ライフサイエンスコーパス: Thy

1 Thy-1 (-) and Thy-1 (+) fibroblast populations were trea

2 Thy-1 (-) fibroblasts responded to these stimuli with in

3 Thy-1 (-) lung fibroblasts transfected with Thy-1 also b

4 Thy-1 (CD90) is a 25-37 kDa glycosylphosphatidylinositol

5 Thy-1 (CD90) is a small GPI-anchored protein that is par

6 Thy-1 also affects numerous nonimmunologic biological pr

7 Thy-1 and alphavbeta3 integrin mediate bidirectional cel

8 Thy-1 and LAT clusters occur on membrane regions without

9 Thy-1 cross-linking, in the context of strong costimulat

10 Thy-1 in the retina is expressed predominantly in RGCs,

11 Thy-1 is a cell surface protein that is expressed during

12 Thy-1 is a marker of retinal ganglion cell (RGC) differe

13 Thy-1 is an important regulator of cell-cell and cell-ma

14 Thy-1 knockout mice had increased levels of both LTBP-4

15 Thy-1 low Sca-1+ Lineage- c-kit+ cells from old, reconst

16 Thy-1 physically couples to inactive alphavbeta3 integri

17 Thy-1 was expressed in some NS cells.

18 Thy-1(+) cells are also in rat fetal liver and exhibit p

19 Thy-1(+) cells in the OC niche are activated mesenchymal

20 Thy-1(+) fibroblasts displayed higher CD40 levels than d

21 Thy-1, a marker of hematopoietic progenitor cells, is al

22 Thy-1-integrin alpha(v)beta(5) interactions are RLD-depe

23 Thy-1/alphavbeta3 interactions stimulate astrocyte migra

24 molecule (EpCAM) and thymus cell antigen 1 (Thy-1)] were used for purification of freshly isolated c

25 Thymus cell antigen-1 (Thy-1)-expressing cells proliferate in the liver during

26 a primitive cell phenotype (c-kit+, SCA-1+, Thy-1+, CD31+, CD135neg, lineage neg), but only a minori

27 tic microbeads were enriched from 5.2%-87.2% Thy-1(+).

28 [N(4444)][Ad].2H(2)O, and thymine, [P(4444)][Thy].2H(2)O, as well as the double salt cocrystal, [P(44

29 Whereas 1 (11%) of every 8.9 Thy(low)Sca-1(+)lineage(-)Mac-1(+) fetal liver cells gav

30 In a Thy-1 null environment, BM ATA B cells progress to a nor

31 anoma cells by mechanisms likely involving a Thy-1-mediated adhesion of melanoma cells to EC.

32 hen the identical ATA BCR was expressed on a Thy-1 low/null background.

33 fragmentation pattern as authentic Thy[ c,a]Thy.

34 athic pulmonary fibrosis demonstrated absent Thy-1 staining within fibroblastic foci.

35 Force exponentially accelerated Thy-1/alphavbeta3 dissociation, indicating slip bond beh

36 Activated Thy-1(+) cells do not express OC genes but they express

37 Activated Thy-1(+) cells produce predominantly latent transforming

38 Activated Thy-1.2(+) T lymphocytes from WT mice treated in vitro w

39 the double salt cocrystal, [P(4444)](2)[Ad][Thy].3H(2)O.2HThy.

40 The Ade-Thy pair binding at 40-45% loading reveals that Thy mole

41 t DNA methylation in the minor groove at Ade/Thy- and/or Gua/Cyt-rich sequences.

42 Using adult Thy-1 GFP-M mice, we simultaneously recorded long-term s

43 have undergone T lineage specification after Thy-1 and CD25 up-regulation.

44 ce and humans that expressed the alloantigen Thy-1 (CD90), interleukin 2 (IL-2) receptor a-chain (CD2

45 Although Thy-1 low Sca-1+ Lineage- c-kit+ cells from young bone m

46 Although Thy-1(+) cells proliferate moderately after carbon tetra

47 Thy-1 (-) and Thy-1 (+) fibroblast populations were treated with plate

48 Therefore, we isolated Thy-1(+) and Thy-1(-) cells from embryonic day (ED) 14 fetal liver an

49 CR4) axis for stem cell homing, Thy-1(+) and Thy-1(-) fetal hepatic epithelial cells equally expresse

50 additional distinction between Thy-1(+) and Thy-1(-) human fibroblast subtypes has important consequ

51 ion is seen in rats after renal ablation and Thy-1 nephritis and in cultured murine podocytes in resp

52 y and for vimentin, smooth muscle actin, and Thy-1 immunoreactivity.

