ライフサイエンスコーパス: activity control

1 itch module for low-baseline and robust Cas9 activity control.

2 e been developed to achieve on-demand enzyme activity control.

3 l requirements for membrane localization and activity control.

4 Spar exhibit defects in sleep and circadian activity control.

5 ting the MID1-PP2A protein complex with GLI3 activity control.

6 brings essential elements to understand its activity control.

7 expected spatial separation of stability and activity control.

8 -treated mice without wheel access served as activity controls.

9 advanced inflammatory activity and 220 mild activity controls.

10 diated inhibition of renal sympathetic nerve activity (control = 12 +/- 1 min; RVLM-strychnine = 5.1

11 y decreased baseline renal sympathetic nerve activity (control, 68.5+/-7.1% of Max; 10(10) particles

12 altered, our results suggest that E protein activity controls a novel checkpoint that regulates the

13 We propose that PLK1 activity controls a polarity checkpoint and compensates

14 mitter release, indicating that postsynaptic activity controls a retrograde signal that regulates pre

15 coding level or sparseness of these neurons' activity controls a trade-off between generalization and

16 To analyse in detail the performance of this activity control algorithm, we used specialised in vitro

17 s offer molecular insight into how autonomic activity controls alveolar formation.

18 oreactors for two-phase reactions with water activity control; and environmental bioreactors.

19 re, we report how Src family tyrosine kinase activity controls apCAM-mediated growth cone steering by

20 tightly regulated molecules known: neuronal activity controls Arc mRNA induction, trafficking and ac

21 n (1:1:1) to receive routine polio programme activities (control, arm A), additional interventions wi

22 he opposite phenotype, indicating that cup-5 activity controls aspects of endocytosis.

23 n three transgenic mouse lines, two with Cre activity controlled at the transcriptional level (Ahcre,

24 results suggest a model whereby Mek1 kinase activity controls axial element assembly by regulating t

25 Understanding how dynamic changes in brain activity control behavior is a major challenge of cognit

26 upling (NVC) is the process whereby neuronal activity controls blood vessel diameter.

27 We show balanced Rac1 activity controls both leading edge protrusion and point

28 the expression of POLQ and, therefore, TMEJ activity, controlling both stability and integrity of br

29 and Ste2p required the vacuolar proteolytic activities controlled by the PEP4 gene.

30 ceptors will help identify the physiological activities controlled by these receptors.

31 action prevents the regulation of BK channel activity controlled by changes in actin cytoskeletal dyn

32 lex ATP-dependent DNA helicase with nuclease activity controlled by Chi recombination hotspots (5'-GC

33 el enhancer has been characterized, with its activity controlled by Dorsocross and Tinman transcripti

34 ecular switches, with target protein-binding activity controlled by prior binding to specific input s

35 nregulation reflects a decrease in endocytic activity controlled by Rho family GTPases, especially Cd

36 tations in distinguishing FAA from locomotor activity controlled by the primary circadian pacemaker i

37 shock might be regulated by changes in PP2A activity controlled by the SET protein.

38 - L-type-Ca(2+) channels and D2-autoreceptor activity, controlled by NCS-1, and indicate that this ad

39 ivo cellular experiments indicate that TIM-1 activity controls CD4(+) T cell activity.

40 s provide a mechanism by which PP2A and DAPK activities control cell adhesion and anoikis.

41 er, both the level and duration of signaling activity control cell fate choices only by changing the

42 While iron chaperone activity controls cell cycle progression and suppression

43 These results show that CDK5 activity controls cell motility and metastatic potential

44 cterization of this mutant showed that ClpXP activity controls cell size and is required for growth a

45 est that the balance between Akt and caspase activity controls cell survival.

46 Thus, YAP/TAZ activity controls chondrocyte proliferation in vitro, po

47 embrane helices, is subject to a complicated activity-control circuit involving two other proteins wi

48 el, we find that Protein phosphatase 1 (Pp1) activity controls collective cell cohesion and migration

49 MS/CIS with newer DMTs led to better disease activity control compared to injectables, supporting gre

50 t to cell culture systems, cortical synaptic activity controls CRE-mediated gene expression without a

51 ck, and from BCI/BMI studies in which neural activity controls cursors or peripheral devices.

52 l particles to introduce chiral rollers with activity-controlled curvatures of their trajectories and

53 ur results illustrate how a gradient of MAPK activity controls differential gene expression and, thus

54 gradient of cell movement, with WNT and FGF activities controlling direction and velocity, respectiv

55 The ATPase activity controls dissociation of an MVH complex contain

56 chanism underlying precise MCAK depolymerase activity control during mitosis remains elusive.

57 tor (TCR)-dependent regulatory T cell (Treg) activity controls effector T cell (Teff) function and is

58 er supporting the notion that AIG1 and ADTRP activity control endogenous FAHFA levels.

