ライフサイエンスコーパス: adenylyltransferase

1 o covalent modification (adenylylation by GS adenylyltransferase).

2 s a nicotinic acid mononucleotide-preferring adenylyltransferase.

3 es of Fic proteins with those of other known adenylyltransferases.

4 ors is carried out by MccB THIF-type NAD/FAD adenylyltransferases.

5 rase (NAMPT) and nicotinamide mononucleotide adenylyltransferase 1 (NMNAT-1) constitute a nuclear NAD

6 The nicotinamide nucleotide adenylyltransferase 1 (NMNAT1) enzyme is essential for r

7 Nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1) is required for nuclear n

8 (GAD), by the enzyme nicotinamide nucleotide adenylyltransferase 1 (NMNAT1) of the NAD(+) salvage pat

9 verexpression of nicotinamide mononucleotide adenylyltransferase 1 (Nmnat1) or exogenous application

10 Nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1), a nicotinamide adenine d

11 ding sequence of nicotinamide mononucleotide adenylyltransferase 1 (Nmnat1), which alone is sufficien

12 biosynthetic enzyme nicotinamide nucleotide adenylyltransferase 1 (NMNAT1).

13 ed redistribution of nicotinamide nucleotide adenylyltransferase 1 from nuclei to axons in primary ne

14 NAD(+) synthase nicotinamide mononucleotide adenylyltransferase-1 (NMNAT1) in the developing murine

15 Nicotinamide mononucleotide (NMN) adenylyltransferase 2 (Nmnat2) catalyzes the synthesis o

16 thesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) is a critical survival fa

17 Nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) is an endogenous axon mai

18 Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) plays an important role i

19 evels of NMNAT2 (nicotinamide mononucleotide adenylyltransferase 2), a recently identified survival f

20 clear isoform of nicotinamide mononucleotide adenylyltransferase, a rate-limiting enzyme in nicotinam

21 by LigB, thus confirming that the ligase and adenylyltransferase activities are intrinsic to the LigB

22 bose at position -3 markedly stimulates both adenylyltransferase activity and stable binding.

23 igase is thermophilic in vitro, with optimal adenylyltransferase activity at 90 degrees C and nick-jo

24 untingtin yeast interacting protein E), with adenylyltransferase activity but unknown physiological t

25 rate that the PfhB2 Fic domains also possess adenylyltransferase activity that targets the switch 1 t

26 verexpression of GS in glnE mutants (lacking adenylyltransferase activity) also causes poor growth.

27 the primer is absolutely required for VP55's adenylyltransferase activity, but not for stable VP55-RN

28 ereas LigC and LigD, which have ATP-specific adenylyltransferase activity, display weak nick joining

29 her yeast NMNATs, Pof1 exhibits NMN-specific adenylyltransferase activity.

30 lylation (inactivation) by a bifunctional GS adenylyltransferase/adenylyl-removing enzyme (ATase).

31 ggesting that GlnK-UMP is required to signal adenylyltransferase/adenylyl-removing enzyme-mediated de

32 pyrophosphorylase (AGP; glucose-1-phosphate adenylyltransferase; ADP: alpha-D-glucose-1-phosphate ad

33 ucose pyrophosphorylase (glucose-1-phosphate adenylyltransferase; ADP:alpha-D-glucose-1-phosphate ade

34 (ybeN) coding for nicotinate mononucleotide adenylyltransferase, an NAD(P) biosynthetic enzyme, has

35 LnaB harbors both adenylyltransferase and ATPase activities, which reveal

36 tA antitoxin (MNT-domain protein) acts as an adenylyltransferase and chemically modifies the HepT tox

37 Adenylyltransferase and DNA ligation activities are pres

38 ses characterized to date have ATP-dependent adenylyltransferase and nick-joining activities.

39 ridylyltransferase/uridylyl-removing enzyme, adenylyltransferase, and the kinase/phosphatase nitrogen

40 , and the C-terminal NT domain contained the adenylyltransferase (AT) active site.

41 In vivo, adenylyltransferase (AT) activity is critical for growth

42 The adenylyltransferase (AT) activity of ATase is activated

43 toglutarate and ADP on PII activation of the adenylyltransferase (AT) activity of ATase.