53 tion, as indicated by expression of B220 and Thy-1.2 on NK cells in chimeric mice at levels similar t

54 ior of a series of dyads derived from BP and Thy, separated by linear linkers of different length, ha

55 l expression of Sca-1, CD34, CD43, CD45, and Thy 1.2.

56 , suggesting an interaction between CD97 and Thy-1 that was further examined by adhesion and protein-

57 in binding was blocked partially by CD97 and Thy-1-blocking mAb.

58 We found that EpCAM(+) and Thy-1(+) cells represent two different populations of ce

59 l specific markers, neurofilament (NF-L) and Thy-1.

60 the mRNA level, we detected TEM1, TEM7, and Thy-1, specific markers of angiogenic endothelium.

61 meager increases in cells reactive with anti Thy-1, CXCR4 and CD133 in peripheral blood and allograft

62 enriched for SSCs by selection with an anti-Thy-1 antibody and cultured on STO (SIM mouse embryo-der

63 earing FDCs induced OVA-specific IgM in anti-Thy-1-pretreated nude mice and by purified murine and hu

64 m rats with resolving and proliferative anti-Thy-1 nephritis were examined for nitric oxide (NO) gene

65 ment of CD8 cells from CD4 KO mice with anti-Thy 1.2 plus complement abolished their effector functio

66 lly to immobilized Thy-1 protein, as well as Thy-1(+)-activated EC and CHO cells.

67 ame MS/MS fragmentation pattern as authentic Thy[ c,a]Thy.

68 Because Thy-1 (CD90) marks CAFs that promote tumor cell invasion

69 This additional distinction between Thy-1(+) and Thy-1(-) human fibroblast subtypes has impo

70 Removal or blocking of Thy-1, or blocking Thy-1-beta integrin interactions, decreased mEV uptake a

71 f the gold particle-induced clusters of both Thy-1 and CD73, a 5' exonucleotidase, occurred for perio

72 spacer could modulate the intramolecular BP/Thy photoreactivity, resulting in an enhanced selectivit

73 null mouse, signaling pathways modulated by Thy-1, the role of the GPI anchor in Thy-1 localization

74 d this correlated with liver repopulation by Thy-1(+) cells.

75 s available concerning liver repopulation by Thy-1(+) fetal liver cells.

76 mbrane potential (DeltaPsim)(lo), Ep-CAM(+), Thy-1(+), beta3-integrin(+) stem cells in neonate rat te

77 es become SSc(lo), DeltaPsim(hi), Ep-CAM(+), Thy-1(lo), beta3-integrin(-) stem cells in pup rat teste

78 at possess initiation activity (CD19(+)CD5(+)Thy-1(int)IgM(high)IgD(high)) that we name "initiator B

79 e induced in mice receiving anti-CD4, -CD8, -Thy-1.2, and -NK1.1 monoclonal antibodies (mAbs) on Days

80 fibroblasts with fibrogenic characteristics [Thy-1 (-) fibroblasts] responds to stimuli (bleomycin, i

81 CNT-Thy, simply recycled by centrifugation or filtration, ca

82 Thymine-modified CNTs (CNT-Thy) can be dispersed in solution in the presence of dia

83 by addition of DAT: the strong complementary Thy-DAT interaction inhibits crystallization of thymine

84 In conclusion, Thy-1 contributes to metastasis of melanoma cells by mec

85 d that human lung adenocarcinomas containing Thy-1(+) CAFs have a worse prognosis.

86 In contrast, Thy-1(-) fetal liver cells substantially repopulated nor

87 Here we report that compared to controls Thy-1-/- C57BL/6 mice displayed more severe histopatholo

88 d E-cadherin(+) cells were found in cultured Thy-1(-) cells, whereas nearly all CD45(+) cells were in

89 Orbital fibroblasts heterogeneously display Thy-1 and exhibit unique phenotypic attributes that may

90 cally to Thy-1(+)-activated human dermal EC, Thy-1(+) CHO cells, and immobilized Thy-1 protein.

