ライフサイエンスコーパス: afflict

1 e systems with 20% of the world's population afflicted.

2 this pinnacle of clinical research is itself afflicted.

3 rain on the caregivers and families of those afflicted.

4 most common inherited peripheral neuropathy, afflicting 1 in every 2500 Americans.

5 Iron deficiency anemia afflicts 1 in 3 individuals, mostly women and children w

6 opathy of the peripheral nervous system that afflicts ~1:2500 people.

7 ce in major depressive disorder (MDD), which afflicts ~14%-20% of individuals.

8 d stunting is a major public health problem, afflicting 155 million people worldwide.

9 nemia, or low blood hemoglobin (Hgb) levels, afflicts 2 billion people worldwide.

10 ing major depressive disorder-a disease that afflicts ~20% of the world's population.

11 Ovarian cancer is a deadly disease that afflicts ~22,000 women per year in the United States, an

12 ral therapy (cART), neurocognitive disorders afflict 30-50% of HIV-infected individuals and synaptode

13 n cardiac death (SCD) is a devastating event afflicting 350 000 Americans annually despite the availa

14 Epilepsy is a neurological disorder afflicting ~65 million people worldwide.

15 Asthma is a common disorder that in 2009 afflicted 8.2% of adults and children, 24.6 million pers

16 ys.IMPORTANCE Herpes simplex virus 1 (HSV-1) afflicts 80% of the population worldwide, causing variou

17 Afflicting ~80% of women, and symptomatic in 25%, UFs br

18 ing the performance-monitoring deficits that afflict a broad range of populations.

19 hundreds of misglycosylated products, which afflict a myriad of processes, including cell signaling,

20 cribe the vascular and thromboembolic events afflicting a series of 40 patients diagnosed with neoehr

21 ) is a common neurodevelopmental disturbance afflicting a variety of functions.

22 Severe asthma (SA) afflicts a heterogeneous group of asthma patients who ex

23 Postoperative cognitive dysfunction, POCD, afflicts a large number of elderly surgical patients fol

24 ing our understanding of this condition that afflicts a significant proportion of the global populati

25 Hemophilia is a bleeding disorder that afflicts about 1 in 5000 males.

26 tative or obstructive symptoms that commonly afflict aging population.

27 Lymphomas afflict all age groups of people, with certain types dem

28 lying neurocognitive impairment continues to afflict almost 50% of infected individuals.

29 Paralytic polio once afflicted almost half a million children each year.

30 s for detecting additional risk SNPs for the afflicting and closely related disorders, but not for di

31 g Brucella IgG antibodies in milk samples of afflicted animals.

32 It also afflicts animals, including dogs, horses, and sheep.

33 peutics to treat the millions of individuals afflicted annually with diseases caused by picornaviruse

34 l and head and neck cancers are predicted to afflict another 700,000 men and women over this time per

35 fatty liver disease (NAFLD) is estimated to afflict approximately 1 billion individuals worldwide.

36 a constellation of 17 tropical diseases that afflict approximately one in six individuals on the plan

37 the parasitic witchweeds (Striga spp.) that afflict approximately one quarter of sub-Saharan African

38 (GWI), a chronic multisymptom health problem afflicting approximately 25% of veterans who served in t

39 Afflicting approximately 8 million people in Latin Ameri

40 Binge eating afflicts approximately 5% of US adults, though effective

41 osis of hyperbilirubinemia (a condition that afflicts approximately 60% of full-term and 80% of pre-t

42 However, nearly 50% of those afflicted are considered nonresponsive to available trea

43 The majority of those afflicted are women.

44 troke, where the proton concentration in the afflicted area can increase by an order of magnitude.

45 tered sinusoidal endothelium adjacent to the afflicted area, paving approximately 200 microm abutting

46 Some afflicted areas remained depopulated for long periods, w

47 DMD is a debilitating X-linked disease that afflicts as many as 1 in 3,500 boys.

48 Acute graft-versus-host disease (GVHD) afflicts as much as 80% of all patients who receive an u

49 tes of mismatch and deletion errors that can afflict barcodes.

