ライフサイエンスコーパス: adhesin

1 dels for the regulation and function of this adhesin.

2 l upstream domain of a Staphylococcus aureus adhesin.

3 teolytic cleavage to act as an intercellular adhesin.

4 dence for a CBM40 as a novel bacterial mucus adhesin.

5 ting a domain from a Gram-positive bacterial adhesin.

6 ordonii modifies the Ser/Thr-rich repeats of adhesin.

7 s GtfB provides the primary binding site for adhesin.

8 capacitor coated with T4 bacteriophage gp37 adhesin.

9 icating that OspA may serve as a tick midgut adhesin.

10 s (LPG) coated with T4 bacteriophage (phage) adhesin.

11 ctivity of its type IV pili, a major surface adhesin.

12 tural arrangements, including a fimbrial tip adhesin.

13 d stress and elevated expression of fimbrial adhesins.

14 which NTHI binds via engagement of multiple adhesins.

15 serine-rich repeat protein (SRRP) family of adhesins.

16 glycan binding of human pathogen lectins and adhesins.

17 factor CS23 but is negative for other known adhesins.

18 exhibit the characteristics of multispecific adhesins.

19 stis in its hosts, in conjunction with other adhesins.

20 que and define a new class of polysaccharide adhesins.

21 iarrhea, colonizes the intestine by means of adhesins.

22 that involve microbial surface proteins, or adhesins.

23 observed in structures of other Siglec-like adhesins.

24 on the bacterial-centric mechanisms such as adhesins.

25 asses the design of agonists targeting these adhesins.

26 nserved arginines, are shared by the class 5 adhesins.

27 icobacter pylori blood group antigen binding adhesin A (BabA) is more common in strains isolated from

28 um bromide in combination with the Neisseria adhesin A variant 3 subunit antigen.

29 ence strain (5/99, which included neisserial adhesin A), both of which were used in vaccine developme

30 onent plus 3 recombinant antigens (Neisseria adhesin A, factor H binding protein [fHbp]-GNA2091, and

31 The binding domains of A. phagocytophilum adhesins A. phagocytophilum invasion protein A (AipA), A

32 entify the fusobacterial galactose-sensitive adhesin, a system for transposon mutagenesis in fusobact

33 nique gene locus encoding an amylase-binding adhesin AbpA and a sortase B in oral streptococci.

34 forms a channel for translocation of the Hsa adhesin across the cytoplasmic membrane.

35 that the exoprotein possesses an additional adhesin activity.

36 identify how the S. sanguinis strain SK1 SRR adhesin affects interactions with sialylated glycans and

37 d its characteristic fimH64 (type 1 fimbrial adhesin) allele.

38 expression for the major fungal cell surface adhesin Als3 and the aspartic proteases Sap6 and Sap9.

39 me suggested also an involvement of the Mp65 adhesin and a "moonlighting" protein, enolase, as partne

40 e components: the pathogenic agent, a lectin/adhesin and a glycan ligand.

41 AmOmpA is both an adhesin and an invasin, as coating inert beads with it c

42 us assembly and traffic the pilus-associated adhesin and anti-retraction protein, PilY1, to the cell

43 s engineered from a Streptococcus pneumoniae adhesin and enables isopeptide bond formation between tw

44 throcyte cytoskeleton and trafficking of the adhesin and key virulence factor PfEMP1 to the host cell

45 colonization factors comprising a minor tip adhesin and major stalk-forming subunit.

46 lacking expression of pertactin, a bacterial adhesin and vaccine target, are emerging.

47 reviously shown binds to ICAM1, an essential adhesin and virulence determinant, we next showed that T

48 ofuranose-containing polysaccharides conceal adhesins and are important for membrane integrity.

49 n of OM-NPs avoids the identification of the adhesins and bypasses the design of agonists targeting t

50 e adaptations include expression of specific adhesins and cell wall re-modeling to attach to the root

51 l cells, the bacterium produces a variety of adhesins and delivers virulence factors.

