ライフサイエンスコーパス: adult rat

1 PNS (sensory) but not CNS (retinal) axons in adult rat.

2 rent aspects of executive functioning in the adult rat.

3 a play a critical role in this incubation in adult rats.

4 from aged rats compared to those in younger adult rats.

5 tory exploration and same-sex recognition of adult rats.

6 lete low-thoracic spinal cord transection in adult rats.

7 We generated controlled cortical impacts in adult rats.

8 n vivo in a model of chemical denervation in adult rats.

9 d schizophrenia, and in chronically-stressed adult rats.

10 breathing vagotomized urethane-anesthetized adult rats.

11 rainstem after brachial dorsal root crush in adult rats.

12 lasticity in postweanling pups compared with adult rats.

13 ty of layer 5 mPFC-BLA projection neurons in adult rats.

14 in extinction could exist in adolescent and adult rats.

15 se to cocaine administration in anesthetized adult rats.

16 ut not LTD at MF synapses of freely behaving adult rats.

17 tate gyrus (mPP-DG) synapses in juvenile and adult rats.

18 tion learning in adolescent rats, but not in adult rats.

19 in the primary cultured cardiomyocytes from adult rats.

20 ollowing unilateral C4 spinal hemisection in adult rats.

21 an be rapidly modified by reward training in adult rats.

22 forms of BLA hyperactivity in adolescent and adult rats.

23 d in the articular cartilage chondrocytes of adult rats.

24 d environment (EE) promotes OD plasticity in adult rats.

25 al disturbances on indices of DA function in adult rats.

26 lity during the task than either juvenile or adult rats.

27 natal insult blocked the induction of GHS in adult rats.

28 y injection of axonal anterograde tracers in adult rats.

29 d in neurons of dorsal root ganglia (DRG) of adult rats.

30 ritic morphology of dentate gyrus neurons in adult rats.

31 after a thoracic spinal cord hemisection in adult rats.

32 e thoracic transection of the spinal cord in adult rats.

33 e thoracic spinal cord transection lesion in adult rats.

34 rn neurons of spinal slices taken from young adult rats.

35 mized, anesthetized, spontaneously breathing adult rats.

36 ficantly more slowly than either juvenile or adult rats.

37 ein into the T4 complete transection site of adult rats.

38 nd lowers ovarian reserve in next-generation adult rats.

39 xtracellular stimulation method in young and adult rats.

40 the brainstem of adult macaques compared to adult rats.

41 es, including the gastro-intestinal tract of adult rats.

42 ter synaptic transmission in the PFC of male adult rats.

43 e-cell patch-clamp recordings in slices from adult rats.

44 focused attention and arousal regulation in adult rats.

45 dy (CB) chemosensory reflex were examined in adult rats.

46 ical areas after bilateral deafness in young adult rats.

47 pi (CA1 and CA3) of moderate PAE and control adult rats.

48 l cortices after auditory deprivation in the adult rats.

49 Experiments were conducted in adult rats.

50 propria containing the myenteric plexus from adult rats.

51 amatergic drive of LAT projection neurons in adult rats.

52 dy (CB) chemosensory reflex were examined in adult rats.

53 slice cultures and acute brainstem slices of adult rats.

54 In adult rats, 3.6% +/- 0.9% of cells still proliferate, wh

55 In contrast, in the mPFC of adult rats 5 weeks after they received nicotine treatmen

56 In juvenile and adult rats, a single class of USV is observed with an ag

57 We conclude that in anesthetized adult rats active expiration is driven by the pFL but re

58 dide(DiR)-labeled liposomes was evaluated in adult rats after single intravenous injection at dose of

59 Here, we show that axons in the adult rat amygdala contain translation machinery, and us

60 piriform cortex were sparser than typical in adult rat and did not enlarge with learning.

61 gions, including sensory nuclei, in both the adult rat and human, where it may regulate neuronal func

62 h light (LM) and electron microscopy (EM) in adult rat and mouse brain.