50 ion (EMT) has been proposed as one mechanism afflicting barrier in asthma.

51 Severe obesity afflicts between 4% and 6% of all youth in the United St

52 ates, the hereditary form disproportionately afflicts black Americans, who when compared with whites

53 High-grade gliomas (HGG) afflict both children and adults and respond poorly to c

54 ystrophy (FSHD), the most prevalent myopathy afflicting both children and adults, is predominantly as

55 Eosinophilic esophagitis (EoE) afflicts both children and adults.

56 , inflammation, fibrosis, and early death in afflicted boys.

57 mbra, a clinically relevant region of stroke-afflicted brain.

58 erol has been shown to be misregulated in AD-afflicted brains, and the aberrant activity of proteins

59 nderlie the onset of edema and ICP in cancer-afflicted brains.

60 with a devastating impact not only upon the afflicted but also upon their families and the broader s

61 ose of sharply reducing the number of people afflicted by AD.

62 le and prothrombotic state among individuals afflicted by advanced-stage OSCC.

63 of preserving muscle function in individuals afflicted by chronic disease.

64 nic obstructive pulmonary disease (COPD) are afflicted by comorbidities.

65 rom each of sixty-eight 11-year-old children afflicted by different degrees of both gingivitis and ob

66 All cellular life forms are afflicted by diverse genetic parasites, including viruse

67 Boys afflicted by DMD typically exhibit symptoms within 3-5 y

68 ty principally supports host metapopulations afflicted by facultative pathogens.

69 loping interventions for clinical conditions afflicted by fatigue.

70 loping interventions for clinical conditions afflicted by fatigue.

71 -bearing (i.e., N, Cl, S) compounds has been afflicted by fractionation bias due to formation of bypr

72 ACHD patients continue to be afflicted by increased mortality in comparison with the

73 roaches provide temporal specificity but are afflicted by mosaicism and toxicity.

74 Studies of patients afflicted by neurodegenerative diseases suggest that mis

75 glial cells might provide benefit for those afflicted by neurodegenerative disorders.

76 They are afflicted by notorious causality issues (e.g. grandfathe

77 n of the population in countries/territories afflicted by outbreaks is still at risk of infection dur

78 the time period over which humans have been afflicted by such diseases is only known for very few ba

79 nd obesity share the core feature that those afflicted by the disorders express a desire to limit dru

80 tive breast cancer cells.IMPORTANCE Patients afflicted by triple-negative breast cancer have decrease

81 rtex (PFC) is particularly sensitive to, and afflicted by, exposure to stress.

82 g disorders were conceptualized as primarily afflicting Caucasian adolescent or young adult women wit

83 hboring cells and apoptosis to eliminate the afflicted cell.

84 These pathogens disproportionately afflict children in developing countries, where they cau

85 ation of future therapies to a population of afflicted children in serious need.

86 o extend the survival and quality of life of afflicted children.

87 t of recurrent respiratory papillomatosis in afflicted children.

88 wasaki disease is a vasculitis most commonly afflicting children <5 years of age.

89 , motor, and psychological deficits commonly afflicting cocaine abusers, yet the underlying mechanism

90 reverse causation and measurement error can afflict conventional mediation approaches and may lead t

91 Certain disease states that afflict critically ill patients may also amplify an inte

92 ions of the MG constitute the main pathology afflicting dairy cows.

93 biotics and prevent infections that commonly afflict developing infants.

94 oprioceptive sensory neurons are exclusively afflicted early in the disease process relative to senso

95 Plague continued to afflict Europe for more than five centuries after the Bl

96 Those afflicted experience frequent disfluencies during ongoin

97 -melanoma skin cancer is a disease primarily afflicting geriatric patients as evidenced by the fact t

98 the recently discovered SARS-CoV-2 virus has afflicted >6.9 million people worldwide and disrupted th

99 ic flatworms that cause debilitating disease afflicting >200 million people.

100 n is the most common cardiovascular disease, afflicting >30% of adults.

101 Chronic pain is pervasive and afflicts >100 million Americans.

102 c value for treating male infertility, which afflicts >100 million men world-wide.

