ライフサイエンスコーパス: Tribolium

1 le being lost in the lineage leading towards Tribolium.

2 group to the clade containing Drosophila and Tribolium.

3 by specific functions of toy, ey and dac in Tribolium.

4 enhancer to bypass the ladybird insulator in Tribolium.

5 xtent to which this paradigm is conserved in Tribolium.

6 cle (otd), has a bcd-like role in the beetle Tribolium.

7 larval, pupal, and adult cuticle tanning in Tribolium.

8 ons described for hunchback in Drosophila or Tribolium.

9 pears to be conserved between Drosophila and Tribolium.

10 n-cryptonephridial region of renal tubule of Tribolium.

11 in a cross-species manner in Drosophila and Tribolium.

12 ial)(5)(,)(6) between Daphnia, Parhyale, and Tribolium.

13 ues, as well as for four embryonic stages of Tribolium.

14 and castor during segmentation in the beetle Tribolium.

15 issue-specific Gal4-UAS binary expression in Tribolium.

16 inhibited for proper anterior development in Tribolium.

17 In Tribolium, a short germ beetle, giant is required for se

18 We find that in Tribolium, Abd-A, but not Ubx, represses early expressio

19 We have identified two Tribolium ac/sc genes - achaete-scute homolog (Tc-ASH) a

20 Our analysis of the Tribolium ac/sc genes indicates significant plasticity i

21 CRF-like diuretic hormone (DH37 and DH47 of Tribolium), adipokinetic hormone (AKH), eclosion hormone

22 f many additional osmoregulatory peptides in Tribolium agrees well with its ability to live in very d

23 etter, the sentence starting: 'For instance, Tribolium and Drosophila inflated are direct targets of

24 Evidence from both Tribolium and Drosophila suggests that this ancestral ge

25 eposited microRNAs that is conserved between Tribolium and Drosophila.

26 studies have shown that, in the flour beetle Tribolium and in the milkweed bug Oncopeltus, the homeob

27 efined in Drosophila is largely conserved in Tribolium and is also used to pattern the elytra.

28 Both genes occur only in Tribolium and not in other holometabolous insects with a

29 ning, growth and morphogenetic mechanisms in Tribolium and other arthropod species.

30 In Tribolium and other intermediated germ band insects, the

31 amily exhibit striped expression (as seen in Tribolium and previously reported in Drosophila [3-5]) i

32 uences link them to the Antp-class genes and Tribolium and Schistocerca orthologs have Antp-class YPW

33 necessary for neural precursor formation in Tribolium and sufficient for neural precursor formation

34 ommonly studied arthropods--the flour beetle Tribolium and the common house spider--provides evidence

35 Pax group III genes in both the flour beetle Tribolium and the grasshopper Schistocerca is remarkably

36 , convenient genome size and organization of Tribolium, and its relatively long phylogenetic divergen

37 rlie neural pattern formation in Drosophila, Tribolium, and potentially all insects, but that subtle

38 In addition, we found that the Tribolium apterous genes are not only essential for exos

39 n contrast to Drosophila, eggs of the beetle Tribolium are protected by a serosa, an extraembryonic e

40 We put forward Tribolium as a model for studying a more ancestral mode

41 h the AP patterning of the short-germ beetle Tribolium as a model system to study dynamic and tempora

42 ace appears to be present in Parhyale(7) and Tribolium as a small, inconspicuous protrusion.

43 ing Drosophila at the anterior and ancestral Tribolium at the posterior.

44 established an enhancer prediction system in Tribolium based on time- and tissue-specific ATAC-seq an

45 We show that research using Tribolium beetles has contributed a substantial amount t

46 Furthermore, from the Tribolium black mutant and dsTcADC-injected insects both

47 were all able to identify the six species of Tribolium both rapidly and accurately.

48 that similar Scr phenotypes are observed in Tribolium but not in Drosophila or Oncopeltus reveals th

49 distinguishable from amniotic cells, like in Tribolium but unlike in Drosophila, in which zen control

50 al) are essential for embryo segmentation in Tribolium but, in Drosophila, function in terminal epide

51 Both Robos from Tribolium can mediate midline repulsion in Drosophila, b

52 mortality of adults of the red flour beetle, Tribolium castaneum (Herbst) and the confused flour beet

53 dy was undertaken to assess the potential of Tribolium castaneum (Red flour beetle) acetylcholinester

54 mutant allele classes of Cephalothorax, the Tribolium castaneum (red flour beetle) ortholog of Sex c

55 of variability in a laboratory population of Tribolium castaneum (red flour beetle), whereas using on

56 as putative Cry3Ba toxin-binding proteins in Tribolium castaneum (Tc) larvae.

