ライフサイエンスコーパス: afferents

1 ptive axons mediating the stretch reflex (Ia afferents).

2 f optogenetic stimulation of thalamocortical afferents.

3 ion properties of identified primary tactile afferents.

4 ctions into zones, as they do for excitatory afferents.

5 iverse cell types, extracellular matrix, and afferents.

6 uning properties in remaining binocular dLGN afferents.

7 from the weight profiles of its presynaptic afferents.

8 l areas and is directly recipient of retinal afferents.

9 ked neuronal detection thresholds across all afferents.

10 and Y2Rs at the central terminals of primary afferents.

11 Cre mice enabled selective mapping of CRH(+) afferents.

12 eceptor content and peptidergic phenotype of afferents.

13 ive marker for proprioceptive muscle spindle afferents.

14 and dynamics of GABAergic and glutamatergic afferents.

15 ical sensitivity in somatosensory thin fibre afferents.

16 s of visceral pain) are the domain of nodose afferents.

17 he sympathetic nervous system via thin fibre afferents.

18 helial cells communicate directly with colon afferents.

19 cal stimuli to selectively activate Pacinian afferents.

20 that spares the central terminals of primary afferents.

21 arallel activation of both canal and otolith afferents.

22 s in the DG depend on the origin of incoming afferents.

23 some that appear selectively expressed in MS afferents.

24 abeling of either type I or type II cochlear afferents.

25 ed indiscriminately from among glutamatergic afferents.

26 ondary muscle spindles, and 24% as cutaneous afferents.

27 he sympathetic nervous system via thin fibre afferents.

28 aviors by integrating activity from numerous afferents.

29 tion distributed across three populations of afferents.

30 n effect not observed for M1-corticostriatal afferents.

31 in the dorsal root ganglion neurons of these afferents.

32 rite, a region targeted by cortical feedback afferents.

33 is required for function of these irregular afferents.

34 dorsal root ganglion (DRG) neurons of these afferents.

35 and running scales both SST and PV synaptic afferents.

36 ent neurons excites calyx and dimorphic (CD) afferents.

37 ires CB1 receptors on cortical glutamatergic afferents.

38 temporally precise activation of vestibular afferents.

39 ed by functional rapidly adapting trigeminal afferents.

40 receive direct sensory input from peripheral afferents.

41 synapses with presynaptic entorhinal cortex afferents.

42 antly altered cortical modulation of primary afferents.

43 formation about its long-range efferents and afferents.

44 gonadal hormones to sex differences in vHPC afferents.

45 and subcortical regions with known striatal afferents.

46 alance of entorhinal versus intrahippocampal afferents.

47 ase induced by activation of thalamostriatal afferents.

48 homeostatic regulation and pain are found in afferents across all ganglia types, suggesting that cons

49 ChINs is attenuated by dopaminergic midbrain afferents acting presynaptically on D2 receptors.

50 d PAS require activity in (higher threshold) afferents activated by the muscle twitch evoked by elect

51 ism, and that opioid peptides suppress these afferents' activity.

52 is the principal target of the serotonergic afferents along with the limbic system, and it was shown

53 Vestibular afferents also responded to electrical stimuli up to 300

54 d with respect to studies of the mouse vagal afferents, an area of research of increasing popularity.

55 electrical vestibular stimuli on vestibular afferents and a current model of central vestibular proc

56 nked to an increase in resting discharges of afferents and a decrease in their sensitivities.

57 ional in the peripheral terminals of colonic afferents and activation of these receptors via endogeno

58 relationship between striatal glutamatergic afferents and behavioral reinforcement is not well under

59 3/MrgD-expressing nociceptive/pruritoceptive afferents and C-low threshold mechanoreceptors.

60 appa-opioid receptors (KORs) on dopaminergic afferents and can negatively regulate dopamine release.

61 es between the extra-striatal D2R-expressing afferents and D1R-expressing MSNs (D2->D1), as compared

62 tory connections between perforant path (PP) afferents and dentate granule cells (GCs), a circuit inv

63 helium, intravesical K(+) sensitizes bladder afferents and enhances their response to distension.

