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1 ead) and the chromosomal locus iuc (encoding aerobactin).
2 tem but lacked the ability to produce or use aerobactin.
3 lly similar Fe-siderophore complexes like Fe-aerobactin.
4 amiliar traditional counterparts, e.g., iut (aerobactin; 57%) and sfaS (S fimbriae; 14%), thus possib
6 enes encoding the synthesis and transport of aerobactin, a hydroxamate siderophore associated with in
7 ent (DeltaiucA) derivatives established that aerobactin accounted for the overwhelming majority of in
9 he cytotoxic necrotizing factor 1 (cnf1) and aerobactin (aer) gene sequences to characterize the 15 O
11 and transport of the hydroxamate siderophore aerobactin are located within a 21-kb iron transport isl
13 with significant sequence similarity to the aerobactin biosynthesis enzymes IucB and IucC, respectiv
16 e absence of iuc (which encode hemolysin and aerobactin biosynthesis), nonagglutination of digalactos
18 la dysenteriae type 1 strains do not produce aerobactin but do contain sequences downstream of selC t
20 sulting in the generation of hvKP1DeltaiucA (aerobactin deficient), hvKP1DeltairoB (salmochelin defic
21 s hvKP1, A1142, and A1365 and their isogenic aerobactin-deficient (DeltaiucA) derivatives established
22 veals a gene, that we name aerE, encodes the aerobactin exporter, and LuxT is a transcriptional activ
23 ion sequences upstream and downstream of the aerobactin genes and an integrase gene that was nearly i
24 he same location in Shigella sonnei, but the aerobactin genes are not located within SHI-2 in Shigell
25 ression of the Shigella flexneri chromosomal aerobactin genes during growth of the bacterium within t
26 I and V, suggesting a common origin for the aerobactin genes in both S. flexneri and E. coli pColV.
29 h the relative activity being enterobactin > aerobactin > yersiniabactin > salmochelin, suggesting th
31 receptor, together with fhuCDB, encoding the aerobactin importer are sufficient to convert V. harveyi
32 to utilize the siderophores enterobactin and aerobactin, indicating that transport of these compounds
33 ream of selC and contains genes encoding the aerobactin iron acquisition siderophore system, colicin
36 l, MB-1), ferric hydroxamates (ferrichromes, aerobactin), mixed iron complexes (yersiniabactin, acine
37 for Shigella island 3, revealed a conserved aerobactin operon associated with a P4 prophage-like int
40 ts in siderophore receptors for salmochelin, aerobactin, or yersiniabactin displayed reduced fitness
41 of the proteins encoded by this operon, the aerobactin outer membrane receptor, Iut, was reduced in
42 co-culture, under iron-limiting conditions, aerobactin production allows V. fischeri ES114 to compet
45 rast, V. fischeri ES114 mutants incapable of aerobactin production lose in competition with V. harvey
46 on of digalactoside-coated beads, absence of aerobactin production, membership in serogroups O6 and O
49 re receptor mutants, including the DeltaiutA aerobactin receptor mutant and the DeltafyuA yersiniabac
55 he 63-kDa FrgA protein has homology with the aerobactin synthetases IucA and IucC of Escherichia coli
59 ochelin, suggesting that the contribution of aerobactin to virulence is dependent on both innate biol
61 he ferric siderophores desferrioxamine B and aerobactin were not readily bioavailable to Trichodesmiu