ライフサイエンスコーパス: Vd

1 Vd/Vt is predictable from clinically available data.

2 Vd/Vt was calculated using the Enghoff modification of t

3 core, 13 +/- 3.4 vs. 7.7 +/- 0.8; p = .006) (Vd/Vt, 0.68 +/- 0.07 vs. 0.58 +/- 0.07; p = .009) (EVLWp

4 albumin = 25 g/day + (albumin 1 - albumin 2)(Vd)/days, where albumin 1 and 2 are the serum albumin co

5 of 22.8 hours (range, 24.1 to 30.6 hours), a Vd of 9.4 L (range, 4.4 to 19.5 L), and a CL of 0.32 L/h

6 Body weight also affected Vd(ss) (0.1 l increase of Vd(ss) per kilogram above medi

7 nces were significant when Vc > or = 50% and Vd was compared with Va and Vb (P < 0.05).

8 fferences between Va and Vb and Vc > 50% and Vd were significant (P < 0.05).

9 ttle or no avoidance, strikingly, the Dm and Vd were not engaged, despite similar levels of activatio

10 Total clearance was 9.43 mL/h and Vd(ss) was 9.61 l.

11 urs, CL/F (apparent clearance) 28.9 L/h, and Vd/F (apparent volume) 274 L.

12 In a combined Kd56 and Vd analysis, complete renal responders had longer median

13 =80 mL/min, n = 193 and n = 189 for Kd56 and Vd arms, respectively).

14 l nucleus of the ventral telencephalic area (Vd), the teleost anatomical homologs of the mammalian am

15 max, volume of distribution/bioavailability (Vd/F), and elimination half-life (t(1/2)) were not diffe

16 ve undertaken a comparative study of six (D, Vd, Vv, Dm, Dl, Ppa) periventricular zones (PVZs) harbor

17 equation for Vd/Vt using the clinical data: Vd/Vt = 0.32 + 0.0106 (Paco2 - ETCO2) + 0.003 (RR) + 0.0

18 median and minimum values for model-derived Vd were 6.3, 3.7 and 2.11, respectively.

19 val (PFS) over bortezomib and dexamethasone (Vd) in patients with relapsed/refractory multiple myelom

20 , mean half-life and volume of distribution (Vd) in women were 15 days and 72 mL/kg, respectively, af

21 .0 to 80.0 hours), a volume of distribution (Vd) of 10.9 L (range, 3.1 to 34.5 L), and a clearance (C

22 S-BBBO increases the volume of distribution (Vd) of dye after CED administration, but results in a sh

23 imes increase in the volume of distribution (Vd).

24 eristic curve analysis indicated that EVLWp, Vd/Vt, and extravascular lung water (p = .0005, .009, an

25 rrection for partial volume effect, [11C]FMZ Vd in the body of the epileptogenic hippocampus was redu

26 of [11C]FMZ volume of distribution ([11C]FMZ Vd) obtained in 10 patients with refractory mTLE due to

27 in the [11C]FMZ volume of distribution (FMZ-Vd) before and after correction for partial volume effec

28 cant bilateral reductions of hippocampal FMZ-Vd were detected.

29 s on MRI showed unilateral reductions of FMZ-Vd concordant with the side of the EEG focus.

30 lerosis showed significant reductions of FMZ-Vd in the hippocampus contralateral to the side of the E

31 ts, significant unilateral reductions of FMZ-Vd were found in one of the three patients with bilatera

32 owed significant bilateral reductions of FMZ-Vd, and these were asymmetrical in two.

33 used to construct a predictive equation for Vd/Vt using the clinical data: Vd/Vt = 0.32 + 0.0106 (Pa

34 Pulmonary dead space fraction (Vd/Vt) is an independent predictor of mortality in acute

35 ent score, dead space-tidal volume fraction (Vd/Vt), and EVLWp were all significantly higher on day 1

36 rmacokinetic profile (F, 82%; t(1/2), 5.6 h; Vd, 0.694 L/kg) with good drug penetration in target tis

37 High Vd/Vt was the most consistent gas exchange abnormality i

38 f ventilatory ratio had significantly higher Vd/Vt.