64 re sensation and pain are mediated by spinal afferents and fear and anxiety (the affective aspects of

65 ive feedback from Group Ia/II muscle spindle afferents and Group Ib Golgi tendon afferents is critica

66 rogen receptor-expressing neurons in primary afferents and in superficial dorsal horn neurons, there

67 s extremities, it contained a mixed of vagal afferents and postganglionic sympathetic neurons.

68 ses were observed close to primary olfactory afferents and projection neurons.

69 of sensation due to degeneration of injured afferents and reduced incidence of post-injury hypersens

70 , we used mouse brain slices to stimulate DG afferents and simultaneously record DG granule cells (GC

71 We found that both the spared primary afferents and somatosensory corticospinal efferents spro

72 source of highly opioid-sensitive GABAergic afferents and support the idea that different GABAergic

73 gonists decrease the excitability of colonic afferents and suppress visceral nociception.

74 erred combinations of the number of thalamic afferents and the number of synapses per afferent that m

75 responses by stimulating cardiac sympathetic afferents and these CSR responses are modulated by endog

76 titative sensory testing including C-tactile afferents, and pain-related evoked potentials.

77 these ensembles are driven by primary bulbar afferents, and shaped by intracortical recurrent connect

78 sponses through activation of cardiac spinal afferents, and that endogenous opioids suppress the P2X

79 such alignment was observed only for Merkel afferents; angular tuning of the other afferent types sh

80 We have shown that functional muscle spindle afferents are absent in the upper and lower limbs in HSA

81 Given that functional muscle spindle afferents are also absent in the upper limb, we assessed

82 nner hair cell, whereas unmyelinated type II afferents are fewer in number and receive input from man

83 CeA afferents are GABAergic (express Slc32a1/Vgat) and are d

84 PVH afferents are glutamatergic (express Slc17a6/Vglut2) and

85 mp experiments demonstrate that serotonergic afferents are largely excitatory for mitral cells (MCs)

86 Type I afferents are myelinated, larger diameter neurons that s

87 In the face, cutaneous and muscle afferents are segregated in the trigeminal and facial ne

88 Delta(9)-THC through modulation of glutamate afferents arising from corticolimbic brain areas implica

89 viduals with HSAN III rely more on cutaneous afferents around the elbow.

90 ed similar distributions of villus and crypt afferents as control mice, suggesting surgery did not co

91 timulation of mossy fiber and climbing fiber afferents as CS and US, while alternating between short

92 tin receptors (LepRs) are expressed by vagal afferents as well as by a population of NTS neurons.

93 stablish the resting excitability of colonic afferents as well as the behavioural response to noxious

94 presents synaptic terminations of projecting afferents, at least in part, including nociceptive A-del

95 For example, inhibitors of vagal afferents-baclofen could be beneficial in patients.

96 ed subclasses of spinal afferents, how these afferents become sensitized in highly dynamic signaling

97 By contrast, more regular afferents better discriminated between different static

98 udies support the idea that these evaluative afferents bidirectionally modulate VTA dopamine neurons

99 nomia, do not have functional muscle spindle afferents but do have essentially normal cutaneous mecha

100 rats, and this reflex is dependent on vagal afferents but is not due to steady state blood pressure

101 of similarity in prefrontal and hippocampal afferents but some differences in afferent connectivity

102 quency signals encoded by primary vestibular afferents, but undergo low-pass filtering at intermediat

103 sual cortical topography that sorts thalamic afferents by eye input and stimulus polarity along ortho

104 sual cortical topography that sorts thalamic afferents by eye input and stimulus polarity, and then m

105 d activation and sensitisation of trigeminal afferents by meningeal inflammatory stimuli and upstream

106 lls influence discharge rates in their calyx afferents by modulating the potassium concentration in t

107 l of head rotation encoded by the vestibular afferents can cause perceptions of both linear and angul

108 that low-frequency spike trains in Pacinian afferents can readily induce a vibratory percept with th

109 In vestibular cerebellum, primary afferents carry signals from single vestibular end organ

110 phalon, whereas >90% of mesencephalic D1-MSN afferents collateralized to the ventral pallidum.

111 How the organization of cholinergic afferents confers this level of precision remains unknow

112 s ON UBCs, but not OFF UBCs, while secondary afferents contact both subtypes.

