ライフサイエンスコーパス: acyclic

1 (the removal of vertices, leaving the graph acyclic).

2 cleavage of stable aromatic cyclic-fused and acyclic 1,2-diketones to deliver amides and imides in hi

3 ding olefin metathesis reactions that afford acyclic 1,2-disubstituted Z-alkenyl halides.

4 termolecular addition of aliphatic amines to acyclic 1,3-dienes.

5 Acyclic 1,4-diene products bearing either alkyl- or aryl

6 reaction and the Alder-ene reaction generate acyclic 1,4-dienes, which were investigated in the selen

7 in the biosynthesis of cholesterol) from the acyclic 2,3-oxidosqualene catalyzed by oxidosqualene cyc

8 owever, the addition of enolate derived from acyclic 2-oxo-butanoate 10 to 2H-azirine phosphine oxide

9 f an allenyl vinyl ketone was intercepted by acyclic, 2-silyloxy-substituted butadienes by highly reg

10 ituent to be grown to give the corresponding acyclic 7-chloro(bromo)-hepta-2,6-dienylmalonates.

11 he Au(I)-catalyzed cyclization of cyclic and acyclic acetals of alkynylaldehydes that leads to indeno

12 ently reported for catalytic alkynylation of acyclic acetals/ketals, and is uniquely enabled by the a

13 ious secondary alcohols including cyclic and acyclic alcohols and a wide variety of arylacetonitriles

14 ic ring-opening of O-heterocycles to provide acyclic alcohols and carboxylic acids with controlled fo

15 with a range of Grignard reagents to furnish acyclic alcohols with high diastereoselectivity.

16 e involving sequential alpha-alkynylation of acyclic aldehydes using hypervalent iodine reagents and

17 nt C-H bond iodination of various cyclic and acyclic alkanes providing iodoalkanes in good yields.

18 Diverse cyclic and acyclic alkenyl bromides or triflates with a wide range

19 -catalysed enantioselective Heck reaction of acyclic alkenyl fluorides with arylboronic acids.

20 cient processes that can be used to generate acyclic alkenyl halides.

21 the other hand, the modular approach led to acyclic alkyne-functionalized scaffolds of a controlled

22 ereocontrolled synthesis of tetrasubstituted acyclic all-carbon olefins has been developed via a ster

23 A variety of cyclic and acyclic allylic carbonates are competent electrophilic p

24 ytic methods used to access enantioenriched, acyclic alpha,alpha-disubstituted alpha-amino acids with

25 ies, such as propargyl or allyl groups, into acyclic alpha,beta,gamma,delta-doubly unsaturated accept

26 nd anti diastereomers of optically enriched, acyclic alpha,beta-disubstituted beta-aminoalkylboronate

27 enantioselective allylic substitutions with acyclic alpha-alkoxy ketones catalyzed by a metallacycli

28 ed copper(I) enolates generated in situ from acyclic alpha-alkoxy ketones.

29 ed arylation reaction of chiral, enantiopure acyclic alpha-amino aldehydes enabled by a B/Zn exchange

30 A direct, stereocontrolled synthesis of acyclic alpha-chloroenamides is presented.

31 The nature of the kinetic interaction of the acyclic alpha-CNPs against the herpetic DNA polymerases

32 ed asymmetric allylic alkylation (Pd-AAA) of acyclic alpha-hydroxyketones using boronic acids as trac

33 n) (pin=pinacolato) compounds to ketones and acyclic alpha-ketoesters was developed.

34 In contrast, other cyclic and acyclic alpha-oxoketenes lead preferentially to 1,3-oxaz

35 Acyclic alphagammaalpha-tripeptides derived from fluorin

36 yl-glutarimides to achieve full twist of the acyclic amide bond, and results in the discovery of N-ac

37 cale and could be performed with unprotected acyclic amide precursors.