63 ative data on the anatomy of the nLOT in the adult rat and on the effects of age on its structure and

64 bead formation in the dendrites and axons of adult rat and rabbit retinal ganglion cells, and that re

65 e the cardiac side effects of doxorubicin in adult rats and decipher whether signaling pathways invol

66 rich fraction was isolated from the blood of adult rats and human volunteers and was analyzed by prot

67 Consistently with their role, in adult rats and humans, LSt neurons are sexually dimorphi

68 y means of the elevated plus maze in control adult rats and in adult rats subjected to early EE or to

69 Here we show in young adult rats and mice that learning the hippocampus-depend

70 CSD was elicited chemically in adult rats and occurrence, amplitude, duration and propa

71 f amygdala provoked anxiety in alcohol-naive adult rats and recapitulated the molecular and epigeneti

72 icular nucleus (PaVN) of the hypothalamus of adult rats and results in discrete behavioral changes.

73 We analyze lumbar motor patterns of intact adult rats and the same rats after spinal transection an

74 1 pyramidal cells in hippocampal slices from adult rats and used specific inhibitors of kinases and c

75 e ethanol-induced anxiolysis was measured in adult rats, and amygdaloid tissues were used for miRNA p

76 growth plate (AG) cartilage chondrocytes in adult rats, and superficial layer (IS) versus deep layer

77 vade the CRF receptor system in juvenile and adult rats, and the mechanisms that control them are lik

78 t grafted into the transected spinal cord of adult rats as a supportive environment for regeneration

79 antly down-regulated after focal ischemia in adult rats as well as after oxygen-glucose deprivation i

80 ial cells of the ventral cochlear nucleus in adult rats at 1, 7, 15, and 30 days following bilateral

81 klotho mRNA expression in the developing and adult rat brain and report moderate, widespread expressi

82 d a DPP10 antibody to label DPP10 protein in adult rat brain by immunohistochemistry.

83 related downstream proteins was detected in adult rat brain exposed to MeHg (0 - 10 mg/kg) for 0.5 h

84 Adult rat brain microglia (resting or activated with lip

85 Immunoelectron microscopy of the adult rat brain showed that GluN2D is predominantly expr

86 ghly expressed in O4(+) OL precursors of the adult rat brain than those of the neonatal brain.

87 I and -URP binding site distributions in the adult rat brain, and found that they fully overlapped at

88 here that NDCBE is expressed throughout the adult rat brain, and selectively concentrates in presyna

89 postnatal weeks, it is also expressed in the adult rat brain.

90 -resolution 3-D MRI atlas of the Fischer 344 adult rat brain.

91 rate that IRSp53 is expressed throughout the adult rat brain.

92 both isoforms in PSD fractions isolated from adult rat brain.

93 ly in peripheral astroglial processes in the adult rat brain.

94 ha and related downstream target proteins in adult rat brain.

95 Twenty-six healthy human adults rated brushing on the hand during fMRI.

96 lasmids into the tibialis anterior muscle of adult rats by in vivo electroporation.

97 ree questions: (1) whether PTEN knockdown in adult rats by nongenetic techniques enables CST regenera

98 r conditioning) or conditioned inhibition in adult rats by using serial section transmission electron

99 ssed in the somata and proximal dendrites of adult rat CA1 pyramidal cells.

100 Here we show that adult rats can learn to perceive otherwise invisible inf

101 sumption, showing that completely spinalized adult rats can recover unassisted hindlimb weight suppor

102 Adult rats can thus develop a novel cortical sensorimoto

103 Using membranes prepared from adult rat cardiac myocytes and fibroblasts, we found tha

104 cytes, human embryonic cardiac myocytes, and adult rat cardiac myocytes.

105 d by coexpression of CN-Aalpha/PKCepsilon in adult rat cardiac myofibroblasts (ARVFs) on a larger sca

106 4mtD3cpv, MitoCam) was expressed in cultured adult rat cardiomyocytes and the free mitochondrial calc

107 We cultured adult rat cardiomyocytes in a medium containing glucose

108 al expression of cMyBP-C(C10mut) in cultured adult rat cardiomyocytes was used to investigate protein

109 s motors selectively reduced IKur current in adult rat cardiomyocytes.

110 is channel complex in heterologous cells and adult rat cardiomyocytes.

