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1 ead) and the chromosomal locus iuc (encoding aerobactin).
2 tem but lacked the ability to produce or use aerobactin.
3 lly similar Fe-siderophore complexes like Fe-aerobactin.
4 amiliar traditional counterparts, e.g., iut (aerobactin; 57%) and sfaS (S fimbriae; 14%), thus possib
5                 We have also determined that aerobactin, a common bacterial siderophore involved in v
6 enes encoding the synthesis and transport of aerobactin, a hydroxamate siderophore associated with in
7 ent (DeltaiucA) derivatives established that aerobactin accounted for the overwhelming majority of in
8             These data strongly support that aerobactin accounts for increased siderophore production
9 he cytotoxic necrotizing factor 1 (cnf1) and aerobactin (aer) gene sequences to characterize the 15 O
10  Three are linked to genes for enterobactin, aerobactin, and yersiniabactin.
11 and transport of the hydroxamate siderophore aerobactin are located within a 21-kb iron transport isl
12 er, these data confirm and extend a role for aerobactin as a critical virulence factor for hvKP.
13  with significant sequence similarity to the aerobactin biosynthesis enzymes IucB and IucC, respectiv
14         In addition, one clone contained the aerobactin biosynthesis gene iucA.
15             Most convergent isolates contain aerobactin biosynthesis genes and produce more sideropho
16 e absence of iuc (which encode hemolysin and aerobactin biosynthesis), nonagglutination of digalactos
17 e, whose predicted product is similar to the aerobactin biosynthetic enzymes IucA and IucC.
18 la dysenteriae type 1 strains do not produce aerobactin but do contain sequences downstream of selC t
19 re sufficient to convert V. harveyi into an "aerobactin cheater."
20 sulting in the generation of hvKP1DeltaiucA (aerobactin deficient), hvKP1DeltairoB (salmochelin defic
21 s hvKP1, A1142, and A1365 and their isogenic aerobactin-deficient (DeltaiucA) derivatives established
22 veals a gene, that we name aerE, encodes the aerobactin exporter, and LuxT is a transcriptional activ
23 ion sequences upstream and downstream of the aerobactin genes and an integrase gene that was nearly i
24 he same location in Shigella sonnei, but the aerobactin genes are not located within SHI-2 in Shigell
25 ression of the Shigella flexneri chromosomal aerobactin genes during growth of the bacterium within t
26  I and V, suggesting a common origin for the aerobactin genes in both S. flexneri and E. coli pColV.
27                          The presence of the aerobactin genes on plasmids in E. coli pColV and Salmon
28                     The map locations of the aerobactin genes vary among closely related species.
29 h the relative activity being enterobactin > aerobactin > yersiniabactin > salmochelin, suggesting th
30          Virulence plasmid-encoded features (aerobactin, hypermucoidy) are observed at low-prevalence
31 receptor, together with fhuCDB, encoding the aerobactin importer are sufficient to convert V. harveyi
32 to utilize the siderophores enterobactin and aerobactin, indicating that transport of these compounds
33 ream of selC and contains genes encoding the aerobactin iron acquisition siderophore system, colicin
34                              The siderophore aerobactin is the dominant siderophore produced by hyper
35  salmochelin iro (odds ratio (OR): 29.8) and aerobactin iuc (OR: 14.1) loci.
36 l, MB-1), ferric hydroxamates (ferrichromes, aerobactin), mixed iron complexes (yersiniabactin, acine
37  for Shigella island 3, revealed a conserved aerobactin operon associated with a P4 prophage-like int
38                       The association of the aerobactin operon with phage genes and mobile elements a
39         These included sitABCD, genes of the aerobactin operon, hlyF, iss, genes of the salmochelin o
40 ts in siderophore receptors for salmochelin, aerobactin, or yersiniabactin displayed reduced fitness
41  of the proteins encoded by this operon, the aerobactin outer membrane receptor, Iut, was reduced in
42  co-culture, under iron-limiting conditions, aerobactin production allows V. fischeri ES114 to compet
43 clude Vibrio harveyi, which does not possess aerobactin production and uptake genes.
44                        Since it appears that aerobactin production is a defining trait of hvKP strain
45 rast, V. fischeri ES114 mutants incapable of aerobactin production lose in competition with V. harvey
46 on of digalactoside-coated beads, absence of aerobactin production, membership in serogroups O6 and O
47 , and LuxT is a transcriptional activator of aerobactin production.
48                 During intracellular growth, aerobactin promoter activity was repressed relative to t
49 re receptor mutants, including the DeltaiutA aerobactin receptor mutant and the DeltafyuA yersiniabac
50 ha (putative adhesin siderophore), and iutA (aerobactin receptor).
51           Introduction of iutA, encoding the aerobactin receptor, together with fhuCDB, encoding the
52                      Mutagenesis reveals the aerobactin siderophore as the inhibitor.
53                     Specific deletion of the aerobactin siderophore system and E. coli iro locus, whi
54                                 An S. boydii aerobactin synthesis mutant, 0-1392 iucB, was constructe
55 he 63-kDa FrgA protein has homology with the aerobactin synthetases IucA and IucC of Escherichia coli
56 tases (NIS synthetases) characterized by the aerobactin synthetases IucA and IucC.
57              These studies indicate that the aerobactin system is not highly expressed by bacteria wi
58                Interestingly, in contrast to aerobactin, the inability to produce enterobactin, salmo
59 ochelin, suggesting that the contribution of aerobactin to virulence is dependent on both innate biol
60                                     Further, aerobactin was the primary factor in conditioned medium
61 he ferric siderophores desferrioxamine B and aerobactin were not readily bioavailable to Trichodesmiu
62 bolite pathways (enterobactin, salmochelins, aerobactin, yersiniabactin, and colibactin).