ライフサイエンスコーパス: acidify

1 phosphates via sample digestion (heating and acidifying).

2 sitol-3-kinase from these organelles as they acidify.

3 rm activity, whereas neurons are observed to acidify.

4 lifespan, but that daughter cell vacuoles re-acidify.

5 deficient NC cells remain immature but still acidify.

6 promoted by the failure of M1 phagosomes to acidify.

7 , failure to acquire LAMP-1 and inability to acidify.

8 ely open, the cytosol of sour taste cells is acidified.

9 (-1) dissolved iron and became progressively acidified.

10 ant LAMP1-positive vacuoles that were poorly acidified.

11 ocean impacts narrow as the ocean warms and acidifies.

12 ctrospray ionization (ESI) of ubiquitin from acidified (0.1%) aqueous solution produces abundant ubiq

13 fast UHPLC separation (5min separation using acidified 10% MeOH isocratic flow in a CORTECS C18 colum

14 long and 5 mm diameter) and then eluted with acidified 5 M NaCl solution directly into a sodium aceta

15 The acidified 70% acetone was identified as the ideal solven

16 sted samples and haem Fe was extracted using acidified 80% acetone for 60 min.

17 deling, we determined that by stochastically acidifying a phagolysosome to a pH within the observed d

18 V-ATPase) activity, accounts for the reduced acidifying ability of peripheral lysosomes.

19 Extraction was performed with acidified acetonitrile (acetic acid 1% (v/v)), and addit

20 includes a prior protein precipitation with acidified acetonitrile for all samples and an additional

21 Extraction was performed with acidified acetonitrile, followed by a cleanup step with

22 that luminal ATP and adenosine modulate the acidifying activity of CCs via the purinergic ADORA2B an

23 luminal ATP and adenosine to modulate their acidifying activity via the adenosine receptor ADORA2B a

24 in pfk2Delta, and the vacuolar lumen was not acidified after reassembly.

25 prepared using two dilutions of verjuice as acidifying agent and compared with the traditional vineg

26 The different acidifying agents resulted in pickled cucumbers giving d

27 rsely, expressing ATP12A in CF mouse airways acidified airway surface liquid, impaired defenses, and

28 H(+)/K(+) adenosine triphosphatase (ATP12A) acidified airway surface liquid, which impaired airway h

29 M2 ion channel causes the virion interior to acidify also.

30 In a previous study, we showed that acidified amebic lysosomes are required for both amebic

31 This effect is demonstrated by exposing acidified ammonium sulfate particles to 250 parts per bi

32 When pre-concentrated micelles were acidified, an earlier gelation point was shown, as well

33 tion domain) as the lumen of the endosome is acidified and 2) low pH, in conjunction with acidic lipi

34 rt-term N and P enrichment experiment in non-acidified and acidified soil in a semiarid grassland on

35 d by combined N and P enrichment in both non-acidified and acidified soil.

36 Milk samples were initially acidified and centrifuged, and then the supernatant was

37 Some endocytic vesicles were acidified and colocalized with LysoTracker.

38 with phagocytosis because phagosomes become acidified and the average fluorescence lifetime of EGFP

39 The milks were subsequently acidified and the distribution of protein between colloi

40 limate change as oceans continue to warm and acidify and thermal anomalies grow in frequency and inte

41 whole blood was added to the sample chamber, acidified, and the HCN gas evolved was actively transfer

42 ria-containing vacuoles quickly (</= 15 min) acidify, and that this was coincident with greater virul

43 Compared to Raw-, Unstarted- and Chemically Acidified-AP, Fermented-AP promoted the highest levels o

44 The method involved mixing sample with acidified aqueous acetonitrile, followed by salt-out liq

45 ions is produced by nanoESI from a slightly acidified aqueous solution with the micron outer diamete

46 Acidified aqueous solutions containing unfolded proteins

47 e intramitochondrial pH of astrocytes, which acidifies as a consequence of glutamate uptake, with the

48 orter of acidified mitochondria reveals that acidified axonal mitochondria originating from the retin

49 at addition of moderate amounts of pepsin to acidified bovine insulin at close to physiological tempe

50 Moreover, the injection of CO(2)-acidified brine at high rates resulted in a more permeab

51 Solution chemistry indicated that CO(2)-acidified brine preferentially dissolved dolomite until

52 nt with an experimental study in which a CO2-acidified brine was injected into a fracture in the Dupe

53 omography before and after exposure to CO(2)-acidified brine, allowing mineral phase and voidspace di

54 We studied two CO2-acidified brines having the same pH (3.3) and comparable

55 ed intradermally to nape or cheek skin, (ii) acidified buffer elevated intracellular calcium levels i

56 ant and microbial community structure in non-acidified but not in acidified soil, and had no effect o

57 tion of a mixed suspension of native and pre-acidified casein micelles was observed using rheology.

