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1 res of an integrin-like extracellular matrix adhesion receptor.
2 of focal adhesion kinase and integrin alpha5 adhesion receptor.
3 r tyrosine kinase that acts as a collagen IV adhesion receptor.
4 in persons with high levels of this soluble adhesion receptor.
5 , CX3CR1 has been proposed to function as an adhesion receptor.
6 tion and inhibiting its function as a matrix adhesion receptor.
7 RAIL) on their surface along with E-selectin adhesion receptor.
8 remodeling of F-actin and redistribution of adhesion receptors.
9 arity is regulated in part by signaling from adhesion receptors.
10 tly by inadequate expression of cell surface adhesion receptors.
11 in driving the lateral, cis-, clustering of adhesion receptors.
12 motif that can bind to cell-surface integrin adhesion receptors.
13 ng in addition to their well-defined role as adhesion receptors.
14 herin would affect expression of cell matrix adhesion receptors.
15 te for the cytoplasmic tails of the integrin adhesion receptors.
16 1 and occupies the binding site for integrin adhesion receptors.
17 chronous sideways movement of beta1 integrin adhesion receptors.
18 sequence similarity to known matrix protein adhesion receptors.
19 substrates capable of engaging specific cell-adhesion receptors.
20 s the modulation of the affinity of integrin adhesion receptors.
21 ress high levels of beta1 and beta2 integrin adhesion receptors.
22 rease in the functional activity of integrin adhesion receptors.
23 dentified for a member within this family of adhesion receptors.
24 al cooperativity between integrins and other adhesion receptors.
25 and down-regulating cytokine, chemokine, and adhesion receptors.
26 nderstanding the regulation of integrin cell adhesion receptors.
27 ell migration initiated by growth factor and adhesion receptors.
28 ation is initiated by the selectin family of adhesion receptors.
29 tral property of the integrin family of cell adhesion receptors.
30 performed in animal models deficient in both adhesion receptors.
31 ation of the beta(1) integrin family of cell adhesion receptors.
32 d to various chemotactic signals and express adhesion receptors.
33 othelial surface by altering the dynamics of adhesion receptors.
34 olding may be applicable for many other cell adhesion receptors.
35 rotein ELMO, downstream of cell-surface cell-adhesion receptors.
36 the binding specificities and energetics of adhesion receptors.
37 pholipase D (lysoPLD) that binds to integrin adhesion receptors.
38 ment are dependent on the integrin family of adhesion receptors.
39 egulated changes in the affinity of integrin adhesion receptors ("activation") play an important role
40 1-MMP proteolysis of the T cell surface CD44 adhesion receptor affects the homing of T cells into the
41 as to the mechanism of lateral clustering of adhesion receptors after cell-cell contact and, more gen
42 down-regulated the expression of major cell adhesion receptors (alphav and beta3 integrins), matrix
43 in receptor, alpha(5)beta(1)-integrin, as an adhesion receptor and in angiogenesis is well establishe
45 activated by engagement of several leukocyte adhesion receptors and contribute to both early morpholo
46 migration, rather little is known about the adhesion receptors and extracellular matrix molecules in
47 t is likely that analysis of the spectrum of adhesion receptors and extracellular matrix proteins can
49 mposed of clusters of transmembrane integrin adhesion receptors and intracellular proteins that link
