ライフサイエンスコーパス: acute-phase protein

1 hepatic cells with the characteristics of an acute phase protein.

2 iron homeostasis, in addition it acts as an acute phase protein.

3 egulation of inflammation and immunity by an acute-phase protein.

4 EIU), which suggests that PEDF is a negative acute-phase protein.

5 ed by hepatocytes with characteristics of an acute-phase protein.

6 regulated by proinflammatory cytokines as an acute-phase protein.

7 physiological regulator of angptl4, another acute-phase protein.

8 n-6 is also responsible for the synthesis of acute phase proteins.

9 nd type II (haptoglobin, alpha1-antitrypsin) acute phase proteins.

10 that this effect may limit the synthesis of acute phase proteins.

11 rs, proinflammatory cytokine production, and acute phase proteins.

12 d no significant effect on concentrations of acute phase proteins.

13 and induction of a characteristic pattern of acute phase proteins.

14 IGF-I/ BP-3 had no effect on type II acute phase proteins.

15 ctor alpha, followed by a decrease in type I acute phase proteins.

16 The complex had no effect on type II acute phase proteins.

17 amination were each associated with elevated acute phase proteins.

18 3 had no effect on interleukin 6 and type II acute phase proteins.

19 e production of IL-6 and the upregulation of acute phase proteins.

20 presence of numerous activated microglia and acute phase proteins.

21 In liver, they regulate the secretion of acute phase proteins.

22 any increase in proinflammatory cytokines or acute phase proteins.

23 ecules and chemokines, oxidative markers and acute phase proteins.

24 s responsible for induction of CRP and other acute phase proteins.

25 the down-regulation of many coagulation and acute-phase proteins.

26 ion correlated with the genomic induction of acute-phase proteins.

27 inol concentrations in the whole group using acute-phase proteins.

28 with none and those with one or more raised acute-phase proteins.

29 f a set of liver-specific proteins named the acute-phase proteins.

30 ear relation of ferritin concentrations with acute-phase proteins.

31 d IL-6 mRNA, which induces the production of acute-phase proteins.

32 he spleen, or cytokine-mediated induction of acute-phase proteins.

33 ositive and decreased expression of negative acute-phase proteins.

34 tenidap decreased plasma levels of IL-6 and acute-phase proteins.

35 hyl groups of N-glycans covalently linked to acute-phase proteins.

36 lutionarily conserved family of inflammatory acute-phase proteins.

37 d with a transient rise in interleukin-6 and acute-phase proteins.

38 onse genes, including those encoding several acute-phase proteins.

39 Thus, acute-phase protein A1AT is a physiological regulator of

40 The acute-phase protein A1AT is an inducer of hepcidin expre

41 Expression of the acute phase protein alpha(2)-macroglobulin is induced in

42 8 g/L), ferritin (3.7 micrograms/L), and the acute-phase protein alpha 1-antichymotrypsin (ACT; 0.06

43 and endotoxin core IgG antibody [EndoCAb]), acute-phase proteins (alpha-2 macroglobulin [alpha-2M],

44 The levels of five acute-phase proteins (alpha-2 macroglobulin, haptoglobin

45 We first examined whether the acute-phase protein, alpha-2 macroglobulin (A2M), a majo

46 relationships between concentrations of two acute-phase proteins, alpha 1-antichymotrypsin (ACT) and

47 okines-CCL2, CCL11, CXCL1, CXCL8 and CXCL10, acute phase proteins-alpha-2M, CRP, growth factors VEGF

48 entrations of plasma retinol and one or more acute-phase proteins (alpha1-acid-glycoprotein, alpha1-a

49 solution; the same ratio to Abeta of another acute phase protein, alpha1-antichymotrypsin, was not ac

50 to the serum concentration of one potential acute phase protein (alpha2 macroglobulin), and albumin

51 Decreases in acute phase protein and proinflammatory cytokine synthes

52 loid cells triggering the release of hepatic acute phase proteins and inducing extravascular manifest

53 y responses, as evidenced by the presence of acute phase proteins and oxidative damage.