52 ne exposure, these cells overproduce the Prg adhesins and display impaired envelope integrity, as evi

53 anisms to colonize host cells, as nearly all adhesins and effectors involved in host cell entry are d

54 mportant for stabilizing motility-associated adhesins and for host infection in other apicomplexan pa

55 is governed by interactions between parasite adhesins and red blood cell receptors.

56 and fitness factors but do have a variety of adhesins and regulatory pathways.

57 overproduction, block production of the Prg adhesins and render cells insensitive to pheromone.

58 ad amino acid sequence homology to bacterial adhesins and structural homology to bacterial lysozyme i

59 tween the cytoplasmic tails of transmembrane adhesins and the actin-myosin motor.

60 nderstand functional epitopes of the class 5 adhesins and their ability to induce intraclass antibody

61 gulation of principal virulence factors (eg, adhesins and toxins) and biofilm formation.

62 vB and PspC are pneumococcal surface-exposed adhesins and virulence factors exhibiting repetitive seq

63 contained allele 41 of fimH (type 1 fimbrial adhesin) and a narrow range of alleles of gyrA and parC

64 stile interactions (i.e. hemolysins, pilins, adhesins), and exoenzymes with a potential mixotrophic g

65 of VanZ and a SrtB-anchored collagen-binding adhesin, and correspondingly, all tested RT106 strains h

66 ls to whole bacterial lysate, recombinant P1 adhesin, and OVA.

67 us haemagglutinin (FHA), a surface-displayed adhesin, and until now, the consequences of this interac

68 dorferi s. l. bacteria, recombinant borrelia adhesins, and an array of adhesion assays carried out bo

69 ted loci that include genes encoding toxins, adhesins, and other cell surface proteins, and over 200

70 site effector proteins, including perforins, adhesins, and proteases, are extensively proteolytically

71 on requires two enzymes: LapG, which cleaves adhesins, and RbmB, which digests matrix polysaccharides

72 Here, we followed the adhesin Apa-specific T-cell responses in BCG-primed mice

73 cytoplasmic domain of the essential invasion adhesin apical membrane antigen 1 (AMA1) regulates eryth

74 Outer-surface adhesins are crucial in the bacterial dissemination and

75 To date, adhesins are only known to bind to host receptors non-co

76 rpA, similar in sequence to platelet-binding adhesins associated with increased virulence in this dis

77 cells is mediated by FimH, a mannose-binding adhesin at the tip of bacterial type 1 pili.

78 This attachment is facilitated by bacterial adhesins at the cell surface.

79 The Helicobacter pylori adhesin BabA binds mucosal ABO/Le(b) blood group (bg) ca

80 ructural analyses of the Helicobacter pylori adhesin BabA to determine how the bacteria discriminatel

81 The results imply that multivalent adhesin-based ETEC vaccines or prophylactics need more t

82 also revealed unexpected roles for Borrelia adhesins BBK32 and OspC in bacterial burdens in the bloo

83 ersinia ruckeri produces two surface-exposed adhesins, belonging to the inverse autotransporters (IAT

84 mental data of the filamentous hemagglutinin adhesin beta-barrel protein transporter solubilized by n

85 and an ALD mutant that specifically disrupts adhesin binding in vitro also supported normal invasion

86 We show that T4 phage adhesin binds E. coli B LPS in its native or denatured f

87 The adhesin binds Escherichia coli B (E. coli B) by precise

88 ation of highly conserved serine-rich repeat adhesins by a series of glycosyltransferases.

89 ation requires proper positioning of the tip adhesin CafA via modulation of pilus length by the house

90 utant led to the discovery that the putative adhesin CD0386 is anchored to the peptidoglycan of C. di

91 two sortase-anchored proteins, the putative adhesins CD2831 and CD3246, and determine the cell wall

92 ility of the donor strand-complemented CFA/I adhesin CfaE (dscCfaE) to protect against H10407 challen

93 noclonal antibodies (MAbs) to representative adhesins CfaE, CsbD, and CotD, respectively.