103 ue virus (DenV), an arboviral infection that afflicts >50 million individuals each year.

104 an antibiotic-resistant strain of S. aureus afflicting hospitals and communities worldwide.

105 g that the cyanobiont might have rescued its afflicted host by feeding photosynthetic carbon into a c

106 prevent LTP suppression by extracts from AD-afflicted human brains in hippocampal slices from knocki

107 cough is a relatively new infectious disease afflicting human beings, compared with other infectious

108 ealthy foods to benefit a number of diseases afflicting human beings.

109 f diseases such as dengue fever and malaria, afflicting human morbidity and mortality worldwide.

110 ation and resultant aneuploidy that uniquely afflicts human female oocytes (e.g., giving Down syndrom

111 Most neurodegenerative diseases that afflict humans are associated with the intracytoplasmic

112 GB) is one of the deadliest brain cancers to afflict humans, and it has a very poor survival rate eve

113 s they share a risk for many conditions that afflict humans.

114 common mosquito transmitted viral infection afflicting humans, estimated to generate around 390 mill

115 in neurobehavioral deficits similar to those afflicting humans.

116 Some species are vectors of diseases that afflict hundreds of millions of people each year.

117 xually transmitted diseases, infections that afflict hundreds of millions of people globally.

118 Chronic infection by hepatitis B virus (HBV) afflicts hundreds of millions worldwide and is sustained

119 Hospital-onset sepsis preferentially afflicted ill patients but even after risk-adjustment, t

120 PFC pyramidal cell NMDA circuits, which are afflicted in aging and schizophrenia.

121 influenced by arousal state, and is gravely afflicted in disorders such as schizophrenia, where ther

122 All afflicted individuals had an onset in early infancy with

123 ions in the BRCA1 and BRCA2 genes predispose afflicted individuals to breast, ovarian, and other canc

124 electrocardiogram) syndrome that predisposes afflicted individuals to cardiac arrhythmia and sudden d

125 ase allele-free ES cells can be derived from afflicted individuals without genome manipulation.

126 he detection of disease-causing mutations in afflicted individuals.

127 paralysis and eventually premature death of afflicted individuals.

128 stemic fibrosing disorder that predominantly afflicts individuals with advanced renal dysfunction.

129 ion in these monocytes and local [Ca(2+)] in afflicted joints are increased, probably contributing to

130 he decrease in Agtrap mRNA expression in the afflicted kidney by unilateral ureteral obstruction is a

131 symptoms of anxiety and affective disorders afflicting large populations of people.

132 re, the key mechanism discrepancies of water-afflicted Li-O(2) batteries are presented, concluding wi

133 The foot-and-mouth disease virus (FMDV) afflicts livestock in more than 80 countries, limiting f

134 According to our results, thymic NETs afflict males and whites primarily.

135 up of fatal neurodegenerative disorders that afflict mammals.

136 hanisms behind pancreatitis, it continues to afflict many families for whom the hereditary factors re

137 In EAE-afflicted mice, minocycline treatment significantly redu

138 Gulf War illness (GWI) afflicts military personnel who served during the Persia

139 ection by Plasmodium falciparum continues to afflict millions of people worldwide, with transmission

140 ntrolling the HIV epidemics that continue to afflict millions of people worldwide.

141 n immunodeficiency virus, which collectively afflict millions of people worldwide.

142 mania is a single-celled eukaryotic parasite afflicting millions of humans worldwide, with current th

143 hat is the leading cause of senile dementia, afflicting millions of individuals worldwide.

144 e of the greatest health problems worldwide, afflicting millions of people annually.

145 rns by causing an acute intestinal infection afflicting millions of people each year.

146 Type 1 diabetes is an autoimmune disorder afflicting millions of people worldwide.

147 ase (IBD) is an expanding autoimmune disease afflicting millions that remains difficult to treat due

148 Ocean, India, and Southeast Asia, ultimately afflicting millions.

149 Osteoarthritis afflicts millions of individuals across the world result

150 Neuropathic pain afflicts millions of individuals and represents a major

151 engue is a mosquito-borne viral disease that afflicts millions of individuals worldwide every year.

