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1 TPP is homologous to Escherichia coli type I signal pept
2 TPP likely is a major contributor to these biological ac
3 TPP might also be a promising platform for tumor-specifi
4 r (CP), 3, prepared from S = 1/2 Co(TPP), 1 (TPP = 5,10,15,20-tetraphenylporphyrin dianion), and S =
5 ic-structure analysis of [Fe(V)(N)(TPP)] (1, TPP(2-) = tetraphenylporphyrinato), and [Fe(V)(N)(cyclam
6 otal structural determination of Ag29(BDT)12(TPP)4, an atomically precise tetravalent nanocluster (NC
8 es indicate that many fungal species carry a TPP riboswitch with similar intron architecture, and the
9 undant theoretical metabolite database for a TPP of any topology (e.g., branched, multicyclic, etc.).
11 es cerevisiae) showed that all encode active TPP enzymes with an essential role for some conserved re
12 tive trait loci (QTLs) responsible for adult TPP mortality and fecundity in several RILs carrying ins
15 and previously uncharacterised low-affinity TPP binding-site was also observed, and hence indicated
16 sPbI(3) NCs, the stability of the LSCs after TPP treatments has been greatly improved, even after lon
18 n at saturating concentrations of Mg(2+) and TPP, the P1 helix, as well as distal regions surrounding
20 ntioxidant, while the BODIPY fluorophore and TPP ensure partitioning within the inner mitochondrial m
25 tween photorespiration and the TCA cycle, as TPP riboswitch mutants accumulate less photorespiratory
26 irect interaction between substrates such as TPP(+) and the essential residue E14 in transmembrane he
27 xymethylpyrimidine pyrophosphate, as well as TPP, but with an identical alternative splicing mechanis
28 lone-pair electrons on the phosphorus atom, TPP is also used as a photoinitiator, with higher effici
29 nalogue Mito-Met10, synthesized by attaching TPP(+) to Met via a 10-carbon aliphatic side chain, was
30 eposition of atomic silicon onto a free-base TPP layer on a Ag(100) surface under ultrahigh vacuum (U
34 d intermolecular electronic coupling between TPP(+) cations in TPP(2) ZnCl(4) than in the pristine or
45 on polymer (CP), 3, prepared from S = 1/2 Co(TPP), 1 (TPP = 5,10,15,20-tetraphenylporphyrin dianion),
47 ce hybrid repeat unit best formulated as [Co(TPP)](0.5+) hemication (Co(2.5+)) bound to a dithiadiazo
48 he isolated 2-methylimidazole Cobalt(II) [Co(TPP)(2-MeHIm)] and [Co(TTP)(2-MeHIm)], and the correspon
49 upramolecular cage Co-PB-1(6) bearing six Co-TPP subunits connected through twenty-four imine bonds.
50 We utilized cobalt tetraphenylporphyrin (Co-TPP), an oxygen reduction reaction (ORR) catalyst with h
51 atalysis in neutral pH water, whereas the Co-TPP monomer gives a 50 % mixture of H(2) O(2) and H(2) O
53 the molecular identification of the colonic TPP uptake system as the product of the SLC44A4 gene.
