ライフサイエンスコーパス: activity against

1 (RIKTVTSFDLPALRWLKL) exhibited antimicrobial activity against 16 different bacteria, including pathog

2 he Escherichia coli homologue YjhC displayed activity against 2,7-anhydro-Neu5Ac and that E. coli cou

3 solubilized chitosan possessed antibacterial activities against 3 single-species biofilms: Streptococ

4 d engineered three mutant CARs with enhanced activity against 6-ACA.

5 screened for both agonistic and antagonistic activities against a panel of 168 G protein-coupled rece

6 el siderophore-conjugated cephalosporin with activity against a broad array of multidrug-resistant (M

7 in whose alkyl substituent conveys excellent activity against a broad spectrum of ESKAPE pathogens an

8 nalog that has demonstrated potent antiviral activity against a broad spectrum of viruses in multiple

9 We demonstrate that PyoG has broad killing activity against a collection of clinical P. aeruginosa

10 broad as an anti-influenza drug and exhibits activity against a diverse array of clinically relevant

11 he innate immune response, exhibit antiviral activity against a multitude of viruses including VEEV.

12 iparasitic agent with demonstrated antiviral activity against a number of DNA and RNA viruses, includ

13 otoxicity, potent broad-spectrum sterilizing activity against a panel of gram-positive and gram-negat

14 faecal isolate, which exhibits antimicrobial activity against a panel of gut and food isolates by vir

15 atterns of hemagglutination inhibition (HAI) activity against a panel of H1N1 influenza viruses.

16 was assessed for hemagglutination inhibition activity against a panel of historical seasonal-like and

17 domestic chicken and describe its antiviral activity against a prototypical avian retrovirus, avian

18 development of a potent cidal compound with activity against a range of clinically relevant L. donov

19 he PTPRU-D1 displays no detectable catalytic activity against a range of phosphorylated substrates an

20 UCH3 also possesses a broad deubiquitylation activity against a range of substrates that link ubiquit

21 tional antibiotics and displays bactericidal activity against a wide phylogenetic spectrum of pathoge

22 so show effective, broad-spectrum fungicidal activity against a wide range of fungal pathogens of mai

23 es but instead exerts a potent antimicrobial activity against a wide range of rainbow trout pathogens

24 e characterized in vitro for their antitumor activity against A549, PC-3, and HCT-116 cancer cell lin

25 eightlifting model, which elicits squat-like activities against adjustable load during feeding, to in

26 he alpha-TCsNe exhibited enhanced antifungal activity against aflatoxin secreting strain of Aspergill

27 tives (26a-c), which possess high inhibitory activity against ALK2, excellent selectivity, and superi

28 tly, CLR01 and CLR05 display broad antiviral activity against all enveloped viruses tested, including

29 these antimicrobials had expressed antiviral activity against all five viruses through all phases of

30 nzymatic characterization of PyrKII revealed activity against all NDPs and dNDPs tested, suggesting t

31 s exhibited strong quorum sensing inhibition activity against all S. aureus accessory gene regulator

32 ssential oils exhibited strong antimicrobial activity against all test-microorganisms.

33 Moreover, root samples revealed activity against all tested cell lines regardless of fer

34 mTOR/PI3K inhibitors demonstrated antitumour activity against all xenografts tested.

35 pha-crystallin domain retains some chaperone activity against amyloid formation, the flanking domains

36 nisms by which sHSPs achieve their chaperone activity against amyloid-forming clients and how cells d

37 mong these, compound 40 potentiates imipenem activity against an NDM-1-producing E. coli clinical str

38 nation of high conductance, high efficiency, activity against an unmodified vertebrate channel, and c

39 cium-dependent antibiotic (CDAs) family with activity against antibiotic-resistant pathogens.

40 R2-expressing cancer cells, while showing no activity against antigen-negative cells.

41 sign approach and evaluated their inhibition activities against APN.