54 jective was to examine the relations between acute phase proteins and plasma retinol concentrations i

55 chemokines, oxidation markers, apoptosis and acute phase proteins and the levels of CD68 positive mac

56 lso support the idea that soluble CD14 is an acute-phase protein and that hepatocytes could be a sour

57 Decreases in circulating plasma markers and acute-phase proteins and an increased baseline effector

58 talyze fluctuations in the concentrations of acute-phase proteins and certain micronutrient biomarker

59 infiltrating Ly6C(pos) macrophages expressed acute-phase proteins and exhibited an inflammatory profi

60 tion and accompanying increases in levels of acute-phase proteins and markers of inflammation and pro

61 e spleen followed by increased production of acute-phase proteins and proinflammatory cytokines.

62 red proteome, including increased amounts of acute-phase proteins and proteins involved in the comple

63 ese data show that GSTs and GCS are negative acute-phase proteins and that decreased GCS activity res

64 aken for serum hepatic constitutive protein, acute phase protein, and proinflammatory cytokine analys

65 n, alpha 1 acid glycoprotein and albumin, an acute phase protein, and subsequent risk of myocardial i

66 The relations among hyporetinolemia, acute phase proteins, and vitamin A status in children a

67 clusters: interleukins, adhesion molecules, acute-phase proteins, and chemokines.

68 d levels of microbial translocation markers, acute-phase proteins, and inflammatory markers were all

69 These proteins included the acute-phase proteins apolipoprotein J, fibrinogen, hapto

70 Nutritional surveys use acute phase protein (APP) biomarkers such as C-reactive

71 C/EBPalpha) is required for the induction of acute phase protein (APP) genes in newborn mice in respo

72 tory reactions, interleukin 6 (IL-6) induces acute phase protein (APP) genes through the Janus kinase

73 IL-1, and TNF-alpha) are potent inducers of acute phase proteins (APP).

74 Whether the positive acute-phase protein (APP) response to infection is affec

75 Fibrinogen-beta (FBG-beta), an important acute-phase protein (APP), is generated by the liver as

76 wing injury or infection, the liver releases acute-phase proteins (APP).

77 Acute phase proteins (APPs) are associated with malaria-

78 ne parameters such as cytokines, chemokines, acute phase proteins (APPs), growth factors, microbial t

79 isk of ASD in relation to levels of neonatal acute phase proteins (APPs), key components of innate im

80 Acute phase proteins (APPs), plasma proteins synthesized

81 cids resembles the amino acid composition of acute phase proteins (APPs).

82 in turn exacerbates OS and the expression of acute phase proteins (APPs).

83 the increased or decreased pool sizes of the acute-phase proteins (APPs) during the metabolic respons

84 acterized by increased circulating levels of acute-phase proteins (APPs) generated by the liver.

85 ies of apparently healthy persons by using 2 acute-phase proteins (APPs), C-reactive protein (CRP) an

86 and increased brain and serum cytokines and acute-phase proteins (APPs).

87 t fevers, leukocytosis, anemia, and elevated acute phase proteins are linked to interleukin (IL)-1 ac

88 ction in edematous malnutrition implies that acute phase proteins are made with a corresponding deple

89 lammation such as inflammatory cytokines and acute-phase proteins are reliably elevated in a signific

90 ytokines, proteases, adhesion molecules, and acute phase proteins as participants in the generation o

91 by cytokines, which signal the synthesis of acute-phase proteins as well as changes in intermediary

92 anifestations of disease, including elevated acute-phase proteins, as well as the local consequences

93 y by measuring changes in plasma retinol and acute-phase proteins associated with subclinical infecti

94 Moreover, these studies have shown that acute phase protein biosynthesis in enterocytes is regul

95 esis of these cytokines by leukocytes and of acute-phase proteins by HepG2 cells.