38 Whereas acyclic amides are known to promote the hydroxylation of

39 and N-acyl-tosylamides (Ts), two classes of acyclic amides that have recently enabled the developmen

40 1, [((TMS) L)ClSi:-->Ni(NHC)2 ], bearing the acyclic amido-chlorosilylene ((TMS) L)ClSi: ((TMS) L=N(S

41 Facile oxygenation of the acyclic amido-chlorosilylene bis(N-heterocyclic carbene)

42 th heart failure generated a novel series of acyclic amine inhibitors displaying exceptional potency

43 Finally, the acyclic amines inactivated CYP3A4 and this liability was

44 action works successfully on both cyclic and acyclic amino ketone starting materials, as well as a ra

45 species under study belong to a subclass of acyclic aminoarylcarbenes.

46 the direct transamination of sugars to give acyclic aminopolyols.

47 d macrocycle was 60-fold more potent than an acyclic analog.

48 enhancement of up to 100-fold over flexible acyclic analogs was observed presumably due to an entrop

49 ncy of the cyclized compound relative to its acyclic analogue.

50 with the cyclophane reacting faster than its acyclic analogue.

51 (XB) bis-iodotriazole-pyridinium-containing acyclic and [2]catenane anion host systems are described

52 cules that comprise stereochemically complex acyclic and conformationally flexible carbon chains make

53 ons (X,Y = O,N) in the "alpha-systems" (both acyclic and constrained within a heterocyclohexane frame

54 )P-I(2) reagent system, the reaction of both acyclic and cyclic aliphatic tertiary amines led to the

55 d, internal alkenes, including those in both acyclic and cyclic alkenes, to afford chiral amines with

56 A range of acyclic and cyclic cis-olefins are suitable substrates,

57 onstrated by transforming them into valuable acyclic and cyclic compounds (including pharmacologicall

58 tioselective C-C bond-forming reactions with acyclic and cyclic enones, thereby converting these read

59 nient one-pot procedure for the synthesis of acyclic and cyclic guanidines mediated by the Ph3P/I2 sy

60 d and predictable assembly of complex chiral acyclic and cyclic nitrogen-containing motifs in one pot

61 ophores, the amino donors are varied between acyclic and cyclic while the alkoxy donors are varied in

62 hat allow the synthesis of a wide variety of acyclic and heterocyclic small molecules.

63 Ir-catalyzed hydroarylation of electron-rich acyclic and tensioned cyclic olefins with heterobiaryls

64 Stable acyclic arsenium cations R(2) As(+) , isoelectronic anal

65 is protocol is applicable to both cyclic and acyclic aryl ketones.

66 of the first synthetic nucleic acid with an acyclic backbone that can be transliterated to DNA by th

67 The preparation of acyclic beta-fluoro amines bearing tetrasubstituted fluo

68 cted trifluoromethyl aldimines and cyclic or acyclic beta-keto esters bearing different ester residue

69 ce) yielded five phenolic compounds, one new acyclic bis phenylpropanoid (1) and four previously know

70 bly, reaction of 1 with LiNH(2) leads to the acyclic bis(amido)silylene complex [(TMS)L(H(2)N)Si -> N

71 esis, metalation, and redox properties of an acyclic bis(iminothienyl)methene L(-) are presented.

72 Pioneering work revealed that acyclic boronic acids can act as 'transition state analo

73 ihydropyrans and 3,4-dehydropiperidines from acyclic building blocks in good yields without using any

74 lver-catalyzed hydroarylation of arynes from acyclic building blocks with unactivated arenes in intra

75 onship through the preparation of cyclic and acyclic C4-disubstituted analogs of 1, leading to the id

76 o-n-butadienes and flexible sigma-cyclic, pi-acyclic carbo-cyclohexadienes, and to "pro-aromatic" con

77 en considered, i.e. freely rotating sigma,pi-acyclic carbo-n-butadienes and flexible sigma-cyclic, pi

78 The preparation of acyclic, carbocyclic and azacyclic alpha-aminoboronic ac

79 ms the preferential reduction of cyclic over acyclic carbonate molecules, making its reduction produc

80 at is comparable to that of an unconstrained acyclic catalyst.