56 ts into the molecular mechanisms controlling TPP formation and transport to the cell surface, enablin
58 copy revealed the distribution of the fed CS-TPP-dsRNA nanoparticles in midgut, fat body and epidermi
60 ults showed that at a 5:1 weight ratio of CS-TPP to dsRNA, nanoparticles of less than 200 nm mean dia
67 l tris(o-phenylenedioxy)cyclotriphosphazene (TPP) is used as ahost for organizing dipolar molecular r
70 , tris(o-phenylenedioxy)cyclotriphosphazine (TPP, 1), using differential scanning calorimetry, solid-
72 ng ribosome binding, whereas most eukaryotic TPP riboswitches are predicted to regulate gene expressi
73 en the widespread distribution of eukaryotic TPP riboswitches and the diversity of their locations in
74 ) catalyzed by iron tetraphenylporphyrin (Fe(TPP)) in N, N'-dimethylformamide using decamethylferroce
76 iron meso-tetraphenylporphyrin chloride (Fe[TPP]Cl) complex in 1,1,1,3,3,3-hexafluoropropan-2-ol (HF
77 ustworthiness is payoff-maximizing will find TPP to be less net costly (for example, because mechanis
78 the WWTP ranged from 0.02 mg/day/person for TPP to 28.7 mg/day/person for TBOEP, whereas the emissio
79 re, we screened 11 wild tomato relatives for TPP resistance as potential resources for tomato (Solanu
80 eptide and that this process is required for TPP biosynthesis, indicating that the last step of TPP f
81 0.17 +/- 0.064 muM; and highly specific for TPP and not affected by free thiamine, thiamine monophos
84 of phleic acids onto diacyltrehalose to form TPP, and an MmpL transporter promotes the export of TPP
85 alternative splicing regulation by a fungal TPP riboswitch from Neurospora crassa, which is mostly l
86 d that combining BH3 mimetics and gamitrinib-TPP blunted cellular proliferation in a synergistic mann
89 stic investigations revealed that gamitrinib-TPP activated a PERK-dependent integrated stress respons
90 lementary experiments yielding Si-TPP and Ge-TPP on Ag(111) highlight the applicability to different
92 the hypothesis that the microbiota-generated TPP is absorbable and could contribute toward host thiam
94 e hybrids containing distinct metal halides, TPP(2) MX(n) (MX(n) =SbCl(5) , MnCl(4) , ZnCl(4) , ZnCl(
95 gnitude lower than the previously known high TPP-affinity and high-activity form, TK(high), in the pr
96 ll confocal imaging studies showed the human TPP transporter protein to be expressed at the apical me
100 wo sensitization steps (Fe(III)TPP --> Fe(II)TPP, and Fe(II)TPP --> Fe(I)TPP) both occur in <200 fs.
101 )](+)(,) forms the ferrous porphyrin, Fe(II)(TPP), which binds O(2) reversibly to form the ferric-sup
102 or the first two sensitization steps (Fe(III)TPP --> Fe(II)TPP, and Fe(II)TPP --> Fe(I)TPP) both occu
103 gnetic six-coordinate purple N-bound Co(III)(TPP)(N-py-DTDA(-))(O horizontal lineSMe2) complex (lambd
104 ane affords bright green diamagnetic Co(III)(TPP)(N-py-DTDA(-)), 3b, with multiple MLCT bands in the
105 ygen reduction is the protonation of Fe(III)(TPP)(O(2)(*-)) by pTsOH, which proceeds with a substanti
107 reduction of the ferric porphyrin, [Fe(III)(TPP)](+)(,) forms the ferrous porphyrin, Fe(II)(TPP), wh
109 lectronic coupling between TPP(+) cations in TPP(2) ZnCl(4) than in the pristine organic ionic compou
110 ly, many of these changes are not present in TPP riboswitch mutant plants, demonstrating their lack o
112 450 inhibitor PBO, or the esterase inhibitor TPP resulted in markedly increased mortality (to ~80%),
113 diagnose active TB for treatment initiation (TPP#1) and for a community-based triage or referral test
115 lphavbeta3-integrin antagonist IntegriSense, TPP exhibits a significantly higher tumor-to-background
116 Moreover, in contrast with IntegriSense, TPP reliably differentiates between tumor cells and cell
117 tors with transversely dipolar rotators into TPP channels is followed by solid-state nuclear magnetic
119 tosan (1-2.5%w/w) and BSA (0.25-10%w/w) into TPP solutions ranging in concentration from 0.1 to 10%w/
121 Direct interaction between (13)C-labeled TPP(+) and key residues within the EmrE dimer has been p
122 ate of membrane Hsp70, fluorescently labeled TPP is continuously internalized into syngeneic, spontan
123 A new BiLi porphyrin sandwich compound, LiBi(TPP)2 has been synthesized and characterized (TPP=tetrap
126 ate that plastidic SPI 1 (Plsp1) is the main TPP in Arabidopsis thaliana (Arabidopsis) although bioch
127 ributions within PDAC leads to microregional TPP values that vary on the hundred micron distance scal
130 d electronic-structure analysis of [Fe(V)(N)(TPP)] (1, TPP(2-) = tetraphenylporphyrinato), and [Fe(V)
132 nts provide a formal reputational account of TPP, and demonstrate how the costs of punishing may be r
133 negligible concentration of the C-2 anion of TPP, but of course not with an enzyme in modern biology.