51 Cell invasion requires cooperation between adhesion receptors and matrix metalloproteinases (MMPs).
53 ar signaling pathways, which are mediated by adhesion receptors and other transducers of extracellula
54 are regulated by a controlled interaction of adhesion receptors and proteases, and late metastasis is
55 on and invasion and endocytic trafficking of adhesion receptors and signaling proteins plays a major
56 d to cell surfaces through interactions with adhesion receptors and sulfated glycolipids (Figure 1, b
57 ate the steady-state levels of signaling and adhesion receptors and that loss of these proteins can c
58 tes mitochondrial injury-induced shedding of adhesion receptors and that TACE activity correlates wit
59 ha-actinin with actin filaments and integrin adhesion receptors and that the dynamics of alpha-actini
61 ubunit member of the integrin family of cell adhesion receptors and was found to activate complex of
62 an essential role in activation of integrin adhesion receptors, and expression of at least 1 Kindlin
63 w the actin cytoskeleton and its regulators, adhesion receptors, and scaffolding proteins mediate syn
64 These results document a novel mechanism of adhesion receptor- and pulmonary chemokine-dependent reg
67 nals linking the actin cytoskeleton and cell adhesion receptors are essential for morphogenesis durin
68 f membrane bound (2D) and freely moving (3D) adhesion receptors are expressed and compared using elem
71 Moreover, a2NTD treatment activates surface adhesion receptors, as well as FAK and Src kinases that
73 ication between an inflammatory mediator and adhesion receptors at a molecular level, through selecti
74 here that in rat and mouse, hippocampus cell adhesion receptors belonging to the beta1-integrin famil
75 esent study provides the first evidence that adhesion receptors belonging to the integrin family modu
77 o examine the role of the signaling and cell-adhesion receptor beta 4 integrin during ErbB2-mediated
78 combination of chemokine receptor (CCR2) and adhesion receptor (beta2 integrin) engagement leads to a
79 PTP)-PEST and the extracellular matrix (ECM) adhesion receptor beta8 integrin that plays essential ro
84 s not function as a neutrophil phagocytic or adhesion receptor, but may instead serve as a sugar-bear
88 al that integrin alphaIIbbeta3, a prototypic adhesion receptor, can be activated by various mechanica
92 hRNA screens, we identified the cell-surface adhesion receptor CD44 as a key positive regulator of PD
93 cortical patches, decreased abundance of the adhesion receptor CD44 at membrane protrusions, and atte
94 ve actin assembly and down-regulation of the adhesion receptor CD44 in MM HSPCs functionally reflecte
95 rs the splicing pattern of mRNA encoding the adhesion receptor CD44, promoting exon inclusion, and de
98 main; and (iii) N-glycosylated transmembrane adhesion receptors complexed with tetraspanin and gangli
100 , which represent a major group of cell-cell adhesion receptors contributing to embryonic neuronal mo
101 Activation (affinity regulation) of integrin adhesion receptors controls cell migration and extracell
104 approximately 45 min period during which the adhesion receptors did not respond to a second applicati
107 s in endothelial expression of the leukocyte adhesion receptor E-selectin and in microvascular leukoc
108 them to the Hippo pathway, whereas the cell-adhesion receptor Echinoid evolved as a new protein.
109 nclude members of the integrin family of ECM adhesion receptors, ECM proteins such as Wnts and latent
110 buted to adhesion, it is understandable that adhesion receptor engagement has been reported to alter
111 mig-38 and ina-1, which encodes an integrin adhesion receptor, enhanced the loss of turning phenotyp
112 lung metastatic capability in vivo The cell adhesion receptor EphA4 was determined to be a direct ta
113 oupling is usually mediated by transmembrane adhesion receptors, especially those of the integrin fam
114 rins are abundant heterodimeric cell-surface adhesion receptors essential in multicellular organisms.
115 to our knowledge the first example of a cell adhesion receptor exhibiting retrograde nuclear traffick
117 PDK1 determines the cohort of chemokine and adhesion receptors expressed by PTEN-null cells, thereby
118 itate metastasis through binding to selectin adhesion receptors expressed on platelets, leukocytes an
120 ll adhesion molecule-1, while characterizing adhesion receptor expression and topography on captured
121 monocyte subset as a function of changes in adhesion receptor expression using flow cytometric quant
126 lipase C pathway or the hindrance of surface adhesion receptors failed to impede PLT anti-S. aureus r
127 either the transmembrane isoform of the cell adhesion receptor fasciclin II (TM-MFas II) or the glyco
128 ults support a model where the engagement of adhesion receptors first activates talin or alpha-actini
129 ha-actinin with actin filaments and integrin adhesion receptors, fluorescence recovery after photoble
131 (very late antigen-1; CD49a/CD29) is a major adhesion receptor for collagen I, IV, and VI, and its in
133 ntegrin alpha6beta4 is an essential, dynamic adhesion receptor for laminin 332 found on epithelial ce
135 E-selectin, an endothelial cell surface adhesion receptor for leukocytes, also acts as a signali
136 onstrate the existence of a novel functional adhesion receptor for PS on the microendothelium that is
137 ns display carbohydrate facets that serve as adhesion receptors for cells including leukocytes and ba
138 is study adds to the classes of cell-surface adhesion receptors for FN and will help in the further c
139 L-SIGN), encode C-type lectins that serve as adhesion receptors for ICAM-2 and ICAM-3 and participate
140 collin 1 (Dsc1) is part of a desmosomal cell adhesion receptor formed in terminally differentiating k
142 The activation of heterodimeric integrin adhesion receptors from low to high affinity states occu
143 activation, the rapid conversion of integrin adhesion receptors from low to high affinity, occurs in
147 genic growth factor, VEGF, and integrin cell adhesion receptors has emerged recently as a critical fa
148 sion efficiency, and lateral organization of adhesion receptors has not been established for any adhe
149 During inflammation, leukocytes bind to the adhesion receptors ICAM-1 and VCAM-1 on the endothelial
150 ng PDA, however, a causal role for this cell adhesion receptor in disease progression has yet to be d
151 important signaling receptor rather than an adhesion receptor in vivo and therefore promote beta1 in
153 which these molecules interact with integrin adhesion receptors in and outside the neuronal tissues.
