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1 rine and phosphatidylglycerol being the most acidic.
2 g, that LN paracortical zones are profoundly acidic.
5 work, we identify two consensus active site acidic (a) and basic (b) motifs shared across the entire
6 ferred from the Lewis basic donor to a Lewis acidic acceptor to generate a reactive frustrated radica
13 se compounds represent the first potent, non-acidic, allosteric P2X1 receptor antagonists reported to
14 ched in the brain included those involved in acidic amino acid metabolism, Golgi apparatus, and ion a
15 we also define the fundamental nature of the acidic amino acid residues to the K-PPn target domain.
16 starting with the initiator Met followed by acidic amino acids and contributed 20% of the acetylatio
20 the zeolite frame were performed under both acidic and basic conditions to desilicate and dealuminat
21 ion of free and bound phenols from millet in acidic and basic hydrolytic conditions were compared for
22 Surface Methodology was then applied to both acidic and basic hydrolytic extractive conditions: the a
23 dies and mutation experiments show that both acidic and basic residues can catalyze the reaction.
24 ngly influencing the partitioning of gaseous acidic and basic species to aerosols, surface films, and
25 last ciders were also more floral, buttery, acidic and bitter than those made from mono- and multi-v
27 tudies, we show that phosphosites within the acidic and disordered N-terminus of Set2p affect H3K36 m
28 olecules, the most potent of which mimic the acidic and ionizable structure of the enzyme's natural s
31 ysis improved solubility of faba proteins at acidic and neutral pH, and their antioxidant properties.
32 ssue growth factor [CTGF], secreted protein, acidic and rich in cysteine), crosslinking genes/enzymes
33 itrogen-hydrogen bond strength of a Bronsted acidic anilinium tethered to one of the cyclopentadienyl
34 the N,N-di(4-bromophenyl)nitrenium ion under acidic aqueous conditions was examined via laser flash p
36 nding the interfacial molecular structure of acidic aqueous solutions is important in the context of,
43 m ion salts lead to enhanced acidities, more acidic catalysts than trifluoroacetic acid, and a linear
44 zers that operate with an alkaline anode and acidic cathode at 500 mA.cm(-2) with a total electrolysi
46 often overlooked due to its oxophilic, Lewis acidic character, which renders complexes of titanium le
47 her coagulation factors, suggesting that the acidic cluster serves a protective role against unwanted
49 op of SERINC5 and which is reminiscent of an acidic-cluster membrane trafficking signal, increases th
51 on suppressed the expression of transforming acidic coiled-coil protein-3 (TACC3), which stabilizes E
53 show that Sanpodo localization decreases at acidic compartments, associated with increased internali
56 database of 722 slightly polar phenolic and acidic compounds, including many of relevance to firefig
58 ion was degraded up to 99% within 96 h under acidic conditions (pH <= 5.5) in the presence of oxygen.
59 s pH dependent, with binding occurring under acidic conditions in the Golgi and release under conditi
61 oteolytic digestion of target proteins under acidic conditions to localize perturbations in exchange
62 ely substituted with vinylphosphonites under acidic conditions to yield the desired vinylphosphonothi
65 as Br(2)(g) in less than 10 min under weakly acidic conditions without significant formation of Cl(2)
75 3(2-) prevents its use at neutral pH due to acidic demetalation, highlighting the importance of the
79 Significantly, KSHV LANA mutants lacking the acidic domain reader sequence are deficient for establis
81 iates selective protein interactions between acidic domain readers and unacetylated, lysine-rich regi
83 contains two tandem, partially overlapping, acidic domain sequences homologous to the SET oncoprotei
84 ted outstanding oxygen-reduction activity in acidic electrolytes, which was further studied in proton
85 s unique characteristics compared to aqueous acidic electrolytes: 1) higher (de)protonation potential
88 domain is cleaved by cellular cathepsins in acidic endosomes, removing the glycan cap and exposing a
92 stability of the organozinc compounds in an acidic environment was exploited to accomplish the synth
93 of Sulfolobus islandicus is a response to an acidic environment, as at even higher temperatures in a
96 al fragility under the high temperatures and acidic environments of therapeutic applications signific
97 fluorometrically due to carbonate removal in acidic environments that directly affects the nanopartic
100 it is possible to stabilize citral in strong acidic environs having a pH as low as 1.0 using mixed su
103 irreversibly dissociates to fluoresce in the acidic extracellular tumor microenvironment due to the m
104 the nuclear pore complex (NPC) by binding an acidic face of the kinetochore checkpoint protein, MAD1,
106 mimics reactive fracture flow by passing an acidic fluid over a surface of mineralogically heterogen
108 H-dependent cytotoxicity of individual IOCs, acidic fractions, and reconstituted extracts of OSPW was
109 s of soil dissolved organic matter (DOM) and acidic functions carried out by its individual constitue
110 >= 1.0 pCi/L occurred most frequently where acidic groundwaters inhibited (210)Pb readsorption (fels