57 d ADC and DDC genes in the red flour beetle, Tribolium castaneum (Tc), and investigated their functio

58 ase-like proteins from the red flour beetle, Tribolium castaneum (Tc), were examined by using gene-sp

59 fied homolog of dsx in the red flour beetle, Tribolium castaneum (Tcdsx).

60 ically test the function of the elytra using Tribolium castaneum (the red flour beetle) as a model.

61 In the insects Drosophila melanogaster and Tribolium castaneum achaete-scute homologues are initial

62 rotein extracts of elytra (wing covers) from Tribolium castaneum adults.

63 epidoptera) were not inhibited by AhAI while Tribolium castaneum and Callosobruchus chinensis (Coleop

64 demonstrated high similarity with the ELO of Tribolium castaneum and Drosophila melanogaster.

65 However, in the beetle Tribolium castaneum and most other arthropods, a number

66 Tribolium castaneum and Rhyzopertha dominica are cosmopo

67 ities) between two species of flour beetles, Tribolium castaneum and T. freemani.

68 ies experimental system of the flour beetles Tribolium castaneum and Tribolium confusum, we show that

69 s on new arthropod models such as the beetle Tribolium castaneum are shifting our knowledge of embryo

70 dium ion channel paralytic A (TcNav) gene in Tribolium castaneum as a viable means of controlling thi

71 we address this question in the flour beetle Tribolium castaneum by analyzing and comparing the devel

72 present the high-resolution structure of the Tribolium castaneum catalytic subunit of telomerase, TER

73 ound to be widespread in wild populations of Tribolium castaneum collected in Europe, North and South

74 Tribolium castaneum developed in metal silos, deltamethr

75 nd experimental validation in a model insect Tribolium castaneum evolving against two coinfecting bac

76 ng replicate populations of the model insect Tribolium castaneum exposed to over 10 years of experime

77 ng replicate populations of the flour beetle Tribolium castaneum for 6 to 7 years under conditions th

78 found that the hAT transposase TcBuster from Tribolium castaneum formed filamentous structures, or ro

79 Tribolium castaneum has emerged as a model for brain dev

80 The red flour beetle Tribolium castaneum has emerged as a powerful model in i

81 Drosophila melanogaster, Apis mellifera and Tribolium castaneum have 23, 21 and 24, respectively.

82 The Tribolium castaneum homeotic gene maxillopedia (mxp) is

83 rising MCU and EMRE subunits from the beetle Tribolium castaneum in complex with a human MICU1-MICU2

84 een replicated invasions of the flour beetle Tribolium castaneum in laboratory microcosms.

85 Tribolium castaneum is a globally significant post-harve

86 Tribolium castaneum is a member of the most species-rich

87 We show that Medea(1) activity in Tribolium castaneum is associated with a composite Tc1 t

88 eotic Abdominal gene of the red flour beetle Tribolium castaneum is associated with an insertion of a

89 th the blastoderm and germband of the beetle Tribolium castaneum is based on the same flexible mechan

90 The red flour beetle Tribolium castaneum is widely used as a model insect spe

91 Tribolium castaneum paired (Tc-prd) and sloppy-paired (T

92 We report the structure of Tribolium castaneum PINK1 (TcPINK1), revealing several u

93 d in holometabolous insects as TcE93 RNAi in Tribolium castaneum prevented pupal-adult transition and

94 neurons in the brain of the red flour beetle Tribolium castaneum respond to internal changes in osmol

95 Here, we show that an antioxidant enzyme, Tribolium castaneum superoxide dismutase 6 (TcSOD6), is

96 netic studies in Drosophila melanogaster and Tribolium castaneum support the hypothesis that oenocyte

97 In Tribolium castaneum TcA cells, Trichostatin A, a histone

98 Crystal structures of Tribolium castaneum telomerase reverse transcriptase (tc

99 Here, we determined structures of Tribolium castaneum telomerase reverse transcriptase (TE

100 e crystal structure of 5-MeCITP bound to the Tribolium castaneum telomerase reverse transcriptase rev

101 al Ca(2+)-conducting complex, MCU-EMRE, from Tribolium castaneum to probe ion selectivity mechanisms.

