ライフサイエンスコーパス: acetylglucosaminidase

1 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase).

2 function of the lysosomal hydrolase alpha-N-acetylglucosaminidase.

3 tic transglycosylases but rather as a beta-N-acetylglucosaminidase.

4 , BgaA, a beta-galactosidase, and StrH, an N-acetylglucosaminidase.

5 pecificity expected of the processing beta-N-acetylglucosaminidase.

6 cture used to confirm that SleL acts as an N-acetylglucosaminidase.

7 trated that ACS activity co-localized with N-acetylglucosaminidase.

8 c hydrolases, a chitodextrinase and a beta-N-acetylglucosaminidase.

9 ve cloned the cDNA and gene encoding alpha-N-acetylglucosaminidase.

10 ases but also contains a subfamily of beta-N-acetylglucosaminidases.

11 ficantly greater in the presence of beta-d-N-acetylglucosaminidase (410 +/- 60%, p < 0.01).

12 utation in the gene (NAGLU) encoding alpha-N-acetylglucosaminidase, a lysosomal enzyme required for t

13 that the satellites are the products of an N-acetylglucosaminidase activity that differs from the atl

14 genous levels of specific, processing beta-N-acetylglucosaminidase activity were significantly reduce

15 disorder caused by the deficiency of alpha-N-acetylglucosaminidase activity, leading to increased lev

16 olase family associated with peptidoglycan N-acetylglucosaminidase activity, suggesting that T6S pept

17 2 as chemoattractants and inducers of beta-N-acetylglucosaminidase activity.

18 N-Acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, also known as "uncovering" enzyme

19 hey increase the levels of defective alpha-N-acetylglucosaminidase and correct its proper sorting tow

20 ve developed an assay system for endo-beta-N-acetylglucosaminidase and glycoamidase (PNGase), using E

21 They were totally deficient in alpha-N-acetylglucosaminidase and had massive accumulation of he

22 We demonstrate that Acm2 is an N-acetylglucosaminidase and identify the pattern of O-glyc

23 GLU gene, resulting in deficiency of alpha-N-acetylglucosaminidase and lysosomal accumulation of hepa

24 beta-GlcNAc moiety by treatment with beta-N-acetylglucosaminidase and selective extension of the oth

25 gene lpqI, encodes an authentic NagZ beta-N-acetylglucosaminidase and that it is essential for PG-de

26 ne with (Man(9)GlcNAc(2))Asn for endo-beta-N-acetylglucosaminidase and the other with Ala-Ser-Phe-(Ma

27 acid sequence comparisons, the novel beta-N-acetylglucosaminidase appears to be conserved in all 12

28 In Enterococcus faecalis, the N-acetylglucosaminidase AtlA plays a predominant role in c

29 ll-separating activity of BslO, a putative N-acetylglucosaminidase bearing three N-terminal S-layer h

30 Drug inhibition of OGT and OGA (N-acetylglucosaminidase) blocked transcription during prei

31 lcNAc from proteins (peptide O-GlcNAc-beta-N-acetylglucosaminidase), can be used to increase O-GlcNAc

32 Endo-beta-N-acetylglucosaminidase completely removed the radiolabel

33 Alpha-N-acetylglucosaminidase deficiency (mucopolysaccharidosis

34 The phenotype of the alpha-N-acetylglucosaminidase-deficient mice is sufficiently sim

35 N-Acetylglucosamine-1-phosphodiester alpha-N-Acetylglucosaminidase (EC 3.1.4.45; phosphodiester alpha

36 us suggestion that the broad-spectrum beta-N-acetylglucosaminidase encoded by the SfGlcNAcase-3/SfHex

37 297 by the streptococcal enzyme endo-beta-N-acetylglucosaminidase (EndoS) induced a dominant suppres

38 otypes secrete two multi-modular endo-beta-N-acetylglucosaminidases, EndoS and EndoS2, that specifica

39 ical synthesis was combined with endo-beta-N-acetylglucosaminidase (ENGase) catalysis to allow the co

40 modifications are generated when endo-beta-N-acetylglucosaminidase (ENGase) cleaves N-linked glycans.

41 EndoBT-3987 is a key endo-beta-N-acetylglucosaminidase (ENGase) that initiates the degrad

42 aiotaomicron, encoding a surface endo-beta-N-acetylglucosaminidase (ENGase), BT3987.

