ライフサイエンスコーパス: TEWL

1 TEWL and FES demonstrated a significant difference betwe

2 TEWL could be used for stratifying infants in the first

3 TEWL measurements obtained at the time of the second imm

4 TEWL presents a monitoring modality that may predict foo

5 TEWL was measured 2 ways in 2 separate groups.

6 TEWL was measured on unaffected forearm skin.

7 The inverse of TEWL (1/TEWL) and removed SC thickness yielded a highly linear c

8 children with FA at 2 years of age had day 2 TEWL in the upper quartile.

9 Lowest quartile day 2 TEWL was protective against AD at 12 months.

10 itis (AD), infants with upper-quartile day 2 TEWL were 3.5 times more likely to have FA at 2 years th

11 anaphylaxis onset.CONCLUSIONSDuring OFCs, a TEWL rise anticipated a positive clinical challenge.

12 Although TEWL was normal in the basal state, following disruption

13 inhibition of FLG and LOR was recovered, and TEWL was decreased in organotypic skin transfected with

14 skin showed a significant EIS reduction and TEWL increase compared to untreated skin, with a relativ

15 of accurate, long-term measurement of SH and TEWL.

16 ; impaired skin barrier function, defined as TEWL in the upper quartile (>9.4 g/m(2) /h), and allerge

17 Attenuated TEWL correlated with decreased expression of the pro-inf

18 e barrier formation is well characterized by TEWL assay.

19 The results show that capacitance, TEWL, and absorption-desorption rates had larger values

20 Non-invasive point-of-care TEWL measurements were obtained, from closed wound-site

21 ct was independent of FLG mutation carriage, TEWL, and AD phenotype (flexural vs. non-flexural).

22 ds leads to the hypothesis that post-closure TEWL at the site of wound healing is a reliable biomarke

23 tion was found between the V0 (post-closure) TEWL score and the odds of wound recurrence, both in uni

24 In contrast, TEWL changed little as the outer SC layers were stripped

25 sence of MyD88 alleviated disease (decreased TEWL, skin thickness, proinflammatory cytokines), wherea

26 an experimental model of atopic dermatitis, TEWL, allergic sensitization, and epidermal thickness we

27 ce for association of this SNP with elevated TEWL also.

28 First, TEWL was measured using static, discrete measurements.

29 istically significant anterior cubital fossa TEWL values at 1, 6, and 12 months of age compared to th

30 s, and at age 3 months either lung function, TEWL, eczema, and/or FLG mutations.

31 <0.25, and skin barrier impairment as a high TEWL >9.50 g/m(2) /h.

32 Eczema, dry skin, and high TEWL at 3 months increased the risk of sensitization at

33 Eczema, dry skin, and high TEWL at 3 months predicted allergic sensitization at 6 m

34 sensitivity and 57.3% specificity; and high TEWL with 61.7% sensitivity and 78.1% specificity.

35 High-TEWL group showed increased zinc reflectance at 8-24 um

36 ared to NC skin (both P < 0.001), and higher TEWL and pH compared to CSU lesions.

37 LG, S100A8 and S100A9 expression, total IgE, TEWL and AD severity.

38 Post-MN changes in TEWL and impedance were significant in all groups (p < 0

39 treatment provided a significant decrease in TEWL in AD lesions, lowering it almost to the levels see

40 io chi-square tests to assess differences in TEWL at visit 0 (V0) between the closed wound site and r

41 was more pronounced by MRSA and resulted in TEWL increase in organotypic skin.

42 was stopping OFC based on a 1 g/m2/h rise in TEWL plus 1 objective allergic symptom observed by the p

43 us monitoring detected a significant rise in TEWL that presaged positive OFCs, but no rise was seen i

44 Kif3a(K14Delta/Delta) mice have increased TEWL, disrupted junctional proteins, and increased susce

45 expression in the skin, along with increased TEWL, epidermal thickness, and skin inflammation, all of

46 PEP) children had higher median non-lesional TEWL (16.9 g/m(2) /h) and IgE (90 kU/L) compared with SP

47 laggrin (FLG) and transepidermal water loss (TEWL) (assesses skin barrier integrity), S100A8 and S100

48 The lip skin transepidermal water loss (TEWL) and capacitance of CC patients were compared with

49 using UPLC-MS/MS, transepidermal water loss (TEWL) and epidermal pH.

50 skin resistance, transepidermal water loss (TEWL) and Fourier transform infrared (FTIR) spectroscopi

51 Transepidermal water loss (TEWL) and levels of epidermal barrier proteins were eval

52 quantified using transepidermal water loss (TEWL) and were correlated with the immune responses.

53 ry skin, and high transepidermal water loss (TEWL) at 3 months were associated with allergic sensitiz

54 oppler imaging, a transepidermal water loss (TEWL) device and a skin thermometer in a 28 h session.