96 Expression of the acute phase protein C-reactive protein (CRP) is tightly

97 Here we show that the acute phase protein C-reactive protein (CRP), a ligand f

98 Because the acute-phase protein C-reactive protein (CRP) is highly u

99 LytA prevented binding of C1q and the acute-phase protein C-reactive protein to S. pneumoniae,

100 m, longitudinal within-individual changes in acute phase proteins (C-reactive protein [CRP], alpha-1-

101 ed with IGF-I/BP-3, whereas levels of type I acute phase proteins (C-reactive protein, alpha1-acid gl

102 leukin-6 and tumor necrosis factor alpha) or acute-phase proteins (C-reactive protein and serum amylo

103 The acute phase protein, C-reactive protein (CRP), can incre

104 ssed interleukin 1beta-induced expression of acute phase proteins, C-reactive protein, and haptoglobi

105 correlated with plasma concentrations of the acute-phase protein, C-reactive protein (CRP), and the a

106 oclonal antibody immunoassay for the classic acute-phase protein, C-reactive protein (CRP), in serum.

107 The acute-phase proteins, C-reactive protein and serum amylo

108 -4, IL-7, IL-9; myeloid growth-factor: IL-5; acute phase protein: C-Reactive Protein (CRP); immune ce

109 higher levels of proinflammatory cytokines, acute phase proteins, chemokines and cellular adhesion m

110 significant changes in several cytokines and acute-phase proteins: Compared with baseline, levels of

111 Elevated acute phase protein concentrations and infectious diseas

112 ations as a biomarker for sleep restriction, acute phase protein concentrations and malaria infection

113 The study was a nonconcurrent analysis of acute phase protein concentrations and other data from a

114 Many genes encoding acute phase proteins contain HNF-4alpha-binding sites in

115 t activation contributes to induction of the acute-phase proteins CRP and serum amyloid P-component (

116 ial expression of chemokines, cytokines, and acute-phase proteins, cytokeratin(+) epidermal cells upr

117 Serum acute-phase proteins, cytokines, and insulin-like growth

118 indicates that soluble CD14 in plasma is an acute-phase protein derived, among other sources, from l

119 with brief increase in body temperature and acute phase proteins during first infusion but no signs

120 abolites (e.g., propionate and isobutyrate), acute phase proteins (e.g., calprotectin and C-reactive

121 ells, elevated body temperatures and induced acute phase proteins, each indicative of infection, were

122 g and delivery of newly synthesized loads of acute-phase proteins, enhancing innate immunity and prev

123 y reduced levels of circulating and airspace acute-phase proteins, exhibited significantly elevated l

124 ck can significantly modulate the pattern of acute-phase protein expression and that fever may be an

125 a regulator of hepatocyte growth, and three acute phase protein family members.

126 atory process is facilitated by the negative acute-phase protein, fetuin.

127 tudies are needed to assess the potential of acute-phase proteins for inclusion in prediction models

128 rotein in hepatocytes resulting in a lack of acute phase protein gene induction in newborn C/EBPalpha

129 Northern blot analysis of acute-phase protein gene expression in neonatal mice tre

130 For acute phase protein genes, some were increased (TP53, JU

131 ntribute to the transcriptional induction of acute phase protein genes.

132 Unique for Dex was the upregulation of acute phase proteins (Gfap, Cp, Edn2) as well as Plexna2

133 glycan biomarker of N-acetyl side chains of acute-phase proteins (GlycA).

134 The human acute phase protein haptoglobin (Hp) protects the host f

135 major difference between Hpr and the soluble acute phase protein haptoglobin (Hp).