43 The endo-beta-N-acetylglucosaminidases (ENGases) are an enzyme class (EC

44 nzymatic synthesis using engineered endo-B-N-acetylglucosaminidases (ENGases) has been used extensive

45 de species secrete single-domain endo-beta-N-acetylglucosaminidases (ENGases) that specifically bind

46 Endo-beta-N-acetylglucosaminidases (ENGases) that specifically hydro

47 r oxazolines and mutant forms of endo beta-N-acetylglucosaminidases (ENGases).

48 III B) is caused by a deficiency of alpha-N-acetylglucosaminidase enzyme (Naglu), leading to accumul

49 cted protein sequence is unique among beta-N-acetylglucosaminidases excepting Cht60, recently cloned

50 lases comprise an endoenzyme, and the beta-N-acetylglucosaminidase, ExoI, reported here.

51 Endo-beta-N-acetylglucosaminidase F(3) cleaves the beta(1-4) link be

52 r Flavobacterium meningosepticum endo-beta-N-acetylglucosaminidases F2 and F3.

53 ng peptide : N-glycosidase F and endo-beta-N-acetylglucosaminidase F3 resulted in the formation of cr

54 can be either trimmed by a processing beta-N-acetylglucosaminidase (FDL) to produce paucimannosidic N

55 The endo-beta-N-acetylglucosaminidase from Arthrobacter protophormiae (E

56 ansglycosylation activity of the endo-beta-N-acetylglucosaminidase from Arthrobacter protophormiae (E

57 on a representative member, the Nag3 beta-N-acetylglucosaminidase from Cellulomonas fimi, we now sho

58 Endo-beta-N-acetylglucosaminidase from Streptococcus pneumoniae (End

59 ansglycosylation activity of the endo-beta-N-acetylglucosaminidases from Arthrobacter protophormiae (

60 companying papers describe two unique beta-N-acetylglucosaminidases from Vibrio furnissii.

61 t allows sequential isolation of endo-beta-N-acetylglucosaminidase H (EC 3.2.1.96)-released high-mann

62 immunoprecipitates digested with endo-beta-N-acetylglucosaminidase H (Endo H), indicate that ZP3 is s

63 paragine amidase (PNGase F)- and endo-beta-N-acetylglucosaminidase H (Endo H)-released oligosaccharid

64 ty control but can be removed using endo-B-N-acetylglucosaminidase H (Endo H).

65 control but can be removed using endo-beta-N-acetylglucosaminidase H (Endo H).

66 Using endo-beta-N-acetylglucosaminidase H and peptide:N-glycosidase F sens

67 rylated, but it was sensitive to endo-beta-N-acetylglucosaminidase H and to glycopeptidase A.

68 ion to functional heterogeneity, endo-beta-N-acetylglucosaminidase H digestion and glycomic profiling

69 etry, brefeldin A treatment, and endo-beta-N-acetylglucosaminidase H digestion suggested that glycosy

70 ked oligosaccharides released by endo-beta-N-acetylglucosaminidase H from Schizosaccharomyces pombe g

71 action of Streptomyces plicatus endo-beta-N-acetylglucosaminidase H on RNase B.

72 Both proteins remained endo-beta-N-acetylglucosaminidase H sensitive, indicating that the C

73 secreted enzyme were cleaved by endo-beta-N-acetylglucosaminidase H, with phosphate present on the s

74 an bind GlcNAc through the N-terminal beta-N-acetylglucosaminidase homology domain.

75 acetylglucosaminyltransferase and O-linked N-acetylglucosaminidase in an antagonistic manner.

76 re potent and selective inhibitors of beta-N-acetylglucosaminidases in the submicromolar range.

77 absence of this specific, processing beta-N-acetylglucosaminidase is a key factor distinguishing the

78 age disorder caused by deficiency of alpha-N-acetylglucosaminidase; it is characterized by profound m

79 Identified herein as an N-acetylglucosaminidase, LytB is involved also in coloniza

80 such as leucine aminopeptidase (LAP), beta-N-acetylglucosaminidase (NAG), their sum (N(acq)), urease

81 this route for prenatal delivery of alpha-N-acetylglucosaminidase (Naglu) enzyme into the enzyme-def

82 erotype 2/5 (rAAV2/5) encoding human alpha-N-acetylglucosaminidase (NAGLU) plus immunosuppressive the

83 use is mutation in the gene encoding alpha-N-acetylglucosaminidase (NAGLU), deficiency of NAGLU, and

84 caused by a deficiency of lysosomal alpha-N-acetylglucosaminidase (NAGLU).

