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1 TRAP is delivered using adenovirus- and vaccinia virus-b
2 TRAP proteins are thought to play an integral role in pa
3 TRAP staining showed that osteoclast numbers were reduce
4 TRAP+ osteoclast numbers were the highest in the STZ+L g
5 TRAPs, which remain hidden to prior flow diagnostics, th
6 , and tartrate-resistant acid phosphatase 5 (TRAP) with receptor activator of NF-kappaB ligand-evoked
7 and tartrate-resistant acid phosphatase 5b (TRAP-5b), and calcium and alveolar bone levels in rats w
8 of the malaria parasite Plasmodium express a TRAP family protein called merozoite-TRAP (MTRAP) that h
12 the chemokine ligand 5 (CCL5, RANTES); after TRAP activation, platelets release over 25 ng/mL CCL5.
14 8, the animals were sacrificed, serum B-ALP, TRAP-5b, and calcium levels were measured, gingiva speci
16 l traversal and hepatocyte invasion [3]; and TRAP, which is necessary for gliding motility and invasi
17 gingival IL-1beta and IL-10, serum B-ALP and TRAP-5b levels, or alveolar bone compared with conventio
18 gingival IL-1beta and IL-10, serum B-ALP and TRAP-5b, and calcium and alveolar bone levels between th
21 vity are associated with COPD and asthma and TRAP is involved in regulating macrophage migration.
23 ific to sporozoite surface-expressed CSP and TRAP proteins, but not intracellular glideosome-associat
24 This suggests that a combination of CSP and TRAP subunit vaccines could enhance protection against m
25 ell-known pre-erythrocytic antigens, CSP and TRAP, yet thousands of genes are expressed in the liver-
30 eated wounds at day 1 (P = 0.03), and P2 and TRAP induced a similar effect at days 3 (P = 0.002 and P
31 in the lung, heart, spleen, and plasma, and TRAP deposits were quantified in the lungs of both male
32 1beta; immunostaining increase for RANKL and TRAP; reduction of OPG and leukocytosis, which were sign
36 re, comparative analysis of whole-tissue and TRAP-selected mRNAs identified LPS-induced differences t
37 for trp operon attenuation beyond TrpL- and TRAP-mediated mechanisms described in other bacteria.
50 ethods: On the basis of the (68)Ga chelators TRAP (triazacyclononane-triphosphinate) and NODAGA, we s
51 tand the association between early childhood TRAP exposure, and subsequent asthma, allergies and sens
52 ggest pathological consequences from chronic TRAP exposure, including sex differences indicating fema
55 Osteoclastogenesis was assessed by counting TRAP-positive multinucleated cells in PB CD14+ monocytes
57 rovide several examples of a droplet digital TRAP (ddTRAP) assay for telomerase activity, including q
59 of a previously uncharacterized TERT domain (TRAP) with unanticipated interactions with the telomeras
65 anslating ribosome affinity purification (EC-TRAP) combined with high-throughput RNA sequencing analy
66 We then created a transgenic Pcp2-L10a-Egfp TRAP hPSC line to profile gene expression in differentia
67 As a first step, we used Tg(Pcp2-L10a-Egfp) TRAP mice to profile actively transcribed genes in devel
73 f several solute binding proteins (SBPs) for TRAP (tripartite ATP-independent permease) transporters
81 However, CX(3)CR1-expressing cells generated TRAP(+) OC on bone within 5 d in CX(3)CR1CreERT2/Ai14 td
82 ession levels of the osteoclast marker genes TRAP, Cathepsin K, dendritic cell-specific transmembrane
83 sus other groups were confirmed by a greater TRAP-positive cell number and reabsorption surface on bo
89 (TEN) and insertions in fingers domain (IFD)-TRAP regions of the human telomerase catalytic protein s
90 d or produced locally by leukocytes, impairs TRAP-mediated PGA formation to the same level as specifi
92 ly, expression of CathepsinK was detected in TRAP-negative cells of the inner periosteal layer also e
96 ter for carboxylate-containing substrates in TRAP transporters by engineering the SBP to recognize a
97 oscopy density in a published map, including TRAP in previously unassigned density as well as telomer
101 identified is a tripartite ATP-independent (TRAP) transporter, not previously associated with sugar
102 nvestigate impacts of air-cleaning on indoor TRAP levels and indoor chemistry in a renovated school a
106 RANKL) and Xanthine/Xanthine Oxidase induced TRAP mRNA expression in mouse macrophages, but only RANK
107 nds were tested for their ability to inhibit TRAP activity and [Au(4,4'-dimethoxy-2,2'-bipyridine)Cl2
109 levels of immature platelet fraction (IPF), TRAP-stimulated platelet surface CD42b, unstimulated pla
111 N-gamma exhibited low levels of Cathepsin K, TRAP, RANK, and tumor necrosis factor receptor-associate
115 d macrophage-specific polysomal RNA from Mac(TRAP) kidneys and conducted RNA sequencing followed by b
116 rization found no gross abnormalities in Mac(TRAP) mice and confirmed transgene expression across var
120 CS and 5 of 15 (33%) receiving ChAd63-MVA ME-TRAP demonstrated a delay in time to treatment, compared
121 the liver parasite burden, but ChAd63-MVA ME-TRAP remains the most promising antigenic insert for a v
125 adenovirus with a vaccine expressing the ME-TRAP malaria antigen had no significant effect on the im
126 o address this, we employed a viral-mediated TRAP (Targeted Recombination in Active Population) techn
127 press a TRAP family protein called merozoite-TRAP (MTRAP) that has been implicated in erythrocyte inv
129 en cells both in vitro and in vivo Using miR-TRAP affinity purification technology, we identified the
130 PD) and asthma compared to controls and more TRAP activity in lungs of mice with experimental COPD or
134 sors that differentiated into multinucleated TRAP-positive cells in the presence of EPAC-selective st
135 d reduced the total number of multinucleated TRAP+ cells in mice that received ligature attachment.
