ライフサイエンスコーパス: advanced

1 iquid electrolyte is directly visualized via advanced 3D chemical analysis.

2 Patients with advanced ACC were enrolled in a phase II study to evalua

3 Advanced adenoma detection rate was lower in the first F

4 od that patients with adenomas would develop advanced adenomas, a surrogate for CRC.

5 including male sex, NSAID coadministration, advanced age, and prior diagnoses contributing to drug r

6 to cellular senescence, which contributes to advanced age-related disorders, it is unclear how Kruppe

7 Current prediction models for advanced age-related macular degeneration (AMD) are base

8 atments that prevent or delay development to advanced age-related macular degeneration (AMD).

9 Mimicking the effect of advanced aging, genetic disruption of lysosomal function

10 ifferentially affect the risk for developing advanced alcohol-related liver disease.

11 cid groups for the development of a range of advanced all-polymer biosensors.

12 stage regions of interest reliably detected advanced Alzheimer's (Braak VI) pathology.

13 rophy, previously suggested as a new form of advanced AMD, and herein replicated.

14 ed with an increased risk for progression to advanced AMD, whereas diabetes and glaucoma were associa

15 ress of genetics, genomics, biochemical, and advanced analytical techniques to dissect the biosynthet

16 py for localized chondrosarcoma; for locally advanced and/or metastatic disease, no known effective s

17 I, 1.4 to 1.7; observed, 473; EAR, 18.2) for advanced- and early-stage cHL, respectively, compared wi

18 these combined therapies in the treatment of advanced atherosclerosis.

19 these combined therapies in the treatment of advanced atherosclerosis.

20 reg cells (SuperTreg cells) that can resolve advanced autoimmunity, with Brg1 re-expression in a mino

21 single-atom catalytic electrodes design for advanced battery systems is addressed.

22 Advanced battery systems with high energy density have a

23 erapy is effective in treating patients with advanced BC after resistance to TAM and aromatase inhibi

24 With new developments in the area of advanced biobased fibers, it would be possible to compet

25 ctors, but also new links of the plasmids to advanced bioinformatic tools.

26 Advanced bioink designs using various methods of dissipa

27 echniques are increasingly needed to support advanced biomedical information management and discovery

28 Advanced Bladder Cancer (BLCA) remains a clinical challe

29 or the development of prognostic markers for advanced BLCA.

30 AF and MEK has increased overall survival in advanced BRAF-mutant melanoma in both therapeutic and ad

31 trogen therapy was the standard treatment of advanced breast cancer for three decades until the disco

32 at least one previous line of treatment for advanced breast cancer or relapsed within 12 months of n

33 r winter wheat varieties from US Midwest and advanced breeding lines.

34 .01), and had lower odds of an FN finding of advanced cancer (odds ratio, 0.9 [95% CI: 0.5, 1.5]).

35 rmed a retrospective analysis of consecutive advanced cancer patient treated with PD-1/PD-L1 checkpoi

36 allel-group, randomised trial, patients with advanced cancer, aged at least 18 years, admitted to the

37 terventions for presently incurable forms of advanced cancer.

38 anticancer T cell responses in patients with advanced cancers.

39 xcellent properties and being selected as an advanced candidate.

40 ibrillation unresponsive to initial standard advanced cardiac life support (ACLS) treatment.

41 cardiopulmonary resuscitation, extension of advanced cardiopulmonary resuscitation beyond futility f

42 ues that this practice poses: termination of advanced cardiopulmonary resuscitation, extension of adv

43 of prostate cancer cells in a PLA device for advanced cell culture.

44 This advanced cellular construct based on a combinatorial nan

45 is appears to be the result of predominantly advanced cerebral amyloid angiopathy of the leptomeninge

46 intensification among patients with locally advanced cervical cancer (LACC) and paraaortic lymph nod

47 wed antitumour activity against recurrent or advanced cervical cancer.

48 (escalation, n = 12; expansion, n = 9) with advanced chondrosarcoma received ivosidenib (women, n =

49 c acid-enhanced MRI identified patients with advanced chronic liver disease who are at increased risk

50 Observational cohort of HF patients with advanced CKD (estimated glomerular filtration rate <30 m

51 decompensation: nonadvanced CLD, compensated advanced CLD (CACLD), and decompensated advanced CLD (DA

52 ated advanced CLD (CACLD), and decompensated advanced CLD (DACLD).

