ライフサイエンスコーパス: abruption

1 uteroplacental dysfunction (e.g., placental abruption).

2 l-for-gestational-age infants, and placental abruption).

3 ) in the first trimester had higher rates of abruption.

4 its distribution under abruption to without abruption.

5 ith spontaneous conception without placental abruption.

6 irth, fetal growth restriction, or placental abruption.

7 al mortality risks associated with placental abruption.

8 e pregnancy may benefit from reduced risk of abruption.

9 ng may influence the recurrence of placental abruption.

10 of the fetal membranes (PPROM) to placental abruption.

11 lowest) had a 25-fold higher mortality with abruption.

12 y that is punctuated by microbial population abruptions.

13 cell-expressed tissue factor often accompany abruptions.

14 0%; RR, 1.53 [95% CI, 1.45-1.61]), placental abruption (1.6% vs 0.9%; RR, 1.72 [95% CI, 1.54-1.92]),

15 R of 1.34 (95% CI: 1.26, 1.43) for placental abruption, 1.21 (95% CI: 1.18, 1.23) for preterm deliver

16 as associated with higher aHRs for placental abruption, 1.62 (95% CI: 1.47, 1.78); preterm delivery,

17 mbranes (23%), preeclampsia (18%), placental abruption (11%), cervical incompetence (5%), and fetal i

18 Exposures were: 1) placental abruption, 2) preterm preeclampsia (<34 weeks of gestati

19 sted RR, 1.10; 95% CI, 0.99-1.21), placental abruption (adjusted RR, 1.01; 95% CI, 0.84-1.21), fever

20 Risk factors for abruption among singleton and twin births, respectively,

21 contrast risk factor profiles for placental abruption among singleton and twin gestations.

22 The risks of placental abruption among spontaneous and ART conceptions were 11

23 tion between cigarette smoking and placental abruption and a weak association with placenta previa bu

24 Placental abruption and cardiovascular disease (CVD) have common e

25 ed women were at increased risk of placental abruption and cesarean delivery, and their infants were

26 suggested increased risks such as placental abruption and cesarean delivery, the findings remained i

27 We estimated associations between abruption and coronary heart disease (CHD) and stroke.

28 Placental abruption and excess thrombin generation elicit preterm

29 We examined the association between abruption and newborn outcomes.

30 Risks of mortality among abruption and nonabruption births were 102.7 and 6.2 per

31 ks of combined CVD morbidity-mortality among abruption and nonabruption groups were 16.7 and 9.3 per

32 and our knowledge of the association between abruption and perinatal and neonatal outcomes.

33 The individual effects of placental abruption and placenta previa on the risk of SIDS did no

34 n and pregnancy complications (eg, placental abruption and preeclampsia), which increase the risk of

35 Risks of placental abruption and preterm delivery in ART conception compare

36 eling about the increased risks of placental abruption and preterm delivery.

37 pregnancy complications, including placental abruption and stillbirth, are at increased risk of futur

38 o intrauterine growth restriction, placental abruption and stillbirth.

39 were IPD, defined as preeclampsia, placental abruption, and birth of a neonate small for gestational

40 m labor, preterm membrane rupture, placental abruption, and cervical insufficiency) and abnormal plac

41 or premature rupture of membranes, placental abruption, and cervical insufficiency.

42 outcomes of preterm birth, PPROM, placental abruption, and pre-eclampsia aggregate in families, whic

43 7.5-8.8) for preterm birth, PPROM, placental abruption, and pre-eclampsia, respectively).

44 .4-4.8), for preterm birth, PPROM, placental abruption, and pre-eclampsia, respectively).

45 ture rupture of membranes (PPROM), placental abruption, and pre-eclampsia.

46 mall-for-gestational-age delivery, placental abruption, and pregnancy loss increase a woman's risk of

47 m birth, fetal growth restriction, placental abruption, and stillbirth in future pregnancies, and a p

48 ies comprising 6,325,152 pregnancies, 69,759 abruptions, and 49,265 CHD and stroke cases.

49 ssociated with CD after labor were placental abruption (aOR, 12.96; 95% CI, 2.85-59.07) and pregestat

50 Although pregnancies complicated by abruption are often delivered through an obstetrical int

51 as preterm birth, preeclampsia and placental abruption, are common, with acute and long-term complica

52 1.31) and antepartum hemorrhage or placental abruption (aRR, 1.48; 95% CI, 1.03-2.14) were associated

53 on (aRR, 1.85; 95% CI, 1.43-2.29), placental abruption (aRR, 1.68; 95% CI, 1.18-2.38), induction (aRR

54 ry was substantially increased even for mild abruptions (aRR for 25% separation, 5.5; 95% CI, 4.2-7.3

55 ivity analyses, there was a direct effect of abruption associated with increased neonatal risks.

