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1 ring oogenesis and female meiosis is usually acentrosomal.
3 most cell types, oocytes of many species are acentrosomal and must organize spindles in their absence
5 plant cortical microtubule array is a unique acentrosomal array that is essential for plant morphogen
7 organized by imaging microtubule dynamics in acentrosomal basal cytoplasts derived from these cells.
8 meiosis I in mouse oocytes, formation of the acentrosomal bipolar spindle takes 3-4 h, and stabilizat
11 id not alter already-formed Golgi complexes, acentrosomal cells fail to reassemble an integral comple
17 ell-free extracts and experimentally derived acentrosomal cells, randomly oriented microtubules (MTs)
25 PLK-1 as a key player that promotes faithful acentrosomal meiosis in oocytes and demonstrates that it
27 the length and maintaining bipolarity of the acentrosomal meiotic spindle and in promoting the contac
28 required for the proper organization of the acentrosomal meiotic spindle in Drosophila melanogaster
33 yeast, nuclear-independent, self-organized, acentrosomal microtubule arrays are structurally and fun
35 rosome function and reveal a multi-component acentrosomal microtubule assembly pathway to establish i
36 , although Nek2B is not required to organize acentrosomal microtubule asters, we show that addition o
37 sin network interacts with the minus ends of acentrosomal microtubule bundles through the cytolinker
39 is an essential regulator of centrosomal and acentrosomal microtubule formation, yet its structure is
40 organization regulates the role of Golgi in acentrosomal microtubule growth in dendrites and in dend
44 al. demonstrate that Golgi outposts mediate acentrosomal microtubule nucleation and reveal it is cru
46 hese results identify a direct mechanism for acentrosomal microtubule nucleation within neurons and r
47 h is known about the structures that promote acentrosomal microtubule nucleation, less is known about
50 caused aberrant PLK1 aggregation that led to acentrosomal microtubule-organizing center (aMTOC) forma
51 satellite organelle that can function as an acentrosomal microtubule-organizing center (MTOC), nucle
54 nized independently of a centrosome, but how acentrosomal microtubules arrays form and whether they a
56 We find that inactivating TRIM37 improves acentrosomal mitosis because TRIM37 prevents PLK4 from s
57 rgery, vertebrate somatic cells form bipolar acentrosomal mitotic spindles, but the fate of these cel
58 dividual microtubules form stable, polarized acentrosomal MT arrays spanning the axon and dendrite to
61 al centrosome system, which is distinct from acentrosomal oocyte meiosis, but its specific regulatory
67 on pathways from chromatin, spindle MTs, and acentrosomal poles all contribute to robust bipolar spin
69 or Nek6 function did not induce formation of acentrosomal poles, meaning that multipolar spindles wer
70 ugmin-independent MT nucleation process from acentrosomal poles, which becomes increasingly active ov
71 ein is required to maintain the integrity of acentrosomal poles; removal of dynein from bipolar spind
72 that produces a bipolar structure during the acentrosomal process of oocyte meiotic spindle assembly.
73 that EDE1, but not AUG8, is associated with acentrosomal spindle and phragmoplast MT arrays in patte
77 ontrast, elevated TRIM37 expression inhibits acentrosomal spindle assembly through a distinct mechani
79 This screen identified 197 genes involved in acentrosomal spindle assembly, eight of which had no pre
80 hibition, whereas high TRIM37 levels inhibit acentrosomal spindle assembly, leading to mitotic failur
82 oocyte-specific function of kinetochores in acentrosomal spindle bipolarization in mice, and provide
83 is showed robust microtubule assembly of the acentrosomal spindle but frequent chromosome misalignmen
87 so required for establishing and maintaining acentrosomal spindle organization and for preventing exc
88 GSK3 beta) were found to be enriched at both acentrosomal spindle poles and the kinetochore region.
89 equired for the formation and maintenance of acentrosomal spindle poles in extracts prepared from Xen
92 gregation occurs in Drosophila oocytes on an acentrosomal spindle, which raises interesting questions
94 cks centrosomes, but the mechanisms by which acentrosomal spindles are organized and function are lar
96 s undergo mitotic arrest with barrel-shaped, acentrosomal spindles during the rapid cycles of syncyti
97 s undergo mitotic arrest with barrel-shaped, acentrosomal spindles during the rapid S-M cycles of syn
98 ess in Caenorhabditis elegans, detailing how acentrosomal spindles form and revealing mechanisms requ
99 e not required for chromosome segregation on acentrosomal spindles in Caenorhabditis elegans oocytes,
100 a timely manner to promote elongation of the acentrosomal spindles that segregate homologous chromoso
101 (a microtubule-plus-end binding protein) in acentrosomal spindles, we also demonstrate that the spin