113 We show that a specialized subset of primary afferents contacts ON UBCs, but not OFF UBCs, while seco

114 ever, it is unknown how and when distinct PL afferents contribute to different associative components

115 Specific, peripheral C-tactile afferents contribute to the perception of tactile pleasu

116 the pelvic nerve, which contain dichotomized afferents, could be an important mechanism contributing

117 the pelvic nerve, which contain dichotomized afferents, could underlie storage LUTS in symptomatic BP

118 Compared with villus afferents, crypt innervation exhibited a muted proximal-

119 There were clusters of colon and bladder afferents, defined by mRNA profiling, that localized to

120 strated synaptic connections between primary afferents, descending cortical inputs, and inhibitory in

121 suggest that a gradient of Fzd3 in inner ear afferents directs projections to the correct dorsoventra

122 Cells in these nuclei, as well as their afferents, display a large number of striking physiologi

123 lts from the precise arrangement of thalamic afferents during cortical development.

124 ourse of transient IFRs in muscle spindle Ia afferents during stretch (i.e., lengthening) of passive

125 metry to record in vivo activity in vHIP-NAc afferents during tests of depressive- and anxiety-like b

126 rmined projection-specific activation of OFC afferents during the relapse test by using Fos plus the

127 g of afferent firing, particularly irregular afferents, efferents adjust neural activity sensitive to

128 Here, we demonstrate that vestibular primary afferents encode high-frequency stimuli through frequenc

129 mine signals both in vivo and in vitro These afferents engage cholinergic interneurons, which drive d

130 rent temporal characteristics and that vagal afferents enhance parasympathetic and reduce sympathetic

131 facial muscles are predominantly peptidergic afferents enriched with TRPV1.

132 Low-threshold cutaneous afferents evoke a GABA(A)-receptor-dependent form of PSI

133 most responsive region to cocaine among LHb afferents examined and that single cocaine infusions ind

134 All afferents exhibited strong "angular tuning," i.e., their

135 Furthermore, colon and bladder afferents expressed genes at similar levels, although di

136 t in insulin-resistant animals, portal vagal afferents failed to inhibit their spiking activity durin

137 C-tactile afferents form a distinct channel that encodes pleasant

138 ound at all anatomic levels, suggesting that afferents from different portions of the neuraxis have o

139 omprising many glomerular modules defined by afferents from different receptor neuron subtypes.

140 ervated from the LHbL, whereas pVTA receives afferents from LHbM and LHbL.

141 fferentially in layers II/III and V striatal afferents from motor cortex and that cortical BDNF is es

142 rotonergic and corticospinal tract axons and afferents from muscle and skin.

143 kely mediated by stimulation of MORs in GABA afferents from other brain regions than in VTA GABA neur

144 Moreover, the maturation of mossy fiber afferents from pontine neurons and the expression of the

145 sly to suppress representation of excitatory afferents from PPG neurons, thereby diminishing the impa

146 ry tract reflexes are mediated by peripheral afferents from the bladder (primarily in the pelvic nerv

147 nal cord horn that receives visceral sensory afferents from the bladder and distal colon, a pathologi

148 e the striatum receives extensive excitatory afferents from the cerebral cortex, the influence of dif

149 e solitary tract (NTS) is activated by vagal afferents from the gastrointestinal tract, which promote

150 he ascending connections of the nTTD and the afferents from the syrinx to the trigeminal sensory colu

151 In rodents, nucleus accumbens (NAc) afferents from the ventral hippocampus (vHIP) are implic

152 synergistic model, we highlight dopaminergic afferents from the ventral tegmental area to nucleus acc

153 mouse behavioral models, that glutamatergic afferents from the ventral tegmental area to the dorsal

154 sed to identify functional clusters of colon afferents from thoracolumbar (TL), lumbosacral (LS), and

155 gle vestibular end organs, whereas secondary afferents from vestibular nucleus carry integrated signa

156 A total of 132 colon afferents (from NG, TL, and LS ganglia) and 128 bladder

157 from NG, TL, and LS ganglia) and 128 bladder afferents (from TL and LS ganglia) were analyzed.