159 pillary venules and requires a unique set of adhesion receptors including peripheral node addressin,
163 ecific for the activated conformation of the adhesion receptor integrin alphavbeta3 that is associate
165 surface levels of the progression-associated adhesion receptors integrin alpha2beta1 and CD44 were di
166 n of the ligand binding affinity of integrin adhesion receptors (integrin activation) depends on the
167 ding model by showing that the main podocyte adhesion receptor, integrin alpha3beta1, interacts with
169 CN1 induces fibroblast apoptosis through its adhesion receptors, integrin alpha6beta1 and the heparan
171 ls sense the extracellular environment using adhesion receptors (integrins) linked to the intracellul
174 , leading to expression of the key leukocyte adhesion receptors intercellular adhesion molecule 1 (IC
175 ry late antigen-4 (VLA-4), CD49d/CD29) is an adhesion receptor involved in the interaction of lymphoc
176 llular cell adhesion molecule 1 (ICAM-1), an adhesion receptor involved in the recruitment of leukocy
181 al by the EGFR and extracellular matrix/cell adhesion receptors is enabled, in part, by shared signal
183 ed member of the beta2 subfamily of integrin adhesion receptors, is up-regulated on macrophage foam c
186 XCL)12, CXCL13, and CCL19, and expression of adhesion receptors L-selectin, alpha(4)beta(7), and CLA.
187 ax to most chemokines and do not express the adhesion receptors L-selectin, alpha(4)beta(7), and cuta
189 lls with an antibody against the erythrocyte adhesion receptor Landsteiner-Wiener (intercellular adhe
191 integrins with cognate immunoglobulin class adhesion receptor ligands is an effective neuroprotectiv
195 ic domains (tails) of heterodimeric integrin adhesion receptors mediate integrins' biological functio
196 alin, to the cytoplasmic domains of integrin adhesion receptors mediates bidirectional signal transdu
197 pattern recognition receptor but also as an adhesion receptor mediating clustering between LCs and d
198 identified integrin alphaMbeta2 as the major adhesion receptor mediating monocyte adhesion to CCN1 an
200 In the course of studies to investigate the adhesion receptors mediating sickle RBC-WBC interactions
201 bilayers of protein clusters containing the adhesion receptor Nephrin and its cytoplasmic partners,
203 hesion cascade involving interaction between adhesion receptors of endothelial cells and ligands on C
207 Activation of the integrin family of cell adhesion receptors on progenitor cells may be a viable a
209 addition to its regulating the expression of adhesion receptors on the yeast, we have found that hemo
213 cally engineered mice lacking major platelet adhesion receptors or their activators (alphaIIbbeta3, g
214 DLN T cells expressing binding sites for the adhesion receptor P-selectin (Plig(high) T cells) produc
215 pressure causes exocytosis of the leukocyte adhesion receptor P-selectin in endothelial cells (ECs),
216 trusions, known as knobs, where the parasite adhesion receptor P. falciparum erythrocyte membrane pro
217 th those elicited by the inhibitory platelet adhesion receptor PECAM-1 (platelet endothelial cell adh
220 On the intracellular face of these linkages, adhesion receptors - principally integrins and syndecans
226 s interactions between surface Neph1/nephrin adhesion receptors Roughest and Hibris, which bind the a
228 us and mating type minus gametes mediated by adhesion receptors SAG1 and SAD1 activate a ciliary sign
229 eractions of this protein with its different adhesion receptors, Sag1 and Fig2p, a property of many h
231 A substrate fusion protein composed of yeast adhesion receptor subunit Aga2, selection and countersel
232 ts establish that genetic differences in the adhesion receptor subunits alpha(2), alpha(IIb,) and GPV
233 posure to GM-CSF followed by the ligation of adhesion receptors such as CD44, CD11b, CD18, or CD15.