42 ntimalarial combination therapy that retains activity against artemisinin-resistant parasites.

43 C-induced MM-specific CD8(+) CTL and NK cell activity against autologous tumor cells.

44 llus) for the first time and demonstrate its activity against avian sarcoma and leukosis virus (ASLV)

45 Such derivatives showed high activity against axenic amastigotes, and among them, com

46 odification in the apicoplast; mimicking its activity against bacteria.

47 These macrophages acquire cytocidal activity against beta-cells via nitric oxide and induce

48 lar chaperone that exhibits anti-aggregation activity against bile salt-induced protein aggregation.

49 y against planktonic cultures, garlic has no activity against biofilms.

50 st regimen to demonstrate improved antitumor activity against BMs in patients with HER2-positive brea

51 t promising candidate with potent inhibitory activities against both PARP-1/2 and PI3Kalpha/delta wit

52 t that the small-molecule CX-6258 has potent activity against both RMi-sensitive (RMS) and -resistant

53 exhibiting broad hemagglutination inhibition activity against both seasonal and pandemic H1N1 influen

54 verage size of 140 nm and with antimicrobial activity against both sensitive and resistant Gram posit

55 olecules possess excellent anti-tuberculosis activity against both the drug-susceptible (MIC = 0.0039

56 brids with good structure-dependent in vitro activity against both the hepatic and erythrocytic stage

57 formulations, lefamulin has potent in vitro activity against both typical and atypical CABP pathogen

58 identified to possess excellent and balanced activities against BRD4 BD1 (IC(50) =11 nm) and HDAC1 (I

59 30 displayed a broad-spectrum antifilovirus activity against Bundibugyo, Tai Forest, Reston, and Men

60 in (MIC(50) = 0.06 mug/ml), exhibited potent activity against C. difficile strains.

61 , but only the active peptide displayed this activity against capsulated K. pneumoniae Unexpectedly,

62 am is a combination antimicrobial agent with activity against carbapenemase-producing Enterobacteriac

63 mice pretreated with DARA, and enhanced ADCC activity against CD38-expressing MM cell lines and prima

64 ors were screened to assess their inhibitory activities against cellular and humoral immune responses

65 rase and topoisomerase IV and display potent activity against ciprofloxacin-resistant Gram-negative p

66 activating group and exhibits broad spectrum activity against class A, C, and D serine beta-lactamase

67 ural product that shows potent antibacterial activity against clinically important pathogens.

68 Activity against CMV-infected target cells was assessed

69 n biomodification, which includes protective activity against collagen degradation and reinforcement

70 They have shown in vitro antifungal activity against Colletotrichum acutatum and Colletotric

71 sent work aimed to: (i) determine antifungal activity against Colletotrichum gloeosporioides and Peni

72 le for their demonstrated in vitro antiviral activities against COVID-19.

73 In conclusion, PGG exhibits antimicrobial activity against CRAB, but due to known pharmacological

74 ation as a possible mode of action for PGG's activity against CRAB.

75 oth nano MgO and micron MgO had bactericidal activity against Cu-tolerant strains in vitro, only nano

76 broad-spectrum prophylactic and therapeutic activity against currently circulating influenza viruses

77 QACs were more effective than APCs and had activity against cysts.

78 Maribavir is a benzimidazole riboside with activity against cytomegalovirus (CMV).

79 ion, DAH also exhibits promiscuous azidation activity against dechloroacutumine.

80 The activity against dengue protease was in general higher t

81 t on total phenolics contents and scavenging activities against different free radicals (DPPH, ABTS(+

82 membrane fusion, with a range of inhibitory activities against different HIV-1 Env isolates.