158 triggered by transmitters released by vagal afferents, glutamate acting at AMPA receptors and 5-HT a

159 le the presence of GABA receptors on primary afferents has been well described, most functional analy

160 ntestine, whereas nutrient-activated mucosal afferents have no effect.

161 nervated by specialized subclasses of spinal afferents, how these afferents become sensitized in high

162 rtex and other brain regions beyond the core afferents identified previously.

163 ks, astrocytes control signals from distinct afferents in a circuit-specific manner, but whether this

164 f two distinct modes of PSI of somatosensory afferents in adolescence and throughout adulthood.

165 d aberrant central projections of vestibular afferents in both cases.

166 Nociceptive afferents in craniofacial muscles are predominantly pept

167 ptogenetic stimulation of S1-corticostriatal afferents in ex vivo recordings produced larger postsyna

168 on directly by recording from single otolith afferents in monkeys during naturalistic translational s

169 Aergic PPT cells, or excitation of GABAergic afferents in PPT, abolish signaled active avoidance.

170 e used optogenetics to stimulate cholinergic afferents in prefrontal cortex brain slices from compoun

171 Central sprouting of nociceptive afferents in response to neural injury enhances excitabi

172 ng in vivo two-photon Ca(2+) imaging of dLGN afferents in superficial layers of V1 in female and male

173 Quantitative assessment of TRPV1-lineage afferents in the epidermis of the hind paws of the repor

174 through activation of vagal and sympathetic afferents in the heart through the release of ischemic m

175 single- and multi-unit activity from primary afferents in the lumbar DRG using non-penetrating electr

176 a long sought-after molecular atlas of vagal afferents in the mouse.

177 afferent cross-sensitization through primary afferents in the pelvic nerve, which contain dichotomize

178 Stimulation of low threshold afferents in the trigeminal nerve produced a clear SAI (

179 Representing highly relevant afferents in three-dimensional body-part-models might fa

180 Low-frequency stimulation of PAG afferents in vitro unexpectedly causes long-term potenti

181 ate they project, as with other unmyelinated afferents, in lamina I-spinothalamic pathways.

182 aracteristics of mammalian muscle spindle Ia afferents - including movement history dependence, and n

183 d neuroplastic changes in trigeminal sensory afferents, increasing calcitonin gene-related peptide ex

184 ceived direct input from solitary tract (ST) afferents, indicating that they form part of a feedforwa

185 cal vestibular stimuli encoded by vestibular afferents induce a net signal of linear acceleration, ro

186 Stimulation of trigeminal afferents induced short-latency (SAI) but not long-laten

187 abeling from the colon showed that NG and TL afferents innervate proximal and distal regions of the c

188 rsal root ganglion neurons with dichotomized afferents innervating both prostate and bladder.

189 Within trigeminal ganglia, afferents innervating craniofacial muscles interact with

190 duction of mechanical information in sensory afferents innervating the skin and viscera.

191 Vagal afferents innervating the small intestinal mucosa regula

192 rom diverse sources, including multiple GABA afferents, interneurons, and projection neurons.

193 origin of the cell bodies of uterine spinal afferents is clear, the identity of their sensory ending

194 reinnervation of muscle by motor and sensory afferents is completed in the periphery.

195 spindle afferents and Group Ib Golgi tendon afferents is critical for the normal execution of most m

196 hat alpha-SYN present in dopaminergic nigral afferents is essential for the normal cycling and mainte

197 erent-mediated slow excitation of vestibular afferents is mediated by muscarinic acetylcholine recept

198 rly considering new evidence that overlap of afferents is substantial.

199 n rodents, the thalamic target of these TGCs afferents is the caudal division of the pulvinar complex

200 location of the nerve cell bodies of spinal afferents is well known to reside in dorsal root ganglia

201 (A)Rs) or NMDA receptors (NMDARs) in primary afferents leads to tactile hypersensitivity across skin

202 During high-frequency stimulation of vagal afferents, leptin increased the size of NMDAR-mediated c

203 etics, it was confirmed that basal forebrain afferents mediate IPSCs on granule and deep short axon c

204 kers of postganglionic sympathetic and vagal afferents neurons.

