ライフサイエンスコーパス: aggregate in

1 uent self-assembly of pentamer 1 into larger aggregates (in 80% methylcyclohexane/20% chloroform).

2 tive to geometric frustration if the columns aggregate in a hexagonal rod packing.

3 of 37 glutamine residues, htt(e1) starts to aggregate in a nucleation-dependent manner.

4 f the strong preference of the end groups to aggregate in a planar geometry.

5 trands of cells that detach and subsequently aggregate in a polar region.

6 red phases with O/Ti ratios around 1.37 that aggregate in a ~100 nm highly localized region electrica

7 At present, most of these data are aggregated in a cross-sectional fashion providing all me

8 uce seeding of alpha-syn monomers to produce aggregates in a dose-and time-dependent manner under sta

9 HEK293 cells increased the number of visible aggregates in a dose-dependent manner.

10 conjugates reduce the cytotoxicity of Abeta aggregates in a dose-dependent manner.

11 efers a beta-hairpin conformation which then aggregates in a downhill fashion at 0.1 mM.

12 samples; (2) the average size/proportion of aggregates in a population that do not specify the aggre

13 sequential spread and deposition of protein aggregates in a predictable pattern that correlates with

14 n the spatial distribution of red blood cell aggregates in a T-shaped bifurcation on the scale of a l

15 s with AuNPs protects the nanoparticles from aggregating in a high-salt solution.

16 d for in vivo imaging of neurofibrillary tau aggregates in AD with minimal off-target binding in the

17 omising PET tracers for visualization of tau aggregates in AD.

18 1) of the cooked products contained protein aggregates in addition to high molecular weight muscle p

19 accumulation of alpha-synuclein (alpha-syn) aggregates in affected oligodendrocytes.

20 ein TDP-43 forms intranuclear or cytoplasmic aggregates in age-related neurodegenerative diseases.

21 the size and number of ubiquitinated protein aggregates in aged flies, and increases longevity.

22 The tau protein aggregates in aging and Alzheimer disease and may lead t

23 slocalization of FUS and other proteins that aggregate in ALS/FTD and Parkinson's disease.

24 Moreover, the three main proteins aggregating in ALS/FTD, including in sporadic cases, are

25 wing that LSD1 localizes to pathological tau aggregates in Alzheimer's disease cases, and that it is

26 In fact, intracellular toxic protein aggregates in Alzheimer's disease form within the secret

27 roteins with prion-like domains (PrLDs) that aggregate in amyotrophic lateral sclerosis (ALS) and fro

28 ts against the toxicity of proteins known to aggregate in amyotrophic lateral sclerosis.

29 n and PLEKHM1 regulates clearance of protein aggregates in an autophagy- and LIR-dependent manner.

30 educes the progressive accumulation of PolyQ aggregates in an autophagy-dependent manner.

31 polycondensation of the same supramolecular aggregates in an electric furnace.

32 agocytosis in transfer of pathogenic protein aggregates in an intact brain.

33 and S262P, dramatically preventing them from aggregating in, and inhibiting motility of, podocytes, f

34 tein complexes encoded on excess chromosomes aggregate in aneuploid cells, which is suppressed when e

35 d these cells into PAX8(+)LHX1(+) pretubular aggregates in another 2 days.

36 Amphiphilic lipids aggregate in aqueous solution into a variety of structur

37 the mixing time was increased, the number of aggregates in as-spun TES-ADT thin films were increased

38 antibiotics--the sequestration of IOPs into aggregates in association with the chaperone ClpB, follo

39 ogressive supranuclear palsy (PSP), tau also aggregates in astrocytes and oligodendrocytes.

40 veloped fewer beta-amyloid precursor protein aggregates in axons of the corpus callosum after traumat

41 In the absence of EV71, AuNS-SCARB2 aggregated in biological media and produced four enhance

42 e analytical tool for characterizing protein aggregates in biopharmaceutical formulations.

43 itive, amplified measurement of pathological aggregates in biospecimens.

44 lein, and the prion protein (PrP) induced by aggregates in biospecimens.

45 n drive formation and disassembly of protein aggregates in both conformational states.

46 and subcellular localization of p53 amyloid aggregates in both EC and endometrial nontumor cell line

47 and develops a severe motor deficit and tau aggregates in brain and spinal cord.

48 deficits associated with accumulation of tau aggregates in brain, brainstem, and spinal cord.

49 rrier and co-localize with intracellular RAN aggregates in C9-ALS/FTD BAC mice.

50 ing a rationale for the presence of ferritin aggregates in cell types expressing different levels of

51 Bacteria cooperated by aggregating in cell clusters of ~10 to 20 um, in which c

52 smotic stress in inducing human alpha-syn to aggregate in cells in vitro, through rapid treatment of

53 commonly used approach for studying protein aggregates in cells is number and brightness (N&B), a fl

54 gs indicate that the rate at which alpha-syn aggregates in cells may be a significant factor in how i

55 d AggreCount to identify and measure protein aggregates in cells.

56 s also support a role for prion-like protein aggregates in cellular defense and adaptation.

57 assay to detect alpha-synuclein (alpha-syn) aggregates in cerebrospinal fluid (CSF) of 118 patients

58 rocytes themselves were infected; astrocytes aggregated in clusters.

59 ame slightly deformed, and finally it became aggregated in conventional DOPC, POPC, and DMPC membrane

60 ase that solubilizes and reactivates protein aggregates in cooperation with the DnaK/Hsp70 chaperone

61 lerance in yeast by recovering proteins from aggregates in cooperation with the Hsp70 chaperone.

62 ferent species of disulfide-dependent TDP-43 aggregates in cortex and spinal cord tissue.