83 tivity that possesses unusual broad-spectrum activity against diverse paramyxoviruses including respi

84 UV-4B has broad-spectrum antiviral activity against diverse viruses including dengue and in

85 EGC and its esters showed radical scavenging activities against DPPH radical and ABTS radical cation.

86 ings reveal that Cas12a has multiple nicking activities against dsDNA substrates and that these activ

87 Citrocin has moderate antimicrobial activity against E. coli and Citrobacter strains.

88 Plain TVO showed the highest antimicrobial activity against E. coli, S. aureus, and S. typhi in in

89 The resulting nanocapsules had antimicrobial activity against E. coli, which could be extended to dev

90 lass II transactivator (CIITA) has antiviral activity against EBOV.

91 inflammation but it has no direct antiviral activity against ECTV.

92 al peptides have been identified that retain activity against encapsulated K. pneumoniae, suggesting

93 al hit series eliciting potent antibacterial activities against Enterobacteriaceae and Pseudomonas ae

94 e considered adequate for redirected killing activity against Env-expressing target cells but began t

95 antiviral action suggests potentially broad activity against enveloped viruses.

96 GA was also reported to have activity against Escherichia coli and Staphylococcus aur

97 assay was used to analyse the antimicrobial activity against Escherichia coli ATCC 25922 and Staphyl

98 Ellisiiamide A demonstrated Gram-negative activity against Escherichia coli BW25113, which is the

99 This yielded nine antibiotics with activities against ESKAPE pathogens as well as Mycobacte

100 dition (T9 CAR-T) have an enhanced antitumor activity against established tumors.

101 on cheminformatics/data mining analyses and activity against evolutionarily distant Trichuris muris

102 ow-derived and human blood-sorted eosinophil activity against FITC-linked fibrinogen substrates.

103 topiperazines (ETPs) and evaluation of their activity against five human cancer cell lines.

104 miluminescence technique, and the inhibitory activity against formation of fluorescent advanced glyca

105 er, synthetic PvD(1) retained the biological activity against four different Candida species and show

106 Antibody-dependent cell-mediated cytotoxic activity against FRalpha is also associated with prolong

107 synthesize potent inhibitors with selective activity against fungal Hsp90 isoforms over their human

108 Relative to DCV, 13 improved activity against genotype 1a (gt1a) and gt1b NS5A varian

109 otypes showed highly-specific neutralization activity against GII.4 and GII.6 noroviruses.

110 ZIKV also displays therapeutic oncolytic activity against glioblastoma (GBM) stem cells (GSCs).

111 show that Gga-AvBD11 displays antimicrobial activities against gram-positive and gram-negative bacte

112 l (CFDC) is a siderophore cephalosporin with activity against Gram-negative bacterial species that ar

113 ntravenous cephalosporin with broad in vitro activity against gram-positive (including methicillin-re

114 m-negative ESKAPE pathogens, and antibiofilm activity against gram-positive and gram-negative biofilm

115 hile bioactivity assays showed antimicrobial activity against Gram-positive bacteria and fission yeas

116 efiderocol does not have clinically relevant activity against Gram-positive or anaerobic organisms.

117 r neutralizing and stronger cross-protection activities against H1, H3, H5, and H7 strains and subtyp

118 y, 53C10, exhibiting a potent neutralization activity against H1N1 influenza viruses.

119 long-acting HIV drug formulations with dual activity against HBV would be transformative and have a

120 for in vitro antiviral and antiproliferative activity against HCMV and glioblastoma cell line (GBM6),

121 and not lysine, reactivity was important for activity against HCMV.

122 atment and prevention efforts, their lack of activity against hepatitis B virus (HBV) could limit the

123 punicatannin C induced a moderate cytotoxic activity against HepG2 and MCF-7 cell lines.

124 zation of bispecific CAR-T cells with robust activity against heterogeneous multiple myeloma (MM) tha

125 Brincidofovir has high in vitro activity against HHV-6B and other DNA viruses, but its i

126 umulate in E. coli and possess antibacterial activity against high-priority Gram-negative pathogens.

127 reatment for histoplasmosis; it has in-vitro activity against Histoplasma capsulatum and has shown su

128 d development of long-acting drugs with dual activity against HIV and HBV exists.