111 lated transcript (CART) peptide depletion in adult rats, CART shRNAs or scrambled control shRNAs were

112 roligin 3 (NL3) or neuroligin 2 (NL2) in the adult rat cerebral cortex following in utero electropora

113 sion of CB2SH3- or CB2SH3+ in neurons of the adult rat cerebral cortex.

114 shing the set point for fibrotic activity in adult rat CFs and identify a key role for the modulation

115 We discovered that adult rat CFs express 190 GPCRs and that activation of p

116 lower and opioid effects are more evident in adult rats compared to early postnatal rats.

117 vivo recordings from the STN of anesthetized adult rats demonstrated that the spike firing rate was i

118 d that GABAergic responses in adolescent and adult rat DGCs are still depolarizing from rest.

119 AIE adult rats displayed heightened anxiety and decreased Ar

120 f KChIP1, KChIP2, KChIP3, DPP6, and DPP10 in adult rat dorsal root ganglion (DRG) and spinal cord by

121 and organs, enables siRNA to gain entry into adult rat dorsal root ganglion neurons in culture.

122 We now find that treatment of adult rat dorsal root ganglion neurons in vitro with LRP

123 t depletion of amphoterin mRNA from cultured adult rat DRG neurons attenuates neurite outgrowth, poin

124 s axonal regeneration, we plated dissociated adult rat DRGs transduced using AAV5-shRNA-fidgetin on a

125 right limb coupling of each limb pair in the adult rat during overground locomotion on a high-frictio

126 ood pressure and heart rate were obtained in adult rats during 4 weeks of CIHH exposure.

127 ) and dorsal striatum (DS) of adolescent and adult rats during a reward-motivated instrumental task.

128 ded daily from VTA neurons in adolescent and adult rats during learning and maintenance of a cued, re

129 the putative ventral-like hierarchy) of male adult rats, during the presentation of drifting gratings

130 e and Epac1 null E12.5 mouse heart explants, adult rat epicardial cells, and immortalized mouse embry

131 axonal translational machinery is present in adult rats, even when adult neurogenesis is blocked.

132 e demonstrate that VTA dopamine neurons from adult rats exhibit enhanced IPSCs after adolescent alcoh

133 ro brainstem slice preparation obtained from adult rats exposed either to air or CIHH for 4 weeks.

134 Experiments were performed on adult rats exposed to CIH for 10 days.

135 In contrast, LC neurons of adult rats exposed to repeated social stress were relati

136 Accordingly, in vitro recordings from adult rats exposed to WIN during adolescence demonstrate

137 t middle cerebral artery occlusion (MCAO) in adult rats, expression of FosDT and Fos was induced.

138 Older and younger adults rated faces high in trust cues similarly, but old

139 evaluated the role of PC1 in fibrogenesis in adult rat fibroblasts and myofibroblasts.

140 cantly reduced secondary injury pathology in adult rats following spinal contusion injury and LV-ChAB

141 of a continuous growth-promoting pathway in adult rats, formed by grafted Schwann cells overexpressi

142 Compared to young rats, adult rats had delayed functional recovery, whereas the

143 lear export in ventricular myocytes from the adult rat heart.

144 isolated neonatal murine cardiomyocytes and adult rat hearts (Langendorff preparation) mitochondrial

145 ed the splicing patterns in the neonatal and adult rat hearts.

146 on, and gene expression differ from those of adult rat hepatocytes.

147 ace with in vitro tissue simulant containing adult rat hippocampal NPCs (aNPCs) and their neuronal pr

148 roduction of long-term potentiation (LTP) in adult rat hippocampal slices that can account for one te

149 Here, we report that treatment of adult rat hippocampal slices with BDNF or with tetraethy

150 citatory post-synaptic potentials (EPSPs) in adult rat hippocampal slices.

151 from dentate gyrus granule cells (DGGCs) in adult rat hippocampal slices.

152 al circuit" between two substructures of the adult rat hippocampus consisting of principal cells wher

153 BDNF transcripts, occurs also in vivo in the adult rat hippocampus during BDNF-induced LTP.

154 rt we show that alpha-synuclein-accumulating adult rat hippocampus neural progenitors present aberran

155 zed synapses from postnatal day 15 (P15) and adult rat hippocampus that had undergone theta-burst sti

156 ization of CaMKII in CA1 stratum radiatum of adult rat hippocampus, by using immuno-electron microsco

157 e systemic HDACi administration in the young adult rat hippocampus.