91 Highly enriched Thy-1(+) ED14 fetal liver cells proliferate and repopula

92 Cells that co-express Thy-1 and alpha-smooth muscle actin (alphaSMA), a CAF ma

93 vated in vitro stellate cells do not express Thy-1.

94 ion of portal fibroblasts (PFs) that express Thy-1, fibulin 2, and the recently identified marker mes

95 The loss of RGCs expressing Thy-1 after optic nerve injury has an initial phase of r

96 essive loss in the number of RGCs expressing Thy-1.

97 on, whereas non-fibrogenic Thy-1-expressing [Thy-1 (+)] fibroblasts do not.

98 enic injury promotes loss of lung fibroblast Thy-1 expression, resulting in enhanced fibrogenesis.

99 osis factor-alpha induced loss of fibroblast Thy-1 surface expression in vitro, which was associated

100 We propose that fibroblast Thy-1 display pre-determines lineage to a contractile or

101 TGF)-beta activation, whereas non-fibrogenic Thy-1-expressing [Thy-1 (+)] fibroblasts do not.

102 ately estimating specific rupture forces for Thy-1-Fc/alphavbeta3-Fc dissociation and calculating the

103 id cells, as a novel interacting partner for Thy-1.

104 RBPMS-positive cells were also positive for Thy-1, neurofilament H, and III beta-tubulin.

105 -linking by specific mAb suggests a role for Thy-1 in mouse T lymphocyte activation.

106 naling capacity suggests a possible role for Thy-1 in the maintenance of T cell homeostasis in the ab

107 This represents a novel role for Thy-1 in the regulation of fibroblast-matrix interaction

108 Fetal liver cells selected for Thy-1 expression using immunomagnetic microbeads were en

109 tic progenitor cell population distinct from Thy-1(-) stem/progenitor cells, which repopulate the nor

110 Furthermore, Thy-1 expression prevents fibroblast contraction-induced

111 rradiation, Thy molecules dimerize into Thy<>Thy.

112 we describe a Lin(Neg) Sca-1(Pos) c-kit(Hi) Thy-1.1(Neg) L-selectin(Pos) adult mouse bone marrow pop

113 eceptor 4 (CXCR4) axis for stem cell homing, Thy-1(+) and Thy-1(-) fetal hepatic epithelial cells equ

114 However, how Thy-1 supports cell-cell adhesion in a dynamic mechanica

115 However, Thy-1 deletion did not affect subcutaneous primary tumor

116 at in vivo administration of IL-7 to SCID-hu Thy/Liv mice does not appear to enhance thymocyte surviv

117 d with human fetal thymus and liver (SCID-hu Thy/Liv mice), in which virus-mediated depletion of thym

118 In HIV-1-infected SCID-hu Thy/Liv mice, T-20 lost activity with infrequent dosing,

119 (low) T cells, we used the humanized SCID-hu Thy/Liv mouse model to show that HIV infection of the th

120 ity both in vitro and in vivo in the SCID-hu Thy/Liv mouse model.

121 n severe combined immunodeficient (SCID)-hu (Thy/Liv) mice.

122 tly infected cells generated in the SCID-hu (Thy/Liv) mouse demonstrated no functional viral RNA prod

123 ctivity was found in the MHC class I (MHC-I)-Thy-1+c-kit- cell fraction of the mouse cryptorchid test

124 heir surface phenotype was found to be MHC-I+Thy-1-Sca-1+, and the transplantation assay demonstrated

125 Used as a probe to identify Thy-1(+) CAF-enriched tumors in a compendium of 1,586 lu

126 itation, 490 nm detection) was used to image Thy-1 CFP mice aged 6 to 9 months (n = 5) before optic n

127 rmal EC, Thy-1(+) CHO cells, and immobilized Thy-1 protein.

128 luble CD97 bound specifically to immobilized Thy-1 protein, as well as Thy-1(+)-activated EC and CHO

129 In Thy-1 nephritis in Lewis rats, IFN-beta started at induc

130 ated by Thy-1, the role of the GPI anchor in Thy-1 localization to lipid rafts and signaling, and reg

131 Changes in Thy-1 and NF-L immunoreactivities were also observed.

132 -4-bound large latent TGF-beta1 complexes in Thy-1 (-) fibroblasts to significantly higher levels tha

133 m the expression and localization of CTGF in Thy-1+ oval cells.

