ライフサイエンスコーパス: adaptor protein 2

1 BRIa and BRII with a key component of CCPs, adaptor protein 2.

2 ed affinity of the aIIb subunit for clathrin adaptor protein 2.

3 heavy-chain) plaques and pits, expression of adaptor protein 2 (a clathrin adaptor protein), and epid

4 , which have reduced binding to the clathrin adaptor protein-2, a critical regulator of GABA(A)R endo

5 athrin-associated protein adaptor protein 1, adaptor protein 2 and adaptor protein 180 complexes from

6 periments indicate that LMBD1 interacts with adaptor protein-2 and is involved in the unique clathrin

7 mplexes and other endocytic proteins such as adaptor protein 2 (AP-2) and clathrin.

8 This led to the identification of adaptor protein 2 (AP-2) as a protein that recognizes th

9 We identified the mu2 subunit of adaptor protein 2 (AP-2) complex required for clathrin-m

10 Two of these proteins, a homolog of the adaptor protein 2 (AP-2) complex subunit alpha-1 and a h

11 pid down-regulation of CD4 via the endocytic adaptor protein 2 (AP-2) complex, a process linked to en

12 th the clathrin-associated, heterotetrameric adaptor protein 2 (AP-2) complex.

13 s internalized from the cell surface via the adaptor protein 2 (AP-2) complex.

14 binding to both phosphorylated receptors and adaptor protein 2 (AP-2) or clathrin, thus recruiting re

15 Inhibition of expression of the adaptor protein 2 (AP-2) or inhibition of clathrin by pi

16 ndocytosis, or by mutating putative clathrin adaptor protein 2 (AP-2) recognition motifs (Yxx ) in th

17 ion through canonical endocytic motifs in an adaptor protein 2 (AP-2)-dependent way.

18 requires palmitoylation for interacting with adaptor protein-2 (AP-2) and AP-3, respectively, for tra

19 n AAK1 phosphorylates the mu2 subunit of the ADAPTOR PROTEIN-2 (AP-2) complex (AP2M) and plays import

20 e clathrin endocytic machinery, clathrin and adaptor protein-2 (AP-2) in vitro.

21 Depletion of the mu subunits of either adaptor protein-2 (AP-2) or AP-1 using RNAi further prov

22 al cord slices and that it is carried out by adaptor protein-2 (AP-2) via clathrin-mediated endocytos

23 However, no loop-dependent binding of Nef to adaptor protein-2 (AP-2), which is the adaptor protein c

24 f Cell describes the atomic structure of the adaptor-protein 2 (AP-2) core, the portion that makes co

25 e phosphorylated active form of the clathrin adaptor protein 2 (AP2) at clathrin-coated pits.

26 , null mutations in subunits of the clathrin adaptor protein 2 (AP2) complex in Caenorhabditis elegan

27 identified as cargo proteins of the classic adaptor protein 2 (AP2) complex of the clathrin-mediated

28 ates low affinity binding with the endocytic adaptor protein 2 (AP2) complex.

29 It is well known that adaptor protein 2 (AP2) complexes trigger clathrin assem

30 Heterotetrameric adaptor protein 2 (AP2) complexes, which initiate clathr

31 Here we show that clathrin and adaptor protein 2 (AP2) were part of the LRP6 signalosom

32 Adaptor protein 2 (AP2), a heterotetrameric complex comp

33 he clathrin-scaffolding proteins B-arrestin, adaptor protein 2 (AP2), and dynamin.

34 ing RNA (siRNA), we found that inhibition of adaptor protein 2 (AP2), which mediates endocytosis of t

35 ds to the insulin receptor (IR) and prevents adaptor protein 2 (AP2)-mediated spontaneous IR endocyto

36 f predicted to recruit the clathrin adaptor, Adaptor protein 2 (AP2).

37 morphine-induced MOR endocytosis through an adaptor protein 2 (AP2)/clathrin-dependent mechanism, at

38 ation between the heterotetrametric clathrin adaptor protein-2 (AP2) and alpha-synuclein at presynaps

39 Adaptor protein-2 (AP2), a central component of clathrin

40 use gene knockouts led to the discovery that adaptor protein 2-associated kinase 1 (AAK1) is a potent

41 Adaptor protein 2-associated kinase 1 (AAK1) is a serine

42 reduced association with beta arr-2 and the adaptor protein-2 beta.

43 n 1 binding site and the other involving the adaptor protein 2 binding site.

44 re the ability of Nef to colocalize with the adaptor protein-2 complex (AP-2).

45 rlapping consensus motifs for binding to the adaptor protein-2 complex, and mutation of a tyrosine sh

46 with endothelium-specific deficiency of DAB adaptor protein 2 (Dab2) were subjected to measurement o

47 l interfering RNA against the mu2 subunit of adaptor protein 2, dominant negative dynamin construct K

48 ere clathrin interacts with the membrane via adaptor proteins; 2) elongation, where the membrane is t

49 Now, two studies agree that four-phosphate adaptor protein 2 (FAPP2) transfers glucosylceramide (Gl

50 targeting the PI4P effector, four-phosphate adaptor protein 2 (FAPP2).

51 This motif binds adaptor protein-2 in glutathione S-transferase-uncoverin

52 eimide-sensitive fusion protein-AP2-clathrin adaptor protein 2 inhibitory peptide pep2m occluded LTD

53 , a motif that interacts with mu2 subunit of adaptor protein 2, is critical for the cell motility-pro

54 morphisms rs3769502 and rs7573751 in the NCK adaptor protein 2 (NCK2) gene positively associated with

55 The adaptor protein-2 sigma subunit (AP2sigma2) is pivotal f

56 this receptor is dependent on the binding of adaptor protein 2 to the specific LLKIL motif found with

57 iated endocytosis, as well as association of adaptor protein-2 with clathrin-coated pits.