136 Recent evidence supports involvement of the acute phase protein haptoglobin in numerous events durin

137 Fibrinogen, an acute phase protein, has been shown to interact with the

138 ipheral measurement of circulating levels of acute phase proteins have focused attention on Clusterin

139 Elevations of acute-phase proteins have been associated with an increa

140 mation, including inflammatory cytokines and acute-phase proteins, have been found in depressed patie

141 n A deficiency in individuals with no raised acute-phase proteins (healthy group) were much the same

142 eripheral inflammatory markers including the acute phase protein high-sensitivity C-reactive protein

143 ver cells with characteristics resembling an acute-phase protein, human primary hepatocytes isolated

144 C-reactive protein (CRP), an acute phase protein in humans and rabbits, is part of th

145 P component or C-reactive protein, the major acute phase protein in humans, caused a decrease in the

146 C-reactive protein (CRP), the major acute phase protein in humans, was purified free of endo

147 Serum amyloid P component, the major acute phase protein in mice, increased from 27 microg/ml

148 rgy between dysregulated T-cell function and acute phase proteins in acute coronary syndromes.

149 tudies have shown that there is synthesis of acute phase proteins in enterocytes.

150 ME7 animals allow independent measurement of acute phase proteins in the brain and circulation, we ex

151 f p19 resulted in constitutive expression of acute phase proteins in the liver.

152 Because CRP, the most commonly used acute-phase protein in clinical practice, is very stable

153 C-reactive protein (CRP) is not an acute-phase protein in mice, and therefore, mice are wid

154 IL-1 receptor antagonist anakinra suppressed acute-phase proteins in a patient with FMF and amyloidos

155 re accompanied by rises in concentrations of acute-phase proteins in plasma.

156 ables, peak values of 15 cytokines, and nine acute-phase proteins in serum were evaluated as potentia

157 Here, we posit that inflammatory and acute-phase proteins in the circulation increase after O

158 oteins that are homologous to C-reactive and acute-phase proteins in the immune system and have been

159 at shock response could affect expression of acute-phase proteins in the liver, the effects of a mode

160 The upregulation of acute-phase proteins in the retina of diabetic rats was

161 Acute-phase proteins increased with treatment at all dos

162 Elevated circulating acute phase proteins indicate disease risk.

163 Acute phase proteins indicated no evidence of an inflamm

164 Elevated serum levels of acute-phase proteins, indicating chronic subclinical inf

165 to the endogenous Foxp3 locus, that IL-6, an acute phase protein induced during inflammation, complet

166 Serum amyloid A (SAA) is an acute-phase protein induced by a variety of inflammatory

167 ther increases in cytokine production and in acute phase protein-inducing ability in both patient gro

168 ared with FMF reflects greater production of acute phase protein-inducing cytokines in the former pat

169 could be due to differences in production of acute phase protein-inducing mediators, we studied PBMC

170 S and other microbial translocation markers, acute-phase proteins, inflammatory markers, and proinfla

171 e-rich alpha-2 glycoprotein (LRG) is a novel acute phase protein involved in inflammation-associated

172 Serum amyloid A (SAA) is a major acute phase protein involved in multiple physiological a

173 A major activity of acute phase proteins is to limit the inflammatory respon

174 rillation of Serum Amyloid A (SAA) - a major acute phase protein - is believed to play a role in the

175 active protein (CRP), the prototypical human acute phase protein, is an independent risk predictor of

176 Here, we show that haptoglobin, an acute phase protein, is an initiator of this MyD88-depen

177 YKL-40, a new acute-phase protein, is shown to be elevated in inflamma

178 ly characterised patient cohort revealed the acute phase protein lactoferrin (Lf) as the key predicto

179 kines CCL2, CXCL1 and IL-6 together with the acute phase protein Lcn2.

180 ortality, incidence of infection and sepsis, acute phase protein levels, and muscle fractional synthe

181 Acute-phase protein levels on HDL may serve as novel bio

182 ost significantly upregulated factors is the acute phase protein lipocalin-2 (LCN2).