81 The naphthalene-walled acyclic CB[n] container is able to extract large hydroca

82 The acyclic CB[n]-type containers generally display signific

83 bles catalytic enantioselective formation of acyclic CF3-bearing all-carbon quaternary stereocenters

84 from the various propargyl aldehydes, cyclic/acyclic CH acids, and Hantzsch ester under ambient condi

85 he lithium dihydropnictides LiEH(2) with the acyclic chlorosilylene nickel(0) complex 1, [(TMS)L(Cl)S

86 ytic and diastereoselective isomerization of acyclic cinnamyl chlorides to strained cyclopropanes.

87 hydrogen-bonded molecular complex comprising acyclic components, namely, a stoppered thread (1) with

88 bohydrates, amino alcohols, and hydroxylated acyclic compounds in good to excellent yields.

89 nes, but also various other heterocycles and acyclic compounds through ring-opening and fragmentation

90 ws the construction of cyclic syn-ketols and acyclic compounds with multiple contiguous stereocenters

91 gram-scale synthesis of propargylated cyclic/acyclic compounds, and many of these coupling compounds

92 efficiently into a diverse set of cyclic and acyclic compounds, bearing up to four stereocenters.

93 lified ether series of inhibitors, utilizing acyclic conformational control to achieve proper amine p

94 ter cross-linking agents and cytotoxins than acyclic conjugates.

95 es made with the macrocyclic acceptor and an acyclic control molecule; we find that the superior perf

96 rocycle substructures were superior to their acyclic counterparts.

97 The ability of two water-soluble acyclic cucurbit[n]uril (CB[n]) type containers, whose h

98 olecular hosts (cyclodextrins, calixarenes, (acyclic) cucurbiturils, and pillararenes) as in vivo seq

99 ed for a homologous macrocyclic dimer and an acyclic derivative of pyromellitic diimide (PMDI).

100 cyclopropanes which can be transformed into acyclic derivatives bearing one or multiple tertiary or

101 a cyclic (alkyl)(amino)carbene (CAAC) and an acyclic diaminocarbene (ADAC), are able to undergo inser

102 Computed descriptors for acyclic diaminocarbene ligands are developed in the cont

103 merism in structurally simpler secondary and acyclic diarylamines.

104 employed as main-chain functional groups in acyclic diene metathesis (ADMET)-polymers, conferring du

105 oligomerization products (O) resulting from acyclic diene metathesis polymerization was increased fr

106 rgyl and 2-boryl-substituted allyl groups to acyclic dienoates with high selectivity.

107 clic carbene catalyzed cycloisomerization of acyclic dienyl esters to cyclohexyl beta-lactones.

108 oyed in the stereoselective synthesis of the acyclic dienyl moiety of the target molecule.

109 ted here is a simple method for synthesizing acyclic diketene acetal monomers from diols and vinyl et

110 s keto-esters or keto-sulfones and cyclic or acyclic diketones, afforded more than 30 2,3,5,6-tetrasu

111 Racemic acyclic diols as well as trans-cycloalkane-1,2-diols wer

112 trimerizations of 1,6-diynes with cyclic and acyclic double bonds.

113 provides direct entry to polyfunctionalized acyclic enamides, compounds of wide use in organic chemi

114 the enone products provides rapid access to acyclic enantiomerically enriched alpha,alpha'-dialkyl-s

115 The general approach to acyclic enediyne precursors fused to heterocycles includ

116 ained as single diastereomers from cyclic or acyclic enol ethers and styrenes.

117 lytic, asymmetric alpha-functionalization of acyclic esters constitutes a significant challenge in th

118 alytic asymmetric alpha-functionalization of acyclic esters.

119 ts is thermodynamically less stable than its acyclic ether isomer (O-CF(3)).