59 its Ras guanosine triphosphatase -activating activity, controls ERK1/2-dependent fibroblast growth fa

60 , by pathways that stimulate phospholipase C activity, controls excitability throughout the nervous s

61 ta-activating kinase 1 (TAK1) and p38, whose activity controls expression of numerous metastasis prom

62 nism by which cell spreading and RhoA GTPase activity control FA formation through YAP to stabilize t

63 The results suggest that sympathetic activity controls fat-induced satiety by enabling the co

64 We found that PAM-beta'2 DANs activity controls feeding rate and satiation: closed-loo

65 Because plasmin activity controls fibrinolysis in a variety of pathologi

66 We propose that neuronal activity controls filopodial motility in a developmental

67 barrier formation in which epidermal mTORC2 activity controls FLG processing and de novo epidermal l

68 esults suggest the importance of prestimulus activity control for improving sensory coding within the

69 tic evidence that PTEN's protein phosphatase activity controls FYN kinase function in glioma cells an

70 tructs, we found that Akt (protein kinase B) activity controlled gap junction stability and was neces

71 Neuronal NMDA receptor activity controls glial motility through intercellular a

72 However, the mechanism by which neuronal activity controls glucose influx via GLUT3 is unknown.

73 lease, but the mechanism by which electrical activity controls GnRH secretion is not well characteriz

74 An OT group, a social activity control group, and a nontreatment control group

75 No mutant alleles were found in the high activity control groups.

76 emory formation to decision making and motor activity control--have inspired their re-creation in a w

77 in suggests that it may be involved in motor activity control in basal ganglia as well as higher cent

78 Intracellular metalloprotease activity controls intraneuronal Abeta aggregation and li

79 We show that AKAP79/150-anchored PKA activity controls Kv4.2 surface expression in heterologo

80 n the chick limb bud, the zone of polarizing activity controls limb patterning along the anteroposter

81 se exciting results and discuss how synaptic activity controls local translation, the proteins that a

82 LRRK2 Roc-COR tandem domain exhibits GTPase activity controlling LRRK2 kinase activity via an intram

83 We propose that LKB1 kinase activity controls membrane dynamics through FAK since lo

84 regulator of midzone plus-end dynamics whose activity controls midzone length but not stability.

85 promoting factor (MPF), the major enzymatic activity controlling mitotic cycles in frog eggs, early

86 As a motor activity control [motor control (MC)], lesion and sham a

87 s" in the hippocampus of rodents to cortical activity controlling movement, temporal sequence generat

88 trictive Mediterranean diet without physical activity (control; n = 201) on a set of HDL functional t

89 e randomized 296 patients to normal physical activity (control; n=145) or walking exercise (n=151); 2

90 Here we demonstrate that activity controls NMDAR synaptic accumulation by regulat

91 ipheral, segmental, and supraspinal neuronal activities control nociceptive processing at all levels

92 center and program characteristics, clinical activities, control of clinical activities, and needs an

93 pendent protein kinase II (CaMKII)-dependent activity control of parvalbumin (PV)-expressing cortical

94 een reported to be involved in recombination activity, control of gene expression of nearby gene(s) (

95 hanism by which autophagy regulates neuronal activity: control of intrinsic excitability via the regu

96 3 kind acts for themselves, or to list daily activities (control), on one day per week over 4 weeks.

97 reprogramming of an organizing center whose activity controls outgrowth and patterning of the mid an

98 pylase Dop, affording a rapid and reversible activity control over Mpa function.

99 Complex II (CII) activity controls phenomena that require crosstalk betwe

100 taxin (ATX), through its lysophospholipase D activity controls physiological levels of lysophosphatid

101 anti-silencer (pp52 anti-NRE) with opposing activities controlling pp52 gene expression.

102 ial activation and destruction of CDK-cyclin activities controls progression through the cell cycle.

103 Wnt16, which is also downstream of muscle activity, controls proliferation and migration, but play

104 s, and increase or decrease of KCNQ5 channel activity controlled release probability through alterati

105 These data help explain how CDK activity controls replication initiation and suggest tha

106 rogenase and possesses glutathione reductase activity controlling respiratory chain functions and glu

107 ion-specific, axon repulsive and stimulatory activities control retinal axon patterning in the embryo

108 reatly improve our understanding of how PARG activity controls reversible protein poly(ADP-ribosyl)at

109 in the cNTS during dehydration, sympathetic activity control reverts back to forebrain regions.

110 tivity of Runx3 expression, and its level of activity, control sensory afferent targeting in the deve

111 at temporal coordination of neuronal spiking activity controls signal transmission and behavior.

112 Thus, Clr4 activity controls siRNA amplification from the different

113 acetylcholine orchestrate brain oscillatory activity, control sleep architecture and microarchitectu

114 f spatial and temporal control of the kinase activity controlling spatial patterning during multicell

115 ition, we have limited knowledge of how PLK4 activity controls specific steps in centriole formation.