85 igns caused by deficient activity of alpha-N-acetylglucosaminidase (NAGLU, EC 3.2.1.50).

86 Together with the exo-B-N-acetylglucosaminidase NagZ and the exo-muramoyl-l-alanin

87 The N-acetylglucosaminidase NagZ of Pseudomonas aeruginosa cat

88 ied transgenic mice that over express beta-N-acetylglucosaminidase (O-GlcNAcase), an enzyme that cata

89 rase (OGT), which adds the sugar, and beta-N-acetylglucosaminidase (O-GlcNAcase), which hydrolyzes it

90 f N-acetylglucosamine is regulated by beta-N-acetylglucosaminidase (O-GlcNAcase), which was previousl

91 ther characterize the recently cloned beta-N-acetylglucosaminidase, O-GlcNAcase.

92 gene encodes the specific, processing beta-N-acetylglucosaminidase of Drosophila melanogaster.

93 The beta-N-acetylglucosaminidase of Escherichia coli was found to h

94 -fdl encodes the specific, processing beta-N-acetylglucosaminidase of S. frugiperda and validate our

95 ucosaminyltransferase) and removal (O-beta-N-acetylglucosaminidase) of the monosaccharide.

96 sive disease caused by deficiency of alpha-N-acetylglucosaminidase, one of the enzymes required for t

97 gars on these moieties with mannosidase or N-acetylglucosaminidase, or the cleavage of the protein th

98 In the absence of the sleL-encoded N-acetylglucosaminidase, other cortex-lytic enzymes break

99 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (phosphodiester alpha-GlcNAcase) w

100 as a natural substrate for beta-(1 --> 4) N-acetylglucosaminidase producing a species possessing a s

101 Purified Jun a 1 was treated with beta-N-acetylglucosaminidase S and analysed using immunoblottin

102 ct inhibition of the peptide O-GlcNAc-beta-N-acetylglucosaminidase since neither the O-GlcNAc transfe

103 ase (NanA), beta-galactosidase (BgaA), and N-acetylglucosaminidase (StrH), have been previously demon

104 ear the amino or the carboxyl end of alpha-N-acetylglucosaminidase, suggesting a role for these regio

105 concluded that dspB encodes a soluble beta-N-acetylglucosaminidase that causes detachment and dispers

106 hereas the GH18 domain is an endo-beta-1,4-N-acetylglucosaminidase that exclusively processes the cen

107 at this gene encodes a broad-spectrum beta-N-acetylglucosaminidase that functions in glycan and chiti

108 SleL is an N-acetylglucosaminidase that plays the major role in hydro

109 olase family GH85 is a family of endo-beta-N-acetylglucosaminidases that is responsible for the hydro

110 stent with this observation, inhibition of N-acetylglucosaminidase, the enzyme involved in the remova

111 After N-glycan release by an endo-beta-N-acetylglucosaminidase, the mannosyl arms are trimmed by

112 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase ("uncovering enzyme" (UCE)).

113 GlcNAc-1-phosphodiester-N-acetylglucosaminidase ("uncovering enzyme" (UCE); EC 3.1

114 sferase) and GlcNAc-1-phosphodiester alpha-N-acetylglucosaminidase ("uncovering enzyme" or UCE).

115 estion by protein phosphatase 1 and beta-d-N-acetylglucosaminidase was more pronounced in STZ-diabeti

116 sphate receptor (M6PR)-dependent enzyme, B-N-acetylglucosaminidase, were also decreased in lysosomes

117 An exception to this is beta-N-acetylglucosaminidase, where 15% of the activity binds t

118 ne that the GH20 domain is an exo-beta-1,2-N-acetylglucosaminidase, whereas the GH18 domain is an end

119 eatment of the soluble complexes with beta-N-acetylglucosaminidase, which catalyzes hydrolysis of the

120 e structure is produced by an unusual beta-N-acetylglucosaminidase, which removes the terminal N-acet