44 The adenylyltransferase (AT) reaction is activated by glutam

45 enzyme nicotinic acid mononucleotide (NaMN) adenylyltransferase (AT), is essential for the synthesis

46 es of the PII receptors glutamine synthetase adenylyltransferase (ATase) and the kinase/phosphatase n

47 ntrol the activities of glutamine synthetase adenylyltransferase (ATase) but did not affect the abili

48 Glutamine synthetase adenylyltransferase (ATase) regulates the activity of gl

49 II (NRII) and the glutamine synthetase (GS) adenylyltransferase (ATase), and is subject to reversibl

50 ate in a reconstituted system containing GS, adenylyltransferase (ATase), the PII signal transduction

51 Both GlnK and PII also acted through adenylyltransferase (ATase, the glnE product) to regulat

52 biosynthetic enzymes, including a ThiF-like adenylyltransferase/cyclase that generates a C-terminal

53 A new family of adenylyltransferases, defined by the presence of a Fic d

54 recombinant bifunctional phosphopantetheine adenylyltransferase/dephospho-CoA kinase was kinetically

55 We identify five amino acids in the adenylyltransferase domain (Lys114, Glu266, Gly267, Lys2

56 k depends on contacts to both the N-terminal adenylyltransferase domain and its signature C-terminal

57 no acid polypeptide composed of a C-terminal adenylyltransferase domain fused to a distinctive 126 am

58 stinctive structure composed of a C-terminal adenylyltransferase domain linked to an N-terminal modul

59 Trl1 consists of an N-terminal adenylyltransferase domain that resembles T4 RNA ligase

60 a sudden (NH4)+ upshift, strains lacking GS adenylyltransferase drain their glutamate pool into glut

61 eine decarboxylase (EC ), phosphopantetheine adenylyltransferase (EC ), and dephospho-CoA kinase (EC

62 transferase; ADP:alpha-D-glucose-1-phosphate adenylyltransferase, EC 2.7.7.27) catalyzes a key regula

63 ransferase; ADP: alpha-D-glucose-1-phosphate adenylyltransferase, EC 2.7.7.27), a key starch biosynth

64 Bacterial nicotinate mononucleotide adenylyltransferase encoded by the essential gene nadD p

65 tabolite of WldS/nicotinamide mononucleotide adenylyltransferase enzymatic activity, is sufficient an

66 n by both NMNAT (nicotinamide mononucleotide adenylyltransferase) expression and loss of wallenda/DLK

67 et another member of the pyridine nucleotide adenylyltransferase family.

68 Flavin mononucleotide adenylyltransferase (FMNAT) catalyzes the formation of t

69 s the RFK activity, while the N-terminal FMN-adenylyltransferase (FMNAT) exhibits the FMNAT activity.

70 he core dinucleotide-binding fold with other adenylyltransferases from bacteria to human despite a li

71 These enzymes, NaMN adenylyltransferase (gene nadD) and NAD synthetase (gene

72 or is controlled post-translationally by the adenylyltransferase (GlnE) as in enteric bacteria.

73 utagenic exploration of the PPi motif in any adenylyltransferase is that the residues of the motif pa

74 dentify inhibitors of Mtb phosphopantetheine adenylyltransferase (MtbPPAT), the enzyme that catalyses

75 Nicotinate mononucleotide adenylyltransferase NadD is an essential enzyme in the b

76 nstream enzymes of NAD synthesis, nicotinate adenylyltransferase (NadD family) and NAD synthetase (Na

77 of NAD biogenesis, nicotinate mononucleotide adenylyltransferase (NadD) and NAD synthetase (NadE), ar

78 lase subunit, probable nicotinate-nucleotide adenylyltransferase, NADH-quinone oxidoreductase, holo-[

79 Bacterial nicotinic acid mononucleotide adenylyltransferase (NaMNAT; EC 2.7.7.18) encoded by the

80 on is catalyzed by nicotinate mononucleotide adenylyltransferase (NMAT), which is essential for bacte