134 candidate genes differentially expressed in Thy-1+ oval cells, in this liver injury model.

135 ividual pial arterioles on motor function in Thy-1 line 18 channelrhodopsin-2 (ChR2) transgenic mice

136 ed in CA1 principal cells of Pin1(-/-) or in Thy-1GFP mice treated with the pharmacological inhibitor

137 regional lymph nodes was clearly reduced in Thy-1(-/-) mice.

138 induces transient phosphorylation of SFKs in Thy-1-expressing fibroblasts only.

139 lasts to significantly higher levels than in Thy-1 (+) fibroblasts.

140 by disrupting the formation of an inhibitory Thy-1-TGFbetaRI complex.

141 UV irradiation, Thy molecules dimerize into Thy<>Thy.

142 and Schmidt rules, and upon UV irradiation, Thy molecules dimerize into Thy<>Thy.

143 Therefore, we isolated Thy-1(+) and Thy-1(-) cells from embryonic day (ED) 14 f

144 r the presence of Thy-1(+) CAFs, we isolated Thy-1(+) CAFs and normal lung fibroblasts (LFs) from the

145 mined by flow cytometric analysis of c-Kit(+)Thy-1.1(lo)Lin(-)Sca-1(+) (KTLS) cells.

146 Mice lacking Thy-1 showed markedly diminished experimental lung metas

147 At the single-molecule level, Thy-1 is capable of independently binding alpha5beta1 in

148 s expressing a stem cell phenotype (lineage-/Thy-1+) supported a productive HCMV infection.

149 In normal liver, Thy-1(+) cells are a heterogeneous population: those loc

150 lpha(+)Flt3(-) precursors that were c-kit(lo)Thy-1(hi) generated T lineage cells when cultured on OP9

151 center (GC) marker CXCR5, and is Vbeta5(low)Thy-1(low).

152 N2 colocalized with the ganglion cell marker Thy 1.2 and with the Muller cell marker vimentin, confir

153 sly reported hematopoietic stem cell markers Thy-1, c-kit, and CD34 or the neuroepithelial marker neu

154 tle or no colocalization of the raft markers Thy-1, GM1, and LAT with each other or with FcepsilonRI

155 -endothelial cell adhesion molecule, Megsin, Thy-1, PDGF receptor alpha, and vascular alpha-actin) an

156 The cell adhesion molecule Thy-1 (CD90) mediates the adhesion of melanoma cells to

157 Endothelial surface molecule Thy-1 (CD90) is implicated in the metastatic process thr

158 alpha-SMA), collagen, and adhesion molecules Thy-1/CD90 and alpha(v) beta(3) and beta(5) integrins.

159 gene (GFP), and the other encoding the mouse Thy-1 gene and GFP.

160 logical ligand or counterreceptor for murine Thy-1 in the lymphoid compartment has not yet been ident

161 The murine Thy-1 (mThy1)-alpha-syn transgenic (tg) model recapitula

162 teractions are RLD-dependent because mutated Thy-1, in which RLD is replaced by RLE, loses the abilit

163 Lineage-negative Thy-1+CXCR4+CD133+ stem cells were significantly increas

164 compartment can promote a relatively normal Thy-1(+) TCRalphabeta(+) T cell pool from the limited po

165 Interestingly, only Thy-1(-), but not Thy-1(+) subsets differentiated to lipofibroblasts, as d

166 /- 5.3%, 4.2% +/- 3.1%, and 3.3% +/- 2.1% of Thy-1-expressing RGCs remaining at weeks 1, 2, 3, 10, an

167 More than 95% of Thy-1 antigen-positive cells in the retina expressed the

168 Activation of Thy-1 can promote T cell activation, and this role of Th

169 e patches independently of each other and of Thy-1.

170 roblast populations selected on the basis of Thy-1 expression by cell sorting were examined for respo

171 Removal or blocking of Thy-1, or blocking Thy-1-beta integrin interactions, dec

172 ss-linking of Thy-1 promotes coclustering of Thy-1 with LAT, but not with GM1.