94 f heart tissue is dependent on the bacterial adhesin choline-binding protein A that binds to laminin

95 e major pilus backbone subunit (RrgB) or the adhesin component (RrgA) impaired pneumococcal associati

96 The C-terminal part of the adhesin consists of the receptor-binding amino acid resi

97 The surface-localized S. mutans P1 adhesin contributes to tooth colonization and caries for

98 The fibrillar adhesin CshA is an important determinant of S. gordonii

99 The multifunctional fibrillar adhesin CshA, which mediates binding to both host molecu

100 Two well-characterized Borrelia adhesins, decorin-binding proteins A and B, have been sh

101 We also evaluated how adhesin-deficient H pylori strains, chemical competition

102 n experiments with other pneumococcal hTSP-1 adhesins demonstrated that PspC and PspC-like Hic recogn

103 Adhesin domain immunization also elicited interferon gam

104 ing pocket abrogates the binding of the SabA adhesin domain to sialyl-Lewis(X) and Lewis(X).

105 ic Gram-negative Pseudomonas aeruginosa uses adhesins (e.g., LecA and LecB lectins, type VI pili and

106 These genes included cell wall-anchored adhesins (ebh, sdrD), polysaccharide and capsule synthes

107 elial tissue, facilitated by the C. albicans adhesin encoded by ALS3 While a bacterium-fungus interac

108 . albicans and radD, an arginine-inhibitable adhesin-encoding gene in F. nucleatum that is involved i

109 o competition in gnotobiotic mice include an adhesin enriched in poor colonizers.

110 ted the fungal ligands to be the C. glabrata adhesins Epa1, Epa6, and Epa7 and demonstrated that clea

111 f more than 20 cell wall-attached epithelial adhesins (Epas).

112 ll wall proteins, the lectin-like epithelial adhesins (Epas).

113 es utilizes the protein Cpa, a pilus tip-end adhesin equipped with a Cys-Gln thioester bond.

114 llular receptors or bacterial outer membrane adhesins essential for this process are unknown.

115 we identify the HopQ protein as a genuine Hp adhesin, exploiting defined members of the carcinoembryo

116 udies advance our knowledge of regulation of adhesin expression associated with uropathogen colonizat

117 In staphylococci, the adhesins extracellular adherence protein (Eap) and autol

118 cleatum clinical isolates with FadA and Fap2 adhesins failed to induce inflammation and tumorigenesis

119 The adhesin family of polymorphic membrane proteins (Pmp) in

120 T116 CRC cells through the bacterial surface adhesin Fap2.

121 For example, the type 1 pilus adhesin FimH binds mannose on the bladder surface, and m

122 terize the interactions between the fimbrial adhesin FimH from uropathogenic Escherichia coli strains

123 Here we study the bacterial adhesin FimH to address the role of the inactive conform

124 One example is the bacterial adhesin FimH, where the C-terminal pilin domain exerts n

125 nd FimH antagonists that block the bacterial adhesin FimH, which would otherwise mediate binding of u

126 antivirulence inhibitors of the type 1 pilus adhesin, FimH, demonstrated oral activity in animal mode

127 olved in bacterial virulence such as toxins, adhesins, flagella, and pili, among others.

128 The Fml adhesin FmlH binds galactose beta1-3 N-acetylgalactosami

129 man phagocytes and mice, whereas the surface adhesin FnbA contributes to the increased bacterial burd

130 YapV acted as an adhesin for alveolar epithelial cells and specific extra

131 ilitated by the exquisite selectivity of the adhesins for their cognate ligands or receptors and is a

132 The SRR adhesin from Streptococcus sanguinis strain SK1 has tand

133 However, SadP adhesin from systemic subtype P(N) strains also binds to

134 nd Random Forest analyses of known/suspected adhesins from 580 independent Typhimurium isolates ident

135 estigate the role of Flo11-type cell surface adhesins from social yeasts in kin discrimination.

