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1 iological conditions (high salts, serum, and acidic pH).
2 nitrosative reactions are not influenced by acidic pH.
3 ive-stain electron microscopy at neutral and acidic pH.
4 n improved the microstructure of the gels at acidic pH.
5 boxilic acids (C4-diC) transporter active at acidic pH.
6 with bound antibodies and in the presence of acidic pH.
7 retion, and redox metabolism, in response to acidic pH.
8 the composition of the phases at neutral and acidic pH.
9 sing by furin-like proteases and exposure to acidic pH.
10 s of poly(rA) were first proposed to form at acidic pH.
11 he latter PhoQ-activating signals but not to acidic pH.
12 mer of hairpins seen in gp26 crystallized at acidic pH.
13 spholipids such as phosphatidylserine and an acidic pH.
14 itial stages of glucagon fibril formation at acidic pH.
15 p promoted better growth at alkaline than at acidic pH.
16 shold required to inhibit the RIM pathway at acidic pH.
17 modified with rhodamine-lactam responsive to acidic pH.
18 rotein synthesis when cells were cultured at acidic pH.
19 /A is induced by interacting with NTNHA-A at acidic pH.
20 eled with (111)In by 20 min of heating at an acidic pH.
21 d by substantial FeS dissolution at slightly acidic pH.
22 en conformations coexist as discrete ones at acidic pH.
23 II secretion system (T3SS) is upregulated by acidic pH.
24 limitations, especially the necessity for an acidic pH.
25 its open and locally closed conformations at acidic pH.
26 Greater lipid oxidation occurred under an acidic pH.
27 onment of tryptophan was less hydrophilic at acidic pH.
28 RP3 receptor abolished IL-1beta secretion at acidic pH.
29 sole aerobic succinate transporter active at acidic pH.
30 embranes highlighting the requirement for an acidic pH.
31 most polyphenols, since they are unstable at acidic pH.
32 h higher at near neutral or basic pH than at acidic pH.
33 the decrease in the phosphatase activity at acidic pH.
34 rityl, and a high aqueous solubility even at acidic pH.
35 to counter reductive stress associated with acidic pH.
36 l pH, but it inserts into the membrane at an acidic pH.
37 ation with D1 and D2, Ca(2+), and Golgi-like acidic pH.
38 and retention in external solution at highly acidic pH.
39 ha-helix-rich fold at both physiological and acidic pH.
40 presence of manganese at neutral to slightly acidic pH.
41 as Aspergillus CAD is best adapted to a more acidic pH.
42 concentration in a way that is triggered by acidic pH.
43 ion after separation by reverse-phase C18 at acidic pH.
44 l and pathological processes associated with acidic pH.
45 the PLA2R NC3 fragment and was increased in acidic pH.
46 lysosomal subcellular compartments and their acidic pHs.
47 more predominant nucleophiles at neutral and acidic pHs.
48 ered and finely regulated at either basic or acidic pHs.
49 the switch-on luminescence response of 4 at acidic pH (0 < 5.0), allowed us to specifically stain ly
50 unique Dallol hot springs, which are highly acidic (pH ~ 0) and saline (saturation) with maximum tem
51 Cuniculiplasmataceae, recently isolated from acidic (pH 1-1.5) sites in Spain and UK that are 16S rRN
52 sets from a high-temperature (80 degrees C) acidic (pH 2) hot spring located in Yellowstone National
53 aining the Maurliden mine (Sweden) is highly acidic (pH 2.3) and rich in zinc ( approximately 460 mg
55 S) wetland sediments under varying redox and acidic (pH = 2.6-5.8) conditions using U L3-edge X-ray a
56 tensive sulfide mineralization and generated acidic (pH 3.2-4.5), iron-rich drainage waters (up to 1.
59 ermoproteus populations were found in mildly-acidic (pH 5-6) sulfur sediments, and Pyrobaculum popula
62 ion of alphaS and betaS at pH 7.3 and mildly acidic pH 5.8, and we demonstrate that pH serves as an o
63 of over 2000 m, the pool is characterized by acidic pH (5.3), high temperature (68 degrees C), salini
64 to iron-limited media, oxidative stress, and acidic pH (5.5) for 0.5 to 2 h had no effect on abcA exp
65 end corresponded to a transition from mildly acidic (pH 6-7) and oxic conditions to mildly alkaline (
66 an IC50 value that is 10-fold more potent at acidic pH 6.9 associated with ischemic tissue compared t
68 Nanoparticle cellular uptake was enhanced at acidic pH - a condition that was also associated with gr
70 ighter association of LDL with LDLR-R410S at acidic pH, a reduced LDL delivery to late endosomes/lyso
72 nucleoside transport at pH 7.4, hENT3 is an acidic pH-activated lysosomal transporter partially loca
74 inds the polar amino-terminal lumen, whereas acidic pH affects the carboxy-terminal conformation.