173 Colocalization of Thy-1 antigen and ctgf signals by in situ hybridization

174 caused a reduction in the retinal content of Thy-1 and NF-L mRNAs and immunoreactivities.

175 ls of mouse gamma-synuclein under control of Thy-1 promoter.

176 bit lamellar order and 2D crystallization of Thy in the bulk.

177 t, lack of Thy-1 expression or disruption of Thy-1-alpha(v)beta(5) interactions renders lung fibrobla

178 Disruption of Thy-1-alphavbeta3 coupling altered recruitment of Src fa

179 nisms underlying the anti-fibrotic effect of Thy-1 are not well understood.

180 Elimination of Thy-1.2(+) cells in mice given mAb to CD4 and CD8 transf

181 lls that gradually discontinue expression of Thy-1 and begin to express cytokeratins.

182 Despite its expression of Thy-1 and NMDA receptors, as found in primary RGCs, this

183 us with respect to the surface expression of Thy-1 differ markedly in morphology, cytoskeletal organi

184 broblasts lacking cell surface expression of Thy-1 glycoprotein, suggesting that Thy-1 modulates the

185 Here, we report a strong expression of Thy-1 on both blood vessel and lymphatic EC in melanoma

186 onstrated that lung fibroblast expression of Thy-1 prevents lung fibrosis.

187 s, Ki-67 staining and relative expression of Thy-1, alpha smooth muscle actin (alpha-SMA), and fibron

188 on also increased the relative expression of Thy-1, alpha-SMA, and fibronectin in anterior and poster

189 de in fibroblasts requires the expression of Thy-1, although it does not appear to function as a stab

190 Consistent with a known function of Thy-1 in regulating lipid raft-associated signaling, int

191 In reviewing the nonimmunologic functions of Thy-1, we discuss the phenotype of the Thy-1 null mouse,

192 factor-alpha were identified as inducers of Thy-1 expression on EC in vitro.

193 After a single injection of Thy-1 antibody the cells generated large amounts of NO t

194 These data suggest that the interaction of Thy-1 with beta integrins mediates mEV uptake by lung fi

195 as implemented to analyze the interaction of Thy-1-Fc with nonpurified alphavbeta3-Fc integrin, where

196 In contrast, lack of Thy-1 expression or disruption of Thy-1-alpha(v)beta(5)

197 ed by measurement of total retinal levels of Thy-1 and NF-L mRNAs and NF-L protein.

198 effects were not seen after cross-linkage of Thy-1, another GPI-anchored protein, and were dependent

199 External cross-linking of Thy-1 promotes coclustering of Thy-1 with LAT, but not w

200 These included the localisation of Thy-1 and choline acetyltransferase, the a- and b-wave a

201 We first examined the location of Thy-1(+) CAFs within human lung adenocarcinomas.

202 brosis, previous work has shown that loss of Thy-1 (CD90) expression in fibroblasts correlates with r

203 derivative (OT-440) protects against loss of Thy-1 promoter activation following optic nerve crush an

204 Loss of Thy-1 was sufficient to induce myofibroblast differentia

205 The majority of Thy-1(+) cells located at the lobular interface and in t

206 plied to calculate the kinetic parameters of Thy-1/alphavbeta3 dissociation.

207 man lung cancer database for the presence of Thy-1(+) CAFs, we isolated Thy-1(+) CAFs and normal lung

208 Recruitment and proliferation of Thy-1+ oval cells is a hallmark of liver regeneration af

209 Optic nerve injury triggers reduction of Thy-1 promoter activation followed by retinal ganglion c

210 lipid rafts and signaling, and regulation of Thy-1 expression.

211 The physiological role of Thy-1 for lymphogenic and hematogenic metastasis of mela

212 promote T cell activation, and this role of Thy-1 is reviewed elsewhere.