136 he first clinical evidence that fimbrial tip adhesins function as protective antigens.

137 Hindering iron uptake and disrupting adhesins' function could be a relevant antipseudomonal s

138 alters expression of epithelial barrier and adhesin genes, which, in turn, promotes Staphylococcus a

139 The adhesin (gp37) binds Escherichia coli B (E. coli B) by r

140 The specificity of LPS binding by adhesin has been tested with LPG-based device and confir

141 lactose and the first time that one of these adhesins has been shown to be required for binding of mu

142 The F9/Yde/Fml pilus, tipped with the FmlH adhesin, has been shown to provide uropathogenic Escheri

143 onal classification and explain how Epa-like adhesins have evolved in C. glabrata and related fungal

144 tudies on a class of Gram-positive bacterial adhesins have revealed an intramolecular Cys-Gln thioest

145 ociated nsSNPs for FimH, the type 1 fimbrial adhesin, highlights the role of key allelic residues in

146 ed protein domain, based on the cell-surface adhesin HMW1A, is preferentially recognized by antibodie

147 lly infectious strains uniformly express Opa adhesins; however, their specificities were unknown at t

148 lysin/cytolysin (beta-h/c), surface-anchored adhesin HvgA, and capsule to study the role of CovR in U

149 ed protease, Sap6, and a hyphal cell surface adhesin, Hyr1.

150 ollagenous structures and may function as an adhesin in a process that is required to prevent bacteri

151 The major surface adhesin in HCG is called Cha, which mediates bacterial a

152 ity accompanying overproduction of PrgB-like adhesins in E. faecalis and other clinically-important G

153 The MAbs' reactivities to a panel of class 5 adhesins in enzyme-linked immunosorbent assays (ELISAs)

154 A range of fimbrial adhesins in ETEC strains determines host and tissue trop

155 efine the biological roles of B. burgdorferi adhesins in tissue-specific vascular interactions.

156 These adhesins include integrin alphabeta heterodimers in meta

157 mophilus influenzae, expressing cell-surface adhesins including N-Glc, to establish a connection betw

158 reus expresses a panel of cell wall-anchored adhesins, including proteins belonging to the microbial

159 etion of srr1, encoding a fibrinogen-binding adhesin, increases GBS survival in whole blood.

160 We show that Pla functions as an adhesin independent of its proteolytic function to suppr

161 s of entry into host tissue, wherein surface adhesins interact with the extracellular matrix, enablin

162 The MAM(HS) adhesin interacted with a range of host receptors, throu

163 The arsenal of pneumococcal adhesins interacts with a multitude of extracellular mat

164 nt (LEE) pathogenicity island, including the adhesin Intimin and T3SS filament EspA, which are major

165 ernalization is interaction of the bacterial adhesins invasin and YadA with host cell beta1 integrin,

166 ins in the cell membrane, whereas the mature adhesin is incorporated into the cell wall.

167 3 and provide evidence that this lipoprotein adhesin is part of a tyrosine import system, an amino ac

168 In conclusion the hyperglucosylated adhesin is the first example of an N-glucosylated native

169 One such UPEC adhesin is the nonfimbrial adhesin TosA, which mediates

170 a stabilized form of the CFA/I fimbrial tip adhesin, is a protective antigen, using a lethal neonata

171 rominent function in the regulation of other adhesins, is also hypothesized to contribute to tos oper

172 ification of a yet uncharacterized bacterial adhesin, LabA, which specifically recognizes lacdiNAc.

173 in LapD, and resulting in proteolysis of the adhesin LapA and the subsequent release of biofilm cells

174 escens occurs through the localization of an adhesin, LapA, to the outer membrane via a variant of th

175 hough V. fischeri encodes two putative large adhesins, LapI (near lapG on chromosome II) and LapV (on

176 hat promotes cleavage of a biofilm-promoting adhesin, LapV.