158 on of MMP-2 and MMP-9 in early postnatal and adult rat hippocampus.

159 y in principal cells and interneurons of the adult rat hippocampus.

160 luences plasticity in the brain of young and adult rats; however, the effects were dependent of age a

161 The neonatal PCP treatment induced in the adult rat hyperlocomotion in response to amphetamine (Am

162 ound that populations of interneurons in the adult rat hypothalamus switched between dopamine and som

163 ecordings in prefrontal cortical slices from adult rats in which DISC1 function was reduced in vivo b

164 s dispensed to children decreased 13%, while adult rates increased 2%.

165 two different systems: zebrafish embryos and adult rats, indicating that this NKA-mediated regulatory

166 develop a robust preclinical model of PD in adult rats induced by the brain delivery of recombinant

167 Angiotensin II was infused into healthy adult rats, inducing chronic hypertension, and microRNA

168 even in sterile rat embryo islets, germ-free adult rat islets, and neogenic tubular complexes.

169 osomes accumulate in dendritic spines of the adult rat lateral amygdala (LA) during consolidation of

170 Adult rats learned a skilled forelimb grasping task and

171 ibrils and mitochondria, both collected from adult rat left ventricular myocytes.

172 In this study, we show that the adult rat liver harbors a small pool of endogenous mesen

173 al amygdala (MePD) are sexually dimorphic in adult rats: males have more astrocytes in the right MePD

174 endocannabinoid effects are more evident in adult rats (mature) compared to early postnatal (immatur

175 itical influence of the estrous cycle on the adult rat medial prefrontal cortex transcriptome resulti

176 Adult rat mesenteric tissues were harvested and cultured

177 nitric oxide synthase in the fat pad of the adult rat mesentery during inhibition of angiopoietin si

178 19) altered the size and organization of the adult rat midbrain dopaminergic (DA) populations.

179 cortex (OFC) and increase activity in NAC in adult rats, mimicking the imbalance during adolescence.

180 In dissociated adult rat mixed retinal cultures, dominant negative CASP

181 overy of diaphragm function after SCI in the adult rat model.

182 a drop in tobacco screen time for youth- and adult-rated movies (42.3% [95% CI, 24.1%-60.2%] and 85.4

183 ish below a tissue volume of ~7 mm(3) in the adult rat myocardium, revealing a fixed level of intrins

184 positioned to measure local [Ca(2+)]Cleft in adult rat myocytes.

185 w representation in forelimb amputated young adult rats (n=5) at 7 to 24 weeks after amputation.

186 ophysiological recordings in forelimb intact adult rats (n=8) to map the body representation in VPL w

187 ssure injection in both free solution and in adult rat neocortex in vivo, revealing IgG diffusion in

188 wann cells in vitro from freshly dissociated adult rat nerve.

189 for targeted genome modification in specific adult rat neurons using CRISPR-Cas9 technology.

190 , 6 weeks after forelimb amputation in young adult rats, new input from the shoulder becomes expresse

191 ia immunoreactivity was found throughout the adult rat NTS.

192 es long-distance optic nerve regeneration in adult rats of both sexes.

193 an electrical circuit in the hippocampus of adult rats of either sex consisting of principal cells w

194 Adult rat offspring that received low compared with high

195 striatal, and hippocampal subregions of male adult rat offspring.

196 s the HGF activation of cMet in neonatal and adult rat OL precursors.

197 Compared with those of young adult rats, old rats' V1 neurons exhibited significantly

198 Arc ensembles in adult rat olfactory bulb (OB) and anterior piriform cort

199 n in different brain areas of adolescent and adult rats on withdrawal days 1 and 14 showed time-depen

200 t of Set-beta to cellular membranes promoted adult rat optic nerve axon regeneration after injury in

201 ansplanted into either normal spinal cord of adult rats or the injury site in a dorsal column hemisec

202 After lateral fluid percussion injury in adult rats, oral treatment with EVT901 reduced neuronal

203 granule cells (GCs) generated in newborn and adult rats over extended periods of time.