58 milieu into an endosome, whose contents then acidify, causing changes in the viral matrix protein (M1

59 An acidified citrate cysteine medium (ACCM-2) has been deve

60 ression of all IFITMs expanded vesicular and acidified compartments within cells, there were marked p

61 on the exudation of reducing, ligating, and acidifying compounds.

62 ascidians and 29% sponges after 100 days in acidified conditions (pH 7.7).

63 Long-term exposure to acidified conditions predicted for the year 2100 and bey

64 ariability found among samples maintained in acidified conditions relative to controls, suggests a po

65 communities maintained in or transplanted to acidified conditions, and altered community structure in

66 Under acidified conditions, Lgmn cleaved within the extracellu

67 cyanobacterium Trichodesmium decreased under acidified conditions, notwithstanding a beneficial effec

68 berrant shapes being observed only under the acidified conditions.

69 current and predicted stability under ocean acidifying conditions.

70 sive increase in oxidative ATP supply during acidifying contractions.

71 te in sodium chloride brines and compared to acidified cucumbers.

72 -5 fold in fermented cucumbers compared with acidified cucumbers.

73 dissolution of calcite particles by flow of acidified desalinated water through a bed packed with mi

74 y flow of micron-size calcite particles with acidified desalinated water.

75 In acidified dough the pattern of volatile metabolites allo

76 were investigated and compared to chemically acidified dough.

77 roalgae enriched breads made with chemically acidified doughs or sourdoughs had higher Total Phenolic

78 esence of either 10% sourdough or chemically acidified doughs.

79 When mice received acidified drinking water (pH 2.5-2.9) instead of normal

80 Interestingly, in control mice, acidified drinking water caused brain region-specific gl

81 The dogma that the synaptic cleft acidifies during neurotransmission is based on the corel

82 water Al concentrations continue to threaten acidified ecosystems across the northern hemisphere.

83 elevated summer temperatures in historically acidified ecosystems.

84 ngly enhanced AN-PEP activity because of its acidifying effect.

85 ecovery from acidification, due to decreased acidifying emissions and deposition, has led to an incre

86 Activating TRPML1 channels with ML-SA1 acidified endolysosomes and restricted Tat-mediated HIV-

87 ulation, cytosolic NADP(+) is transported to acidified endolysosomes via connexin 43 (Cx43) and gated

88 These results suggest that acidifying endolysosomes by activating TRPML1 or BK chan

89 e to activate HIV-1 LTR, we hypothesize that acidifying endolysosomes may enhance Tat degradation in

90 V-ATPase activity are avirulent and fail to acidify endomembrane compartments, exhibiting pleiotropi

91 esting RGS4 traffics through PM recycling or acidified endosome pathways.

92 transfer of Wg to DFz2 within the merged and acidified endosome to initiate Wg signaling.

93 of cellular entry requires trafficking to an acidified endosome, which promotes translocation across

94 polymeric nanoparticle for the targeting of acidified endosomes to precisely inhibit endosomal signa

95 R) redistributes from the plasma membrane to acidified endosomes, where it signals to maintain pain.

96 gests hosts may need to adapt not only to an acidified environment, but also to changes in their Symb

97 e also display enhanced expression of the SC acidifying enzyme, secretory phospholipase A2f (sPLA2f).

98 ouring cells, might be translatable to other acidifying epithelia.

99 The blueberries were soaked in acidified ethanol, filtered, and the filtrate was cleane

100 one concentration (%), time of extraction in acidified ethanolic solution (min) and ethanol concentra

101 e of HP (HP-G) in human urine after a simple acidified ether extraction procedure when using multiseg

102 luded cryogenic comminution, extraction with acidified ethyl acetate or acetonitrile, and dilution of

103 Samples were extracted with acidified ethyl acetate, MgSO4 and CH3COONa and cleaned

104 ecifically target the plasma membrane in the acidified extracellular medium that bathes cells in tumo

105 Interactions between acidified fluid and minerals with different reactivities

106 eactions in fractured basalts exposed to CO2-acidified fluids.