79 o, CD38-mediated NAADP synthesis requires an acidic pH and a nonphysiological concentration of nicoti
80 Gleevec phenotypes require an intracellular acidic pH and are independent of tyrosine kinase inhibit
81 's cytoplasmic domain hindered activation by acidic pH and attenuated virulence in mice, but did not
82 The goal of this study was to examine how acidic pH and available carbon sources interact to regul
83 ed-pink hues (330 degrees -13.2 degrees ) in acidic pH and blues (230 degrees -262 degrees ) in alkal
85 athogen, Salmonella Typhimurium, responds to acidic pH and CAMP through the PhoPQ two-component regul
86 abolic studies demonstrate that signals from acidic pH and carbon source are integrated to remodel pa
87 erum and plasma, and their responsiveness to acidic pH and cis-diols (such as mannitol, a safe FDA ap
88 Similar to a phagolysosome, the CCV has an acidic pH and contains lysosomal hydrolases obtained via
91 imurium is virulent in mice, indicating that acidic pH and divalent cation sensing by PhoQ are dispen
92 The addition of S(0), in combination with acidic pH and elevated temperature (60 degrees C), resul
93 ncluding under diverse conditions such as at acidic pH and elevated temperature, or in the presence o
94 bon sources, Mtb fully arrests its growth at acidic pH and establishes a state of non-replicating per
95 se of lycopene in simulated gastric fluid at acidic pH and faster release in simulated intestinal flu
96 ory system is required to slow Mtb growth at acidic pH and functions to maintain redox homeostasis.
97 fluorimetric assay, which demonstrated that acidic pH and high osmotic pressure suppress genome rele
101 3-bound fibrinogen/fibrin and plasminogen at acidic pH and increased plasmin-mediated fibrinolysis.
105 ine pair at this location destabilizes HA at acidic pH and mediates fusion at a higher pH, while a gl
110 eability across the inner membrane at weakly acidic pH and outer membrane at highly acidic pH are fou
111 ions tested, has a better solubility at mild acidic pH and preserves a significant thermal stability
112 LRP1 with high affinity at both neutral and acidic pH and proved to be a potent inhibitor of LRP1 fu
113 responsive gel depot that can respond to the acidic pH and reactive oxygen species (ROS) within the t
114 pH, while entrapment in periplasm at weakly acidic pH and retention in external solution at highly a
119 secretory pathway, whereas it is resolved at acidic pH and Zn(2+) concentrations resembling those pre
120 ity of Pep2 for TreS (K(d) 3.5 mum at mildly acidic pH) and crystal packing favoring the 4 + 4 comple
122 y high concentrations of lactate, a slightly acidic pH, and specific short-chain fatty acid profiles,
123 ith the addition of both chitosan, targeting acidic pH, and urokinase plasminogen activator (UPA), ta
127 be pivotal for maintenance of intravesicular acidic pH as well as the maturation, fusion, and traffic
128 ate that the catalase activity is reduced at acidic pH, as compared with the activity at pH 7.4.
129 e binding strength and frequency increase at acidic pH, as indicated by the greater cell-rolling flux
134 ngori failed to activate PhoP/PhoQ in mildly acidic pH because it lacks both the ssrB gene and the Ss
138 eous chi1 and chi2 torsional fluctuations at acidic pH, but only restricted chi1 fluctuations at high
139 rease ligand controlled dissolution rates at acidic pH, but the extent that this also occurs at circu
140 rgy transfer (smFRET)-imaging, we found that acidic pH, Ca2+, and NPC1 binding synergistically induce
141 rmance in combination with a standard C18 at acidic pH can be increased further through the applicati
142 s-the combination of lactate ion buildup and acidic pH-can increase the heterogeneity of FDG uptake i
147 bservations extend previous indications that acidic pH causes the M1 layer to dissociate, leaving the
148 sensitive (dUPS) polymers that amplify small acidic pH changes to efficacious therapeutic outputs.