53 of PIK3CG was significantly associated with advanced clinical stages.

54 In patients with advanced CLL, a 5 x 10(8) dose of CART-19 may be more ef

55 on single-atom catalysts (Fe-N-C SACs) as an advanced co-reactant accelerator to directly reduce the

56 of 31 eyes from 31 consecutive patients with advanced Coats disease at an average age of 47.8 +/- 34.

57 to ablative procedures for the treatment of advanced Coats disease.

58 ecific cortical architecture does not hinder advanced cognitive skills.

59 h and clinical efforts, patients affected by advanced colorectal cancer (CRC) have still a poor progn

60 vels were significantly higher in NAFLD with advanced compared with earlier stages of liver fibrosis.

61 enhanced pharmacokinetic profile of the most advanced compounds, 30 and 27, led to significantly bett

62 d samples were analyzed using UHPLC-HRMS and advanced data analysis tools.

63 nerated with these tools, when combined with advanced data science approaches, can be used to generat

64 y, for trace, mild, moderate, confluent, and advanced destructive emphysema; P < .05).ConclusionDeep

65 sion), and physician-related factors (having advanced directives discussion) (p < 0.0001).

66 Results: Advanced disease (N1/M1) was observed in 35.3% of patien

67 ISUP grade was the superior predictor for advanced disease at diagnosis.

68 therapeutic options for muscle-invasive and advanced disease has expanded to include immunotherapy w

69 In this high-risk PCa cohort, we identified advanced disease in about one third at diagnosis.

70 y melanoma lesion will metastasize and cause advanced disease, but underlying mechanisms are not enti

71 LAMA2-CMD patients are often diagnosed after advanced disease, it is unclear if laminin-111 protein t

72 melanoma and now offer hope to patients with advanced disease.

73 ic failure at the site of implantation in an advanced disease.

74 d for prostate cancer staging, especially in advanced disease.

75 LC have brain metastases at the diagnosis of advanced disease.

76 it may serve as an ideal target to sensitize advanced DNA2-overexpressing cancers to current chemo- a

77 The National Kidney Registry (NKR) Advanced Donation Program enables living donors the oppo

78 These results lay the foundation for new advanced droplet techniques with transformative applicat

79 f agarose-based biomaterials in the realm of advanced drug delivery.

80 studies lay a foundation for developing more advanced dual Mcl-1/Bfl-1 inhibitors that have potential

81 th the Li anode and the LCO cathode, with an advanced electrolyte, are reported.

82 is at the heart of the functioning of modern advanced electronics; high electron mobility transistors

83 These results provide guidance for designing advanced EMI shielding materials but also highlight the

84 mutations are present at a high frequency in advanced endocrine-resistant ER(+) breast cancer.

85 Patients with advanced endometrial carcinoma have limited treatment op

86 Here, I use an advanced energy balance model to show that such an HZ wo

87 material developments draw inspiration from advanced energy management found in nature, such as the

88 l materials opens exciting opportunities for advanced energy technologies.

89 The results suggest that by employing advanced ensemble methods and using past information, it

90 Recent advanced EPR and Mn K-edge X-ray spectroscopy studies co

91 timodality therapy for patients with locally advanced esophageal carcinoma is recommended.

92 the data provide a strong rationale for the advanced evaluation of HSD17B12 inhibition as a promisin

93 ory of forests due to possession of multiple advanced features and likely relationship to subsequentl

94 ss, refraction, and (glare) visual acuity in advanced FECD.

95 abetes, the presence of NASH and concomitant advanced fibrosis (AF) was significantly associated with

96 AUCs for discriminating advanced fibrosis (CPA >10.3%) were 0.86 (95% CI: 0.76,

97 LCN2 in human alcoholic hepatitis (AH) with advanced fibrosis and portal hypertension and in experim

98 Conclusion: VCTE is a better biomarker of advanced fibrosis compared with APRI or FIB-4 in HBV/HIV

99 the gut microbiome as a novel biomarker for advanced fibrosis have only examined patients with nonal

100 h HFpEF and NAFLD also appeared to have more advanced fibrosis including cirrhosis suggesting a poten

101 els of non-alcoholic fatty liver disease and advanced fibrosis, as well as to detect non-alcoholic st

102 ons of cirrhosis, or liver-related death) or advanced fibrosis/non-alcoholic steatohepatitis (NASH) i

103 rescent proteins (RSFPs) serve as markers in advanced fluorescence imaging.