81 The central domain has a weak adenylyltransferase (NMN-AT; EC 2.7.7.1) activity that c

82 f nicotinamide/nicotinic acid mononucleotide adenylyltransferase (NMNAT) act as a powerful suppressor

83 of NAD synthase nicotinamide mononucleotide adenylyltransferase (NMNAT) against activity-induced neu

84 , constituted by nicotinamide mononucleotide adenylyltransferase (NMNAT) and nicotinamide phosphoribo

85 , (ii) a central nicotinamide mononucleotide adenylyltransferase (NMNAT) domain, and (iii) a C-termin

86 synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT) have uncovered a novel neuro

87 Nicotinamide mononucleotide adenylyltransferase (NMNAT) is a conserved enzyme in the

88 inamide/nicotinate mononucleotide (NMN/ NaMN)adenylyltransferase (NMNAT) is an indispensable enzyme i

89 th a decrease in nicotinamide mononucleotide adenylyltransferase (Nmnat) protein levels.

90 verexpression of nicotinamide mononucleotide adenylyltransferase (Nmnat), a component of the slow Wal

91 Importantly, nicotinamide mononucleotide adenylyltransferase (NMNAT), an evolutionarily conserved

92 d nicotinamide/nicotinic acid mononucleotide adenylyltransferase (Nmnat), and we examined its effects

93 it is a putative nicotinamide mononucleotide adenylyltransferase (NMNAT).

94 on of Wld(S) and nicotinamide mononucleotide adenylyltransferase (Nmnat).

95 cal to the human nicotinamide mononucleotide adenylyltransferase (NMNAT).

96 synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) is frequently deleted in hu

97 ynthetic enzyme, nicotinamide mononucleotide adenylyltransferase (Nmnat1).

98 s is mediated by nicotinamide mononucleotide adenylyltransferases (NMNATs), but their role in Parkins

99 cipate; we discuss scenarios in which the 5'-adenylyltransferase of RtcA might play a role.

100 The second step is performed by NMN adenylyltransferase of the NadM family.

101 ferring enzymes such as glutamine synthetase adenylyltransferase or kanamycin nucleotidyltransferase,

102 pathways, including three distantly related adenylyltransferases (orthologs of the E. coli genes nad

103 Pyridine nucleotide adenylyltransferase (PNAT) is an indispensable central e

104 Phosphopantetheine adenylyltransferase (PPAT) catalyzes the penultimate ste

105 Phosphopantetheine adenylyltransferase (PPAT) catalyzes the penultimate ste

106 Phosphopantetheine adenylyltransferase (PPAT) from Escherichia coli is an e

107 method was applied to 4'-phosphopantetheine adenylyltransferase (PPAT) from Mycobacterium abscessus

108 Phosphopantetheine adenylyltransferase (PPAT) is an essential enzyme in bac

109 Phosphopantetheine adenylyltransferase (PPAT) is an essential enzyme in the

110 Phosphopantetheine adenylyltransferase (PPAT) regulates the key penultimate

111 Each phosphopantetheine adenylyltransferase (PPAT) subunit displays a dinucleoti

112 e base substitution in Dde_2265, the sulfate adenylyltransferase (sat).

113 nicotinamide mononucleotide (NMN)-preferring adenylyltransferase (slr0787 gene).

114 Enzyme assays showed that one of the adenylyltransferases specifically recognizes aspartic ac

115 , the S. aureus NaMNAT represents a distinct adenylyltransferase subfamily identifiable in part by co

116 termined that Delta97nsP4 possesses terminal adenylyltransferase (TATase) activity, as it specificall

117 tein has metal ion-dependent RNA 3'-terminal adenylyltransferase (TATase) activity, while other nucle

118 in putative sulfate permease and not sulfate adenylyltransferase transcripts, suggesting a role for f

119 nd compare its activity with other known Fic adenylyltransferases, VopS (Vibrio outer protein S) from

120 sed biosynthetic pathway, two genes encoding adenylyltransferases were overexpressed and the resultin

121 Unlike other bacterial adenylyltransferases, where a partially conserved histid