathy (TAO) represents a disfiguring and potentially blinding a

82 enesis of thyroid-associated ophthalmopathy (TAO), an autoimmune component of Graves disease.

83 Thyroid-associated ophthalmopathy (TAO), an autoimmune component of Graves' disease, is ass

84 enesis of thyroid-associated ophthalmopathy (TAO), the orbital manifestation of GD, remains uncertain

85 enesis of thyroid-associated ophthalmopathy (TAO).

86 nked with thyroid-associated ophthalmopathy (TAO).

87 known as thyroid-associated ophthalmopathy (TAO).

88 orbit to thyroid-associated ophthalmopathy (TAO).

89 re severe thyroid-associated ophthalmopathy (TAO).

90 Thyroid-associated orbitopathy (TAO) constitutes an immune-mediated inflammation of the

91 blindness in thyroid associated orbitopathy (TAO).

92 The German Therapy Allergen Ordinance (TAO) triggered an ongoing upheaval in the market for hou

93 (TGK) and trypanosomal alternative oxidase (TAO) is considered a validated strategy toward the devel

94 Trypanosome alternative oxidase (TAO) is the cytochrome-independent terminal oxidase of t

95 se known as trypanosome alternative oxidase (TAO).

96 telangiectasia mutated (ATM) phosphorylates TAOs in vitro; radiation induces phosphorylation of TAO

97 tion with ascofuranone (AF), the most potent TAO inhibitor.

98 organisms but not in mammals, thus rendering TAO an important chemotherapeutic target for African try

99 who developed a severe unilateral left-sided TAO.

100 sulfonic acids (PFSAs) only in the Southern TAO.

101 Among the identified MST3 substrates, TAO kinases regulate dendritic filopodia and spine devel

102 These findings indicate that TAO kinases are regulators of p38-mediated responses to

103 Taken together, these studies suggest that TAO protein kinases relay signals from carbachol through

104 These results suggest that TAO proteins lie in stress-sensitive kinase cascades and

105 The TAO (for thousand-and-one amino acids) protein kinases a

106 The TAO and TAP TAVR groups were similar in terms of device

107 The TAO approach, compared with TAP TAVR, was associated wit

108 The TAO trial (Treatment of Acute Coronary Syndrome With Ota

109 The TAO trial (Treatment of Acute Coronary Syndrome With Ota

110 nity (SSS) at 140 W along the equator at the TAO mooring since late May 2020.

111 n CVI or SFCT and clinical parameters in the TAO group (p > 0.05).

112 FCT and CVI were significantly higher in the TAO group compared to the control group (409.5 +/- 152.7

113 nocyte lineage cells, reside uniquely in the TAO orbit, where they masquerade as CD34(+) orbital fibr

114 abolism, were increased significantly in the TAO plants in response to aphid perception relative to o

115 the lines, the effect being the least in the TAO plants.

116 ning PFAS concentrations and profiles in the TAO.

117 ilable after the scheduled completion of the TAO procedure in 2026.

118 Here we show that the TAO kinases mediate the activation of p38 in response to

119 entrations) varied with depth throughout the TAO latitudinal sectors (North, Equator, South Atlantic,

120 portant source of soluble P than dust to the TAO and oceans in the Southern Hemisphere and may be mor

121 In this study, we use the TAO in situ measurements and the coincident VIIRS Chl-a

122 TAVR via the TAO approach is technically feasible, seems to be associ

123 Alternative oxidases similar to TAO have been found in a wide variety of organisms but n

124 l feasibility and safety of the transaortic (TAO) transcatheter aortic valve replacement (TAVR) appro

125 he expression level of mutated and wild type TAO (35 kDa) remained unaltered.

126 5% of the control cells containing wild type TAO.

127 inoperable, severe aortic stenosis underwent TAO TAVR in our institution.

128 the predominant PFASs present in the Western TAO.

129 Cells in which TAO kinases have been knocked down are less capable of e

130 We detected 5 regions associated with TAO at the genome-wide significant level (P < 5 x 10(-8)

131 are far more frequent in vivo in donors with TAO compared with healthy subjects.

132 al implications in managing individuals with TAO.

133 ned with informed consent from patients with TAO and from patients undergoing surgery for other nonin

134 that orbital fibroblasts from patients with TAO expressed elevated levels of CD40.

135 Patients with TAO in the course of HT need a careful and continued int

136 ination of orbital tissue from patients with TAO reveals similar colocalization to cell membranes.

137 nical response systemically in patients with TAO, potentially by restoring immune tolerance.

138 ting fibrocytes collected from patients with TAO, prior to and following teprotumumab treatment in vi

139 cytes is markedly increased in patients with TAO, suggesting that this receptor might represent a the

140 expression in fibroblasts from patients with TAO.