205 In myelinated afferents, nodal length increased postoperatively [pre:

206 togenetic neuromodulation of bladder sensory afferents normalizes bladder function.

207 the mechanical responsiveness of thin fibre afferents not only at dorsal root ganglion, but also at

208 cord and central targets of primary sensory afferents (nucleus of the solitary tract, spinal trigemi

209 Also, cochlear afferents of Fzd3 mutant mice lack the orderly topologic

210 push-pull" encoding of stimulus direction by afferents of opposite polarity is disrupted while still

211 ther the elimination of unmyelinated primary afferents of the adjacent uninjured nerves (L3 and L4) w

212 nsitive fibers were also detected in lingual afferents of the control group, that were significantly

213 Primary afferents of the haltere encode its oscillation frequenc

214 Mechanosensory afferents of the massive array of chordotonal organs (Jo

215 es that have systematically investigated the afferents of the RE have only been performed in rats.

216 stal regions of the colon, whereas 98% of LS afferents only project to distal regions.

217 tatory drive from parabrachial nucleus (PBN) afferents onto CRF neurons.

218 Stimulation of glutamatergic afferents or glutamate application induced sodium transi

219 ether hyperalgesic priming in nonpeptidergic afferents or repeated acid injections also affect cranio

220 Chemogenetic silencing of TRPV1-expressing afferents or rostral ventromedial medulla neurons attenu

221 Stimulating either mCbN afferents or TH neurons augments IPSCs and suppresses EP

222 on thresholds (p < 0.01), impaired C-tactile afferents (p < 0.05), and reduced amplitudes (p < 0.001)

223 ally isolated from extrasubicular excitatory afferents, pharmacologically disinhibited subicular slic

224 ar afferent subtypes, whereas small-diameter afferents predominantly evoke an NMDA-receptor-dependent

225 ptogenetic stimulation of S1-corticostriatal afferents produced task-specific behavioral inhibition,

226 Optogenetic stimulation of M1 afferents produced the opposite behavioral effect.

227 Craniofacial muscle afferents project to a wide area within the trigeminal n

228 are active during motor behavior to suppress afferents projecting to the brain [7-12].

229 cognate prolactin receptor (PRLR) in primary afferents promotes nociceptor sensitization and pain in

230 Electrical stimulation of low-threshold afferents proximal to the axotomized L5 spinal nerve att

231 periphery reshapes these circuits as soon as afferents reach the cortex.

232 es of primary otolith and semicircular canal afferents remain intact during both active and passive s

233 esults in a profound inhibition of irregular afferents' resting discharges, rendering them inadequate

234 ants/pollutants activates airway nociceptive afferents resulting in reflex bradycardia in healthy ani

235 inflamed neurons as well as nearby uninjured afferents, resulting in hyperalgesia and ectopic pain or

236 nd electrical stimulation of corticostriatal afferents revealed that histamine, acting at H(3) recept

237 Double labeling of JO and ocellar afferents revealed that input from the JO and visual inf

238 Anterograde double staining of the antennal afferents revealed that JO receptor neurons project to s

239 raphy.SIGNIFICANCE STATEMENT Thalamocortical afferents segregate in primary visual cortex by eye inpu

240 avoidance gated by nigral and other synaptic afferents.SIGNIFICANCE STATEMENT When a harmful situatio

241 ntral projections of peripherally injured Ia afferents, suggesting a possible causal relationship bet

242 and receive different proportions of certain afferents, suggesting that while SIF motoneurons would p

243 ll understood, inhibition of bladder sensory afferents temporarily relieves pain.

244 rate (~100-150 Hz) and at higher frequencies afferents tended to phase-lock to the vestibular stimulu

245 While basal forebrain afferents terminate in the infragranular layers of V1, a

246 he PVN, selective optogenetic stimulation of afferents that arise from these lamina terminalis AT1aR

247 part, from increased excitability of primary afferents that innervate the colon.

248 n of changes in glucose inflow through vagal afferents that require an activated glucagon-like peptid

249 cation of peripheral nerve endings of spinal afferents that transduce sensory stimuli into action pot

250 y, rather than structural changes in primary afferents, that are responsible for alleviating hypersen

251 Outside the volume targeted by TC afferents, the resulting postsynaptic LFP signals were f

252 muscle stretch) also activate muscle spindle afferents, the selective role of GTOs remains uncertain.