107 g acid stress, bacteria internal pH promptly acidifies, followed by recovery.

108 E. ictaluri-containing vacuoles (ECV) became acidified following ingestion by head kidney-derived mac

109 This compartment must be acidified for Salmonella to survive within macrophages,

110 Decades of acid rain have acidified forest soils and freshwaters throughout montan

111 eystone organism in a more nutrient-limited, acidified future ocean.

112 Specimens were demineralized using acidified gel (pH = 4.5) for 5 wk and scanned every week

113 nant protein and electron cryo-microscopy of acidified hantavirus allows us to propose a model for en

114 For such measurements, acidified ice-core meltwater typically is analyzed conti

115 By contrast, M2 phagosomes proceed to acidify immediately in order to clear apoptotic bodies r

116 ) emissions are sufficient to neutralize the acidifying impacts of human CO(2) emissions.

117 mers that undergo conformational change when acidified in the endosome.

118 reasoned that the Salmonella cytoplasm might acidify in the macrophage vacuole to activate OmpR-depen

119 either genetic or pharmaceutical approaches acidified intracellular pH and reduced cell growth.

120 vesicular adenosine triphosphatase (ATPase) acidifies intracellular compartments, including synaptic

121 ase (V-ATPase) is a rotary motor enzyme that acidifies intracellular organelles and the extracellular

122 Vacuolar H(+)-ATPases (V-ATPases) acidify intracellular organelles and help to regulate ov

123 ar membrane, secreting acids to the lumen or acidifying intracellular compartments.

124 of GlcNAc raises the ambient pH rather than acidifying it, as occurs after dextrose catabolism.

125 ication of the host cell vacuole, Salmonella acidifies its own cytoplasm in response to the low extra

126 Polyacetylenes were retained better in acidified juices and cold storage temperatures (4 degree

127 -524) is sufficient to pilot the effector to acidified LAMP1-positive lysosomal compartments, where W

128 Despite localization to acidified late phagosomes, viable G. bethesdensis cells

129 raction of REEs from residues often generate acidified leachates that require highly selective separa

130 ) cortical neurons, the GA is severely under-acidified, leading to osmotic swelling.

131 could account for enhanced function, because acidifying lightly pigmented human SC resets barrier fun

132 utophagosomes transfer cytosolic material to acidified lysosomes for degradation following soluble N-

133 ed direct and precise rhbeta-gal delivery to acidified lysosomes.

134 ed direct and precise rhBeta-Gal delivery to acidified lysosomes.

135 compartment defects in resistance; V-ATPase acidifies lysosomes and related organelles, whereas adap

136 r H(+)-ATPase (V-ATPase), a proton pump that acidifies lysosomes.

137 GA core and released specifically within the acidifying macrophage phagosomes.

138 ance in response to acidic stress and inside acidified macrophages.

139 ltaBbPacC mutant showed a reduced ability to acidify media during growth due to failure to produce ox

140 mutants showed a reduced ability to grow in acidified medium.

141 The epsilon in acidified MeOH and buffer pH 1 ranged between ~16,000-30

142 hilized fruit samples were extracted with an acidified MeOH mixture assisted by ultrasound.

143 and to evaluate their spectral behaviors in acidified methanol (MeOH) and buffers pH 1-9.

144 Major anthocyanins were extracted with acidified methanol and characterised in powdered berry e

145 Compared with methanol solvent, using acidified methanol led to increased extraction yield by

146 reparation included analytes extraction with acidified methanol, concentration by evaporation and fil

147 (HPLC-DAD) was applied after extraction with acidified methanol, to determine 12 bioactive phenolic c

148 om minced muscle samples involved the use of acidified methanol, ultrasound treatment and centrifugat

149 An acidified methanol-water mixture was used as an effectiv

150 The method is based on extraction with an acidified methanol-water mixture.

151 s commonly used for phenols, extraction with acidified methanol-water was chosen as the best to quant

152 When skim milk containing pre-acidified micelles was re-equilibrated to the original p

153 Pre-acidified micelles were prepared by addition of glucono-

154 PR4, GPR65, and GPR68) regulate signaling in acidified microenvironments by sensing protons (H(+)).

155 y with its potent inhibitor HOE 642 not only acidified microglia, abolished the BK-triggered dynamic

156 Sample preparation improvements included acidified, microwave-accelerated, PNGase F N-glycan rele

157 ealthy men who had consumed a single dose of acidified milk (800 g) which contained 38.8 g lactose.