102 w fluorescent transgenic lines in the beetle Tribolium castaneum to show that the EE tissues dynamica

103 ificity in an invertebrate model, the beetle Tribolium castaneum Using controlled evolution experimen

104 o acids in two vitellogenins from the beetle Tribolium castaneum was 0.975, even though the two amino

105 by extensive data from the red flour beetle Tribolium castaneum with its more insect-typical develop

106 d fitness traits using the red flour beetle (Tribolium castaneum) and the tapeworm parasite (Hymenole

107 Using the flour beetle (Tribolium castaneum) in a microcosm experiment, we disen

108 A genetic map of the red flour beetle (Tribolium castaneum) integrating molecular with morpholo

109 The red flour beetle (Tribolium castaneum) is an important model organism for

110 rates and short-germ insects like the beetle Tribolium castaneum) painted a different, very dynamic v

111 menolepis diminuta) in the red flour beetle (Tribolium castaneum) that serves as an intermediate host

112 e blastoderm tissue of the red flour beetle (Tribolium castaneum) tightly adheres in a temporally coo

113 Here we use flour beetles (Tribolium castaneum) to show experimentally that mean ex

114 ene expression patterns in the flour beetle (Tribolium castaneum), the honeybee (Apis mellifera) and

115 erm insects, including the red flour beetle (Tribolium castaneum), the segment-polarity function of w

116 Using a model system, red flour beetles (Tribolium castaneum), we either allowed or constrained e

117 replicates of red flour beetle populations (Tribolium castaneum).

118 ptors were examined in the red flour beetle (Tribolium castaneum): 1) cardioacceleratory peptide 2b (

119 lcholinesterase genes (TcAce1 and TcAce2) in Tribolium castaneum, a globally distributed major pest o

120 ated gene silencing in the red flour beetle, Tribolium castaneum, a species that develops an appendag

121 le genome sequence from the red flour beetle Tribolium castaneum, along with those from other insect

122 we conduct genetics in insects, including in Tribolium castaneum, an important genetic model and agri

123 MCU-EMRE complex from the red flour beetle, Tribolium castaneum, and a cryo-EM structure of the comp

124 ous insect species: Drosophila melanogaster, Tribolium castaneum, and Bombyx mori.

125 onally desiccation-tolerant red flour beetle Tribolium castaneum, and demonstrate its utility by iden

126 lable datasets from Drosophila melanogaster, Tribolium castaneum, Arabidopsis thaliana and C. elegans

127 otic selector genes of the red flour beetle, Tribolium castaneum, are located in a single cluster.

128 In this study, using the red flour beetle, Tribolium castaneum, as a model insect species, we show

129 s and tyrosinases from the red flour beetle, Tribolium castaneum, as well as their developmental patt

130 a backcross family of the red flour beetle, Tribolium castaneum, based largely on sequences from bac

131 In the flour beetle, Tribolium castaneum, ectopic wingless also induced engra

132 odel organisms, such as the red flour beetle Tribolium castaneum, have provided a wealth of insight i

133 The red flour beetle, Tribolium castaneum, is an emerging model organism separ

134 lt capitate antenna of the red flour beetle, Tribolium castaneum, is composed of eleven articles, org

135 how that TcBuster, from the red flour beetle Tribolium castaneum, is highly active in human cells.

136 In beetles, such as Tribolium castaneum, it is the forewings that are modifi

137 terning, but in short-germ insects including Tribolium castaneum, loss of Wnt signaling affects devel

138 We used a model system (Tribolium castaneum, red flour beetles) to test how the

139 e acquired in Diptera, as in the coleopteran Tribolium castaneum, repression of br by E93 is not suff

140 , while other insects, like the flour beetle Tribolium castaneum, retain an ancestral robo2/3 gene.