120 The direct alpha-arylation of cyclic and acyclic ethers with heteroarenes has been accomplished t

121 alpha-oxy C(sp(3))-H arylation of cyclic and acyclic ethers.

122 The methodology enables the formation of acyclic fluorine-containing compounds in good yields wit

123 drolytically interconvert between cyclic and acyclic forms, alone or in the presence of glycine under

124 The application of stereochemically defined acyclic fully substituted enolates of ketones to the ena

125 ng a set of sampled alignments as a directed acyclic graph (DAG) whose nodes are alignment columns; e

126 ctions, and they take the form of a directed acyclic graph (DAG).

127 Using a directed acyclic graph framework, we defined six causal scenarios

128 escribed by a tree but is instead a directed acyclic graph known as a phylogenetic network.

129 aph motifs, indicating recurrent wiring, and acyclic graph motifs, indicating feedforward wiring.

130 that extracts multiple overlapping directed acyclic graph structures from a raw sentence.

131 ormal theoretical causal framework (Directed Acyclic Graph).

132 random walks with restart on the GO directed acyclic graph, along with the available functions of a p

133 ic graphical model represented by a directed acyclic graph, which provides concise semantics to descr

134 nfounders that were identified in a directed acyclic graph.

135 si-Albert model, produces a growing directed acyclic graph.

136 arities were conceptualized using a directed acyclic graphic.

137 hical and connected organization as directed acyclic graphs (DAGs) and the lack of tools allowing to

138 Directed acyclic graphs (DAGs) are nonparametric graphical tools

139 the Markov equivalence class of the directed acyclic graphs (DAGs) in a genetical genomics analysis f

140 These models are represented as directed acyclic graphs (DAGs) of collections of 'selectivity' re

141 We used directed acyclic graphs and the example of bone lead and mortalit

142 In this paper, we use directed acyclic graphs to characterize potential biases in studi

143 We used directed acyclic graphs to examine healthy worker effects in stud

144 for generalizability and use causal directed acyclic graphs to show how these assumptions might play

145 Directed acyclic graphs were used to identify potential confounde

146 l inference methods (in particular, directed acyclic graphs), they describe different threats to the

147 o classes of models: 1) multi-level directed acyclic graphs, and 2) interdependent coupled networks.

148 as collider-stratification bias in directed acyclic graphs, but it is difficult to anticipate the ma

149 as can be guided using tools such as direct acyclic graphs.

150 ders were identified a priori using directed acyclic graphs.

151 nd an optimized doubly anthracene-terminated acyclic Hamilton-like receptor (2b), leads to an interlo

152 In MEGARes 2.0, the nodes of the acyclic hierarchical ontology include four antimicrobial

153 fashion and is demonstrated with cyclic and acyclic homoallylic and bishomoallylic alcohol substrate

154 llization, and solid state photochemistry of acyclic, homochiral, hexasubstituted (+)-(2R,4S)-2-carbo

155 ral sigma-hole halogen and chalcogen bonding acyclic hosts is demonstrated for the first time.

156 tations, showing that the seven-membered and acyclic hydrazide catalysts react 10 times faster than t

157 of gas-phase enthalpy of formation of cyclic/acyclic hydrocarbons and amines.

158 The [n]dendralenes are a family of acyclic hydrocarbons which, by virtue of their ability t

159 es of the plants, and recently characterized acyclic hydroxygeranyllinalool diterpene glycosides (HGL

160 Acyclic imines are unstable in aqueous conditions.

161 ydroxyacid dehydrogenase family that reduces acyclic imino acids produced in situ by a partner oxidas

162 Herein, we report a highly reactive acyclic iminosilylsilylene 1, which readily performs an

163 5 at the Michael acceptors with formation of acyclic intermediates, which subsequently cyclize to giv

164 ed utilizing synthetically inert unactivated acyclic internal olefins as allylic surrogates.

165 omoted by PhI(OAc)(2)/I(2), gives rise to an acyclic iodide through which a pentavalent atom of phosp

166 -cyclic products to <50% while increases the acyclic isomer selectivity to 38.6%.