213 (EGFP) fluorescence from the brain slices of Thy-1 EGFP transgenic mice, we show that there is an inh

214 Subcloning of Thy-1(+) cells from OC-activated livers yield Thy-1(+) f

215 The unresponsiveness of Thy-1 (+) cells is not because of defective TGF-beta sig

216 The self-complementary systems based on Thy exhibit lamellar order and 2D crystallization of Thy

217 Interestingly, only Thy-1(-), but not Thy-1(+) subsets differentiated to lip

218 port we investigated whether Thy-1(+) and/or Thy-1(-) fibroblasts were capable of differentiating int

219 Morphometric analyses of neurofilament- or Thy-1-positive cells, retinal ganglion cells (flat prepa

220 (3) The orphaned Thy residue displays structural flexibility by adopting

221 taining double-stranded base pairs, Cyt/Oxa, Thy/Oxa, Ade/Oxa, and Gua/Oxa, with no preference to bas

222 red amyloid through cranial windows in PDAPP;Thy-1:YFP double-transgenic mice using the in vivo amylo

223 es are relatively stable structures in PDAPP;Thy-1:YFP transgenic mice over several days.

224 uritic plaques in the brains of living PDAPP;Thy-1:YFP transgenic mice, a model that develops AD-like

225 defined as c-kit(pos)Lin(neg/low)Sca-1(pos)-Thy-1.1(neg)Flt3(pos), Sca-1 and CD62L resolved four pop

226 in both mice and humans, were predominantly Thy-1-positive.

227 the glycophosphatidylinositol-linked protein Thy-1 affects proliferation and myofibroblast differenti

228 glycosylphosphatidylinositol-linked protein Thy-1, the ganglioside GM1, palmitoylated LAT, and cross

229 r (MACS) technique, we successfully purified Thy-1 positive RGCs with nearly 95% purity.

230 Rather, Thy-1 (-) fibroblasts activate latent TGF-beta in respon

231 By defining how force regulates Thy-1/alphavbeta3 integrin binding, we provide an initia

232 Remarkably, Thy-1 cross-linking also results in the potent costimula

233 duced changes in the localisation of retinal Thy-1 and ChAT immunoreactivities.

234 autoreactive BCR knock-in mice lacking self-Thy-1 ligand, immunoglobulin light chain editing occurre

235 ptor (BCR) mouse line, specific for the self-Thy-1/CD90 glycoprotein, we demonstrate that BCR crossli

236 ssion but inhibited expression of alpha-SMA, Thy-1/CD90, and alphav beta(3) integrins.

237 tes, and diminished expression of alpha-SMA, Thy-1/CD90, and beta(3) integrins compared with control

238 Sorted Thy-1+ oval cells expressed a high level of CTGF gene in

239 , all under the control of a neuron-specific Thy-1 promoter.

240 6P) under the control of the neuron-specific Thy-1 promoter; referred to here as 'APPPS1').

241 ctionalized polymers, through supramolecular Thy/DAT association.

242 and LPL expressed a phenotype, TCRalphabeta+ Thy-1+ CD8+ similar to that expressed on reovirus 1/L-st

243 Therefore, we conclude that Thy-1 surface expression is required for thrombospondin-

244 in situ hybridization further confirmed that Thy-1+ oval cells were a source of CTGF.

245 t to fibrogenic stimulation, indicating that Thy-1 is a critical biological response modifier that pr

246 pair binding at 40-45% loading reveals that Thy molecules are packed within the channels in a way th

247 We now show that Thy-1 is a regulator of fibroblast rigidity sensing.

248 Here we show that Thy-1 supports beta1 integrin- and syndecan-4 (Syn4)-med

249 In this study, we showed that Thy-1 interacts with integrin alpha(v)beta(5), both in a

250 It is shown that Thy-1(+) cells are mesenchymal cells with characteristic

251 These data suggest that Thy-1-integrin alpha(v)beta(5) interactions inhibit cont

252 ssion of Thy-1 glycoprotein, suggesting that Thy-1 modulates the fibrogenic potential of fibroblasts.

253 inase-3 (GSK-3beta) transgene, driven by the Thy-1 promoter so limiting its localization predominantl

254 In the gut, the Thy-1(+)TCRalphabeta(+) intraepithelial lymphocyte (IEL)

255 Nonetheless, how the Thy-1/alphavbeta3 interactions respond to mechanical cue

256 whereas nearly all CD45(+) cells were in the Thy-1(+) fraction.

257 ns of Thy-1, we discuss the phenotype of the Thy-1 null mouse, signaling pathways modulated by Thy-1,

258 yan fluorescent protein under control of the Thy-1 promoter (Thy1-CFP mice) to determine how the alph

259 yan fluorescent protein under control of the Thy-1 promoter (Thy1-CFP mice) was imaged using a blue-l

260 uorescent protein (CFP) under control of the Thy-1 promoter received MS-275 (subcutaneous) or vehicle

261 ets of a selective dissociating agent of the Thy/DAT association (DMSO).