56 ssion in term decidual cells may explain how abruption-associated PPROM promotes decidual neutrophil

57 ses that can degrade extracellular matrix in abruption-associated PPROM, we examined whether decidual

58 asts, promoting fetal membrane weakening and abruption-associated PPROM.

59 decidual neutrophil infiltration complicates abruption-associated PPROM.

60 Thus, abruption-associated PTD is initiated by functional prog

61 assessed via immunohistochemical staining in abruption-associated PTD versus gestational-age matched

62 p-ERK1/2, and is thus one pathway initiating abruption-associated PTD.

63 mulas presented in a 2011 paper on placental abruption by Ananth and VanderWeele (Am J Epidemiol.

64 Due to the increasing degree of ecological abruption caused by human influences many advocate that

65 atal mortality was 119 per 1,000 births with abruption compared with 8.2 per 1,000 among all other bi

66 htly higher prevalence of placenta previa or abruption compared with the control group (1.6% [1241] v

67 CSF-2 immunoreactivity was higher in abruption-complicated or idiopathic PTB specimens versus

68 , idiopathic preterm birth (PTB; n = 8), and abruption-complicated pregnancies (n = 8) were immunosta

69 performed in placentas obtained after overt abruption (decidual hemorrhage) with or without PPROM an

70 luding gestational hypertension, stillbirth, abruption, delivery of small for gestational age neonate

71 Placental abruption (early separation of the placenta) is associat

72 Because abruptions elicit intense decidua-enhanced thrombin prod

73 hese pathways collectively lead to placental abruption, fetal demise, and female sterility, thereby p

74 risk of preeclampsia or eclampsia, placental abruption, fever, preterm birth, preterm premature ruptu

75 In the abruption group, 14.3% of neonates were growth restricte

76 conceived using ART and developed placental abruption had a greater risk of preterm delivery compare

77 In this cohort, placental abruption had a profound impact on stillbirth, preterm d

78 nd fetal vascular malperfusion and placental abruption, have an important role in asphyxia and fetal

79 in the third trimester had a higher rate of abruption (hazard ratio (HR) = 1.68, 95% confidence inte

80 ID incidence rates increased with placental abruption (HR = 2.8, 95% CI: 2.3, 3.5), preterm preeclam

81 th premature rupture of membranes, placental abruption, hypertensive disorders of pregnancy, amniotic

82 emoval of women with HCA-positive placentas, abruption, hypertensive disorders, or obesity.

83 (ppb), 26-29 ppb, and 30 ppb) with placental abruption in a prospective cohort study of 685,908 pregn

84 pertension (RR = 2.34) were risk factors for abruption in singleton births but not in twin births.

85 rs found that, among women without placental abruption in the first pregnancy, smoking was associated

86 and second pregnancies and risk of placental abruption in the second pregnancy.

87 moking was associated with increased risk of abruption in the second pregnancy; however, this effect

88 This suggests that abruption in twins may result from different pathophysio

89 in production, we examined the regulation of abruption-induced neutrophil infiltration.

90 xaminations, including evidence of placental abruption, infarction, hypoxia, decidual vasculopathy, o

91 Placental abruption is an uncommon obstetric complication associat

92 potential additive risk of ART and placental abruption is needed.

93 The observation that the recurrence of abruption is substantially increased regardless of chang

94 The authors conclude that abruption is twice as likely to occur in twins as in sin

95 n and abruption suggests that the origins of abruption lie at least in midpregnancy and perhaps even

96 ngs, and there is accumulating evidence that abruption may be associated with future CVD.

97 en with pregnancies complicated by placental abruption may benefit from postpartum screening or thera

98 licated by severe preeclampsia and placental abruption.METHODSWe analyzed the placenta for the presen

99 We conducted a bias analysis to account for abruption misclassification, selection bias, and unmeasu

100 ot related to stillbirth caused by placental abruption, obstetric conditions, or infection.

101 Following blunt trauma abruption of the placenta is the more common cause of fe

102 ure to inhaled corticosteroids and placental abruption on low birth weight mediated by prematurity.

103 irect (preterm delivery-mediated) effects of abruption on mortality were 10.18 (95% confidence interv

104 to examine the extent to which the effect of abruption on perinatal mortality is mediated through pre

105 The total effect risk ratio (RR) of abruption on perinatal mortality was 5.4 (95% CI, 4.6-6.

106 of mothers of controls had either placental abruption or placenta previa during the index pregnancy.

107 ine whether placental abnormality (placental abruption or placental previa) during pregnancy predispo

108 rth due to placental dysfunction, defined as abruption or unexplained stillbirth associated with grow

109 ampsia (OR 2.7; 95% ICI, 2.5-3.0), placental abruption (OR 1.8; 95% ICI, 1.4-2.3), preterm birth (OR

110 ), in the absence of preeclampsia, placental abruption, or fetal growth restriction.