167 se conversion of methylcyclopentane (MCP) to acyclic isomer, olefins, cyclohexane, and benzene.

168 each pair of which contains a cyclic and an acyclic isomer.

169 ne was the dominant product with olefins and acyclic isomers as minor products.

170 clohexane and benzene, respectively) without acyclic isomers products.

171 Acyclic ketone-derived oxocarbenium ions are involved as

172 erts control over asymmetric cyclizations of acyclic ketone-derived trisubstituted oxocarbenium ions,

173 Both cyclic and acyclic ketones can be mono-alpha-alkylated with simple

174 The asymmetric alkylation of acyclic ketones is a longstanding challenge in organic s

175 Enolizations of highly substituted acyclic ketones used in the syntheses of tetrasubstitute

176 for a variety of unsymmetrically substituted acyclic ketones.

177 is protocol is applicable to both cyclic and acyclic ketones.

178 An acyclic lead compound, containing an ether-linked isopro

179 The first group consisted of acyclic (linalool/linalyl acetate) chemotypes with a pre

180 and aza-silyl-Prins reactions, starting from acyclic materials, are reported.

181 e synthesis of many of the small yet complex acyclic members of this family.

182 ergoing facile one-electron oxidation to the acyclic, metal-free, neutral radical L(.) on reaction wi

183 Methyl as well as cyclic and acyclic methylene groups can be activated.

184 ides are capable of C-H functionalization in acyclic methylene groups in the absence of external liga

185 and modular protocol for the preparation of acyclic molecular frameworks containing newly created qu

186 various polyfunctionalized heterocycles and acyclic molecular scaffolds.

187 nt the missing link between nitrogen bearing acyclic molecules and prebiotic nucleobases along with v

188 igm shift for the synthesis of stereodefined acyclic molecules though selective carbon-carbon bond cl

189 To a greater extent than within acyclic molecules, these interactions within macrocycles

190 stereoselective assembly of amine-containing acyclic molecules.

191 e extent that halide recognition by a simple acyclic mono-charged receptor is achievable.

192 The acyclic monoterpene alcohol linalool is one of the most

193 as monoterpene synthases, forming cyclic and acyclic monoterpenes.

194 rect and rapid access to tetrahydropyrans in acyclic neopeltolide intermediates, a transannular strat

195 Meanwhile, a directed acyclic network of emerging phenomena is composed to mod

196 Our algorithm implements a directed acyclic network that reconstructs the complex behavioral

197 we report on the first examples of isolable acyclic, neutral, three-coordinate silanones 2 with inde

198 A long-term dream comes true: An acyclic, neutrally charged silanone at last!

199 ll the mechanistic gaps missing leading from acyclic nitrogen-bearing molecules via pyridine to NPAH-

200 vestigation of glycol nucleic acid (GNA), an acyclic nucleic acid analogue, as a modification of siRN

201 Acyclic nucleoside analogues used in this study were ide

202 Acyclic nucleoside bisphosphonates (ANbPs) have previous

203 ynthesized and evaluated several alkoxyalkyl acyclic nucleoside phosphonate diesters and identified o

204 Here, newly synthesized acyclic nucleoside phosphonates (ANPs) have been shown t

205 The aza-acyclic nucleoside phosphonates (aza-ANPs) are good inhi

206 the ProTide approach applied to a series of acyclic nucleosides aimed at the identification of novel

207 Acyclic nucleosides containing a 3-fluoro-2-(phosphonome

208 enation of unfunctionalized tetrasubstituted acyclic olefins remains the pinnacle of asymmetric synth

209 lecular [2+2] dimerization reaction of these acyclic olefins to construct cyclobutanes in a highly re

210 ow that hydroarylations occur with internal, acyclic olefins to yield linear alkylarene products.