134 understanding in intracellular behaviors of TPP in the course of targeting mitochondria due to the d
136 t the utilization of lower concentrations of TPP is a good approach to improve the protein retention
138 dissociation constants and cooperativity of TPP binding and provide the first comprehensive study ov
140 to protonophores; saturable as a function of TPP concentration, with an apparent Km of 0.17 +/- 0.064
141 To utilize the powerful functionality of TPP without the need for manual intervention to launch e
150 real-time visualization and quantitation of TPP dynamics within live cells at the subcellular level.
151 nzyme has been well documented, the roles of TPP in plant metabolism are still not fully understood.
152 s, the antineoplastic activity and safety of TPP(+)C10 warrant further comprehensive evaluation.
154 bcellular localization of the final stage of TPP biosynthesis and the chemical nature of the substrat
155 osynthesis, indicating that the last step of TPP formation occurs in the outer layers of the mycobact
157 ated with blended NPs composed of PLGA-b-PEG-TPP and a triblock copolymer containing a fluorescent qu
158 onsidering efficacy, the targeted PLGA-b-PEG-TPP NP provides a remarkable improvement in the drug the
162 phate FRs that included triphenyl phosphate (TPP), tris(4-butylphenyl) phosphate (TBPP), and a mix of
163 etween 4.14 ng/g dw for tripropyl phosphate (TPP) and 7290 ng/g dw for TBOEP; for ash, they were betw
165 omains of TPS and trehalose-6-phosphorylase (TPP) in tandem as a fused gene product of Escherichia co
167 study investigated their total polyphenols (TPP), catechins, caffeine, gallic acid and theanine.
170 tumor cell-penetrating peptide-based probe (TPP) recognizes an epitope of Hsp70 that is exclusively
172 h Organization (WHO) target product profile (TPP) criteria for a detection test and triage test to ev
173 f the high-priority target product profiles (TPP) published by the World Health Organization (WHO), t
174 applied MS-based thermal proteome profiling (TPP) to investigate the proteome-wide effects of missens
175 e application of thermal proteome profiling (TPP), a cellular thermal shift assay with an unbiased pr
177 rank test p = 0.11); treatment per-protocol (TPP) 78.1% (95% CI: 0.65 to 0.86) and 53.5% (95% CI: 0.3
180 n the case of the thiamine 5'-pyrophosphate (TPP) riboswitch from the Escherichia coli thiM gene enco
184 r this control is via thiamin-pyrophosphate (TPP) riboswitches, regions of the mRNA to which TPP can
185 the cooperativity of thiamine pyrophosphate (TPP) binding into the two active sites, in the presence
187 zes the last step of thiamine pyrophosphate (TPP) synthesis, the ATP-dependent phosphorylation of thi
188 o binds the cofactor thiamine pyrophosphate (TPP) with an affinity up to two-orders of magnitude lowe
195 s work, we report Total Polyphenols results (TPP) obtained by these two techniques from a set of nine
198 in, namely, silicon tetraphenylporphyrin (Si-TPP), by the deposition of atomic silicon onto a free-ba
201 ockdown and overexpression lines of a single TPP, AtTPPG, points to unique properties of individual T
203 ly, our data show that neither the substrate TPP nor protonation induces large-scale conformational c
204 ve probed the specific binding of substrates TPP(+) and MTP(+) to EmrE reconstituted into 1,2-dimyris
206 rted for a series of tetraphenylphosphonium (TPP) metal halide hybrids containing distinct metal hali
208 yrins 1(P1) (P1 = meso-tetraphenylporphyrin (TPP)) and 1(P2) (P2 = 3,5-Di(t)Bu-ChenPhyrin) with organ
209 para positions of the tetraphenylporphyrin (TPP) phenyls results in an important positive deviation
210 in a large-area carbon/tetraphenylporphyrin(TPP)/LiF/carbon junction, where the LiF layer provides m
211 merized with diluents (tetraphenylporphyrin, TPP), followed by pyrolysis to N-doped porous carbon sup
214 spectral SRS microscopy imaging reveals that TPP can maintain stable affinity to mitochondria during
