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1 ng solid cancers utilizing viral vectors and adoptive cell transfer.
2 ty while retaining a favorable phenotype for adoptive cell transfer.
3 to T cells, and ex vivo clonal expansion for adoptive cell transfer.
4 TME-localized inhibitory molecules following adoptive cell transfer.
5 and regress multiple solid tumors following adoptive cell transfer.
6 ine delivery or optimal T cell expansion for adoptive cell transfer.
7 tive target for TCR-based gene therapy using adoptive cell transfer.
8 r tumor rejection or inhibit treatment after adoptive cell transfer.
9 e of circulating antitumor T cells following adoptive cell transfer.
10 N-gamma-/- mice, were used as recipients for adoptive cell transfer.
11 tive vaccines and strategies for therapeutic adoptive cell transfer.
12 lymphocytes from melanoma patients following adoptive cell transfer.
13 pulations were rejected within 18 days after adoptive cell transfer.
14 ns and reducing the therapeutic potential of adoptive cell transfers.
15 such as administration of the cytokine IL-2, adoptive cell transfer (ACT) and the recent success of b
17 , T cell expansion and persistence following adoptive cell transfer (ACT) have correlated with superi
24 umor microenvironment (TME), the efficacy of adoptive cell transfer (ACT) is much curtailed in treati
26 the potential for immunotherapy based on the adoptive cell transfer (ACT) of engineered T lymphocytes
30 immunotherapies, including cancer.IMPORTANCE Adoptive cell transfer (ACT) of T cells engineered with
34 2 (IL-2) is a component of most protocols of adoptive cell transfer (ACT) therapy for cancer, but is
37 dy that describes a potential new target for adoptive cell transfer (ACT), in this case CD44 splice v
38 esponse is enhanced through a combination of adoptive cell transfer (ACT), specific vaccination and c
43 f successful cancer immunotherapies, such as adoptive cell transfer and antibody-based immunotherapeu
45 its functional loss reduces the efficacy of adoptive cell transfer and checkpoint blockade immunothe
47 r, did not require total body irradiation or adoptive cell transfer and resulted in induction of anti
48 ls, with potential clinical implications for adoptive cell transfer and vaccine-based immunotherapies
50 ncer vaccines, immune checkpoint inhibitors, adoptive cell transfer, and bispecific antibody therapy.
51 ts for successful tumor rejection through an adoptive cell transfer approach reveals that the presenc
53 ere dissected using bone marrow chimeras and adoptive cell transfer approaches to profile clonal expa
55 eric antigen receptor (CAR) for T-cell-based adoptive cell transfer are among these developments that
57 chronically-stimulated T cells expanded for adoptive cell transfer are susceptible to cell death in
58 erged as an important component of effective adoptive cell transfer-based immunotherapy for cancer.
61 upport suggests that IL-12 could be added to adoptive cell transfer clinical strategies in cancer pat
62 aded with the calcium nanoparticles prior to adoptive cell transfer control tumor growth better, resu
68 Furthermore, use of gene-deficient mice and adoptive cell transfer experiments revealed that ILC2s w
69 ent tumor models suppressed CTL responses in adoptive cell transfer experiments unless GM-CSF was pro
70 tumor-sensitized T cells is demonstrated by adoptive cell transfer experiments using purified spleen
75 the main challenge to the development of TIL adoptive cell transfer for metastatic GI cancers may not
76 immune-checkpoint blockade, vaccination, and adoptive cell transfer have been extensively studied in
77 apies such as immune checkpoint blockade and adoptive cell transfer have revolutionized cancer treatm
78 -1/PD-L1 and CTLA-4 checkpoints blockade and adoptive cell transfer) have remarkably improved the res
79 ivated CD8 T cell function in the context of adoptive cell transfer, however, has not been explored i
80 ith porcine skin grafts and administered, by adoptive cell transfer, human cells stimulated in vitro
82 corporating tumor-reactive CD4(+) T cells in adoptive cell transfer immunotherapies against ovarian c
85 engineer a wide range of cell types used in adoptive cell transfers, including erythrocytes, macroph
88 cell compartment in immunodeficient mice by adoptive cell transfer leads to a wasting syndrome and i
89 for administering high levels of IL-2 during adoptive cell transfer-mediated antitumor responses.
92 re analyzed using cytokine reporter mice, an adoptive cell transfer model, and gene knockout mice.
96 six patients were enrolled on a protocol of adoptive cell transfer of enriched neoantigen-specific T
100 us immunotherapies under development such as adoptive cell transfer of TCR-engineered CD8(+) T cells,
104 re implanted into Rag-/- animals followed by adoptive cell transfer of WT or CD8DeltaALK5 OT-I T cell
105 clonotypes that persisted in vivo following adoptive cell transfer possessed telomeres that were lon
107 -engineered T cells are a novel approach for adoptive cell transfer, providing flexible platform for
115 e significant progress in the development of adoptive cell-transfer therapies (ACTs) using gene-engin
119 hways (i.e. PD-1, CTLA-4, and IDO); and (iv) adoptive cell transfer therapy with T cells engineered t
120 e yielded only limited clinical success, but adoptive cell transfer therapy, particularly following a
121 hough IL-9 has potent anti-tumor activity in adoptive cell transfer therapy, some models suggest that
122 with chemo-immunotherapy, nanomedicine, and adoptive cell transfer therapy, we aim to lay the ground
124 ies such as immune checkpoint inhibitors and adoptive cell transfer, TILT-123 (Ad5/3-E2F-D24-hTNFalph
125 s including laser-Doppler perfusion imaging, adoptive cell transfer to ischemic muscle, immunoblot an
127 ession of CTLs that is often observed during adoptive cell transfer tumor immunotherapy and identify
129 s study, using conditional knockout mice and adoptive cell transfer, we found that moDCs are essentia
130 mice missing different leukocyte subsets and adoptive cell transfers, we demonstrated the involvement