177 Here, we investigated the potential role of adhesin-like autotransporter proteins in S. flexneri bio

178 nes, S1242, S1289, S2406, and icsA, encoding adhesin-like autotransporter proteins.

179 we identified FLO9, which encodes a putative adhesin-like cell wall mannoprotein of C. albicans and r

180 olled by modifications of the stage-specific adhesin lipophosphoglycan (LPG).

181 -peps produced from a model LPXTG-containing adhesin localized to the cell membrane and bound to and

182 Of these the 21 kDa Leptospira surface adhesin, Lsa21 had strong TLR2 and TLR4 activity leading

183 of clinical isolates are negative for known adhesins, making it difficult to identify antigens for b

184 er, our results demonstrate that the E. coli adhesin MAM(HS) facilitates retention of a gut commensal

185 polymeric microbeads functionalized with the adhesin MAM7 to a burn infected with multidrug-resistant

186 ever, sequence variability among the class 5 adhesins may hinder the generation of cross-protective a

187 Bacterial adhesins mediate adhesion to substrates and biofilm form

188 rticipate in biofilm biogenesis and the EmaA adhesins mediate collagen binding.

189 The BabA adhesin mediates high-affinity binding of Helicobacter p

190 suggesting that a single galactose-sensitive adhesin might mediate the interaction of fusobacteria wi

191 ve cycle of T. gondii including secretion of adhesins, motility, invasion, and egress.

192 its in vivo include trimeric autotransporter adhesins, O antigens, and type IV pili (T4P).

193 of the in cis donor strand-complemented tip adhesin of a colonization factor of the class 5 family (

194 EfbA is a PavA-like fibronectin adhesin of Enterococcus faecalis previously shown to be

195 al collagen-like protein 1 (Scl1) is a major adhesin of GAS that selectively binds to two fibronectin

196 Hia is a major adhesin of nontypeable Haemophilus influenzae (NTHi) and

197 Previous studies of GspB (the SRR adhesin of Streptococcus gordonii) have shown that a gly

198 P1 (antigen I/II) is a sucrose-independent adhesin of Streptococcus mutans whose functional archite

199 emal protein 2 (MIC2), a motility-associated adhesin of T. gondii, has highly glycosylated thrombospo

200 We show that the major adhesin of the pneumococcal pilus-1, RrgA, binds both re

201 e focused on the antigenically conserved tip adhesins of colonization factors.

202 Adhesins of the LPXTG family are posttranslationally pro

203 Genes encoding adhesins of the oral bacterium Streptococcus gordonii we

204 egarding pilus stiffness and the location of adhesins on pili.

205 against CFA/I minor pilin subunit (CfaE) tip adhesin or colonization factor I (CFA/I) fimbraie (posit

206 ocused predominantly on the role of parasite adhesins or signaling pathways and the identity of bindi

207 ease with O7 serogroup (P = .034) and PapGII adhesin (OR, 2.3 [95% CI, 1.2-4.5], P = .015).

208 The virulence factor S. suis adhesin P (SadP) recognizes the galabiose Galalpha1-4Gal

209 operon, which encodes another important UPEC adhesin, P fimbria.

210 riogenic bacterium Streptococcus mutans uses adhesin P1 to adhere to tooth surfaces, extracellular ma

211 dently from the polysaccharide intercellular adhesin PIA.

212 In addition to polysaccharide intercellular adhesin (PIA) and extracellular DNA, surface proteins ap

213 oduction of the polysaccharide intracellular adhesin (PIA) in either strain because the amount of PIA

214 opolysaccharide polysaccharide intercellular adhesin (PIA) were central to the regulatory impact of R

215 e production of polysaccharide intercellular adhesin (PIA), a well-characterized, robust matrix molec

216 es, such as the polysaccharide intercellular adhesin (PIA), with the bacterial cell surface.