137 projections throughout the brain, PL neurons TRAPed later have a stronger functional recruitment of c
143 in D supplementation mitigates the effect of TRAP exposure on asthma development, asthma exacerbation
145 Different members of the DctP family of TRAP SBPs have binding sites that recognize a diverse ra
147 s unclear and potent selective inhibitors of TRAP are required to assess functional aspects of the pr
149 ut only long-term exposure to high levels of TRAP throughout childhood was associated with asthma dev
150 zones assumed to have the highest levels of TRAP, was positively associated with high-density lipopr
151 ty and traffic exposure zones, as markers of TRAP exposure, and metabolic biomarkers for cardiovascul
153 s is consistent with the known mechanisms of TRAP transporters and consider how the role of sugar oxi
154 ysis showed a significantly higher number of TRAP and Osteocalcin positive cells at 4 weeks in the ce
155 5), as identified by the increased number of TRAP(+) osteoclasts (P < 0.01) in the Tregs/pre-osteocla
159 Together, our findings support the power of TRAP-seq to identify cell type specific changes in gene
161 in biogenesis and sheds light on the role of TRAP in human congenital disorders of glycosylation.
162 The substrate binding proteins (SBP) of TRAP transporters are the best studied component and are
169 ereas higher-order complexes containing OST, TRAP, and TRAM were stabilized following substrate trans
171 stogenesis during homeostasis, we parabiosed TRAP tdTomato mice (CD45.2) on a C57BL/6 background with
174 els of thrombin receptor activating peptide (TRAP)-stimulated percent P-selectin- and activated glyco
175 ive (EMD), tyrosine-rich amelogenin peptide (TRAP), and a synthetic proline-rich peptide (P2) on acut
176 The tripartite ATP-independent periplasmic (TRAP) transporters are a widespread class of membrane tr
179 ned for tartrate-resistant acid phosphatase (TRAP) and immunohistochemical staining for five bone met
185 (OPG), tartrate-resistant acid phosphatase (TRAP), and activated caspase-3 were performed at the fur
186 RANKL), tartrate-resistant acid phosphatase (TRAP), and osteoclast-associated receptor increased sign
187 13) and tartrate-resistant acid phosphatase (TRAP), leading to an acceleration in periodontal breakdo
188 nd less tartrate-resistant acid phosphatase (TRAP)-positive cell induction than M0 or M2 macrophage t
189 creased tartrate-resistant acid phosphatase (TRAP)-positive cell number, and enhanced osteoclast acti
194 cleated tartrate-resistant acid phosphatase (TRAP)/cathepsin K(+) OCs expressing phosphorylated Janus
195 enzyme tartrate resistant acid phosphatase (TRAP, two isoforms 5a and 5b) is highly expressed in alv
197 stology (Tartrate-Resistant Acid Phosphatase-TRAP, Osteocalcin and human specific anti-mitochondria a
198 In a functional assay with physiological TRAP substrate osteopontin, AubipyOMe inhibited mouse ma
199 nship between traffic-related air pollution (TRAP) and risk factors for cardiovascular disease needs
201 rly childhood traffic-related air pollution (TRAP) exposure on development of asthma and allergies re
203 m exposure to traffic-related air pollution (TRAP) in relation to progression in physical disability.