217 y to a long-day photoperiod, suggesting that TPP also plays a role in metabolic acclimation to the ph
218 s study demonstrates for the first time that TPP enables organ-specific drug target engagement and id
223 ion and concomitant folding processes in the TPP riboswitch that culminate in the regulation of gene
225 evidence that the rate-limiting step in the TPP(+) transport cycle is not the outward-inward conform
227 or tests that have the potential to meet the TPP specifications, we hope to support harmonized eviden
228 ondingly, we posit that such features of the TPP aptamer domain contribute directly to the mechanism
229 maging to probe the folding landscape of the TPP aptamer domain in the absence and presence of magnes
233 rdinates with all four nitrogen atoms of the TPP macrocycle and interacts with a silver atom of the s
237 Injection of holes, i.e. formation of the TPP radical cation, inside the junction was monitored by
240 structural mechanism similar to that of the TPP riboswitch, including the guanine and adenine ribosw
241 provides insight into the plasticity of the TPP riboswitches but also shows that their maintenance i
243 This difference, that can reach 50% of the TPP value, was related to the presence of total sulphur
244 as 2 degrees C broader in the absence of the TPP(+) substrate versus its presence, which suggested th
246 a linear dependence of the SRS signal on the TPP concentration, we successfully establish a quantitat
247 x, as well as distal regions surrounding the TPP-binding site, exhibit an unexpected degree of residu
249 s without further labeling, we find that the TPP uptake causes little cytotoxicity to the host cells.
256 the weaker binding state is able to bind to TPP, but is unable to form a tertiary docking interactio
257 1:1, for unloaded ChNPs and 1:1:1 for Ch to TPP to CEO, for CEO-loaded ChNPs (CEO-ChNPs), were selec
263 ogy for the single-step reduction of TPPO to TPP using an aluminum anode in combination with a suppor
267 e demonstrate the broad applicability of TPE-TPP to monitor amyloid fibril aggregation, including und
268 triphenylphosphonium) tetraphenylethene (TPE-TPP)) with aggregation-induced emission characteristics
270 ith phos-phines, such as triphenylphosphine (TPP), 1,2-bis(diphenylphosphino)ethane [DPPE], and tris(
271 f the smallest clusters, triphenylphosphine (TPP)-stabilized undecagold, there are conflicting report
273 tic organic reactions-to triphenylphosphine (TPP) remains an unmet challenge that would dramatically
276 that is decorated with triphenylphosphonium (TPP) cations for detection of mitochondrial membrane pot
277 prepared via complexation with triphosphate (TPP) anions and were successively coated with hyaluronic
279 was cross-linked to sodium tripolyphosphate (TPP) to produce nano-sized polyelectrolyte complexes wit
280 ionic gelation with sodium tripolyphosphate (TPP), further encapsulated in ZN microparticles, were fo
281 ratios of chitosan (Ch) to tripolyphosphate (TPP), 1:1, for unloaded ChNPs and 1:1:1 for Ch to TPP to
282 ipids produced by Mycobacterium tuberculosis TPP production starts in the cytosol with the formation
283 1 showed processing activity against various TPP substrates at a level comparable to that of LepB.
286 nide was actually a better catalyst than was TPP in simple solution, where there is a negligible conc
288 +)/RPR(+), 88 were TPP(H)A(+)/RPR(-), 6 were TPP(H)A(-)/RPR(+), and 254 were negative for both tests.
289 ecimens, 241 were TPP(H)A(+)/RPR(+), 88 were TPP(H)A(+)/RPR(-), 6 were TPP(H)A(-)/RPR(+), and 254 wer
291 ) riboswitches, regions of the mRNA to which TPP can bind directly, thus facilitating fine-tuning to
292 multiantigen set performance approached WHO TPP criteria for clinical utility among HIV-uninfected a
300 phenylphosphonium Zinpyr-1 diacetate (DA-ZP1-TPP), is essentially nonfluorescent in the metal-free st