217 , we have established that the HMW1 and HMW2 adhesins play a major role in facilitating colonization

218 s cells carrying pCF10 produce three surface adhesins (PrgA, PrgB or Aggregation Substance, PrgC) and

219 PrgA can interact with another enterococcal adhesin, PrgB, and that these two proteins have co-evolv

220 dhesion (31.6% vs 17.8%) and upregulation of adhesin protein Als5p.

221 -molecule force spectroscopy to show that an adhesin protein can regenerate its thioester in the abse

222 The major adhesin protein P1 mediates adherence to terminal sialic

223 mbrane vesicles containing YadA, a bacterial adhesin protein, were prepared.

224 orrelated with reduced expression of the Flp adhesin proteins in the (p)ppGpp mutant but not in the d

225 n is required for the export and function of adhesin proteins that mediate the attachment of pathogen

226 produce a unique set of defined glucosylated adhesin proteins.

227 glycosylate the serine-rich repeat (SRR) of adhesin PsrP (pneumococcal serine-rich repeat protein),

228 at was inhibited by blocking or mutating the adhesin RadD on Fusobacterium and removal of flagella on

229 in bacterial colonization, and the nature of adhesin-receptor interactions determines bacterial local

230 ns of streptococcal serine-rich repeat (SRR) adhesins recognize sialylated glycans on human salivary,

231 ted from Denmark, suggesting that this novel adhesin represents an important variant.

232 ow that they promote expression of the curli adhesin, repress the expression of tryptophan metabolism

233 nding protein homolog 5 (PfRH5), a merozoite adhesin required for erythrocyte invasion, is highly sus

234 face exposition of various proteins, such as adhesins, required for gliding motility in Flavobacteriu

235 eumococcal pilus-1, which includes the pilus adhesin RrgA, promotes bacterial penetration through the

236 glands, in situ, through interaction of its adhesin, SabA, with sialyl-Lewis X, which expanded in SP

237 f the scaCBA operon encoding the lipoprotein adhesin ScaA, which was sufficient to preserve and even

238 dings indicate that the dscCfaE fimbrial tip adhesin serves as a protective passive vaccine antigen i

239 e galabiose-binding domain of type P(N) SadP adhesin showed that the amino acid asparagine 285, which

240 In tissue, Scl1 adhesin specifically recognizes the wound microenvironme

241 al reactivity patterns, including individual adhesin specificity, intrasubclass specificity, intersub

242 These include the surface adhesin SprB that forms filaments about 160 nm long by 6

243 The propulsion of a cell-surface adhesin, SprB, is known to enable gliding.

244 Studying the pilus tip adhesin Spy0125 of Streptococcus pyogenes, we developed

245 P-10, which possibly relied on a serine-rich adhesin (sraP) gene detected on the pLPE-2 plasmid.

246 s.S. sanguinisexpresses a serine-rich repeat adhesin, SrpA, similar in sequence to platelet-binding a

247 Here, we describe a novel S. sonnei adhesin, SSO1327 which is a multivalent adhesion molecul

248 ly, these findings establish a new bacterial adhesin structure that has in effect been hijacked by a

249 roteolytic cleavage of endothelial cell-cell adhesins such as PECAM-1.

250 Members of the Trimeric Autotransporter Adhesin (TAA) family play a crucial role in the adhesion

251 ogenesis of UpaG, a trimeric autotransporter adhesin (TAA).

252 -related gene encoding a yet-uncharacterized adhesin, termed agg5A.

253 y discovered a widespread group of bacterial adhesins, termed Multivalent Adhesion Molecules (MAMs) t

254 ecifically associates with the transmembrane adhesin TgMIC2.

255 nized functions in addition to serving as an adhesin that binds Le(b).

256 EtpA is a secreted two-partner adhesin that is conserved within the ETEC pathovar.

257 that PKG regulates the secretion of TRAP, an adhesin that is essential for motility.

