ライフサイエンスコーパス: UDP-galactose 4-epimerase

1 DR) family, with the closest relationship to UDP-galactose 4-epimerase.

2 nase, galactose-1-P uridylyltransferase, and UDP-galactose 4-epimerase.

3 ound structural homology in Escherichia coli UDP-galactose 4-epimerase.

4 ormation with the 3-dimensional structure of UDP-galactose-4-epimerase.

5 The product of this gene has UDP galactose 4-epimerase activity in both E. coli and Y

6 ive site is reminiscent to that observed for UDP-galactose 4-epimerase, an enzyme that plays a key ro

7 GALE encodes UDP-galactose-4-epimerase, an enzyme of galactose metabo

8 pression of a gene encoding Escherichia coli UDP-galactose 4-epimerase and engineered to facilitate c

9 in genes encoding phosphoglucomutase (pgm), UDP-galactose-4-epimerase, and two other NTHI sialyltran

10 24, Tyr149, and Lys153 in the active site of UDP-galactose 4-epimerase are located in similar positio

11 richia coli dTDP-glucose 4,6-dehydratase and UDP-galactose 4-epimerase are members of the short-chain

12 mes of the pathway, galactose mutarotase and UDP-galactose 4-epimerase, are contained within a single

13 UDP-galactose 4-epimerase catalyzes the conversion of UD

14 UDP-galactose 4-epimerase catalyzes the interconversion

15 UDP-galactose 4-epimerase catalyzes the interconversion

16 UDP-galactose 4-epimerase catalyzes the interconversion

17 UDP-galactose 4-epimerase contains the coenzyme NAD+ bou

18 der can occur due to either galactokinase or UDP-galactose 4-epimerase deficiencies.

19 g of uridine diphosphogalactose 4-epimerase (UDP-galactose 4-epimerase, EC ) and alpha1, 3-galactosyl

20 The enzyme uridine diphosphate (UDP)-galactose-4-epimerase, encoded by GALE, is involved

21 Enzymatic activity of the UDP-galactose-4-epimerase enzyme was severely decreased

22 meters for epimerization of UDP-galactose by UDP-galactose 4-epimerase from Escherichia coli (GalE),

23 UDP-galactose 4-epimerase from Escherichia coli catalyze

24 UDP-galactose 4-epimerase from Escherichia coli contains

25 The enzyme UDP-galactose 4'-epimerase (GALE) catalyses the reversib

26 UDP-galactose 4'-epimerase (GALE) catalyzes the final st

27 UDP-galactose 4'-epimerase (GALE) catalyzes the final st

28 UDP-galactose 4'-epimerase (GALE) catalyzes the intercon

29 UDP-galactose 4'-epimerase (GALE) interconverts UDP-gala

30 galactosemia results from the impairment of UDP-galactose 4'-epimerase (GALE), the third enzyme in t

31 address this knowledge gap, here we examined UDP-galactose 4'-epimerase (GALE), which interconverts t

32 Galactosemia III results from the loss of UDP-galactose 4'-epimerase (GALE), which interconverts U

33 Mechanistically, we identified UDP-galactose-4-epimerase (GalE) as a direct transcripti

34 UDP-galactose-4-epimerase (GALE) is a highly conserved e

35 results from impairment of the human enzyme UDP-galactose-4-epimerase (hGALE).

36 UDP-galactose 4-epimerase is one of three enzymes in the

37 UDP-galactose 4-epimerase plays a critical role in sugar

38 Homology modeling with UDP-galactose-4-epimerase predicts that Asp36 is respons

39 ical bilobal topology observed for all other UDP-galactose 4-epimerases studied thus far.

40 UDP-galactose 4'-epimerase (TbGalE), an enzyme of the Le

41 Unlike UDP-galactose 4-epimerase where the conversion of config

42 o the roles of the corresponding residues in UDP-galactose 4-epimerase, which facilitate the ionizati

43 We characterized mutants defective in UDP-galactose 4-epimerase, which produced a defective li

44 tural comparison of ADP-hep 6-epimerase with UDP-galactose 4-epimerase, which utilizes an NAD(+) cofa