141 In the red flour beetle Tribolium castaneum, RNA interference (RNAi) has been us

142 In the red flour beetle, Tribolium castaneum, RNA interference studies indicate t

143 ut to describe cellularization in the beetle Tribolium castaneum, the embryos of which exhibit a thin

144 ryonic tissue (serosa) epiboly in the insect Tribolium castaneum, the non-proliferative serosa become

145 In the red flour beetle, Tribolium castaneum, the only currently available system

146 ning of mandibulate mouthparts of the beetle Tribolium castaneum, using RNA interference to deplete t

147 son system derived from the red flour beetle Tribolium castaneum, was shown to be highly active in pr

148 In the red flour beetle, Tribolium castaneum, we have isolated loss-of-function m

149 Using the red flour beetle, Tribolium castaneum, we identify major fitness benefits

150 ng genes in embryos and larvae of the beetle Tribolium castaneum, we provide the first molecular evid

151 As RNAi works well in Tribolium castaneum, we utilized this insect and RNAi to

152 compared these processes in the flour beetle Tribolium castaneum, which develops ventral appendages d

153 eauveria bassiana, and the red flour beetle, Tribolium castaneum, which has a well-documented externa

154 tions of wg and dpp in the red flour beetle, Tribolium castaneum, which retains more ancestral modes

155 ded in Anopheles gambiae, Aedes aegypti, and Tribolium castaneum, while the PF repeats are reduced in

156 Vg) gene expression in the red flour beetle, Tribolium castaneum.

157 gypti and TcBuster from the red flour beetle Tribolium castaneum.

158 copeltus fasciatus, and the red flour beetle Tribolium castaneum.

159 resistance observed in the QTC279 strain of Tribolium castaneum.

160 ursicon receptor (Tcrk) in the model insect, Tribolium castaneum.

161 egulated expression in the red flour beetle, Tribolium castaneum.

162 not in Anopheles gambiae, Apis mellifera, or Tribolium castaneum.

163 analyzed wing development in a coleopteran, Tribolium castaneum.

164 nction of toy and ey in the red flour beetle Tribolium castaneum.

165 ction of these genes in the red flour beetle Tribolium castaneum.

166 genomic information for the red flour beetle Tribolium castaneum.

167 quito Anopheles gambiae and the flour beetle Tribolium castaneum.

168 in a basal holometabolous insect, the beetle Tribolium castaneum.

169 - to late-larval stages of the flour beetle, Tribolium castaneum.

170 he silkmoth Bombyx mori and the flour beetle Tribolium castaneum.

171 el habitat using experimental populations of Tribolium castaneum.

172 sis of the gl orthologue of the flour beetle Tribolium castaneum.

173 c/sc genes in the coleopteran insect species Tribolium castaneum.

174 opeltus fasciatus; and the red flour beetle, Tribolium castaneum.

175 ic model insects Drosophila melanogaster and Tribolium castaneum.

176 secticide resistance in the red flour beetle Tribolium castaneum.

177 is a particularly stressful environment for Tribolium castaneum.

178 at alter embryonic patterning of the beetle, Tribolium castaneum.

179 s underpinning leptophragmata development in Tribolium castaneum.

180 gogenic architecture underlying dispersal in Tribolium castaneum.

181 opment of the short germband model organism, Tribolium castaneum.

182 equired for cell intercalation in the beetle Tribolium castaneum.

183 een targeting GPCRs in the red flour beetle, Tribolium castaneum.

184 cessory gland (MAG) in the red flour beetle, Tribolium castaneum.

185 model and pest insect, the red flour beetle Tribolium castaneum.

186 uropils in the brain of the red flour beetle Tribolium castaneum.

187 s of the larval head in the red flour beetle Tribolium castaneum.

188 a delivery vehicle for dsRNA was assessed in Tribolium castaneum.

189 We identified the dsx homolog (Tcdsx) in Tribolium castaneum.

190 cs in key model systems such as Bombyx mori, Tribolium casteneum, Aedes aegypti, and Anopheles stephe

191 Our investigation in Tribolium (Coleoptera) has revealed that, despite the we

192 he three techniques were applied to identify Tribolium collected from stored samples and samples capt

193 neum (Herbst) and the confused flour beetle, Tribolium confusum Jacquelin du Val, were assessed after

194 of the flour beetles Tribolium castaneum and Tribolium confusum, we show that interspecific competiti

195 Tribolium contains additional Wnt family genes that are

196 k of an embryonic head specification role in Tribolium could be interpreted as a loss of the head seg

197 ligus, and Lepeophtheirus) and some insects (Tribolium, Danaus, Pediculus, and Acyrthosiphon) contain

198 The Tribolium data therefore suggest that multiple origins o

199 tudinal pathways are remarkably conserved in Tribolium, despite it having only two Robos.

