ライフサイエンスコーパス: X-chromosome gene

1 to synonymous substitution rates (dN/dS) on X-chromosome genes.

2 and XX cells may have a higher dose of some X-chromosome genes.

3 ons in the fly for 2-fold activation of male X-chromosome genes.

4 lasia congenita (AHC) critical region on the X chromosome, gene 1] is an orphan nuclear receptor that

5 y the significant upregulation of the female X chromosome genes and a correlated female-specific leth

6 x (phosphate regulating endopeptidase on the X chromosome) gene and human XLH-OA.

7 re ill-defined and presumptively ascribed to X-chromosome genes and sex hormones(1).

8 ces have suggested that although single-copy X Chromosome genes are conserved between species, most a

9 Currently only three X chromosome genes are considered of moderate-definitive

10 In mammals, X chromosome genes are present in one copy in males and

11 omparative genomics, we find that these same X-chromosome genes are exceptionally poorly conserved in

12 This demonstration of an X chromosome gene as a disease susceptibility factor in

13 n exon 1 of the human androgen receptor (AR) X chromosome gene assay (HUMARA) has been used to determ

14 Six of 783 non-pseudoautosomal region (PAR) X-chromosome genes (ATRX, CNKSR2, DDX3X, KDM5C, KDM6A, a

15 or detecting the transcripts of 2 additional X-chromosome genes: Bruton tyrosine kinase (BTK) and 4-a

16 further deletions and duplications affecting X chromosome genes but without apparent disease conseque

17 A subset of X-chromosome genes can escape X-inactivation, which woul

18 of existing genes contribute to the unusual X chromosome gene content.

19 on of Y-chromosomes across fly species.While X-chromosome gene content tends to be conserved, Y-chrom

20 the-first) is required for the regulation of X chromosome gene dosage compensation in Drosophila male

21 We present a comprehensive view of X chromosome gene dosage in hiPSCs and implicate a direc

22 The gene-wise landscape of X chromosome gene dosage remains unresolved in female hi

23 s are hormonally driven and not explained by X chromosome gene dosage.

24 X-chromosome gene dosage is compensated by a specialized

25 SLE susceptibility is partly explained by an X chromosome gene-dose effect.

26 sex chromosome genes, a small percentage of X chromosome genes escape X inactivation and have higher

27 X chromosome gene expression (29 genes), adjusted for ag

28 In contrast with cognition, X chromosome gene expression (3 genes), adjusted for age

29 Dosage compensation, the equalized X chromosome gene expression between males and females i

30 s in early embryonic development, equalizing X chromosome gene expression between males and females.

31 This study concisely shows the value of X chromosome gene expression in T cell regulation of aut

32 The main analysis examined whether X chromosome gene expression measured by RNA sequencing

33 Whether X chromosome gene expression was associated with neurofi

34 higher order chromosome structure and proper X chromosome gene expression.

35 f the C. elegans mitotic machinery regulates X chromosome gene expression.

36 occurring human model for the study of both X-chromosome gene expression and androgen on brain devel

37 ial process of dosage compensation equalizes X-chromosome gene expression between Caenorhabditis eleg

38 We also show that the DCC balances X-chromosome gene expression between sexes by controllin

39 , and mammals, dosage compensation equalizes X-chromosome gene expression between the sexes through c

40 ers new insight into the relationships among X-chromosome gene expression, neuroanatomy, and cognitiv

41 young male with a hemizygous mutation in the X-chromosome gene FIGF (c.352 G>A) associated with early

42 ty for advancing scientific knowledge of how X chromosome gene imprinting, epigenetic factors, hormon

43 The uncommon and variable reactivation of X chromosome genes in female hiPSCs can provide insight

44 We sequenced introns from 22 X chromosome genes in M and S from two locations of West

45 sage also affects expression of genes on the X chromosome, genes influenced by sex steroid hormone, a

46 ation that loss of function of 1% or more of X-chromosome genes is compatible with apparently normal

47 E-1 transposons are strongly enriched on the X chromosome, genes located on the X chromosome are also

48 d on the cell surface because of an acquired X-chromosome gene mutation.

49 regulation due to missense mutations in the X chromosome gene, NKAP.

50 ts have been linked to male infertility, and X-chromosome genes OPN1LW and OPN1MW linked to eye disor

51 ome phenotype and, thus, demonstrate that an X chromosome gene (or genes) regulates HSC replication,

52 on detection of exonic polymorphisms of the X chromosome genes p55 and G6PD using rtPCR-LDR.

53 Loss-of-function mutations in the X chromosome gene PIGA lead to phosphatidylinositol glyc

54 that males and females have equal amounts of X-chromosome gene products.

55 ed on quantitative expression of polymorphic X chromosome genes (qTCA) and found no evidence of clona

56 Chromosome segregation and X-chromosome gene regulation in Caenorhabditis elegans s

57 The X-chromosome gene regulatory process called dosage compe

58 and report a dramatic underrepresentation of X-chromosome genes showing high relative expression in m

59 m cell elimination associated with defective X chromosome gene silencing and sex chromosome condensat

60 e identified the genomic dosage of Kdm5c, an X chromosome gene that escapes X chromosome inactivation

61 t the histone demethylase UTX, encoded by an X chromosome gene that escapes XCI, contributes to sex d

62 c traits is through sex-biased expression of X chromosome genes that escape X inactivation.

63 This suggests an alternative X-chromosome gene, that escapes inactivation, is respons

64 Loss-of-function mutations of the X-chromosome gene UPF3B cause male neurodevelopmental di

65 The X-chromosome gene USP9X encodes a deubiquitylating enzym

66 blood cell disorder due to mutations of the X-chromosome gene WASP (Wiskott-Aldrich syndrome protein

67 ch syndrome (WAS) arises from defects of the X-chromosome gene WASP.

68 We show that X chromosome genes with male-biased expression are under