104 by D. gigas could share design features with advanced forms of animal communication.

105 Over 3 decades, gene therapy has advanced from a logical idea to becoming a clinical real

106 composition is now achievable for assembling advanced functional components.

107 trate that these polymers can be imbued with advanced functionalities.

108 sing ctDNA sequencing in 1,687 patients with advanced gastrointestinal (GI) cancer in SCRUM-Japan GOZ

109 95% CI, 2.6-6.2]; P < 0.001) and moderate to advanced glaucoma (mean, 34.7% and 38.5%, respectively;

110 Advanced glaucoma was defined by a cup-to-disc ratio of

111 integrating information from MAC and ONH in advanced glaucoma, suggesting that structural changes of

112 istics mentioned above and presentation with advanced glaucoma.

113 NFL thickness remains the most efficient for advanced glaucoma.

114 xtract on the formation of total fluorescent advanced glycation end products (AGEs) and Amadori adduc

115 ss-linking is glycation through formation of advanced glycation end products (AGEs).

116 kers of inflammatory mediators (receptor for advanced glycation end products [RAGE], MPO, uteroglobin

117 oncentrations of sRAGE (soluble receptor for advanced glycation end products) strongly associate with

118 ltration and albuminuria, and suppression of advanced glycation end-product signalling.

119 Advanced glycation end-products (AGEs) accumulate during

120 nce to quantify mast cells and expression of advanced glycosylation end-product specific receptor (AG

121 l failure of AR antagonists in patients with advanced HCC by evaluating potential resistance mechanis

122 Twenty-two percent of advanced HCC harbored potentially druggable genetic alte

123 ith complete tumor response in patients with advanced HCC treated by a specific MET inhibitor.

124 to compare safety profiles for patients with advanced HCC.

125 lth, for mortality, and for increased use of advanced healthcare services during and postdischarge al

126 ion have been reported in some patients with advanced heart failure (termed responders [R]) following

127 epair or replacement, and, in the setting of advanced heart failure, heart transplant and left ventri

128 e is known about the mutational landscape of advanced hepatocellular carcinoma (HCC), and predictive

129 portive care in the second-line treatment of advanced hepatocellular carcinoma over a lifetime horizo

130 in the Sorafenib versus Radioembolization in Advanced Hepatocellular Carcinoma trial.

131 tiple HER2-targeted therapies, patients with advanced HER2(+) breast cancer ultimately develop drug r

132 d, histologically or cytologically confirmed advanced HER2-negative breast cancer, an Eastern Coopera

133 tum-expectorating hospitalized patients with advanced HIV and access to both tests, concurrent testin

134 obably underestimates mitotic dysfunction in advanced human cancers.

135 rly iCCA or carefully selected patients with advanced iCCA after neoadjuvant therapy may benefit from

136 ylvania Health System and the Palliative and Advanced Illness Research Center.

137 We have employed advanced imaging flow cytometry (iFCM) to explore the ki

138 Advanced imaging for eye-related ED visits has escalated

139 Using advanced imaging methods and quasi-classical and fully q

140 Here, recent developments on the use of advanced imaging techniques for studying the structural

141 rdial infarction, need frequently arises for advanced imaging techniques to assist in differential di

142 lens formulas, intraoperative guidance, and advanced imaging technology and software have contribute

143 d were deeply phenotyped using metabolomics, advanced imaging, and clinical laboratory tests in addit

144 We combine fluid dynamics and advanced in situ transmission electron microscopy analys

145 afood species is time-consuming and requires advanced infrastructure.

146 e and survival and tumor response in locally advanced inoperable hepatocellular carcinoma treated wit

147 ed units characterize the crystal cargo, and Advanced-InSAR analysis highlights active deformation in

148 n (ITx) can be life-saving for patients with advanced intestinal failure experiencing complications o

149 limiting the number of compounds that can be advanced into clinical studies.