129 ng human antibodies (bNAbs) with exceptional activity against HIV-1 are currently being tested in HIV

130 marily guided by their in vitro neutralizing activity against HIV-1 Env pseudotyped viruses.

131 chemotherapy, was prepared and screened for activity against HIV-1 infection in cell culture.

132 ue, NBD-14189 (Ref1), which showed antiviral activity against HIV-1(HXB2), with a half maximal inhibi

133 ally, TAK1 inhibitor Takinib shows promising activity against HL in vitro and in a xenograft mouse mo

134 We show that PG naturally exerts antiviral activity against HSV-1 and HSV-2 infections.

135 formis KT921419) displayed strong anticancer activity against HT-29 colon cancer cell line.

136 y acting cellular ion channel inhibitors for activity against human cytomegalovirus (HCMV) and identi

137 saccharide trehalose, which showed antiviral activity against Human Cytomegalovirus (HCMV) in our pre

138 referred to as XTC) appear to retain modest activity against human immunodeficiency virus-1 with the

139 wbacks including off-target promiscuity, low activity against human nNOS, and only modest selectivity

140 l compound 4 (V2a) demonstrated antagonistic activities against hypocretin (orexin) receptor 2.

141 se inhibitor relebactam can restore imipenem activity against imipenem-nonsusceptible gram-negative p

142 M3 oligomerization and reduced its antiviral activity against Influenza A virus.

143 ding their cytotoxicity and virus-inhibiting activity against influenza virus A/Puerto Rico/8/34 (H1N

144 e feedback amplifiers of neutrophil effector activity against inhaled mold conidia.

145 isin-A, the BP(SCSK) lantibiotic has reduced activity against intestinal commensal bacteria.

146 osphate is required for potent and selective activity against intracellular Burkholderia In a murine

147 . tb in vitro at 10 mug/ml, whereas, similar activity against intracellularly growing M. tb was obser

148 ective TAK1 inhibitor that has only marginal activity against IRAK-4.

149 we showed that edited miR-200b has weakened activity against its target gene ZEB1 in thyroid cancer

150 en investigated for their in vitro cytotoxic activity against Jurkat, K562, U937, and HL60 tumor and

151 Compound 5 showed potent in vivo activity against L. infantum.

152 ivering IMP-105 (43), a compound with modest activity against Leishmania donovani intracellular amast

153 ety of cancers, and with particularly strong activity against LSCs.

154 ide and several congeners to determine their activity against mammalian RyR2.

155 reviously described compounds with antiviral activity against mammarenaviruses for their ability to i

156 ase that has been shown to have bactericidal activity against many pathogens, including Pseudomonas a

157 icriviroc-resistant HIV-1s, but did not show activity against maraviroc (MVC)-resistant HIV-1.

158 of broad-spectrum antibacterial agents with activity against MDR Gram-negative bacteria, including W

159 e and levofloxacin have a promising in vitro activity against MDR-E. coli.

160 -principle that FDA-approved inhibitors with activity against MEKK2 can ameliorate NF1 skeletal patho

161 tinib is a multikinase inhibitor with potent activity against MET(3).

162 Olaparib has antitumour activity against metastatic castration-resistant prostat

163 er exploited in photocatalytic antibacterial activity against methicillin-resistant Staphylococcus au

164 One dimer has activity against methicillin-resistant Staphylococcus au

165 omycin (DAP) results in synergistic in vitro activity against methicillin-resistant Staphylococcus au

166 on at the C-terminus is required for hGBP1's activity against microbial pathogens, as well as for its

167 can be tuned for broad-spectrum or specific activity against microorganisms.

168 and shed light on its previously undescribed activity against mobile genetic elements, such as LINE-1

169 at the NEIL3 GRF domain inhibits glycosylase activity against monoadducts and ICLs.