149 ndergo a structural change when subjected to acidic pH comparable to that seen in endosomal compartme
156 howed its transport of riboflavin to have an acidic pH dependence, saturability (apparent Km = 1.4 +/
157 higher Vmax and Km values as well as higher acidic pH-dependent activity than NtRbcS-M, an isoform e
160 ld be attributed to enhanced activity of two acidic pH-dependent, ceramide-generating enzymes, beta-g
163 e sought to examine the mechanistic basis of acidic pH-driven hENT3 nucleoside transport with site-di
165 vely release its DOX payload triggered by an acidic pH environment (pH~5) and/or applying an 808nm NI
166 microparticles during a 10-hour period in an acidic pH environment and the complete degradation of on
168 Furthermore, BCM could be disassembled in an acidic pH environment or by administrating mannitol, fac
169 hysiological conditions, but is activated by acidic pH, enzymatic up-regulation, or hypoxia once they
170 overall icosahedral structure at this mildly acidic pH, except in the membrane-binding region, where
171 e variants with increased FcRn affinities at acidic pH exhibited extended serum half-lives relative t
172 ed the bacterial transcriptional response to acidic pH experienced during the shift from planktonic t
173 mib release was accelerated significantly by acidic pH, facilitating drug availability in the acidic
175 the association of APOL1 with the bilayer at acidic pH, followed by the opening of APOL1-induced cati
176 f simple secondary amines release are 0.5 at acidic pH from 3.9 to 6.6 dropping to 0.1 at neutral pH
177 enzyme displayed higher relative activity at acidic pH, greater thermostability, and better storage s
178 , traditionally assumed to be stable only at acidic pH, have been found to form under near-physiologi
180 are achieved at higher chlorine doses and at acidic pH; (ii) chlorination is mostly restricted to the
181 cellent stability toward neutral to slightly acidic pH in 10 mM sodium phosphate buffer, mitigating t
182 dicted to be electrostatically frustrated at acidic pH in both pre- and post-fusion conformations.
184 ular pH homeostasis and were not observed if acidic pH in intracellular compartments was neutralized.
186 lead to cystine accumulation and crystals at acidic pH in patients with nephropathic cystinosis, a ra
187 oP-dependent genes were minimally induced by acidic pH in the non-pathogenic species Salmonella bongo
188 the aggregation process of human insulin at acidic pH in the presence of sulfate ions using a combin
194 ortantly, inhibition of ASIC-3 prevented the acidic pH induced proinflammatory and pain-related pheno
195 Influenza virus entry is mediated by the acidic-pH-induced activation of hemagglutinin (HA) prote
197 sed the increased viscosity, suggesting that acidic pH influences mucin electrostatic interactions.
198 cteristic feature of these granules is their acidic pH inside the granule lumen, which is required to
204 e that long-term exposure of cancer cells to acidic pH leads to a metabolic reprogramming toward glut
206 alent cations and induced in environments of acidic pH, limited divalent cations, and cationic antimi
208 ates in, rendering the lumenal flow strongly acidic (pH </= 2) that suppresses eluite weak acid disso
211 lysosome function requires maintenance of an acidic pH maintained by proton pumps in combination with
212 th an acidification pretreatment and at more acidic pH, MBM biochar causes precipitation of a ZnPO4 p
213 ey were not particularly vulnerable to heat, acidic pH, nitrosative or oxidative stress, yet exhibite
215 Preexposure of isolated virions to mildly acidic pH of 5 to 6 partially inactivates HSV infectivit
218 olysosomal maturation pathway, resisting the acidic pH of lysosomes to form a parasitophorous vacuole
220 xploits the catastrophic disassembly, at the acidic pH of the tumour milieu, of pH-sensitive positron
222 H may become vitamin-limited or inhibited by acidic pH once injected into field sites, resulting in i
227 (2+)-ions and/or the outer hydrogel layer to acidic pH or crown ether leads to the triggered separati
228 gered by pathogenic microenvironments (e.g., acidic pH or low oxygen levels) for localized and contro
230 ly sensitive to pH: their induction required acidic pH (pH 5.3), but their magnitude could be increas
231 es in water, at either neutral or moderately acidic pH (phosphate buffer, pH 5) depending on the cata
232 FcRn with high affinity at both neutral and acidic pH, prevents the simultaneous binding of IgG, and
233 -) flux, and it remains uncertain whether an acidic pH produced by loss of cystic fibrosis transmembr
235 ating factors in the tumor microenvironment (acidic pH, reactive oxygen species, and glutathione).