150 Two dmAbs, PGDM1400 and PGT121, were advanced into nonhuman primates for study.

151 was referred for decreased vision related to advanced keratopathy.

152 We randomly assigned 777 patients with advanced kidney disease and moderate or severe ischemia

153 for a national sample of 1000 patients with advanced kidney disease between 2004 and 2014 who were f

154 PEC strains have been associated with severe advanced kidney pathologies, such as cystitis and pyelon

155 both living donor liver transplantation and advanced laparoscopic liver surgery.

156 TLSs thus reveal an advanced level of self-organization and provide a powerf

157 the Lawrence Berkeley National Laboratory's Advanced Light Source (ALS) has been used in conjunction

158 by mass spectrometry (MS) has significantly advanced lipidomic studies.

159 d heart-liver transplantation resulting from advanced liver disease, including bridging fibrosis, cir

160 d hepatitis C (HCV) coinfected patients with advanced liver disease.

161 however serious AEs can occur in those with advanced liver disease.

162 ith anticoagulation (AC) are understudied in advanced liver disease.

163 with NAFLD, but the majority do not develop advanced liver disease: cirrhosis, hepatic decompensatio

164 FIB-4 >=2.67 defined patients with risk for advanced liver fibrosis.

165 ta have been analyzed, using a wide array of advanced Machine Learning techniques, to quantify how re

166 meters are probabilistically estimated using advanced Machine Learning tools.

167 d engineering, manufacturing, and the use of advanced materials due to its ability to produce objects

168 at have recently attracted great interest as advanced materials for energy-saving smart window applic

169 demonstrations and subsequent development of advanced materials for solid-state laser refrigeration.

170 s traditional bulky and low-value woods into advanced materials that have desired structures, durabil

171 to the reproductive decline associated with advanced maternal age.

172 be efficacious for the treatment of locally advanced/MBC for patients with bone, liver, lung, lymph

173 Administration-approved targeted therapy for advanced MCC.

174 of RSV and flu outbreaks to occurrence of 4 advanced medical outcomes (hospitalization, intensive ca

175 bination with PD-1 blockade in patients with advanced melanoma, non-small cell lung cancer, or bladde

176 pave a new avenue for scalable production of advanced mesoporous materials for various applications.

177 ial aconitase activity in the development of advanced metastatic prostate cancer and suggests that bl

178 rug discovery, we review key applications of advanced methods for sampling complex free-energy landsc

179 he overwhelming global aging, which requires advanced micro power sources with high energy density, l

180 argeting assay, structure-based mutants, and advanced microscopy.

181 with permanent functional deficit even after advanced microsurgical repair.

182 such as MRI, CT, and bone scan findings, but advanced molecular imaging techniques, especially prosta

183 e systems for prion propagation have greatly advanced molecular insights into prion biology, but tran

184 The utility of advanced MRI sequences such as diffusion-weighted imagin

185 ave been collected, dates of last frost have advanced much more rapidly than flowering dates.

186 Furthermore, application and integration of advanced multiplex techniques has been extremely limited

187 While newly advanced multiplexed FISH imaging offers possibilities f

188 Using advanced multivariate statistical analysis, we also show

189 to inspire the design and implementation of advanced nanobiosensor-based theranostic platforms takin

190 ls is an important determinant in developing advanced nanobiosensor-based theranostic platforms.

191 Advanced nanodevices require reliable nanocomponents whe

192 Patients with advanced NASH (NASH Clinical Research Network stage F3 o

193 y (P = .43).ConclusionThe detection rates of advanced neoplasia at CT colonography screening were gre

194 longitudinal joint model to estimate risk of advanced neoplasia at each subsequent examination after

195 mall adenomas at baseline have a low risk of advanced neoplasia over 10 years.

196 CT colonography, overall detection rates for advanced neoplasia were 2.7% and 5.0%, respectively (P <

197 structure-property relationships can lead to advanced networks with exceptional properties.