111 at less than 35 weeks' gestation, placental abruption, or fetal or neonatal death.

112 (SGA) newborn (<10th percentile), placental abruption, or pregnancy loss >20 weeks.

113 7 weeks as competing causal mediators of the abruption-perinatal mortality association.

114 high risk of perinatal death associated with abruption persisted.

115 he distinct pattern of results for placental abruption, placenta previa, and uterine bleeding of unkn

116 ing as a potential risk factor for placental abruption, placenta previa, and uterine bleeding of unkn

117 rtly explained the associations of placental abruption, preeclampsia, or SGA with ID.

118 nfection, antepartum hemorrhage or placental abruption, premature rupture of membranes, induction of

119 oids may modestly increase risk of placental abruption, preterm birth and SGA, but they do not appear

120 pertensive disorders of pregnancy, placental abruption, preterm birth, gestational diabetes mellitus,

121 For placental abruption, preterm delivery, small for gestational age (

122 riage, earlier gestation at birth, placental abruption, pulmonary embolism, postpartum haemorrhage, m

123 m ITs; GR was higher in IT than DCs, with no abruption-related changes in either cell type; p-ERK1/2

124 -induced fetal membrane weakening, eliciting abruption-related PPROM and PTB.

125 smoked had a twofold increase in the risk of abruption (relative risk = 2.05, 95% confidence interval

126 confidence interval: 6.4, 9.8) and placental abruption (relative risk = 6.6, 95% confidence interval:

127 tients had both ART conception and placental abruption (RERI, 2.0; 95% CI, 0.5-3.5).

128 Pregnancies complicated by abruption result in increased frequency of perinatal dea

129 daily demonstrated a dose-response trend for abruption risk in singletons and twins.

130 on with number of cigarettes smoked daily on abruption risk.

131 96, 95% CI 1.35-2.86; I(2) = 92%), placental abruption (RR 3.20, 95% CI 2.20-4.65; I(2) = 2%), delive

132 presentation of placenta praevia, placental abruption, ruptured uterus, antepartum haemorrhage (odds

133 primary outcome was a composite of placental abruption, stillbirth, neonatal intensive care unit admi

134 nd fetal vascular malperfusion and placental abruption, substantially contributed to these deaths.

135 associated with elevated rates of placental abruption, suggesting that these exposures may be import

136 he link between fetal growth restriction and abruption suggests that the origins of abruption lie at

137 her cell type; p-ERK1/2 was higher in DCs in abruption than control decidua, with total ERK 1/2 uncha

138 almost nine times as likely to be born with abruption than those in the heaviest (> or =90%) birth w

139 Placental abruption, the premature placental separation, confers i

140 Among women with a prior abruption, the risk of repeating abruption was increased

141 type was shifted from its distribution under abruption to without abruption.

142 ew York), rather than the paper on placental abruption, to carry out their direct and indirect effect

143 cluding small for gestational age, placental abruption, transfer to neonatal intensive care, and 5-mi

144 unostaining for PR was lower in DC nuclei in abruption versus control decidua and was absent from ITs

145 The prevalence of abruption was 0.9% (n = 6,025).

146 The incidence of abruption was 1 % (n = 530).

147 founders, the adjusted OR (AOR) of placental abruption was 1.42 (95% CI, 1.34-1.51) in ART pregnancie

148 Incidence of abruption was 1.6% (n = 3,619).

149 livery based on ART conception and placental abruption was also assessed.

150 Abruption was associated with an 8.9-fold (95% confidenc

151 Abruption was associated with an elevated risk of newbor

152 Abruption was associated with higher mortality from CHD

153 The high mortality with abruption was due, in part, to its strong association wi

154 ith a prior abruption, the risk of repeating abruption was increased irrespective of smoking habits.

155 Placental abruption was indicated in 9.9 per 1,000 pregnancies, wh

156 Abruption was more likely to occur among smokers with ch

157 Abruption was recorded in 5.9 per 1,000 singleton births

158 Abruption was recorded in 6.5 per 1,000 births.

159 for Safe Labor data (n = 203 990; 1.6% with abruption), we applied a potential outcomes-based mediat

160 rth proportions among women with and without abruption were 39.6% and 9.1 %, respectively, yielding a

161 Women who suffered abruption were at 2.65-fold (95% CI: 1.55, 4.54; I2 = 85

162 ery; 55% of the excess perinatal deaths with abruption were due to early delivery.

163 Direct effects attributable to abruption were examined by conditioning on intermediates

164 percentile in the third trimester, rates of abruption were increased with both PM2.5 and nitrogen di

165 Abruptions were associated with a marked decidual neutro

166 eath, fetal growth restriction, or placental abruption who had been referred within the 12th gestatio

167 The authors explored the associations of abruption with fetal growth restriction, preterm deliver

168 tocytes, vacuolar changes, and mitochondrial abruption, with absence of anoikic nuclei.