204 cal properties of pyramidal neurons in young adult rats (P30-P60) exposed to ethanol inhalation durin

205 To control for age-dependent effects, adult rats (PD75-89) were exposed to identical experimen

206 Young adult rats performed a high repetition high force (HRHF)

207 kage study of a six-generational pedigree of adult rats phenotyped for one dimension of impulsivity,

208 We find that in adolescent (but not in adult) rats, preexposure to WIN results in cross-sensiti

209 owth and mitochondrial functions in cultured adult rat primary sensory neurons.

210 r to intravenous nicotine-associated cues in adult rats progressively increases or incubates after wi

211 owing the final adverse experience, when the adult rats received fear discrimination consisting of da

212 However, infusions of normal adult rat renal cells have been a successful therapy in

213 ic effector in situ We now show that EV from adult rat renal tubular cells significantly improved ren

214 e gel at 3 weeks after contusion SCI in male adult rats, resulted in significantly better locomotor p

215 Thy1 and HCN4, a cation channel subunit, in adult rat retina.

216 lectrode array recordings from postnatal and adult rat retinas, we demonstrated that adenosine signif

217 benefit the intrinsic ability of axotomized adult rat sensory neurons to undergo axonal regeneration

218 sponse (UPR) and cholesterol biosynthesis in adult rat sensory neurons.

219 However, adult rats showed sensitized fear learning, aberrant bas

220 etics during overground locomotion in female adult rats showed that locally rewired as well as compen

221 Electrophysiological measurements in adult rat slices confirmed this prediction and displayed

222 ed an immunohistochemical approach in normal adult rat small intestinal and ascending colonic tissue.

223 nd kindlin-1 on sensory axon regeneration in adult rat spinal cord after dorsal root crush and adeno-

224 this, we microinjected ferritin into intact adult rat spinal cords.

225 non-noxious tactile activity in the healthy adult rat spinal dorsal horn via activation of spinal 5-

226 er spinal transection and compare these with adult rats spinal transected 5 days postnatally, before

227 Adult rats spinal transected as neonates (NTX rats) at t

228 Trunk actions are important in adult rats spinalized as neonates (NTX rats) that walk a

229 vated plus maze in control adult rats and in adult rats subjected to early EE or to massage.

230 ches to investigate the mechanisms of GHS in adult rats subjected to neonatal colonic insult by intra

231 ression of endogenous alpha-synuclein in the adult rat substantia nigra by adeno-associated virus-med

232 ve sound experience has been demonstrated in adult rats, suggesting that it may be possible to design

233 at the ES in the seminiferous epithelium of adult rat testes, most notably at the apical ES at the S

234 calization in the seminiferous epithelium of adult rat testes.

235 components of the basement membrane (BM) in adult rat testes.

236 expression of sFRP1 is tightly regulated in adult rat testis to control spermatid adhesion and sperm

237 The steady-state protein level of Slc15a1 in adult rat testis was not affected by F5-peptide treatmen

238 ion, and synapse-related immunoreactivity of adult rat TH cells.

239 found a subpopulation of DCN neurons in the adult rat that express doublecortin, a plasticity-relate

240 Here, we show in young adult rats that 10 d of monaural conductive hearing loss

241 vHipp and BLA high-frequency stimulation in adult rats that received repeated injections of saline o

242 After CTX in adult rats, the chorda tympani nerve was labeled with bi

243 thanized at the age of one month (adolescent/adult rats), their brains were dissected out and coronal

244 to the atrioventricular node (AVN) region of adult rats to create complete AV block.

245 Compounds 2 and 5 were tested in adult rats to evaluate their long-term effects on dopami

246 or piriform cortex (aPC) must be engaged for adult rats to learn to discriminate highly similar odors

247 g mechanisms, we subjected 13 Sprague Dawley adult rats to unilateral 14 psi blast exposure to induce

248 xposure to induce targeted expansions in the adult rat tonotopic map and find that these bottom-up ch

249 owth responses to regulated NT-3 expression, adult rats underwent a C3 dorsal funiculus lesion.

250 Adult rats underwent complete tibial nerve transection f

251 n vitro, using the following three groups of adult rats: unexposed control (Ctrl); sound exposed with

252 (TBI) induced by lateral fluid percussion in adult rats, using 2 new ligands for PET: (18)F-GE-179 fo

253 2.22) are comparable with values for healthy adult rat ventricles (1.98 - 3.63).