158 ubjects were randomly assigned to receive an acidified milk drink containing >/=10(9) colony-forming

159 duced tandem fluorophore protein reporter of acidified mitochondria reveals that acidified axonal mit

160 ere, we show that the cytosol of yeast cells acidifies modestly in early aging and sharply after sene

161 The acidified mucilage was used as an extracting medium for

162 ncentrations increase considerably in gypsum-acidified must, although they fell markedly after fermen

163 The photoactivatable, acidifying nanoparticles (paNPs) demonstrate lysosomal u

164 cales and that as coastal oceans continue to acidify, negative effects on these populations may becom

165 trate that the combination (termed AB569) of acidified nitrite (A-NO(2) (-)) and Na(2)-EDTA (disodium

166 and a treatment arm that received 3 doses of acidified nitrite applied topically for 12 weeks with an

167 daptive capacity of species to respond to an acidified ocean, and, as a result, predictions regarding

168 change is expected to warm, deoxygenate, and acidify ocean waters.

169 ed to parental care are more protected in an acidifying ocean compared to their relatives employing b

170 coral health and resilience in a warming and acidifying ocean.

171 seas, intensifying storms and droughts, and acidifying oceans.

172 ke the traditional sterilized product, these acidified olives only needed pasteurization to assure it

173 ke of anthropogenic carbon dioxide (CO2) has acidified open-ocean surface waters by 0.1 pH units sinc

174 ted by N or P enrichment alone in either non-acidified or acidified soil, but was increased by combin

175 ffect on nematode community structure in non-acidified or acidified soil.

176 t affect most soil nematode variables in non-acidified or acidified soil.

177 Two extraction procedures using either hot acidified or temperate water at its genuine pH were comp

178 ectrical current through the system tends to acidify (or basify) the anolyte (or catholyte), their ef

179 n due to higher N availability, as soils are acidified, or as micronutrients become increasingly limi

180 tions, engulfed mitochondria remained in non-acidified organelles for hours to days, illustrating eff

181 Lysosomes are ubiquitous acidified organelles that degrade intracellular and extr

182 s are conserved ATP-driven proton pumps that acidify organelles.

183 Thus, in the acidified OSCC microenvironment, Lgmn activates PAR(2) b

184 inetics in Cd-Zn cocontaminated alkaline and acidified paddy soils, under various flooding periods an

185 intracellular pathogen that replicates in an acidified parasitophorous vacuole derived from host lyso

186 iplasmic protease MarP for Mtb to survive in acidified phagosomes and establish and maintain infectio

187 esistance, and intracellular survival within acidified phagosomes.

188 When compared with the control (pHi 7.3), acidifying pHi to 6.3 or alkalinizing pHi to 8.3 and 8.8

189 phodepleted mice, implicating T-cells in the acidifying process.

190 base-poor, parent materials is sensitive to acidifying processes on millennial timescales.

191 SA300 clone, the USA300-containing phagosome acidified rapidly and acquired the late endosome and lys

192 rich in isothiocyanates it is recommended to acidify raw cabbage salads and prepare shortly boiled bl

193 Here we show that NHE5 potently acidifies recycling endosomes in PC12 cells.

194 ires osteoclasts to generate and maintain an acidified resorption compartment between the apical memb

195 ve flow-through CO2 equilibration between an acidified sample and an indicator solution with a fast r

196 ve flow-through CO2 equilibration between an acidified sample and an indicator solution with a respon

197 ydrides were generated in the reaction of an acidified sample with NaBH4 after pre-reduction with KI-

198 reviewed experimental data on the effects of acidified seawater on calcifying species growth, reprodu

199 opment, allowing serpulids to do best at the acidified site by the end of the experiment, although ea

200 We show that succession at the acidified site was initially delayed (less community cha

201 Nitrite addition to the acidified sludge at a concentration of 20 mg NO2(-)-N/L

202 the biomass of most microbial groups in non-acidified soil (the decrease tended to be greatest with

203 P enrichment experiment in non-acidified and acidified soil in a semiarid grassland on the Mongolian

204 with combined N and P enrichment) but not in acidified soil, and did not affect most soil nematode va

205 munity structure in non-acidified but not in acidified soil, and had no effect on nematode community

206 enrichment alone in either non-acidified or acidified soil, but was increased by combined N and P en

207 tode community structure in non-acidified or acidified soil.