211 eveloped to access a diversity of cyclic and acyclic oligosaccharide analogues designed as prefunctio

212 -oligomers were characterized to take either acyclic or cyclic molecular structures, depending on the

213 d successfully after assembling a variety of acyclic or cyclic monoketones with prenyl ether-tethered

214 ituted alkenyl-, 1,1-disubstituted alkenyl-, acyclic, or heterocyclic trisubstituted alkenyl groups m

215 While poly(acyclic orthoester)s (PAOEs) have many appealing feature

216 bond is exocyclic or the compound itself is acyclic, ozonolysis produces less ELVOC and the role of

217 rect but nonetheless widely held belief that acyclic pai-bond rich hydrocarbons are inherently unstab

218 These new acyclic pai-bond rich systems have extensive, untapped p

219 Ia inhibitors was designed based on our lead acyclic phenyl imidazole chemotype.

220 thetic orthogonal polymer embracing a chiral acyclic-phosphonate backbone [(S)-ZNA] is presented that

221 nal dispositions of their PMDI units and the acyclic PMDI derivative, we identified noticeable change

222 i) 1.60-1.95 and 2.37 V for oxidation of the acyclic PMDI derivative.

223 are linear equivalents of DNA with a neutral acyclic polyamide backbone that has nucleobases attached

224 actions provide new methods for synthesis of acyclic polyketide analogs with complex stereochemical a

225 lication to stereoselective synthesis of the acyclic portion of antifungal agent plakinic acid A, con

226 Cyclization of the acyclic precursor prepared on a solid phase using l-Ser

227 o bring together and fuse the two ends of an acyclic precursor such as an alkene (also known as an ol

228 A branched acyclic precursor was cyclized off-resin and then global

229 ultimately designed a highly functionalized acyclic precursor which underwent carefully orchestrated

230 of this hitherto elusive cyclic species from acyclic precursors in a single-collision event.

231 arin framework are constructed starting from acyclic precursors.

232 ularly substituted trans-fused decalins from acyclic precursors.

233 diastereoselectivity from readily available acyclic precursors.

234 cular Heck reaction of alkenyl triflates and acyclic primary or racemic secondary alkenols.

235 ic nickel-catalyzed ring-opening affords the acyclic product.

236 e inversion of configuration, to provide the acyclic products as a single diastereomer.

237 The optimized conditions afford the desired acyclic products embedding a methyl-aryl quaternary carb

238 allows for the generation of functionalized acyclic products from benzene.

239 In addition, cyclic and acyclic products generated during fatty acid metabolism

240 ng with olefins to construct both cyclic and acyclic products, respectively.

241 tioselective methods for the construction of acyclic quaternary carbon stereocenters from achiral or

242 ms have been documented, the construction of acyclic quaternary carbon stereocenters with control of

243 ovides a novel approach for the synthesis of acyclic quaternary carbon stereogenic centers and it rep

244 vides a new approach toward the synthesis of acyclic quaternary carbon stereogenic centers and provid

245 ed secondary alcohols 3a-3u that incorporate acyclic quaternary carbon-containing stereodiads.

246 y to prepare homoallylic alcohols containing acyclic quaternary centers is disclosed.

247 tally novel approach toward the synthesis of acyclic quaternary-substituted alpha,beta-unsaturated ke

248 on on C(1)-C(5) and C(1)-C(6) cyclization of acyclic quinoxalenediynes.

249 The XB acyclic receptor displays selectivity for acetate over h

250 pared to the analogous hydrogen-bonding (HB) acyclic receptor.

251 led interactions between substituents on the acyclic reference molecules.

252 -homodesmotic approach that minimizes use of acyclic references and ensures cancellation of intramole

253 hyl group in biasing the conformation in the acyclic region of the molecule.

254 Clinical studies suggest that the oral acyclic retinoid Peretinoin may reduce the recurrence of

255 e and seed oils are shown: triacylglycerols, acyclic saturated hydrocarbons, free sterols, and tocoph

256 l assays, we describe our efforts to develop acyclic scaffold-hops from GSK-690 (1).