254 nocolocalization experiments in neonatal and adult rat ventricular cardiomyocytes as well as murine h

255 In addition, cultured neonatal and adult rat ventricular cardiomyocytes were subjected to s

256 ected two ENTPD isoforms, ENTPD-1 and -2, in adult rat ventricular CFs.

257 try, and cell-based assays employing primary adult rat ventricular fibroblasts demonstrated that BRD4

258 alyzed contractility in the whole rat heart, adult rat ventricular myocytes (ARVMs), and myofibrils f

259 tutively bis-phosphorylated form in isolated adult rat ventricular myocytes and in mouse and rat vent

260 Using adult rat ventricular myocytes and mouse-derived cardiac

261 y and immunofluorescence in freshly isolated adult rat ventricular myocytes and those in short-term p

262 We investigated subpopulations of PLM in adult rat ventricular myocytes based on phosphorylation

263 Adult rat ventricular myocytes expressing wild-type SERC

264 In adult rat ventricular myocytes expressing wild-type SERC

265 Isolated adult rat ventricular myocytes were infected with wild-t

266 Primary adult rat ventricular myocytes were studied for morpholo

267 ndrial calcium concentration was measured in adult rat ventricular myocytes with a genetically target

268 Primary adult rat ventricular myocytes, adeno-associated virus (

269 e-induced hypertrophy in H9c2 cardiac cells, adult rat ventricular myocytes, and human induced plurip

270 Forster resonance energy transfer imaging of adult rat ventricular myocytes, surprisingly suggest tha

271 chondroitinase can restore plasticity in the adult rat visual cortex suggest a potential treatment fo

272 nd mutant SK2 channels were overexpressed in adult rat VMs, revealing serine-465 as the site that eli

273 r anaesthesia, the middle cerebral artery of adult rats was occluded for 60 min using the filament mo

274 Using adult rats we determined that pharmacological depletion

275 behavioral pharmacology and biochemistry in adult rats, we determined that betaAR activity during, b

276 Using multiple kinetic models in free-living adult rats, we first demonstrate that DHA uptake from th

277 In anaesthetized adult rats, we have found that Purkinje cells recorded f

278 In adult rats, we have identified a pathway linking the vlP

279 g ionic current blockers into the preBotC of adult rats, we identify the hyperpolarization-activated

280 al analyses in hippocampal slices from young adult rats, we show that E2 acutely suppresses inhibitio

281 Cohorts of alcohol-naive adult rats were cannulated in the central nucleus of amy

282 Adult rats were hemorrhaged to a pressure of 30 to 35 mm

283 Specifically, infant, juvenile and adult rats were presented with mild foot-shocks and thei

284 Fifty adult rats were randomly assigned to either (1) a sham g

285 Adult rats were trained in a staircase-reaching task and

286 entations in the anterior piriform cortex of adult rats when odor was associated with water reward ov

287 vioral neuroscience experiments, at least in adult rats where SWDs are prevalent.

288 ought to develop a surgical model of CAVB in adult rats, which could recapitulate structural remodeli

289 n the nTS bilaterally in anaesthetized naive adult rats, which increased fR and predictability of ven

290 days after permanent auditory deprivation in adult rats, which is partly reversed 90 days after deafn

291 dependent plasticity in the visual cortex of adult rats while recording single unit and population ac

292 In addition, animal studies have shown that adult rats who suffered febrile seizures during developm

293 Adult rats; wild-type/nicotinamide adenine dinucleotide

294 Pavlovian conditioned approach procedure in adult rats with a history of adolescent alcohol consumpt

295 g from individual thalamocortical neurons in adult rats with a recently developed automatic tracing t

296 but differentially, altered in neonatal and adult rats with BDV infection.

297 m awake unexposed controls and sound-exposed adult rats with behavioural evidence of tinnitus.

298 ral nervous system infection of neonatal and adult rats with Borna disease virus (BDV) results in neu

299 genesis, functional outcome, and survival in adult rats with brain lesions.

300 Adult rats with sciatic nerve crush were immediately and