55 ent of lipids and transepidermal water loss (TEWL) in lesional and non-lesional skin of adults and ad

56 ed with increased transepidermal water loss (TEWL) in risk allele carriers.

57 Transepidermal water loss (TEWL) is a measure of skin barrier function with emergin

58 ydration (SH) and transepidermal water loss (TEWL) is vital for diagnosing skin conditions and identi

59 birth cohort had transepidermal water loss (TEWL) measured in the early newborn period and at 2 and

60 Transepidermal water loss (TEWL) measurement provides a potential solution to detec

61 roscopy (EIS) and transepidermal water loss (TEWL) measurements after the 4 h of treatments with dete

62 nd 'non-stinger'; transepidermal water loss (TEWL) measurements; and sensitivity self-assessments: 's

63 Transepidermal water loss (TEWL) measures were collected at 12 months from a subset

64 ence by measuring transepidermal water loss (TEWL) post-closure at the site of wound repair.

65 ther increases in transepidermal water loss (TEWL) predate the development of clinical AD.

66 icantly increased transepidermal water loss (TEWL) was found in MRSA-colonized AD skin.

67 rm; impedance and transepidermal water loss (TEWL) were measured at baseline and post-MN to confirm m

68 EI and transepidermal water loss (TEWL) were measured before and after the application.

69 EIS and transepidermal water loss (TEWL) were measured in lesional and non-lesional skin.

70 ts of the rate of transepidermal water loss (TEWL) were recorded sequentially in vivo in human subjec

71 RCM, transepidermal water loss (TEWL), and fluorescence excitation spectroscopy (FES) we

72 rrier function by transepidermal water loss (TEWL), eczema, and filaggrin (FLG) mutations in infancy

73 ux across the SC, transepidermal water loss (TEWL), in six women, in vivo.

74 ring capacitance, transepidermal water loss (TEWL), rates of absorption-desorption as well as Raman s

75 nb3a-null mice on transepidermal water loss (TEWL), sensitization, and inflammation.

76 rmatitis (AD) and transepidermal water loss (TEWL).

77 ssed by measuring transepidermal water loss (TEWL).

78 4, P=0.0004) with transepidermal water loss (TEWL).

79 ity barrier using transepidermal water loss (TEWL).

80 pruritus ADQ, and transepidermal water loss/TEWL) with immune and barrier mRNAs in lesional and/or n

81 A study coordinator measured TEWL throughout the OFC and had no input on the OFC cond

82 An upper quartile 2 month TEWL was also strongly predictive of AD at 12 months (ar

83 In this observational study, the analysis of TEWL at the anterior cubital fossa area occurred prior t

84 At the same time, an increase of TEWL was observed, with a significant negative correlati

85 The inverse of TEWL (1/TEWL) and removed SC thickness yielded a highly

86 Measurements of TEWL were made at birth (day 2) and at 2 and 6 months.

87 andomized clinical trial, prospective use of TEWL as a stopping criterion reduced anaphylaxis rates d

88 ldren with peanut allergy, suggesting use of TEWL could make OFC safer and more accessible.

89 The variation of TEWL as a function of SC removal behaved in a manner ent

90 istic regression model, day 2 upper quartile TEWL measurement was significantly predictive of AD at 1

91 Day 2 upper-quartile TEWL (>9 g water/m(2)/h) was a significant predictor of

92 RCM, TEWL, and FES are valuable non-invasive tools to quantit

93 Second, TEWL was measured using continuous monitoring.

94 The mean lip skin TEWL was found to be significantly higher, while the cap

95 impedance, apparently proceeded faster than TEWL decreased to the prestripping control.

96 The TEWL in AD(-)PA(+) subjects did not differ from that in

97 The TEWL rise occurred 48 minutes earlier than clinically ev

98 The TEWL score cut-off value predictive of recurrence was 24

99 icant correlations were observed between the TEWL measured at the anterior part of knee and hydration

100 .METHODSPhysicians and nurses blinded to the TEWL results conducted and adjudicated the results of al

101 osed wound site and reference skin, with the TEWL score as the sole predictor of recurrence.

102 cance of these observations was tested using TEWL to evaluate the permeability barrier function of th

103 nce showed an overall higher post-closure V0 TEWL score, compared to those who did not have a wound r

104 chi-square analysis demonstrated that the V0 TEWL score is a significant universal predictor of recur

105 We evaluated whether TEWL changes during an OFC could predict anaphylaxis ons

106 el of serological biomarkers associated with TEWL and hydration rate, as well as the emergence of AD

107 owed a significant negative correlation with TEWL, but a higher sensitivity to discriminate non-lesio

108 esional and/or nonlesional AD (FLG/FLG2 with TEWL; r < -0.4, P < .05).

109 temperature and skin blood flow but not with TEWL.