198 Patients with previously treated advanced NSCLC received nivolumab monotherapy (3 mg/kg e

199 Methods: Seventy-two patients with advanced NSCLC were recruited in a single-institution an

200 with MET-amplified, EGFR mutation-positive, advanced NSCLC, who had disease progression on a previou

201 readily downloadable from MISCAST to foster advanced offline analysis of missense variants by a wide

202 ientific CMOS (sCMOS) technology has greatly advanced optical microscopy for biomedical research with

203 rgeted systemic therapy may be used to treat advanced or metastatic cancer using the same indications

204 oint therapy in BRAF(V600) mutation-positive advanced or metastatic melanoma.

205 previous systemic treatment for progressive advanced or metastatic STS who had Eastern Cooperative O

206 patients aged 18 years or older with locally advanced or metastatic urothelial carcinoma, from 221 si

207 r cisplatin-ineligible patients with locally advanced or metastatic urothelial carcinoma.

208 advances in deep learning have tremendously advanced our ability to predict posture directly from vi

209 Recent research and guideline updates have advanced our understanding and management of ColdU.

210 This study advanced our understanding of how cutaneous plantar sens

211 These studies have greatly advanced our understanding of how noxious mechanical sti

212 iew, we discuss how genomics approaches have advanced our understanding of K. pneumoniae taxonomy, ec

213 hlight recent achievements that have greatly advanced our understanding of pollen tube attraction str

214 fective network-level resilience pattern has advanced our understanding of the coupling relationship

215 These discoveries advanced our understanding of the evolution of SNF in pl

216 interrogation of the HOXA9 regulome and has advanced our understanding of the molecular regulation n

217 Many studies have advanced our understanding of the pathways that contribu

218 The field of tissue engineering has advanced over the past decade, but the largest impact on

219 parameter for the design and operation of an advanced oxidation process (AOP) in water treatment.

220 Peroxymonosulfate (PMS)-based advanced oxidation processes generate highly reactive SO

221 on was exceeded in participants with locally advanced pancreatic cancer (17 months) and those with lo

222 rs +/- 10; 19 men), and 31 participants with advanced Parkinson disease (60 years +/- 9; 16 women).

223 Patients with advanced Parkinson's can be treated by deep brain stimul

224 he changes downstream of mTORC1 that lead to advanced pathologies in mouse might present new opportun

225 can be a promising drug delivery system for advanced PC.

226 e we show that IKBKE drives AR signalling in advanced PC.

227 become a standard therapy for patients with advanced PDAC and can be used to potentially downstage d

228 gether, our results highlight the ability of advanced peptide synthesis to achieve SAR tractability i

229 Advanced phenotyping of cardiovascular diseases has evol

230 CT02002455) was to evaluate the potential of advanced post-processing methods for (18)F-Fluciclovine

231 load, and burnout among the intensivists and advanced practice providers of established U.S. and Cana

232 urgeons, there was an increase by 27.36% for advanced practitioners.

233 rom primary adenocarcinoma, HT29 from a more advanced primary tumor and SW620 from lymph-node metasta

234 improving overall survival of patients with advanced prostate cancer that is incurable by surgery or

235 guideline on the optimal use of imaging for advanced prostate cancer.

236 y (ADT) is still a mainstay of treatment for advanced prostate cancer.

237 herapy remains a major challenge in treating advanced prostate cancer.

238 lines their potential for the realization of advanced quantum devices.

239 de are now standard of care in patients with advanced RCC.

240 ed interobserver agreement was observed with advanced reconstruction compared with standard 4-mm reco

241 The advanced reconstruction methods did not increase interob

242 organoid biobank from patients with locally advanced rectal cancer (LARC) treated with neoadjuvant c

243 ith overall recurrence, multiple recurrence, advanced recurrence, proximal recurrence, and distal ade

244 successful material applications, including advanced remediation and sensing technologies.

245 bnormally high blood levels in patients with advanced renal diseases.

246 Advanced sample clean-up procedures significantly impact

247 PDBe has developed an advanced search facility with ~100 data categories and s

248 pportunities that these devices have for the advanced sensing of pharmaceutical compounds toward safe

249 sh-Anderson glaucoma stages (mild, moderate, advanced, severe or blind) and death as health states.