112 Nanoarchaeota, a symbiotic archaean found in acidic hot springs of Yellowstone National Park, USA.
113 sterolic fraction, after saponification and acidic hydrolysis of the samples, are extracted by solve
115 ed substantial rates of sulfate reduction in acidic hyperthermal terrestrial springs of the Kamchatka
117 of the hormone amyloid the pH increases from acidic in the secretory granule to neutral level in the
118 und that siRNA accumulation and stability in acidic intracellular compartments is critical for long-t
122 e compatible with spreading basalt powder on acidic loamy soils common across millions of hectares of
123 cellular bacterium that replicates within an acidic lysosome-like parasitophorous vacuole (PV) in hum
125 ime and temperature and concentration of the acidic mean, gave the best results, allowing definition
127 n (HER) is more sluggish in alkaline than in acidic media because of the additional energy required f
128 cleophilic addition of solvent to benzene in acidic media leading to substituted bicyclo[3.1.0]hex-2-
134 ore, a method involving sequential basic and acidic methanol extractions was developed and evaluated
137 amic assembly system that achieves lysosomal acidic microenvironment specifically inducing topologica
143 ts are formed not only during the heating of acidic, neutral and alkaline stevioside standard solutio
144 overpotentials of only 20, 50, and 36 mV in acidic, neutral, and alkaline electrolytes, respectively
147 injury (subfailure stretch), treatment with acidic Normal Saline (NS), and P2X7R activation with 2'(
148 tronite samples previously exposed to either acidic or alkaline fluids (hereafter referred to as "tre
150 removal of the N-Boc protective group under acidic or neutral conditions at elevated temperature, fo
152 weak-base 4-aminoquinoline drugs out of this acidic organelle, thus preventing these drugs from bindi
155 s, endoplasmic reticulum (ER), mitochondria, acidic organelles, F-actin, keratin, and soluble fluores
158 cruitment to chromatin, the pervasiveness of acidic patch binding and whether other nucleosome bindin
160 hows that cGAS binds to a negatively charged acidic patch formed by histones H2A and H2B via its seco
161 e unmasked histone 4 tails interact with the acidic patch of neighboring nucleosomes to drive short-r
162 cGAS monomers bridge two NCPs by binding the acidic patch of the histone H2A-H2B dimer and nucleosoma
163 domain of the accessory DNMT3B3 binds to the acidic patch of the nucleosome core, which orients the b
164 cleosome interactions have suggested that an acidic patch on the nucleosome disk may be a common site
165 hile both SIRT6 molecules associate with the acidic patch on the nucleosome, we find that the intrins
166 n associated motif (ChAM) and the nucleosome acidic patch region, which in 53BP1-expressing cells is
167 es bilaterally engage the nucleosome H2A/H2B acidic patch regions through the SMARCB1 C-terminal alph
168 to their evolutionarily conserved nucleosome acidic patch, we identify the positively charged alpha1-
169 actions between Snf5 and the histones at the acidic patch, which could serve as an anchor during acti
172 petitive proline-rich proteins interact with acidic pectins and play distinct roles in legume root ce
173 pothesize that repetitive PRPs interact with acidic pectins to form block-copolymer gels that can pla
175 the switch-on luminescence response of 4 at acidic pH (0 < 5.0), allowed us to specifically stain ly
177 Nanoparticle cellular uptake was enhanced at acidic pH - a condition that was also associated with gr
178 inds the polar amino-terminal lumen, whereas acidic pH affects the carboxy-terminal conformation.
183 be pivotal for maintenance of intravesicular acidic pH as well as the maturation, fusion, and traffic
185 rmance in combination with a standard C18 at acidic pH can be increased further through the applicati
187 dicted to be electrostatically frustrated at acidic pH in both pre- and post-fusion conformations.
188 cteristic feature of these granules is their acidic pH inside the granule lumen, which is required to
191 (2+)-ions and/or the outer hydrogel layer to acidic pH or crown ether leads to the triggered separati
192 -) flux, and it remains uncertain whether an acidic pH produced by loss of cystic fibrosis transmembr
193 APOL1 inserts into planar lipid bilayers at acidic pH to form pH-gated nonselective cation channels
195 and is Fc-engineered to increase affinity at acidic pH to the neonatal Fc receptor, and to reduce eff
196 reduction experiments on Gold at neutral to acidic pH values to elucidate the long-standing controve
199 rgy transfer (smFRET)-imaging, we found that acidic pH, Ca2+, and NPC1 binding synergistically induce
200 enzyme displayed higher relative activity at acidic pH, greater thermostability, and better storage s
201 ating factors in the tumor microenvironment (acidic pH, reactive oxygen species, and glutathione).
202 stics of the tumor microenvironment, namely, acidic pH, redox reactants, and hypoxia, are exploited.