152 sis, Schistosoma haematobium worm infection, afflicts millions of people with egg-triggered, fibrotic

153 Hepatitis B virus (HBV) infection afflicts millions worldwide, causing cirrhosis and liver

154 ntral to allergic airway inflammation, which afflicts millions worldwide.

155 Neglected tropical diseases afflict more than 1 billion of the world's poorest peopl

156 Herpes simplex virus 1 (HSV-1) infections afflict more than 80% of the population worldwide.

157 Glaucoma is a leading cause of blindness, afflicting more than 60 million people worldwide.

158 ees, but little is known about the parasites afflicting most other pollinators, or the extent of inte

159 se of unilateral ureteral obstruction in the afflicted mouse kidney suggest that Usf1 decreases but U

160 nced neuronal SOC causes synaptic loss in HD-afflicted MSNs.

161 quate nutrition and infectious disease still afflict much of sub-Saharan Africa, although disorders r

162 symptoms were fever (11/11), localized pain afflicting muscles and/or joints (8/11), vascular and th

163 ed by uropathogenic Escherichia coli (UPEC), afflict nearly 60% of women within their lifetimes.

164 or discovery of biomarkers for diseases that afflict newborn and preterm infants.

165 Dark Spot Syndrome (DSS) afflicts numerous coral species and is widespread throug

166 diseases which affected artists or diseases afflicting objects of their art.

167 and myelodysplastic syndrome (MDS) primarily afflict older individuals.

168 of ageing is a prevalent brain disease that afflicts older persons and has been linked with cerebrov

169 ction and IL-17-producing cells are found in afflicted organs in humans and lupus-prone mice.

170 ed marker reflects disease in brain or other afflicted organs.

171 r characterized genes/diseases that commonly afflict other methods.

172 fic aortic valve disease (CAVD) increasingly afflicts our aging population.

173 Vascular calcification increasingly afflicts our aging, dysmetabolic population.

174 entia is a devastating and incurable disease afflicting over 35 million people worldwide.

175 Malaria afflicts over 200 million people worldwide, and its most

176 Lymphatic filariasis (LF) afflicts over 60 million people worldwide and leads to s

177 ions create a substantial burden on both the afflicted patients and society as a whole.

178 ainage, but, despite drainage, virtually all afflicted patients develop fibrosis and progress to end-

179 evastating disease, in which the majority of afflicted patients eventually experience relapse and die

180 More severely afflicted patients need a CCTV.

181 n causes for the loss of SepSecS activity in afflicted patients, and that these factors contribute to

182 al to halt or reverse disease progression in afflicted patients, even after the onset of neurological

183 o develop therapeutics to improve outcome in afflicted patients.

184 ially increase our knowledge and benefit the afflicted patients.

185 ed to enable identification and treatment of afflicted patients.

186 dramatically reduces the quality of life in afflicted patients.

187 presentation, outcome and susceptibility of afflicted patients.

188 sis is a destructive invasive mold infection afflicting patients with diabetes and hematologic malign

189 mpairment is the most prominent feature that afflicts patients and their families.

190 e in nearly every major chronic disease that afflicts patients.

191 thritis, a chronic inflammatory disease that afflicts peripheral synovial, axial, and entheseal struc

192 ment of peripheral vascular disease (PVD) in afflicted persons.

193 ized cause of acute coronary syndromes (ACS) afflicting predominantly younger to middle-aged women.

194 are nonischemic cardiomyopathies that often afflict previously healthy young patients; both diseases

195 ealing in cigarette smokers is caused by the afflicted regenerative potential of smoker PDLSC.

196 sease mechanisms, selectively target disease-afflicted regions, and achieve long-term therapeutic pro

197 smodium parasite, and to cure those that are afflicted, rely upon functional characterization of gene

198 underlying pathology that can progressively afflict REM atonia and midbrain dopaminergic centers.

199 (EMF) is a neglected disease of poverty that afflicts rural populations in tropical low-income countr

200 exacerbates the dystrophic phenotype of DMD-afflicted skeletal muscle by dysregulating muscle stem c

201 proaches for the management of diseases that afflict smokers.