236 stics of the tumor microenvironment, namely, acidic pH, redox reactants, and hypoxia, are exploited.
240 concentration were observed, whereas the OER acidic pH regime exhibited a quasi-infinite Tafel slope
242 ulation, glucagon fibrillizes rapidly at the acidic pH required for solubility and is therefore formu
245 re of P22 tail needle (gp26) crystallized at acidic pH reveals a slender fiber containing an N-termin
247 aired RhoA activation after an extracellular acidic pH shift in IBD patients, irrespective of the rs8
248 od samples and subjected to an extracellular acidic pH shift, cAMP accumulation and RhoA activation w
250 natants collected in sorption experiments at acidic pH showed that the approximately 5700 compounds i
251 aim here was to address the hypothesis that acidic pH, similar to that found in degenerate IVDs, lea
252 ngages and suppresses T cells selectively at acidic pH such as that found in tumour microenvironments
253 th Fe(3+) and Cu(2+) and retains activity at acidic pH, suggesting it may also function within intrac
254 imerization domains that were most active at acidic pH, suggesting that these domains have a role in
255 three plant-based food models: carbohydrates/acidic pH/sweet - beetroot puree, proteins/neutral pH/sw
256 he formulation exhibited greater toxicity at acidic pH than at physiological pH, using the human pros
257 1alpha and IL-1beta at pH 7.4 and pH 6.2, an acidic pH that can be reached under inflammatory or isch
258 anges produced in the PhoQ PD on exposure to acidic pH that indicate structural flexibility is induce
259 orting that Mtb has restricted metabolism at acidic pH that results in the slowing of bacterial growt
260 el Fc variants with high affinity binding at acidic pH that vary in pH 7.4 affinities and assessed ph
261 hemical reduction of CO, finding that (1) at acidic pH, the C1 pathway proceeds through COH to CHOH t
262 omains packed in a firm assembly, whereas at acidic pH, the three IgG-binding domains form an elongat
264 channel is closed at neutral pH and opens at acidic pH to allow the rapid access of urea to cytoplasm
265 APOL1 inserts into planar lipid bilayers at acidic pH to form pH-gated nonselective cation channels
267 and is Fc-engineered to increase affinity at acidic pH to the neonatal Fc receptor, and to reduce eff
269 gh these proteins could bind ligands even at acidic pH unlike wild-type ApolPBP1, they had ~4-fold re
270 binding to VEGF was dramatically reduced at acidic pH values (pH 5.0-6.5), whereas VEGF binding to F
271 idis at basic pH values (pH = 9) compared to acidic pH values (pH = 6) due to a smaller size and posi
275 that CrCAH3 was most active at the slightly acidic pH values prevalent in the thylakoid lumen under
277 gates have higher activities at the slightly acidic pH values that separate normal and cancerous tiss
278 reduction experiments on Gold at neutral to acidic pH values to elucidate the long-standing controve
279 Na(+) dependence was observed at neutral and acidic pH values, indicating the exclusive use of Na(+)
281 lux through hTRPA1 occurred at physiological acidic pH values, were concentration-dependent, and were
285 stingly, the reduced Avastin-VEGF binding at acidic pH was rescued by heparin, as was Avastin's abili
286 neutral pH (but not membrane association at acidic pH) was prevented by the interaction of APOL1 wit
287 Female NOD mice that were maintained on acidic pH water (AW) developed insulitis and hyperglycem
289 cate limited stability of trans-5-OH-TBOH at acidic pH where it undergoes concurrent, carbocation-med
291 in neuroendocrine cells are maintained at an acidic pH, which is part of the electrochemical driving
292 revealed cis-12-OH-TBOH to be more stable at acidic pH, which is the only condition where its reversi
293 rovar Typhimurium (S. Typhimurium) in mildly acidic pH, which S. Typhimurium experiences inside macro
294 f the paclitaxel payload within six hours in acidic pH, which was accompanied by switching of fluores
295 ligand at physiological pH and release it at acidic pH while undergoing a conformational change.
296 acts with E at neutral pH but is released at acidic pH, while the pr region interacts with E at acidi
297 of a hydroxyl group enhanced the binding at acidic pH, whilst this substitution reduced the strength
298 tion and elongation are strongly enhanced at acidic pH, with a maximum close to the pI of actin.
299 t oxidants of Fe(II) in aqueous solutions at acidic pH, with rate constants substantially larger than
300 with 2-mercaptoethanesulfonic acid at mildly acidic pH yielded alpha-thioesters that were directly us