203 rovar Typhimurium (S. Typhimurium) in mildly acidic pH, which S. Typhimurium experiences inside macro
207 three plant-based food models: carbohydrates/acidic pH/sweet - beetroot puree, proteins/neutral pH/sw
209 igate the associations of alpha-Syn with the acidic phosphoinositides (PIPs), phosphatidylinositol 4,
213 of how BigDyn modulates ASIC1a, identify the acidic pocket as the binding site for BigDyn, and thus h
214 tions of the catalytic subunit Isw1 with the acidic pocket of nucleosomes and the accessory subunit I
219 basic hydrolytic extractive conditions: the acidic procedure, optimized in terms of extractive time
220 here to interact directly with CypD via its acidic proline-rich C-terminus region and binding at the
223 rrent study, we generated a glial fibrillary acidic protein (GFAP) promoter-driven aromatase knock-ou
224 this study, we generated a glial fibrillary acidic protein (GFAP) promoter-driven aromatase knock-ou
225 ofilament light (Nf-L), and glial fibrillary acidic protein (GFAP) with common sporadic Alzheimer dis
226 the blood concentrations of glial fibrillary acidic protein (GFAP, p = 0.0074) and myelin basic prote
227 EF1D interacted with RNP subunits polymerase acidic protein (PA), polymerase basic 1 (PB1), polymeras
234 glial biomarkers S-100B and glial fibrillary acidic protein in CSF, and in BBB permeability (CSF/seru
236 chemistry using astrocytic (glial fibrillary acidic protein) and microglial (ionized calcium-binding
237 he use of selected markers (glial fibrillary acidic protein, doublecortin, calretinin and calbindin).
238 on includes upregulation of glial fibrillary acidic protein, stronger gap junction-mediated SGC-SGC a
239 carrying an I38T mutation in the polymerase acidic protein-a mutation that confers reduced susceptib
240 mino acid transporter, with glial fibrillary acidic protein-positive astrocytes but not CD68-positive
241 ide WD catalysts that are efficient near the acidic proton-exchange layer with those efficient near t
242 ically differentiated alkyl groups, alkenes, acidic protons alpha to carbonyl groups, tertiary amides
243 sponse to light, generating different mobile acidic protons and thus high on/off photoswitchable prot
244 f the north-east India sites was in slightly acidic ranges (6.1 +/- 0.5) and mean soil conductivity v
249 roteins, and it has been suggested that this acidic residue be removed prior to digestion, thus sacri
251 8 UMI (UIM- and MIU-related UBD) hydrophilic acidic residues abolishes RNF168-mediated ubiquitination
254 of a conserved basic residue and presence of acidic residues in the vestibule regions, conserved only
255 demonstrate that the peculiar clustering of acidic residues increases the intrinsic disorder propens
258 just a measuring stick ensuring placement of acidic residues precisely at the catalytic centre but al
259 orm pHinder, we identified a triad of buried acidic residues shared by all three receptors, a feature
260 T was observed at disulfide bonds but not at acidic residues, increasing and then apparently reversin
263 ones can be stored as amyloid fibrils within acidic secretory granules before release into the blood
264 stored in a functional amyloid state within acidic secretory granules before they are released into
265 ably, a bioinformatics analysis of the amino acidic sequence of Whirlin from different species sugges
268 y derived from the actuation of Hf(IV) Lewis acidic sites and the Bronsted acidic surface of Hf(18) .
271 y, tunable pore size/shape, accessible Lewis acidic sites), they can also display unique structures a
272 but is severely stunted by low-nutrient and acidic soil, to investigate how nutrient limitation affe
273 ) solid solutions during electrocatalysis in acidic solution as the solution can etch away Sr atoms.
278 When formed vesicles are transferred to more acidic solutions, electrochemical proton gradients are s
280 es TORC1-activated Art1 to detect N-terminal acidic sorting motifs within the same AATs, which initia
283 required in the electrochemical cell and an acidic stream was produced that can be used to periodica
284 catalyze C-C bond formation from weakly C-H acidic substrates; however, they accomplish this at pH 7
285 ucuronosyltransferases (GLCATs), is the only acidic sugar in AGPs with the ability to bind calcium.
287 metal center via a covalently appended Lewis acidic support is viable for promoting selective alkyne
291 Transfer of bromothymol blue (BTB) from acidic to basic aqueous slugs was performed for demonstr
293 actions between the intrinsically disordered acidic tracts and the positively charged arginine-rich r
295 articularly evident when they encounter less acidic tumor regions, for instance, during invasion.
296 ndation species for much of the arctic moist acidic tundra, which is currently experiencing extreme e
297 ronounced in summer when particles were most acidic, whereas in winter the relative importance of WS-
299 ng the physicochemical characteristics of an acidic zeotype framework at the molecular level can prov
300 phosphate acts as a counterion for the Lewis acidic zinc ion, which provides the activation of the al