253 were observed between primary and secondary afferents, their synapses, and the UBCs they contact.

254 acellular ATP stimulates cardiac sympathetic afferents through P2 receptor-mediated mechanism, and th

255 pathways required for targeting Merkel-cell afferents to discrete mechanosensory compartments.

256 ergic transmission at D1R- or D2R-expressing afferents to DMS MSNs.

257 ggest 5-HT exerts a direct effect on bladder afferents to enhance signalling.

258 y life injury weakens the ability of sensory afferents to evoke feedforward inhibition of adult spina

259 o examined the transmitter phenotype of LDTg afferents to IP by combining retrograde tracing with imm

260 neurons and potentially sensitizes group IV afferents to mechanical stimuli at the muscle tissue lev

261 emniscal) and matrix (nonlemniscal) thalamic afferents to MMN generation.

262 Thus, a decrease in inhibitory afferents to MNTB neurons should lead to greater inhibit

263 a detailed functional assessment of the AON afferents to piriform in male and female C57Bl/6J mice.

264 ation of either glutamatergic or cholinergic afferents to probe the relative roles of different signa

265 PCP pathway plays a role in guiding cochlear afferents to the cochlear nuclei in the hindbrain, consi

266 Glutamatergic afferents to the NAc direct MSN output by recruiting fee

267 While molecular guidance of sensory afferents to the periphery has been well studied, molecu

268 LHb afferents to the pVTA are distinct from those to the RMT

269 ds on coordinated activity of three distinct afferents to the rostromedial tegmental nucleus (RMTg) a

270 Different afferents to the striatum can trigger dopamine signals,

271 relimbic (PrL) and infralimbic (IL) cortical afferents to the striatum triggers an increase in extrac

272 enetic stimulation of cortical glutamatergic afferents to the striatum triggers dopamine signals both

273 espective contribution of distinct prelimbic afferents to the temporal and contextual components of m

274 Afferents to the ventral pallidum arise from both D1- an

275 vioral and optogenetic methods to identify 2 afferents to the ventral tegmental area (VTA) that serve

276 py were used to determine NPY-immunoreactive afferents to the VTA.

277 Group III/IV muscle afferents transduce nociceptive signals and modulate exe

278 indicate that irregular and regular otolith afferents use different strategies to encode naturalisti

279 Profiling of TL and LS bladder afferents was also performed.

280 responses and the activation of nociceptive afferents, we analyzed BP and HR responses to electrical

281 cally-restricted rabies virus tracing of OPC afferents, we identified extensive afferent synaptic inp

282 a stochastic model of repetitive activity in afferents, we largely explain the main features of GVS-e

283 In addition, transcriptionally, NG colon afferents were almost completely segregated from colon T

284 Visceral afferents were back-labeled using retrograde tracers inj

285 Vagal afferents were found to be organized into 24 subtypes, r

286 function of these AChRs, single unit sensory afferents were recorded from an isolated mouse extensor

287 CRH(+) NAc afferents were selectively enriched in NAc-projecting br

288 ivity in low threshold, presumably cutaneous afferents, whereas LAI and PAS require activity in (high

289 multitude of other cortical and subcortical afferents, which likely modulate its function.

290 ined how GoCs integrate inputs from specific afferents, which vary in density to regulate GrC populat

291 tion and is especially important for primary afferents whose spikes must cross a T-junction to reach

292 urons integrate sensory input from cutaneous afferents with descending signals from the brain to prom

293 Otolith afferents with higher intrinsic variability transmitted

294 combining the influence of EVS on vestibular afferents with known mechanisms of vestibular processing

295 We find that afferents with similar or differing preferred directions

296 from prehearing mice while stimulating MNTB afferents with stimulation patterns that mimicked those

297 central termination profiles of nociceptive afferents with synaptoporin, an isoform of synaptophysin

298 Treatment of muscle spindle afferents with the high-affinity choline transporter ant

299 ron microscopic analysis of the two Meissner afferents within the corpuscle supports a model in which

300 sistent with the preponderance of cerebellar afferents within the pons, we observed a significant pos