257 Adding cycles to the acyclic scale-free graph increases cooperation when mult

258 otocol for efficient additions of cyclic and acyclic secondary alkyl amines to a wide range of alkyl

259 try of primary amines, as well as cyclic and acyclic secondary amines.

260 reactions of benzo[d]oxazol-2(3H)-ones with acyclic secondary amines.

261 e describe a systematic study of a series of acyclic secondary diarylamines, and we quantify the degr

262 Reactions of a boryl-substituted acyclic silylene with carbon dioxide and monoxide are re

263 rcise that provided additional insights into acyclic stereocontrol during stereochemically complex fr

264 Finally, the acyclic structure of 3(2-) prevents its use at neutral p

265 composition of metal clusters or the cyclic/acyclic structure of the reactants.

266 rrespective of alkane size (C2-C8) or cyclic/acyclic structure.

267 onal and structural diversity from a trivial acyclic substrate with no stereogenic centers.

268 tron-withdrawing group (EWG), present in the acyclic substrates with the mesyl leaving group, on the

269 ic centers in a single step from achiral and acyclic substrates.

270 ion of several new carbon-carbon bonds in an acyclic system and in a single-pot operation from simple

271 In an acyclic system, 1,3-trimethylsilyl migration successfull

272 finity for the enzyme when compared with the acyclic system.

273 stituted carbenes contrasts with that of the acyclic system.

274 sic conditions, qualifying these nonstrained acyclic systems as radical allylation reagents.

275 early fifty examples of propargylated cyclic/acyclic systems from the various propargyl aldehydes, cy

276 bond migration position, in both cyclic and acyclic systems, to furnish disubstituted and trisubstit

277 only just beginning to be realized in simple acyclic systems.

278 alpha-oxy sp(3) C-H bonds in both cyclic and acyclic systems.

279 ul approach to reveal sp(3) stereocenters in acyclic systems.

280 ion in heterocycles or synclinal geometry in acyclic systems.

281 tive process for the construction of vicinal acyclic ternary/ternary stereogenic centers, in addition

282 sources, including aromatic amino acids and acyclic terpenes, suggesting a reduction of metabolic fl

283 talyzed acylative kinetic resolution (KR) of acyclic tertiary alcohols has been developed.

284 eby allowing for the synthesis of cyclic and acyclic tetrasubstituted double bonds.

285 lation of alpha-nitro allyl esters to afford acyclic tetrasubstituted nitroalkanes.

286 been synthesized by SN2-like cyclizations of acyclic thioaminal precursors.

287 The acyclic thioaminals formed undergo intramolecular cycliz

288 The union of SnAP reagents and acyclic trifluoromethylketones yields alpha-CF3 morpholi

289 an efficient one-pot procedure that "folds" acyclic triketones into structurally complex, pharmaceut

290 e study that details the synthesis of stable acyclic trisubstituted [3]dendralenes and deciphers thei

291 ethods for the stereoselective generation of acyclic trisubstituted alkenes in either the E or the Z

292 Heck reaction between alkenyl triflates and acyclic trisubstituted alkenols of varying chain-lengths

293 n to the problem of ECA of alkenyl groups to acyclic trisubstituted enones, an advance achieved by ad

294 ligand has been used to stabilize the first acyclic two-coordinate dioxysilylene and its Ge, Sn, and

295 the first reported room temperature stable, acyclic, two-coordinate N,O-silylene 7 exhibiting a fasc

296 y contribute to antioxidant potential whilst acyclic unsaturated oxygenated monoterpenes (e.g. linalo

297 r aziridines are applied to the synthesis of acyclic versus cyclic products under catalyst-control ma

298 The reaction of acyclic vinyl ethers, dihydrofuran, and norbornenes with

299 in the XB [2]catenane, in comparison to the acyclic XB receptor, due to the interlocked host's uniqu

300 mical transformations that directly generate acyclic Z allylic alcohols, including products that cont