170 act nanoemulsion showed higher antimicrobial activity against most of the tested pathogens.

171 pressing these scFv variants showed improved activity against mouse and human cancer cell lines defec

172 MHMs demonstrated excellent bactericidal activity against MRSA at concentrations >= 10% of honey,

173 The TZP combination lacks activity against MRSA, yet it synergized with compound 7

174 azolin and ertapenem provides potent in vivo activity against MSSA beyond what is predicted in vitro

175 The compound shows activity against Mtb H37Rv residing in macrophages.

176 optimal lead compound with potent inhibition activities against mTOR and HDAC1 with half-maximal inhi

177 e (Leucophyllum frutescens) has demonstrated activity against multi-drug-resistant tuberculosis.

178 s urgent to find new antibiotic classes with activity against multidrug-resistant (MDR) Gram-negative

179 , an antibiotic with broad-spectrum in vitro activity against multidrug-resistant and extensively dru

180 in has been shown to have a wide spectrum of activity against multidrug-resistant Gram-negative bacte

181 a search for new antimicrobials with potent activity against multidrug-resistant gram-negative patho

182 of FabI inhibitors with clinically-relevant activity against multidrug-resistant S. aureus.

183 enzymes and exhibited good antiproliferative activity against multiple cancer cell lines.

184 nd F0045(S) exhibits in vitro neutralization activity against multiple H1N1 and H5N1 strains.

185 a universal vaccine with broadly protective activity against multiple influenza strains and subtypes

186 nana lectin (H84T), to retain broad-spectrum activity against multiple influenza strains, including p

187 geting B-cell maturation antigen (BCMA) have activity against multiple myeloma, but improvements in a

188 044 peptide also exhibited potent fungicidal activity against multiple plant fungal pathogens, includ

189 Pentyl-P14 exhibited excellent antibacterial activity against multiple strains of pathogenic bacteria

190 t improved expansion and increased cytotoxic activity against multiple tumor cell lines when maintain

191 Both exhibited high antimicrobial activity against multiresistant Staphylococcus aureus MI

192 ontaining hexacyclic framework that exhibits activity against Mycobacterium.

193 that auranofin exhibited rapid bactericidal activity against N. gonorrhoeae.

194 ariants might exist with enhanced, selective activity against neurodegenerative disease substrates.

195 uated, and they exhibit potential biological activity against non-communicable diseases.

196 veiling several that exert similar or higher activity against nSMase2 with favorable pharmacokinetic

197 C, which has been shown to have anti-tumour activity against NTRK gene fusion-positive solid tumours

198 ince then, viperin has been shown to possess activity against numerous viruses via multiple proposed

199 s faecalis although PSO had an antimicrobial activity against only Staphylococcus aureus.

200 colorectal cancer and may exhibit antitumor activity against other tumor types.

201 y of naive OT-1 T cells to develop antitumor activity against ovalbumin-expressing melanoma.

202 rom the current DBOs in restoring carbapenem activity against OXA-CRAB as well as SBL-carrying CRE pa

203 transmission, and also showed parasiticidal activity against P. berghei and P. knowlesi Hence, our d

204 These data together with analysis of activity against parasites collected from patients in th

205 en earlier reported to possess antimicrobial activity against pathogenic bacteria, fungi, and parasit

206 ylococcus sp. and B. subtilis, and exhibited activity against pathogens only in the presence of TTC,

207 This material has strong antibacterial activity against periodontal pathogens such as Streptoco

208 y, exhibited metabolic stability, and lacked activity against phosphodiesterase-4.

209 ytotoxicity, but also reduced its antibiotic activity against planktonic cells due to a reduced cell

210 nce of garlic in the mixture can explain the activity against planktonic cultures, garlic has no acti

211 Several of these compounds exhibit activity against planktonic M. abscessus and M. tubercul

212 We screened ~1.8 million small molecules for activity against Plasmodium vivax (P. vivax) NMT.

213 annii (MIC 64-256 ug/mL), and also exhibited activity against Pseudomonas aeruginosa (MIC 16 ug/mL) a

214 primary African isolates differs from their activity against pseudovirus panels.