183 This acute phase protein may have a role in the progression o

184 sclerosis since C-reactive protein (CRP), an acute-phase protein monitored as a marker of inflammator

185 In response to LPS, acute phase protein mRNA induction are equivalent in typ

186 C-reactive protein (CRP) is a plasma acute-phase protein, normally not found in the brain.

187 n C-reactive protein (CRP), a homopentameric acute-phase protein of the innate immune system, and a s

188 More than half of these ligands were acute phase proteins or members of the complement or coa

189 e towards understanding how inflammation and acute phase proteins, particularly serum amyloid A and g

190 y pathways including marked increases in the acute phase proteins pentraxin-3 and chitinase-3-like-1.

191 C-reactive protein (CRP) is an acute phase protein produced by hepatocytes.

192 C-reactive protein (CRP) is an acute-phase protein produced in high quantities by the l

193 ury, mortality, serum constitutive proteins, acute phase proteins, proinflammatory cytokines and insu

194 Fetuin, a negative acute-phase protein, recently was implicated as an anti-

195 C1-esterase inhibitor, an endogenous acute-phase protein, regulates various inflammatory and

196 ing a major modification of the mechanism of acute-phase protein regulation at 40 degreesC.

197 examined the association among elevations in acute phase proteins, reported illness, and hyporetinole

198 also reduced the lipopolysaccharide-induced acute phase protein response (C-reactive protein).

199 nergy, glucose, and lipid metabolism and the acute phase protein response; (3) the mechanisms by whic

200 ts is associated with induction of a hepatic acute-phase protein response and altered host energy and

201 higher in IL-6-/- mice (P < .05), while the acute-phase protein response was strongly attenuated (P

202 d by fever, anorexia, behavioral withdrawal, acute-phase protein responses, and inflammation.

203 We conclude that the acute phase protein SAA plays an important role in HDL c

204 the chemokines CXCL1, CXCL2, and S100A8; the acute-phase protein SAA3; and the LPS binding protein CD

205 ember of the serpin family (SERPINA3), is an acute-phase protein secreted by hepatocytes in response

206 ntified as a carboxy-terminal peptide of the acute phase protein serum amyloid A (SAA) 1.

207 The acute phase protein serum amyloid A (SAA) has been well

208 We have previously reported that the acute phase protein serum amyloid A (SAA) is a potent ch

209 Metabolic hormones, cytokines, and the acute phase protein serum amyloid a (SAA) were then meas

210 om the formation of amyloid fibrils from the acute phase protein serum amyloid A.

211 ing factor beta, inflammatory mediators, the acute phase protein serum amyloid P, vascular endothelia

212 The acute-phase protein serum amyloid A (A-SAA) was signific

213 The acute-phase protein serum amyloid A (SAA) is commonly co

214 The acute-phase protein serum amyloid A (SAA) is highly indu

215 e, all the six cytokines studied induced the acute-phase protein serum amyloid A when administered al

216 The endogenous acute-phase protein serum amyloid P (SAP) was expressed

217 HDL particles were enriched with acute-phase proteins (serum amyloid A, haptoglobin, and

218 showed comparable rises in the levels of two acute-phase proteins (serum amyloid P and C3) at 24, 48,

219 rkedly potentiated circulating levels of the acute phase proteins, serum amyloid A and IL-6, and the

220 ure supernatants and increased levels of the acute-phase protein, serum amyloid A (SAA).

221 ly are sensed by an evolutionarily conserved acute-phase protein, serum amyloid A1 (SAA1), that promo

222 Levels of several cytokines and acute-phase proteins significantly changed after treatme

223 oned medium increased mRNA levels of various acute-phase proteins such as albumin, fibrinogen, transf

224 In this context, acute-phase proteins such as Pentraxin-3 (PTX3) are rele

225 accompanied by a rapid rise in the blood of acute-phase proteins such as serum amyloid A (SAA).

226 Acute-phase proteins, such as C-reactive protein and alb

227 The detection of liver-derived acute-phase proteins suggests that BNB disruption facili

228 measuring cell proliferation or induction of acute phase protein synthesis.