208 soil nematode variables in non-acidified or acidified soil.

209 N and P enrichment in both non-acidified and acidified soil.

210 othesis that calcium limits forest growth in acidified soils.

211 en shown to decrease species richness and to acidify soils, each of which may diminish the long-term

212 77-83% moisture content) were conditioned in acidified solution at 5, 15 and 25 degrees C, absence of

213 t of carbonate mineral reactivity with CO(2)-acidified solution is voidspace generation through physi

214 corns, and emphasise the importance of using acidified solutions for the extraction of corn-based ant

215 hm as small as 3.7% achieved in desalted and acidified solutions.

216 n conditions and efficiencies using a single acidified solvent have been assessed.

217 nvironmental problem, but efforts to restore acidified streams and biota have had limited success.

218 The secondary production of culturally acidified streams is low, with a few species of generali

219 ATPase) is an ATP-dependent proton pump that acidifies subcellular compartments in all eukaryotic org

220 TPase) is a multisubunit enzyme complex that acidifies subcellular organelles and the extracellular s

221 ta vacuoles were alkalinized and the cytosol acidified, suggestive of impaired V-ATPase proton transp

222 ations were only enhanced in the presence of acidified sulfate aerosol, consistent with prior work.

223 ich form during the BVOC oxidation, into the acidified sulfate particles is shown to explain the latt

224 facility in the presence of nonacidified and acidified sulfate seed aerosol.

225 otons (coreleased with neurotransmitter from acidified synaptic vesicles).

226 CS exposure acidified the airspaces and induced localization of the

227 Inhibition of extramitochondrial CA activity acidified the matrix (as determined by fluorescence meas

228 Illumination with amber light acidified the surrounding interstitium and led to activa

229 They acidified the yeast cytosol and caused pH-sensitive grow

230 erm and carries a proton inward current that acidifies the cytosol.

231 The gastric proton pump H(+),K(+)-ATPase acidifies the gastric lumen, and thus its inhibitors, in

232 d the vacuolar H(+)-ATPase (V-ATPase), which acidifies the lysosome-like vacuole.

233 expresses vacuolar H(+)-ATPase (VHA), which acidifies the symbiosome space down to pH approximately

234 tetrameric transmembrane proton channel that acidifies the virion after endocytosis.

235 ctivating process in which proton permeation acidifies the virion to release the viral RNA and core p

236 sed, whereby auxin promotes proton efflux to acidify the apoplast and facilitate the uptake of solute

237 The ability of the mutant strain to acidify the defined medium during growth in the presence

238 tional sclerotia and have reduced ability to acidify the environment.

239 (V-ATPases) are essential proton pumps that acidify the lumen of subcellular organelles in all eukar

240 anthropogenic carbon dioxide (CO2) emissions acidify the oceans, calcifiers generally are expected to

241 ructure supplying the retina act together to acidify the red blood cell leading to O(2) secretion.

242 The sample preparation steps acidify the sample, decompose organics, and convert all

243 apses show that neurotransmission itself can acidify the synaptic cleft, likely due to the corelease

244 rotein lipocalin 2 (LCN2) and protons, which acidify the urine.

245 4, distinct genes, such as PH1 and PH5, that acidify the vacuole.

246 hemical library to search for compounds that acidify the yeast cytosol in vivo using pHluorin-based f

247 effect of acidic medium could be mimicked by acidifying the cytosol with bafilomycin A1, a proton pum

248 cent muscle cells to contract by transiently acidifying the extracellular space between the intestine

249 id and protons to maintain intracellular pH, acidifying the extracellular space.