205 h exposure to traffic-related air pollution (TRAP), but the TRAP-attributable burden remains poorly q
211 lated TRAP and AT showed that AT can prevent TRAP from binding to the trp leader RNA but cannot disso
213 5-, thrombospondin-related adhesion protein (TRAP) 130-138-, or circumsporozoite protein (CSP) 252-26
215 red thrombospondin-related adhesive protein (TRAP), provide only intermediate to low levels of protec
216 he thrombospondin-related anonymous protein (TRAP) family, is a secreted protein important for T. gon
219 called trp RNA binding Attenuation Protein (TRAP) controls attenuation of the tryptophan biosyntheti
220 tryptophan RNA-binding attenuation protein (TRAP), which binds its target RNA sequence close to the
221 dditionally, the trp 5'-UTR binds a protein, TRAP (tryptophan RNA-binding attenuation protein), which
222 l mechanism are the homo-oligomeric proteins TRAP (trp RNA-binding attenuation protein) and anti-TRAP
223 The telomere repeat amplification protocol (TRAP) for the human reverse transcriptase, telomerase, i
225 Translating ribosome affinity purification (TRAP) and in vitro luciferase reporter assay indicate th
226 translating ribosome affinity purification (TRAP) and RNA sequencing, TRAP-seq, in larval zebrafish
227 translating ribosome affinity purification (TRAP) and RNA-seq to identify mistranslating mRNAs in CA
230 Translating Ribosome Affinity Purification (TRAP) methodology to purify ribosome-associated mRNAs an
233 translating ribosome affinity purification (TRAP) to conduct transcriptomic analyses of caudate/puta
234 translating ribosome affinity purification (TRAP) with RNA sequencing to identify molecular changes
235 translating ribosome affinity purification (TRAP) with RNASeq to identify mRNAs in cortical axons pr
236 ranslational Ribosome Affinity Purification (TRAP)- approach and designed a transgene that expresses
241 sine Targeting by Recombinant Ab Pair, or pY-TRAP, for in vitro engineering of binders for native pY
245 tivated receptor 1 (PAR1) thrombin receptor (TRAP-stimulated P-selectin, activated GPIIb-IIIa, and CD
249 aser-capture microdissection and FACS, Retro-TRAP is a high-throughput methodology that requires mini
250 y purification coupled with deep-sequencing (TRAP-seq) in Caenorhabditis elegans, we have obtained hi
251 nity purification (TRAP) and RNA sequencing, TRAP-seq, in larval zebrafish to identify genes differen
253 table from a single velocity-field snapshot, TRAPs act as short-term attractors for all floating obje
254 pplied a new, responsive macrophage-specific TRAP mouse line, defining the translational profile of r
256 nchronously developing granule neurons (Sync-TRAP) showed that conditional knockout of the core NuRD
257 w domains of TER and TERT, including the TEN-TRAP complex, can interact in a conserved manner to regu
258 This ribosome entrapment pathway, termed TRAP (Translational Relocalization with Aberrant Polypep
260 n a growing body of evidence suggesting that TRAP exposures may accelerate aging-related declines in
261 vide biochemical and structural support that TRAP transporters function predominantly as high affinit
262 ferent ocean field experiments, we show that TRAPs computed from measured as well as modeled velociti
264 raffic-related air pollution (TRAP), but the TRAP-attributable burden remains poorly quantified.
269 d SBPs as well as permease components of the TRAP transporters, members of the DUF1537 family, and a
275 exhibited increased platelet aggregation to TRAP (thrombin receptor-activating peptide) (children wi
277 eek-old male and female rats were exposed to TRAP or filtered air for 14 months in a novel facility d
278 ion were higher in the rat hearts exposed to TRAP, with female rats being more susceptible than males
280 We sought to determine whether exposure to TRAP in middle age is associated with allergic sensitiza
285 Participants' time-weighted exposure to TRAP, from birth through age 7 years, was estimated usin
287 ne expressing a multiepitope string fused to TRAP and 3 doses of RTS,S/AS01B (group 1; n = 20) or 3 d
288 ibited the differentiation of macrophages to TRAP-positive osteoclasts, distinctive osteoclast specif
292 ide on the triazacyclononane-triphosphinate (TRAP) chelator, followed by automated (68)Ga labeling.
293 mpared to no protection using virus-vectored TRAP alone and 40% protection using adenovirus-CSP prime
294 es is seen when combined with virus-vectored TRAP, and the combination is no more protective than eit
296 rt of snoring was positively associated with TRAP aggregation (Kendall's tau-c = 0.23; P < 0.05).Conc
297 n conclusion, these data are consistent with TRAP SBPs undergoing a simple two-state transition from
298 SCs, their presence and co-localisation with TRAP-positive chondroclasts was noted in the vascular ch
299 nses was also achieved by combining R21 with TRAP-based viral vectors and protective efficacy was sig