229 terleukin-6 (IL-6) is the major regulator of acute-phase protein synthesis and one of the most studie

230 tuitary-adrenal axis and the potentiation of acute-phase protein synthesis.

231 Serum amyloid A (SAA) is a major acute-phase protein synthesized and secreted mainly by t

232 Hemopexin (Hx) is an acute-phase protein synthesized by hepatocytes in respon

233 sin (AAT) encoded by the SERPINA1 gene is an acute-phase protein synthesized in the liver and secrete

234 and C-reactive protein, which are two of the acute-phase proteins synthesized in response to infectio

235 ch less serum amyloid A and haptoglobin (two acute-phase proteins) than WT mice, there were no other

236 C-reactive protein (CRP) is an acute phase protein that binds phosphocholine residues o

237 Human C-reactive protein (CRP) is an acute phase protein that binds to receptors on human and

238 t secretory phospholipase A(2) (sPLA(2)), an acute phase protein that has been found in association w

239 Serum amyloid A is an acute phase protein that is carried in the plasma largel

240 A1AT is an acute phase protein that is expressed and secreted from

241 Alpha-1 antitrypsin (AAT) is an acute phase protein that possesses immune-regulatory and

242 Fibrinogen is an acute phase protein that will protect exposed cells from

243 d TNF-alpha followed by a decrease in type I acute phase proteins that was associated with a concomit

244 C-reactive protein (CRP) is an acute-phase protein that binds specifically to phosphory

245 uman C-reactive protein (CRP), the classical acute-phase protein that binds to ligands exposed in dam

246 ata suggest that shrimp LGBP is an inducible acute-phase protein that may play a critical role in shr

247 C-reactive protein (CRP) is an acute-phase protein that plays an important defensive ro

248 Pentraxins are acute-phase proteins that belong to a family of evolutio

249 WAT also secretes many cytokines and acute-phase proteins that contribute to insulin resistan

250 ar weight components (e.g., lipoproteins and acute phase proteins) that are closely associated with g

251 P) is well characterized as one of the serum acute phase proteins, the levels of which increase drama

252 rHGH decreased acute phase proteins, tumor necrosis factor-alpha, and I

253 ultiple chemokines, cell adhesion molecules, acute-phase proteins, type I IL-1 receptor, and multiple

254 er is the primary site for the production of acute phase proteins, typically serum amyloid A1 (SAA1)

255 Analyses were performed on cytokines, acute-phase proteins, virus load, and CD4 cell counts.

256 , hepatic mRNA of inflammatory cytokines and acute phase proteins was upregulated, and liver-infiltra

257 globulins and autoantibodies, cytokines, and acute-phase proteins were additional abnormalities, all

258 Levels of 13 cytokines and nine acute-phase proteins were measured using a bead-based mu

259 Many acute-phase proteins were up-regulated early in murine c

260 ent, genes related to cellular effectors and acute-phase proteins were up-regulated, whereas genes la

261 Serum amyloid A (SAA) is a family of acute-phase proteins which are shown to correlate with c

262 plasma proteomics analyses we observed that acute phase proteins - which are usually involved in the

263 ciated lipocalin (NGAL) is a 25-kDa secreted acute phase protein, which is also up-regulated in multi

264 Preoperative acute phase proteins (white cell count, C-reactive prote

265 Serum amyloid A (SAA) is an acute phase protein whose expression is markedly up-regu

266 Haptoglobin is an acute phase protein whose level increases severalfold du

267 C-reactive protein (CRP) is an acute phase protein whose levels are increased in many d

268 Fibrinogen is one of the acute-phase proteins whose levels are elevated during pe

269 Information about acute-phase proteins will enable plasma retinol concentr

270 C-reactive protein (CRP) is an acute-phase protein with a well-known association with i

271 Ceruloplasmin (Cp) is an acute-phase protein with ferroxidase, amine oxidase, and

272 C-reactive protein (CRP) is an acute-phase protein with therapeutic activity in mouse m