262 1 in 8.5 for pup) enabled us to predict the Thy-1 and beta3-integrin status of stem cells in neonate

263 injected, yet a number of mice receiving the Thy/Liv implant alone, with no HSPC injection, were also

264 uantitative axonal loss, suggesting that the Thy-1 (CFP) transgenic mouse strain is appropriate for R

265 nt reporter protein (CFP) gene linked to the Thy-1 promoter, which expresses CFP in RGCs.

266 ice overexpressing alpha-synuclein under the Thy-1 promoter (ASO) show abnormal accumulation of alpha

267 partment is surprisingly intact, whereas the Thy-1(-)TCRalphabeta(+) subset is almost completely abse

268 displayed higher CD40 levels than did their Thy-1(-) counterparts and were largely responsible for t

269 Thus, Thy-1 marks a CAF population that adversely impacts clin

270 sed on poly(propylene oxide) (PPO), thymine (Thy), and diaminotriazine (DAT).

271 al and computational approach, that thymine (Thy) molecules diffuse through the pores of the MOF and

272 ant BP/DNA interactions occurs with thymine (Thy).

273 Increased anti-thymocyte/Thy-1 autoreactive (ATA) BCR cells in the B1 B cell subs

274 In anti-thymocyte/Thy-1 autoreactive BCR knock-in mice lacking self-Thy-1

275 tion of human fetal liver and thymus tissue (Thy/Liv) plus intravenous injection of autologous liver-

276 signals is governed, in part, by binding to Thy-1 (CD90) on activated endothelial cells (EC).

277 yn4, the two receptors bind cooperatively to Thy-1, to form a trimolecular complex.

278 mutations in the RpoB gene, 20% were Gua to Thy transversions.

279 ration and cytokine synthesis in response to Thy-1 cross-linking by specific mAb suggests a role for

280 overexpressing CD97 adhered specifically to Thy-1(+)-activated human dermal EC, Thy-1(+) CHO cells,

281 The transgenic Thy-1-YFP mouse line, in which a small number of RGCs ar

282 In normal rat liver, transplanted Thy-1(+) cells produced only rare, small DPPIV(+) cell c

283 In retrorsine-treated liver, transplanted Thy-1(+) fetal liver cells achieved a 4.6%-23.5% repopul

284 ct with cyan fluorescent protein (CFP) under Thy-1 promoter control, and a construct with beta-galact

285 tissue by a modified panning technique using Thy 1.1 antibody.

286 lustering of integrin and membrane rafts via Thy-1's glycophosphatidylinositol tether.

287 fty-five percent (SD 4.4%) of EOM-Fibro were Thy-1 positive compared with only 24% (SD 4.4%) of LM-Fi

288 rentiation in bleomycin-induced lesions were Thy-1-negative.

289 smooth muscle actin and fibronectin, whereas Thy-1 (+) fibroblasts resisted stimulation.

290 a in response to fibrogenic stimuli, whereas Thy-1 (+) cells fail to do so.

291 In this report we investigated whether Thy-1(+) and/or Thy-1(-) fibroblasts were capable of dif

292 pression in vitro, which was associated with Thy-1 shedding, Smad phosphorylation, and myofibroblast

293 ium mediated by the interaction of CD97 with Thy-1 is involved in firm adhesion of PMNC during inflam

294 ions, CD97(+) myeloid cells colocalized with Thy-1(+) EC of small vessels in microabscesses, suggesti

295 hematopoietic stem cells in conjunction with Thy-1+, CD34+, and lineage-specific markers.

296 nt of isolated cells were immunolabeled with Thy 1.1 antibody.

297 ested that CD97 interacts via its stalk with Thy-1 because mAb directed to the stalk of CD97 showed s

298 Thy-1 (-) lung fibroblasts transfected with Thy-1 also become resistant to fibrogenic stimulation, i

299 napses in somatosensory cortex of Line-H-YFP Thy-1 transgenic mice.

300 hy-1(+) cells from OC-activated livers yield Thy-1(+) fibroblastic cells and a population of E-cadher