200 The complement of primary pair-rule genes in Tribolium differs from Drosophila in that it includes Tc

201 hic populations and 101 individuals, built a Tribolium DNA barcode library, and designed species-spec

202 lular cAMP levels in HEK293 cells expressing Tribolium Dopamine D2-like receptor.

203 we found nine lineages per hemisphere in the Tribolium embryo while Drosophila produces only eight pe

204 In contrast to Drosophila, Tribolium embryos exhibit the short-germ type of develop

205 Tribolium embryos in which dpp had been downregulated ha

206 ion to the maternally loaded primary piRNAs, Tribolium embryos produce secondary piRNAs by the cleava

207 approaches with live fluorescence imaging of Tribolium embryos to make the link between gene function

208 ribe and compare cell and tissue dynamics in Tribolium embryos with wild-type and altered fate maps.

209 sistent expression of fluorescent markers in Tribolium embryos, labeling the chromatin, membrane, cyt

210 ybird, is absent from the dorsal mesoderm of Tribolium embryos.

211 xperimental framework, we discovered several Tribolium enhancers, and assessed the spatiotemporal act

212 These observations suggest that the Tribolium eye is pigmented only by ommochromes, not pter

213 l adaptation in sperm and egg function using Tribolium flour beetles, a warm-temperate-tropical insec

214 ochrome oxidase subunit I (COI) barcodes for Tribolium from 18 geographic populations and 101 individ

215 r to its Drosophila counterpart in size, the Tribolium genes contain fewer introns (with the exceptio

216 and display the tissue expression of related Tribolium genes or homologous Drosophila genes.

217 tleAtlas allows one to search for individual Tribolium genes to obtain values of both total gene expr

218 aster gene identifiers to search for related Tribolium genes.

219 We identified 41 of these genes in the Tribolium genome by using a combination of bioinformatic

220 ree peptides also appear to be absent in the Tribolium genome.

221 tleBase serves as a long-term repository for Tribolium genomic data, and is compatible with other mod

222 We find that Tribolium germband condensation is effected by cell cont

223 activation domain characterize the putative Tribolium gl protein.

224 Tribolium gl transcripts were detected in the developing

225 Here we show that segmentation in Tribolium has phases of variable periodicity during whic

226 For example, Tribolium has retained more ancestral genes involved in

227 Flour beetles of the genus Tribolium have been utilised as informative study system

228 To elucidate the role of Pax6 during Tribolium head development in more detail, we studied he

229 Unlike the ANTC, this region of the Tribolium HOMC contains no additional genes.

230 In Tribolium, homologs of almost all the eight canonical Dr

231 was observed in the genetic black mutants of Tribolium, in which levels of TcADC mRNA were drasticall

232 at least nine neuropeptide genes missing in Tribolium, including the genes encoding the prepropeptid

233 Our analysis of Tribolium indicates that, during insect evolution, genes

234 ipped was demonstrated in the growth zone of Tribolium, indicating that a vertebrate-like segmentatio

235 We find that maternal knockdown of Tribolium innexin7a (Tc-inx7a), an ortholog of the Droso

236 on at both blastoderm and germband stages of Tribolium is based on a segmentation clock.

237 The mxp mutant larval phenotype in Tribolium is consistent with the hypothesis that an ance

238 Development in Tribolium is more representative of other insects than i

239 Our results show that the piRNA pathway in Tribolium is not restricted to the germline, but also op

240 e of prd is conserved between Drosophila and Tribolium; it is required in both insects to activate en

241 We show here that the Tribolium labial appendages also develop as antennae in

242 We find that the Tribolium larval eyes originate at the posterior margin

243 Flour beetles of the genus Tribolium Macleay (Coleoptera: Tenebrionidae) are import

244 As with Apis, Drosophila and Tribolium, Nasonia possesses ion channels predicted to b

245 develop a transformant selection system for Tribolium on the basis of mutant rescue.