215 CAR-T cells have shown encouraging activity against recurrent and refractory diffuse large

216 vaccine plus pembrolizumab showed antitumour activity against recurrent or advanced cervical cancer.

217 ase inhibitor combination that often retains activity against resistant Pseudomonas aeruginosa.

218 ntimicrobials, old or new, maintain reliable activity against resistant S. maltophilia The role of mi

219 compound with a broad spectrum of antiviral activities against RNA viruses, including severe acute r

220 RDV shows broad-spectrum antiviral activity against RNA viruses, and previous studies with

221 ot the cross-reactive mAbs, had neutralizing activity against RV-A15.

222 gues displayed up to 32-fold increase of the activity against S. aureus and 16- to 64-fold against E.

223 acts were also screened for quorum quenching activity against S. aureus, including direct protein out

224 producing oral commensal, has antimicrobial activity against S. mutans.

225 Nanobody-Fc fusions showed neutralizing activity against SARS-CoV-2 (4-6 nM for H11-H4, 18 nM fo

226 d donor sera exhibited specific neutralizing activity against SARS-CoV-2 and SARS-CoV-2 S pseudotypes

227 her with reported therapeutic compounds with activity against SARS-CoV-2 and/or other CoVs.

228 While ivermectin's activity against SARS-CoV-2 is currently under investiga

229 Remdesivir has potent in vitro activity against SARS-CoV-2, but it is not US Food and D

230 ested that hydroxychloroquine had biological activity against SARS-CoV-2, potentially permitting its

231 l activities, and they also show substantial activity against schistosomes-another hemoglobin-degradi

232 la-Phe-Ser (SVAFS) displayed robust blocking activity against serpin-3.

233 cteria (Eleftheria terrae), displayed potent activity against several Gram-positive pathogenic bacter

234 ealed that gladiostatin, which has promising activity against several human cancer cell lines and inh

235 25 lysine residues with known antimicrobial activity against several human microbial pathogens.

236 er, when we tested the potential for broader activity against several other human pathogenic viruses,

237 t analogue, PK150, that showed antibacterial activity against several pathogenic strains at submicrom

238 One of these analogues has excellent activity against several streptogramin-resistant strains

239 n identified a benzamide small molecule with activity against small cell lung cancer cells.

240 ed multifactorially with their antibacterial activity against Staphylococcus aureus and Pseudomonas a

241 onas aeruginosa suppresses its antimicrobial activity against Staphylococcus aureus, a common pathoge

242 PSOP displayed inhibitory activity against Staphylococcus aureus, Pseudomonas aeru

243 Auranofin's in vitro activity against strains of S. aureus (including MRSA) w

244 2-OH showed antimicrobial activity against strains tested.

245 was sufficient to yield plasma-neutralizing activity against streptococcal superantigens.

246 me powder exhibited potent antihyperglycemic activity against sugar-induced postprandial hyperglycemi

247 eishmania major PTR1 inhibition and in vitro activity against T. brucei and amastigote Leishmania inf

248 a potent TbrPDEB1 inhibitor with interesting activity against T. brucei in a phenotypic screen.

249 found to synergistically improve baculovirus activity against T. ni.

250 Isoniazid 10-15 mg/kg daily had similar activity against TB strains with inhA mutations as 5 mg/

251 s (S-MGBs), which display excellent in vitro activities against the principal causative organisms of

252 ives displayed potent and selective in vitro activity against the amastigote stage of L. infantum whi

253 endowed with potent and selective inhibitory activity against the cancer-related human carbonic anhyd

254 CS MOFs displays a circa 20-fold increase in activity against the chemical warfare agent simulant dim

255 covalently reactive beta5i inhibitors, whose activity against the constitutive proteasome (c-20S) is

256 The GY1-22 compound displayed an effective activity against the DNAJA1-mutp53(R175H) complex.

257 t the liver stage of the parasite but little activity against the gametocyte stage.