202 Water scarcity afflicts societies worldwide.

203 utes to the dystrophic phenotype observed in afflicted subjects.

204 ing coronavirus disease 2019 (Covid-19) have afflicted tens of millions of people in a worldwide pand

205 mutations; surprisingly these mutations can afflict the endothelium by either cell autonomous or par

206 long-standing retinal (macular) lesions that afflict the fovea and thus use their peripheral vision e

207 ong the most common motor neuron diseases to afflict the human population.

208 ct copper homeostasis and characteristically afflict the nervous system.

209 geneous group of mitochondrial diseases that afflict the pediatric population.

210 endothelial cells and cardiomyocytes, which afflicted the beta-Gal-injected diabetic control mice.

211 s such that deep vein thrombosis exclusively afflicted the immunosuppressed patients whereas arteriti

212 ction in cattle and other ruminants, greatly afflicting the dairy industry worldwide.

213 ative diseases have the temporal hallmark of afflicting the elderly population.

214 V) cause substantial morbidity and mortality afflicting the ends of the age spectrum during the autum

215 urable neurodegenerative disorders primarily afflicting the pediatric population.

216 Here, we show ligand aggregation afflicts the activity profile of 1 in biochemical assays

217 needed for a disease that disproportionally afflicts the elderly.

218 agement of leukemia and all other conditions afflicting them, patients with CML and comorbidities may

219 to detect and describe ocular complications afflicting these survivors and to observe their occurren

220 ology and the widely prevalent diseases that afflict this epithelium.

221 w insights into the development and diseases afflicting this structure.

222 global cause of death and disproportionately afflict those living in low-income and lower-middle-inco

223 Heat stroke afflicts thousands of humans each year, worldwide.

224 the confined three-dimensional matrix of an afflicted tissue.

225 However, many disorders afflict tissues inaccessible to light microscopy in live

226 of therapeutic agents directly into focally afflicted tissues is the ideal for the treatment of dise

227 IL-33 is elevated in afflicted tissues of patients with mast cell (MC)-depend

228 is a large public health problem that mainly afflicts tropical and subtropical regions.

229 Major depressive disorder afflicts up to 10% of adolescents.

230 urotoxicity is a debilitating condition that afflicts up to 90% of patients with colorectal cancer re

231 onal process by which human beings, although afflicted with a remarkable degree of self-ignorance, ar

232 d oxidative stress in the brains of patients afflicted with Alzheimer disease (AD).

233 Individuals afflicted with Alzheimer's disease (AD) can develop slee

234 with nearly 50% of adults over the age of 85 afflicted with Alzheimer's disease.

235 nently the soft shell clam Mya arenaria, are afflicted with an epidemic transmissible disease of the

236 The desired outcome would be for patients afflicted with AN to be diagnosed and treated at an earl

237 tate), and 1.4% for alpha-humulene (nitrate) afflicted with an uncertainty factor of 2.

238 pal Gyrus, and Left Fusiform Gyrus, of those afflicted with AN.

239 cium accrual, to the benefit of our patients afflicted with arteriosclerotic valvular and vascular di

240 mation in preclinical models and in patients afflicted with chronic inflammatory diseases.

241 st hydrolysis, especially elastin from lungs afflicted with chronic obstructive pulmonary disease or

242 Patients afflicted with clinically significant vitreous floaters

243 Sanger resequencing in PCD-affected families afflicted with combined IDA and ODA defects, we found th

244 However, the temporary ileostomy is afflicted with complications and requires a second surgi

245 ng for POC1B mutation could benefit families afflicted with CORD.

246 tion of the respiratory tract of individuals afflicted with cystic fibrosis and chronic obstructive p

247 t source of morbidity and mortality in those afflicted with cystic fibrosis.

248 shes a chronic lung infection in individuals afflicted with cystic fibrosis.