250 ypothesize that metabolic derangement due to advanced shock in critically injured patients leads to t

251 n by offloading the hardware complexity into advanced signal processing techniques that are needed to

252 Progressions to advanced SM were observed in 2.9% of these patients.

253 ospective exploratory study, 8 patients with advanced solid malignancies and an indication for sorafe

254 iling enables genomic biomarker detection in advanced solid tumors.

255 lysis of patients with metastatic or locally advanced solid tumours harbouring oncogenic NTRK1, NTRK2

256 Cardiovascular alterations were monitored by advanced speckle tracking echocardiography, gene express

257 unclear if laminin-111 protein therapy at an advanced stage of the disease can have beneficial outcom

258 dence interval [CI]: 1.01, 3.5; P = .04) and advanced stage PDAC (10.8 months vs 18.0 months; HR, 2.1

259 as predictors of 5-year OS in patients with advanced-stage CRC.Keywords: Abdomen/GI, CT, Comparative

260 hed strategy for women with newly diagnosed, advanced-stage epithelial ovarian cancer.

261 was performed in 110 localized-stage and 556 advanced-stage FL patients.

262 cardial disease; (2) the patient had a known advanced-stage malignancy; (3) the patient already have

263 on-making in the management of patients with advanced-stage non-small-cell lung cancer (NSCLC) in lig

264 helial-to-mesenchymal transition features in advanced-stage patients, suggesting greater potential fo

265 Nevertheless, the majority of advanced-stage prostate cancer patients, including those

266 pokinetic nondilated phenotype, which in the advanced stages evolves into fibrosis without detectable

267 tween circulating PCSK9 and early as well as advanced stages of atherosclerosis in psoriasis.

268 es were more profound in early compared with advanced stages of fibrosis (P < 0.05 for both).

269 tages, n = 251; intermediate stages, n = 76; advanced stages, n = 144) who had received stage-adapted

270 CRC has high mortality when detected at advanced stages, yet it is also highly preventable.

271 Though advanced statistical analysis was used more commonly in

272 force-jump experiments, in combination with advanced statistical analysis, to show that octanoyl-CoA

273 high postoperative morbidity, requirement of advanced surgery, and pelvic recurrence after regrowth t

274 hese influential publications have immensely advanced surgical science over the decades and should se

275 responses, which may spread to produce more advanced systemic inflammation.

276 Advanced systemic mastocytosis (advSM) is characterized

277 However, those advanced technologies are severely limited by the effici

278 a novel, biomimetic, human bone platform for advanced testing of implants in vitro, and demonstrate t

279 Deep neural networks have advanced the field of detection and classification and a

280 espite whole tissue biopsy studies that have advanced the mechanistic understanding of AD, single cel

281 er have extended overall survival because of advanced therapies.

282 trates as a promising alternative to ILs for advanced thin-film devices.

283 e technologies, and how new discovery may be advanced through machine learning approaches.

284 186 references were identified, 4,162 papers advanced to abstract review, and 1,826 underwent full-te

285 Several of these inhibitors have advanced to clinical trials, both singly and in combinat

286 and the hard-soft acid-base (HSAB) theory is advanced to explain the observed reactivity trends.

287 ximines, this versatile functional group has advanced to implementation in several drug discovery pro

288 y trials testing viral vaccines that had not advanced to phase 2 before 2005, and the progress of eac

289 a compelling data package, 20 (AM-6494) was advanced to preclinical development.

290 Here, we present an advanced toolbox of cell cycle tag constructs in budding

291 Here, using advanced tools for real-time visualization of native YAP

292 yses, leaving a gap in how to integrate with advanced tools.

293 ependence occurs in approximately 15%-20% of advanced treatment-resistant prostate cancers, and this

294 stream of RB1, inactivated in SCLC and other advanced tumors, could have a broad impact on its treatm

295 l has shaped the field of cancer biology and advanced understanding of cancer pathophysiology.

296 e 800 treated seeds, 415 germinated and were advanced up to four (M4) generations by selfing.

297 vival, for patients with platinum-refractory advanced urothelial carcinoma.

298 ioned to harness such innovations due to its advanced use of electronic health-care records and the d

299 sease-free survival in patients with locally advanced UTUC.

300 harvested and utilized, it is believed that advanced wood materials will play a vital role in enabli