250 ng in the activation of the O2' nucleophile, acidifying the general acid C75, and stabilizing the non

251 Acidifying the host tissue enhanced virulence of the oxa

252 , Escherichia coli, and Proteus mirabilis by acidifying the proximal colon and triggering short chain

253 Most plant species acquire Fe by acidifying the rhizosphere and reducing ferric to ferrou

254 HA is essential for frustule biosynthesis by acidifying the SDVs and regulating the insertion of othe

255 bound uropathogenic E. coli and responded by acidifying the urine and secreting the bacteriostatic pr

256 rich cells (MRCs) and have a crucial role in acidifying the urine via apical V-ATPase pumps.

257 east cells grown in abundant glucose tend to acidify their extracellular environment, they raise the

258 They acidify their microenvironment hence membrane voltage is

259 and 52.4% of p.E161K carriers were unable to acidify their urine below pH 5.3 and thus, can be consid

260 Sample water is first acidified to convert all DIC to carbon dioxide (CO2).

261 total dissolved iron analysis, samples were acidified to pH 2.0 in the presence of 30 muM DHN and le

262 intained around -120 mV, and the apoplast is acidified to pH 3.

263 hemical properties of 5% w/v SMP dispersions acidified to pH 3.0 using chelating gluconic acid (GA) a

264 Its cytoplasm acidifies to pH 5.6; acidification activates pathogenici

265 A combination of effects acidifies tumor cell interiors, and cells pump out lacti

266 ed that without amelogenins the enamel would acidify unless ameloblasts were buffered by alternative

267 mobilization of metal contaminants by brine acidified upon contact with CO2 during geologic carbon s

268 ns remain regarding how bacteria survive the acidified vacuole and how acidification affects bacteria

269 of macrophages, where Brucella resides in an acidified vacuole at a pH of 4-4.5 during the early phas

270 ts growth medium in vitro, and resided in an acidified vacuole within macrophages.

271 virulence mechanisms differentially rely on acidified vacuoles and that the loss of both vacuolar (V

272 c machinery to discriminate fully loaded and acidified vesicles from vesicles undergoing neurotransmi

273 et cells triggers toxin internalization into acidified vesicles, whereupon cryptic segments from with

274 Here we investigated if acidified water administered from postnatal day 21 has t

275 A gradient method was developed using acidified water and acetonitrile combined with high colu

276 Extractions with acidified water and ultrasound were not effective to rec

277 dicted to form in situ from pyridine (Py) in acidified water at a cathode surface and to be the key t

278 The crude pigment extract obtained with hot acidified water contained low concentrations of C6 aldeh

279 as markedly different from control mice, and acidified water differentially changed the gut microbiot

280 These results indicate that acidified water may provide therapeutic benefit to CLN3

281 ects of the extraction methods and solvents (acidified water pH 2.0, ethanol+water 50% v/v and ethano

282 rile, and dilution of the final extract with acidified water prior to LC-MS/MS analysis.

283 Indeed, acidified water temporarily attenuated the motor deficit

284 terials and with a diffusion-limited rate in acidified water, is efficient as well as oxygen tolerant

285 5) degradation over 2 weeks when prepared in acidified water.

286 ls, indicating a disease-modifying effect of acidified water.

287 sistent spatial mosaic in the penetration of acidified waters into ecologically-important nearshore h

288 electrochemical pulse, so as to controllably acidify well-confined thin layer samples.

289 The cytoplasm is acidified when V-ATPase is inhibited; thus we conducted

290 se the oceanic surface water to continuously acidify, which has multiple and profound impacts on coas

291 extraction with primary secondary amine and acidified with 0.1% formic acid.

292 modified QuEChERS technique in acetonitrile acidified with acetic acid (1%, v/v) and citrate-buffere

293 In oils, a single extraction using water acidified with formic acid (1%) was performed, while in

294 extraction was performed using acetonitrile acidified with formic acid (1%, v/v).

295 on of deprotonated carboxylates, a sample is acidified with HCl, and the quantity of H(+) absorbed is

296 Samples were dissolved in water and acidified with HNO3.

297 50-60% RH and when the aerosol particles are acidified with sulfuric acid but stops entirely only und

298 Winemaking of musts acidified with up to 3g/L of gypsum (CaSO4 2H2O) and tar

299 Failure of the ECV to acidify would prevent both upregulation of the T3SS and

300 Inclusion of MTGase into acidified yogurt drinks reduces the serum separation wit