249 macrophages isolated from wounds of patients afflicted with diabetes and healthy controls as well as

250 macrophages isolated from wounds of patients afflicted with diabetes and of healthy controls and foun

251 The increasing number of people afflicted with diabetes throughout the world is a major

252 f the estimated 422 million people currently afflicted with diabetes worldwide, about 5% have type 1

253 verify, that individuals were quasirandomly afflicted with different intensities of war experience-t

254 ant muscle and bone loss occurring in people afflicted with disuse atrophy on Earth as well as in ast

255 of EMMPRIN on T cells in culture and in mice afflicted with EAE.

256 In many of the families afflicted with either disease, causative mutations have

257 of the chloroplast genome, a technology not afflicted with epigenetic variation and/or instability o

258 this new inhibitory scaffold to treat humans afflicted with filamentous fungal infections.

259 terventions for the treatment of individuals afflicted with Fragile X syndrome.

260 ntervention for the treatment of individuals afflicted with FXS.

261 a is a near-universal occurrence in patients afflicted with glioblastoma and it is almost exclusively

262 iological data reveal that of all the people afflicted with H1N1 virus, <5% are over 51 y of age.

263 tore other astrocytic transporter activities afflicted with HD.

264 llowed by homing to the liver and to a joint afflicted with hemarthrosis.

265 profiles between AD or PD patients to those afflicted with herpes viral infections as to discover no

266 We recently identified 2 siblings afflicted with idiopathic, autosomal recessive aplastic

267 management and quality of life for patients afflicted with ischemic and nonischemic heart muscle dis

268 ein levels, mimicking phenotypes in patients afflicted with LGMD2H.

269 therapy treatment, these patients are still afflicted with many complications including cognitive dy

270 anifestation of pediatric and adult patients afflicted with Marfan syndrome (MFS), a multisystem diso

271 Spina bifida (SB) patients afflicted with myelomeningocele typically possess a neur

272 oblastomas survived poorly relative to those afflicted with non-ZM-harboring sGBMs (P < 0.001).

273 lcohol, or was illiterate were significantly afflicted with ocular diseases (p < 0.05).

274 of FMF patients but not in cells of patients afflicted with other autoinflammatory diseases.

275 C646 administration in mice afflicted with p53-mutant tumors protected them from dox

276 eral publicly available datasets of patients afflicted with pancreatic, breast, colon and colorectal

277 For example, humans and cats are afflicted with pandemic AIDS lentiviruses that are susce

278 with arthritis on only one side, the one not afflicted with paralysis.

279 tment to subgingival debridement in patients afflicted with peri-implantitis.

280 y cause behavioral abnormalities in patients afflicted with psychosocial diseases.

281 er retinal dysfunctions in patients formerly afflicted with ROP.

282 the first potential gene therapy for females afflicted with RTT.

283 provide therapeutic benefit for the patients afflicted with SCA2 and possibly other SCAs.

284 ve duty US marine serving in Okinawa, Japan, afflicted with severe CNS angiostrongyliasis marked by r

285 However, each year, 1 million Americans are afflicted with severely reduced visual acuity caused by

286 Individuals afflicted with shingles risk developing the painful cond

287 l that a FOXP3 mutant found in some patients afflicted with the autoimmune disease IPEX has broadened

288 a striking increase in the number of people afflicted with the MetS.

289 o dramatically improve outcomes for patients afflicted with this aggressive and often incurable malig

290 applications of imiquimod to treat patients afflicted with this chronic fungal infection.

291 the groundwork for clinical trials in humans afflicted with this chronic, debilitating neurodegenerat

292 nsive to hormone therapies, leaving patients afflicted with this disease with limited treatment optio

293 o new therapeutic approaches for individuals afflicted with this disease.

294 ations elicit genomic instability and people afflicted with this syndrome developed hepatocellular ca

295 and limited therapeutic options for patients afflicted with this type of breast cancer.

296 ide a potent therapeutic option for patients afflicted with triple-negative breast cancer.

297 may facilitate outward expansion of arteries afflicted with TV.

298 Clinically, patients afflicted with ZM fusion harboring glioblastomas survive

299 itis of unknown aetiology that predominantly afflicts young children, causes coronary artery aneurysm

300 C) is a highly lethal malignancy that mainly afflicts young individuals of African descent and is res