39 There was no difference in Vd/Vt or other physiological outcomes.

40 Newborn single-dose half-life, Vd, and clearance were 30 days, 143 mL/kg, and 4 mL/kg/d

41 study of ARDS, we tested the association of Vd/Vt with ventilatory ratio.

42 ight also affected Vd(ss) (0.1 l increase of Vd(ss) per kilogram above median of 75 kg).

43 56 demonstrated PFS and OS improvements over Vd in RRMM patients regardless of their baseline renal f

44 , which were designated as Pas1c1-Vc, Pas1c1-Vd, and Pas1c1-Ve, respectively.

45 = 0.007), owing to the higher physiological Vd (68 [58.73] % vs. 54 [41.64] %; P = 0.012).

46 text]co2, dead space to tidal volume ratio (Vd/Vt), and arterial to end-tidal CO2 difference were al

47 iate regions and part of the ventral region, Vd/Vc/Vi, and Vv) expressed high levels of AptCB1R trans

48 the serum sampling intervals, respectively; Vd is the volume of distribution (L); and days relates t

49 Failure Assessment score, lung injury score, Vd/Vt, and PaO2/FIO2.

50 primary end point was pulmonary dead space (Vd/Vt) at 6 hours after esophagectomy or before extubati

51 The volume of distribution at steady-state (Vd(ss)) was 700 L/m2 and the clearance was 300 mL/min/m2

52 and volume of distribution at steady-state (Vd(ss)) were investigated.

53 Within all subjects, Vd/Vt correlated with the [Formula: see text]e/[Formula:

54 age was also negatively correlated with TCR Vd + Jd receptor diversity regardless of immune challeng

55 dorsal nucleus of the ventral telencephalon [Vd]), parts of the preoptic area (NPOmg and NPOpc), ento

56 1 ng/mL, the Vd was 3.97 +/- 0.95 L, and the Vd/kg was 0.05 +/- 0.01 L/kg.

57 hours, the Cmax was 2,549 +/- 291 ng/mL, the Vd was 3.97 +/- 0.95 L, and the Vd/kg was 0.05 +/- 0.01

58 rst characterization of an F. nucleatum Type Vd phospholipase class A1 autotransporter (strain ATCC 2

59 ct, track, and characterize the role of Type Vd secreted phospholipases in Gram-negative bacteria.

60 Whereas the role of Type Vd secretion in bacteria remains unidentified, we show t

61 cies with high particle deposition velocity (Vd) values, currently under-parameterised in most modell

62 , and lateral nucleus of the area ventralis [Vd, Vv, Vc, and Vl, respectively]), as well as preoptic

63 partment 1, the initial distribution volume (Vd) of the antibody, which included serum.

64 (kloss); and the tracer distribution volume (Vd), which is an index of dopamine storage capacity.

65 Here we evaluated Kd56 vs Vd by baseline renal function in a post hoc exploratory

66 d 77.1% vs 65.9% for those receiving Kd56 vs Vd, respectively.

67 5% CI, 8.0-22.6) for those receiving Kd56 vs Vd, respectively.

68 CI, 0.434-0.827) for those receiving Kd56 vs Vd, respectively; median overall survival (OS) was 42.1

69 regional injuries: equation [see text] where Vd is the volume of lung irradiated to dose d, and Rd is

70 sed diffuse endocapillary proliferation, WHO Vd).

71 Ventilatory ratio positively correlated with Vd/Vt.

72 Ventilatory ratio correlates well with Vd/Vt in ARDS, and higher values at baseline are associa

73 Relative to acute withdrawal, Vd significantly decreased in the right ventral and dors

74 nalysis of the binding potential [Bmax/(Kd x Vd)] using the assumption of equal partition coefficient