258 2 is a galactose-sensitive hemagglutinin and adhesin that is likely to play a role in the virulence o

259 As an adhesin that promotes bacterial interaction with fibrone

260 ri and show that HopQ is the surface-exposed adhesin that specifically binds human CEACAM1, CEACAM3,

261 y to OmpA of A. phagocytophilum (ApOmpA), an adhesin that uses key lysine and glycine residues to int

262 data suggest that EmaA is a multifunctional adhesin that utilizes different mechanisms to enhance ba

263 , which are extracellular fibers tipped with adhesins that bind mucosal surfaces of the urinary tract

264 process is facilitated by cell wall-anchored adhesins that bind to host ligands.

265 cteria carry filamentous polypeptides termed adhesins that enable binding to both biotic and abiotic

266 ues requires the presence of surface-exposed adhesins that have been difficult to identify due to the

267 SRRPs are a family of bacterial adhesins that have diverse roles in adhesion and that ca

268 itive bacteria are large, cell wall-anchored adhesins that mediate binding to many host cells and pro

269 t the NTHi HMW1 and HMW2 proteins are potent adhesins that mediate efficient in vitro adherence to cu

270 e is an obligate intracellular organism, its adhesins that mediate entry into host cells are essentia

271 tion in surface-exposed molecules, including adhesins that promote host colonization.

272 omains function as ligand-binding domains in adhesins that support cell adhesion and migration in man

273 w paradigm for target binding by a bacterial adhesin, the identification of which will inform future

274 The pilus adhesin tip protein Cpa promoted Alab49 survival in whol

275 Expression of ace (adhesin to collagen of Enterococcus faecalis), encoding

276 tes of inflammation, and allow the bacterial adhesin to selectively associate with surface-bound liga

277 ermed a smart covalent bond) could allow the adhesin to undergo binding and unbinding to surface liga

278 we uncover higher order binding of microbial adhesins to clustered patches of O-glycans organized by

279 al spike proteins, the relationship of these adhesins to mammalian galectins was examined by computat

280 Gram-positive surrogate that otherwise lacks adhesins to mammalian ligands.

281 Some phages need to acquire specific adhesins to overcome the O-antigen layer.

282 brium reactivity allows thioester-containing adhesins to sample potential substrates without irrevers

283 equently based on the binding of lectin-like adhesins to specific glycan determinants exposed on host

284 g sortase responsible for covalently linking adhesins to the cell wall.

285 One such UPEC adhesin is the nonfimbrial adhesin TosA, which mediates adherence to the epithelium

286 Two pKM101-encoded proteins, the pilus-tip adhesin TraC and a protein termed Pep, are exported to t

287 esentation of cell wall synthesis machinery, adhesins, transporter solute-binding proteins, and degra

288 These adhesins typically have a 90-amino acid-long signal pept

289 hmwA, which encodes the HMW adhesin, undergoes phase variation mediated by 7-base pa

290 spAB), both of which encode LPXTG-containing adhesins, unexpectedly enhanced adhesion and biofilm for

291 ine triad protein D (PhtD), an S. pneumoniae adhesin vaccine candidate, for its ability to prevent in

292 slocation of apically secreted transmembrane adhesins via their interaction with the parasite actomyo

293 cells and, further, that expression of this adhesin was required for the enhanced adherence observed

294 st host proteins recognized by S. pneumoniae adhesins, we showed that S. pneumoniae uptake by cardiom

295 the vicinity of binding pocket-Ser155 for Dr-adhesin were mutated to alanine and subjected to tempora

296 cytoplasmic proteins were more common, while adhesins were less common compared to findings on protec

297 known as multivalent adhesion molecule 7, an adhesin which mediates the initial stages of attachment

298 Helicobacter pylori strains express the BabA adhesin, which binds to ABO/Leb blood group antigens on

299 definitive identification of a C. difficile adhesin, which now allows work to devise improved measur

300 ion, and egress by connecting the micronemal adhesins with the actomyosin system.