258 The novel opuntisine A showed moderate activity against the Gram-negative bacterium Escherichia

259 The acridones showed mild activity against the human cytomegalovirus.

260 compound 13m revealed its antiproliferative activity against the human glioblastoma cell line (GBM6)

261 tionally modified peptide (RiPP) with potent activity against the human pathogen Clostridium perfring

262 class of heterospirocycles with antimalarial activity against the human protozoan P. falciparum.

263 Investigations of antiviral activity against the human respiratory syncytial virus w

264 this series display sub-micromolar in vitro activity against the intraerythrocytic stage of the para

265 In addition, our hit compounds show good activity against the liver stage of the parasite but lit

266 exposure in mice combined with good in vitro activity against the malaria parasite, which translated

267 was shown to critically modulate inhibitory activity against the Na(+)/K(+) pump.

268 Surprisingly, dose-dependent activity against the nuclease reporter (nuc), which is u

269 ng these data, we prioritized compounds with activity against the parasites and uncovered a pair of p

270 elta and provides a predictive model for the activity against the PI3K isoforms.

271 gues were shown to exhibit potent inhibitory activity against the Plasmodium falciparum cysteine prot

272 ity assays reveal potent but narrow-spectrum activity against the producing strain and its closest re

273 ns, Delta123-HMW, elicits broad neutralizing activity against the seven major genotypes of HCV.

274 interesting functional profile, in terms of activity against the target enzyme and selectivity towar

275 the most potent fluconazole chemosensitizing activity against the test strain (SigmaFICI 0.05) and th

276 cterial assay reveals a strong antibacterial activity against the tested Gram-positive and Gram-negat

277 de and adoptive T-cell therapy, boost T-cell activity against the tumor, but these strategies are not

278 esised and characterised and then tested for activity against the V2, V1a and OT uterine receptors an

279 ecognized MARV GP and possessed neutralizing activity against the virus.

280 ors omapatrilat and sampatrilat possess dual activity against these enzymes by blocking the ACE-depen

281 cacy for endocarditis, and also little or no activity against those bacteria that remain in the mouth

282 centration-dependent manner and demonstrated activity against Trypanosoma brucei rhodesiense bloodstr

283 eveloped compounds show significant cellular activity against Trypanosoma, including the human pathog

284 anid, and linezolid - that have bactericidal activity against tuberculosis and to which there is litt

285 ophages with CARs to direct their phagocytic activity against tumors.

286 size (50 nm) and had a strong antimicrobial activity against twelve common nosocomial pathogenic mic

287 provided quantitative evaluation of compound activity against two key attributes of human sperm funct

288 It displays narrow-spectrum activity against vancomycin-resistant Enterococcus faeci

289 m cation and that C1-CBP-vancomycin exhibits activity against vancomycin-resistant organisms through

290 and 9-positions presented growth inhibitory activities against various human cancer cell lines, incl

291 sing allosteric EGFR degrader with selective activity against various clinically relevant EGFR mutant

292 NVS-CECR2-1 exhibits cytotoxic activity against various human cancer cells, killing SW4

293 collaboration on implementing multisectoral activities against VBDs will continue among TDR, the Swi

294 small molecule, ML336, with potent antiviral activity against VEEV.

295 These derivatives retained activity against vicriviroc-resistant HIV-1s, but did no

296 Here, we report its activity against viral replication.

297 lectin that has shown in vivo broad-spectrum activity against viruses, including severe acute respira

298 an have a significant impact or abolish diet activities against WCR.

299 nformation to achieve improved antibacterial activity against wild-type E. coli.

300 boswitch, from a compound lacking whole-cell activity against wild-type GN pathogens into a compound