246 a loss of the head segmentation function in Tribolium or gain of this function during evolution of f

247 tingly, mutations in Cephalothorax (Cx), the Tribolium ortholog of Scr, transform the labial appendag

248 We analyzed the Tribolium orthologs of Drosophila pair-rule genes, which

249 The Tribolium orthologs of the Drosophila eye-color genes ve

250 m an anteriorly localized messenger RNA, the Tribolium Otd gradient forms by translational repression

251 The periodicity of the Tribolium pair-rule gene interactions reveals components

252 The two Tribolium piRNA pathway effector proteins, Tc-Piwi/Aub a

253 Specifically, we show that the Tribolium primary pair-rule gene, Tc-even-skipped (Tc-ev

254 rther, we demonstrate that expression of the Tribolium proboscipedia ortholog maxillopedia (mxp) is g

255 arison of the function of the Drosophila and Tribolium proneural ac/sc genes suggests that in the Dro

256 This suggests that in Tribolium Rdl, de novo mutations for resistance have ari

257 enriched and functionally significant in the Tribolium rectal complex.

258 ce analysis lead us further to conclude that Tribolium represents an ancestral state of redundant con

259 The Medea system in Tribolium represents an unusual type of intragenomic con

260 BeetleBase will be useful to the Tribolium research community for genome annotation as we

261 BeetleBase is an integrated resource for the Tribolium research community.

262 ly in the lineages leading to Drosophila and Tribolium reveals an unprecedented flexibility in pair-r

263 ng evolutionary questions, as Drosophila and Tribolium segment their blastoderms using the same genes

264 are not required for proper segmentation in Tribolium, segmental expression of Tc-en and Tc-wg is co

265 Drosophila and the beetle Tribolium share extensive dependence on Toll, while repr

266 Our results show that Tribolium so and eya are essential for both larval and a

267 in replicated communities of flour beetles (Tribolium sp.).

268 se controlled, replicated communities of two Tribolium species (T. castaneum and T. confusum) to exam

269 Traditionally, Tribolium species are identified according to the morpho

270 for the rapid and accurate identification of Tribolium species are required, particularly for pest mo

271 he identification of six stored-product pest Tribolium species including T. castaneum, T. confusum, T

272 primers and TaqMan probes for the above six Tribolium species.

273 ters encoding multiple paralogs from several Tribolium-specific microRNA families expressed during a

274 the significant historical contribution that Tribolium study systems have made to the fields of ecolo

275 found in the pair-rule circuit of the beetle Tribolium Taken together, our results suggest that the d

276 In contrast, Ftz from the primitive insect Tribolium (Tc-Ftz) has retained homeotic potential, gene

277 Both TEN and TRAP are absent in the putative Tribolium TERT that has been used as a model for telomer

278 bryonic lineages are significantly larger in Tribolium than they are in Drosophila and contain more i

279 ides insight into short-germ segmentation in Tribolium that may be more generally applicable to segme

280 These include the Medea1 selfish element of Tribolium that spreads via post-zygotic killing.

281 om T. molitor larvae and larvae of the genus Tribolium; thus, they are useful in the analysis of comp

282 review the broad range of studies employing Tribolium to make significant advances in ecology and ev

283 The ability of Tribolium to organize longitudinal axons into three disc

284 c and tissue-specific web-based resource for Tribolium transcriptomics: BeetleAtlas.

285 the population dynamics of the flour beetle Tribolium under laboratory conditions and to establish t

286 In contrast, Tribolium undergoes short germ embryogenesis: the embryo

287 to pattern its dorsoventral axis, the beetle Tribolium utilizes many of the same genes used in flies,

288 om differences in the population genetics of Tribolium versus that of mosquitoes and differences in m

289 we studied the embryonic development of the Tribolium visual system.

290 ed and determined the expression patterns of Tribolium vnd, ind, and msh, and found that they are exp

291 like observations from other insects such as Tribolium, we find the Dorsal gradient maintains a const

292 e role is conserved in the red flour beetle, Tribolium (where legs develop during embryogenesis), yet

293 vnd expression are similar in Drosophila and Tribolium, whereas those that initiate Tc-ind have diver

294 tains fewer immune genes than Drosophila and Tribolium, which may reflect the prominent role played b

295 On the contrary, here we show in the beetle Tribolium, whose development is broadly representative f

296 umber of future research opportunities using Tribolium, with particular focus on how their amenabilit

297 We collected 141 strains of Tribolium worldwide and screened them for resistance.