116 targeting technologies for carrier EVs, and activity control strategies for pathological EVs.

117 Furthermore, neuronal activity controls synaptic AMPA receptor trafficking, an

118 We found that sensory-independent electrical activity controls synaptic maturation in IHCs.

119 suggest that dopamine together with neuronal activity controls synthesis of plasticity-related protei

120 CD39 enzymatic activity controlled T cell cytokine production.

121 Whereas previous work has focused on activities controlling TGF-beta signaling, more recent s

122 ous studies have investigated the regulatory activities controlling TGF-beta signaling, there is rela

123 tion and subsequent reactivation of cellular activities controlling the cycling of Golgi components i

124 ntial phases of Hox-c protein expression and activity control the columnar differentiation of spinal

125 report that rhythmic travelling waves of Erk activity control the growth of bone in time and space in

126 tica to the ocean, and fluctuations in their activity control the mass balance of the ice sheet.

127 cetylcholine-dependent spontaneous bursts of activity control the outgrowth of receptive-field areas

128 gulated by LPC, rather than direct agonistic activity control the signaling responses of murine G2A t

129 lobal levels of adhesion strength and myosin activity control the stability of the stationary state:

130 preferentially the conditioned neurons whose activity controlled the BMI actuator during training.

131 this is achieved in part by postmeiotic gene activity controlling the development of the haploid fema

132 arm temperature-mediated regulation of SLOMO activity controls the abundance of hypocotyl growth regu

133 nhibitor of IRAK4, we show that IRAK4 kinase activity controls the activation of interferon regulator

134 We conclude that although Nkx2-3 activity controls the addressin balance of HEVs in GALT,

135 aded by the proteasome, indicating that Rbd2 activity controls the balance between SREBP activation a

136 sence of the substrate, whereas the cellular activity controls the degree of the labeling.

137 liated cells, we show that GMAP210 tethering activity controls the delivery of LAT to the cilium.

138 at after postnatal day 3, glutamate-mediated activity controls the development of their axons and den

139 show that spatial regulation of ADF/cofilin activity controls the directional responses of the growt

140 ng cultured neurons have suggested that Cdk5 activity controls the efficiency of neurite extension [3

141 Collectively, these data showed that PAP activity controls the expression of PSS for membrane pho

142 Thus, telomerase activity controls the glycolytic pathway, potentially al

143 Thus, spatiotemporal ULP-4 activity controls the HMGS-1 sumoylation state in a mech

144 r olive is thought to act as a teacher whose activity controls the induction of motor learning.

145 Its activity controls the maternal decidual response at earl

146 we show in Trypanosoma brucei that Aurora B activity controls the metaphase-to-anaphase transition t

147 highlight how the E-cadherin-dependent EGFR activity controls the migration mode of collective cell

148 ntegration of Bmp4 signaling and Gata factor activity controls the progression of hematopoiesis, as e

149 In this process, Lkb1 activity controls the progression of mitotic chondrocyte

150 Thus, high-frequency neuronal activity controls the ratio of extracellular proBDNF/mBD

151 During postnatal development, neuronal activity controls the remodeling of initially imprecise

152 We propose that a graded distribution of BMP activity controls the specification of several cell type

153 IRE1alpha endoribonuclease activity controls the stability of mRNAs involved in the

154 In addition, CK2 activity controls the subcellular organization of indivi

155 er understand how this intrinsic oscillatory activity controls the susceptibility of the brain to sti

156 Caspase-8 activity controls the switch from cell death to pyroptos

157 We propose Cdk1 activity controls the timing of telomere elongation by r

158 ghly influenced by deregulated TCR/PLCgamma1 activity, controlling the biology of these lesions.

159 , highly influenced by deregulated TCR/PLCy1 activity, controlling the biology of these lesions.

160 has been reported effective in promoting OER activity, controlling the PCET process by tuning the int

161 We show that PP1beta, by regulating myosin activity, controls the generation of the polarizing sign

162 kinetics of their formation and defining the activities controlling their metabolism.

163 fluxes integrate mitochondria into cellular activities, controlling their volume homeostasis and str

164 ich to understand how the dynamics of neural activity control this search behaviour.

165 reveals how spatiotemporal patterns of gene activity control tissue shape by introducing several typ

166 add another previously unrecognized layer of activity control to this important regulatory protein fa

167 genome is recombinogenic, with DNA exchange activity controlled to a large extent by nuclear gene pr

168 complex animal behaviors depends on precise activity control tools, as well as compatible readout me

169 Correspondingly, aIC NTS circuit activity controls vigor, effort, and striatal dopamine r

170 , our results suggest that WAT hematopoietic activity controls WAT inflammatory processes and also su

171 That is, PLC activity controls "when," but not "how," to act.

172 Motor activity control within the cell involves on/off switche