ライフサイエンスコーパス: TNF-alpha converting enzyme

1 allow cleavage by the metalloprotease TACE (TNF-alpha-converting enzyme).

2 activity of ADAM17, the membrane-associated TNF-alpha-converting enzyme.

3 ncreases the activity of the metalloprotease TNF-alpha-converting enzyme.

4 ed shedding, but shedding was independent of TNF-alpha-converting enzyme (a disintegrin and metallopr

5 tivation of the metalloprotease TACE/ADAM17 (TNF-alpha-converting enzyme), a previously unknown p53 t

6 gamma-Secretase and TNF-alpha converting enzyme activities were measured in

7 This enhanced TNF-alpha-converting enzyme activity significantly incre

8 The latter enzymes, as well as TNF alpha-converting enzyme and FasL-converting enzyme,

9 n CMV due to an enhanced activity of ADAM17 (TNF-alpha converting enzyme) and matrix metalloprotease

10 phil elastase, tumor necrosis factor [TNF]), TNF-alpha-converting enzyme, and matrix metalloproteinas

11 pparent deficiency in the level of the major TNF-alpha converting enzyme in adipose tissue to account

12 This enzyme (called the TNF-alpha-converting enzyme, or TACE) is a new member of

13 ages in a manner requiring activation of the TNF-alpha-converting enzyme TACE.

14 TNF alpha converting enzyme (TACE) processes precursor T

15 The tumor necrosis factor (TNF)-alpha converting enzyme (TACE/ADAM-17) is a transme

16 Here, we report that TNF-alpha converting enzyme (TACE) (a disintegrin and me

17 Using the TNF-alpha converting enzyme (TACE) inhibitor, TAPI-1, TP

18 pyl dicarboxylate were examined as potential TNF-alpha converting enzyme (TACE) inhibitors.

19 TNF-alpha converting enzyme (TACE) is a membrane-bound m

20 TNF-alpha converting enzyme (TACE) is a multidomain, mem

21 TNF-alpha converting enzyme (TACE) is the protease respo

22 TNF-alpha converting enzyme (TACE) or disintegrin and me

23 Endothelial deletion of the TNF-alpha converting enzyme (TACE) prevented the TNF-alp

24 sTNF is generated by TNF-alpha converting enzyme (TACE) proteolytic release o

25 TNF-alpha have centered on the inhibition of TNF-alpha converting enzyme (TACE) through the use of hy

26 ane protein that is enzymatically cleaved by TNF-alpha converting enzyme (TACE) to generate a 17-kDa

27 ct with epithelial cells, and by 1 h induced TNF-alpha converting enzyme (TACE) transcription.

28 The TNF-alpha converting enzyme (TACE), a disintegrin and me

29 In the present study, we demonstrate that TNF-alpha converting enzyme (TACE), a disintegrin and me

30 esothelin sheddase activity is mediated by a TNF-alpha converting enzyme (TACE), a member of the matr

31 ly in fibroblasts and monocytes deficient in TNF-alpha converting enzyme (TACE), a sheddase involved

32 F-related apoptosis-inducing ligand (TRAIL), TNF-alpha converting enzyme (TACE), TRAIL receptor (TRAI

33 (solTNF) molecule after being cleaved by the TNF-alpha converting enzyme (TACE).

34 yzed for expression of AR and its activator, TNF-alpha converting enzyme (TACE).

35 The TNF-alpha converting enzyme (TACE; a disintegrin and met

36 TNF-alpha converting enzyme (TACE; ADAM17), a member of

37 Tumor necrosis factor alpha (TNF-alpha) converting enzyme (TACE) is the first discove

38 ase (MAPK) and tumour necrosis factor-alpha (TNF-alpha) converting enzyme (TACE) were also assessed.

39 llagenase-1) or tumor necrosis factor-alpha (TNF-alpha) converting enzyme (TACE).

40 hown to involve tumor necrosis factor alpha (TNF-alpha) converting enzyme (TACE).

41 e (MT1-MMP) and tumor necrosis factor alpha (TNF-alpha)-converting enzyme (TACE) are prominent membra

42 Tumor necrosis factor alpha (TNF-alpha)-converting enzyme (TACE) is at the center of

43 uction, which corresponded to an increase in TNF-alpha-converting enzyme (TACE) activity.

44 TNF-alpha-converting enzyme (TACE) cleaves pro-TGF-alpha

45 Shedding mediated by TNF-alpha-converting enzyme (TACE) results in an unattac

46 Metalloprotease inhibitors and TNF-alpha-converting enzyme (TACE) small interfering RNA

47 rophages, by suppressing the activity of the TNF-alpha-converting enzyme (TACE), arguing that MUC1 is

48 lecular mass 26K which can be processed by a TNF-alpha-converting enzyme (TACE), to generate secreted

49 thelial (NCI-H292) cells via metalloprotease TNF-alpha-converting enzyme (TACE)-dependent EGFR activa

50 mucus, and its expression is modulated by a TNF-alpha-converting enzyme (TACE)-EGF receptor pathway

51 ionally by inhibiting cellular processing by TNF-alpha-converting enzyme (TACE).

52 TNF-alpha-converting enzyme (TACE, herein denoted as Ada

53 Targeting this protease, TNF-alpha-converting enzyme (TACE; also referred to as a

54 ADAM 17 (TNF-alpha converting enzyme, TACE) is a potential target

55 vation of the tmTNF cleavage metalloprotease TNF-alpha-converting enzyme via p38 MAP kinase activatio