235 -endothelial migration (TEM), leukocytes use adhesion receptors such as intercellular adhesion molecu
236 rimary cause of breast cancer mortality, and adhesion receptors, such as CD44, are believed to be cri
238 3, a marker of mature dendritic cells, is an adhesion receptor that binds to resting monocytes and a
239 bbeta3 is a transmembrane (TM) heterodimeric adhesion receptor that exists in equilibrium between res
240 E-cadherin, an intercellular N-glycoprotein adhesion receptor that functions in the assembly of mult
241 -1, also called TMIGD2) gene as a novel cell adhesion receptor that is expressed in various human org
242 tercellular adhesion molecule-1 (ICAM-1), an adhesion receptor that mediates inflammatory and immune
245 ntigen 1 (LFA-1; CD11a/CD18) is a key T cell adhesion receptor that mediates stable interactions with
246 rker CEACAM6, a highly abundant cell surface adhesion receptor that modulates the extracellular matri
247 ta1 integrin, CD49d/CD29) is a transmembrane adhesion receptor that plays an important role in cancer
248 ed whether microendothelial cells express an adhesion receptor that recognizes cell surface-expressed
250 The integrins make up a large family of cell adhesion receptors that are known to mediate bidirection
251 n and trafficking.Integrins are cell-surface adhesion receptors that are modulated by endo-exocytic t
256 eterodimeric alpha/beta extracellular matrix adhesion receptors that couple physically to the actin c
257 stimuli would lead to surface expression of adhesion receptors that facilitate the binding of circul
259 gnaling kinase cascade typically employed by adhesion receptors that involves upstream Src and FAK fa
261 es of 24 alphabeta heterodimer transmembrane adhesion receptors that mediate cell-cell and cell-extra
263 Integrins comprise a large family of cell adhesion receptors that mediate diverse biological event
266 s are a family of heterodimeric (alpha+beta) adhesion receptors that play key roles in many cellular
268 staining for beta1 integrin, a component of adhesion receptors that regulate synapse maintenance and
269 ector molecules, and essential chemokine and adhesion receptors that regulate T cell trafficking.
271 ukocyte)-selectin (CD62L) and CD44 are major adhesion receptors that support the rolling of leukocyte
273 Integrins are a family of heterodimeric adhesion receptors that transmit signals bi-directionall
274 oting antigenic polymorphisms and/or diverse adhesions-receptors that may be involved in immune evasi
276 l-cell adhesion by interacting with cadherin adhesion receptors through beta-catenin, but the mechani
277 ned suggest that sadA is the first substrate adhesion receptor to be identified in Dictyostelium.
278 ronment and use the high-affinity form of an adhesion receptor to grow and secure host support for pr
279 ed the functional relationship between these adhesion receptors to determine how it regulates cell tr
281 atelets and show that adherent platelets use adhesion receptors to mechanically probe the adhesive su
283 vation, and the failure to recruit essential adhesion receptors to the membrane contact site formed w
285 ions of Astn1 and Astn2, such as in membrane adhesion, receptor trafficking, and planar polarity sign
289 Cell migration during wound healing requires adhesion receptor turnover to enable the formation and d
290 lasmic tails regulate activation of integrin adhesion receptors via clasping/unclasping of their memb
292 CR1 have been previously shown to bind viral adhesion receptors, we speculate that NKp46/NCR1 may be
293 The distribution of membrane lipid rafts and adhesion receptors were analyzed by imaging flow cytomet
294 antibodies to red blood cell and endothelial adhesion receptors were used in vitro and in vivo to pro
295 ity (WRAMP) structure, which integrates cell-adhesion receptors with F-actin and myosin to form a mic
296 ombi is mediated by interactions of platelet adhesion receptors with ligands on the injured endotheli
298 is identified as the dominant staphylococcal adhesion receptor, with Fnbps playing a supporting role.
299 ptor-treated mice showed alterations in cell adhesion receptors, with reduced CXCR2 and increased CD6
300 ycosylated receptors, immune receptors, cell adhesion receptors, Wnt receptors, and receptor tyrosine