63 ence of perivascular hyperphosphorylated tau aggregates in cortical tissue (McKee et al., 2016, Acta

64 gn circRNA, and RIG-I and foreign circRNA co-aggregate in cytoplasmic foci.

65 ndant presence of ubiquitin and p62-positive aggregates in degenerating Purkinje cells coupled with t

66 ces in cellular and regional distribution of aggregates in different synucleinopathies.

67 yloid fibrils and accumulate as pathological aggregates in different tissues.

68 g chemical matter and mitigate the impact of aggregates in discovery programmes.

69 and B) can arise; however, the role of these aggregates in disease pathogenesis has not been fully ch

70 The precise role of the aggregates in disease progression has been difficult to

71 sues and may play a role in the formation of aggregates in disease.

72 the transmission and propagation of protein aggregates in disease.

73 standing of cell-to-cell transmission of tau aggregates in dividing cells and possibly neurons.

74 or types of AD-relevant tau pathologies: tau aggregates in dystrophic neurites surrounding Abeta plaq

75 single-cell resolution and then signals were aggregated in each cell population separately.

76 cal heterogeneity, despite the fact that tau aggregates in each disease.

77 point to the formation of different types of aggregates in each ionic liquid.

78 mbly demonstrate the presence of oligo-chain aggregates in early stages of copolyelectrolyte assembly

79 occupy broad thermal distributions that are aggregated in either temperate or tropical realms.

80 ad formation of EBS-like cytoplasmic keratin aggregates in epithelial and non-epithelial fly tissues.

81 Causal variants that aggregate in families usually have larger effect sizes t

82 Each of these disorders aggregates in families and is moderately heritable.

83 ardiomyopathy in younger persons (<50 years) aggregates in families at the population level is unclea

84 Cognitive ability strongly aggregates in families, and prior twin and adoption stud

85 al changes in the N-terminal region of Abeta aggregates in favor of less compact conformations.

86 re of cells to EGF, with a decrease in ACTN4 aggregates in fibroblasts.

87 The formation of water-stable aggregates in finely textured and polymineral magnetite

88 itive cores increased with the sum of scores aggregated in five classes as follows: For summed PI-RAD

89 ns selectively stain nuclear and cytoplasmic aggregates in FXTAS patients and colocalize with ubiquit

90 cessibility of zeaxanthin from these tubular aggregates in goji berries as compared to protein-comple

91 Accumulation of mutated AAT protein aggregates in hepatocytes leads to endoplasmic reticulum

92 hese bio-physical changes provoke Sesarma to aggregate in high-density grazing and burrowing fronts a

93 When the installation was illuminated, birds aggregated in high densities, decreased flight speeds, f

94 eding mechanisms of alpha-synuclein (alphaS) aggregates in human cells, we visualized alphaS aggregat

95 at the (3)H-T808 binding site on native tau aggregates in human late-stage AD brain tissue.

96 Aggregates in human myocardium were enriched for cofilin

97 ble therapeutic pathways capable of reducing aggregates in human neuronal model systems.

98 ne, the device detects the presence of Abeta aggregates in human serum samples with excellent sensiti

99 istor (OECT) for in vitro detection of Abeta aggregates in human serum.

100 ions, forms exceptionally strong biofilmlike aggregates in human synovial fluid (SF), to an extent si

101 to be deposited as amyloid or other types of aggregates in human tissues and the disorders with which

102 characterization of prefibrillar myocardial aggregates in humans and the first report to link cofili

103 participation by both soluble and fibrillar aggregates in IAPP-induced islet inflammation.

104 e therefore investigated how ASD and ADHD co-aggregate in individuals and in families to test for the

105 Tau-related alterations aggregated in large genomic segments reflecting spatial

106 's disease (PD), and alpha-synuclein protein aggregates in Lewy bodies and Lewy neurites in sporadic

107 ptic protein that forms abnormal cytoplasmic aggregates in Lewy body disorders.

108 Perfluorinated long chain alkyl amides aggregate in liquid ammonia with increasing concentratio

109 sh unfolded protein oligomers from insoluble aggregates in live cells.

110 Routine detection of hemosiderin iron aggregates in macrophages in other settings histological

111 The widespread occurrence of these aggregates in many different ecosystems suggests that ge

112 & DAOY, respectively), plated as spheroidal aggregates in Matrigel-filled electrotaxis channels, and

113 ctive invasion in vitro when implanted as 3D aggregates in Matrigel.

114 g a weak role of physical protection by soil aggregates in mediating microbial responses to altered s

115 iaryl chelate unit have been found to form J-aggregates in methanol-water solvent mixture and brightl

116 ction of pathologic tau led to increased tau aggregates in mice in which p.Asp395Gly VCP mice was kno

117 structural and functional features have been aggregated in MISCAST from multiple databases, and displ

118 the photophysical properties of astaxanthin aggregates in mixed-solvent systems and proteins shows t

119 ligation assay labels very early perikaryal aggregates in morphologically intact neurons that may pr

120 Given the persistent presence of fibronectin aggregates in MS lesions, ganglioside GD1a might act as

121 We found that mucoadhesive particles (MAP) aggregated in mucus in the center of the GI lumen, far a

122 Line 66 mice express intracellular tau aggregates in multiple brain regions and exhibit sensori

123 ssociated protein tau accumulates into toxic aggregates in multiple neurodegenerative diseases.

124 roteins accumulate as insoluble intranuclear aggregates in muscles of OPMD patients.

125 vation accelerates the spread of tau protein aggregates in neural networks.

126 ne reason is that the amount of pathological aggregates in neural tissue is exceedingly low, precludi

127 ations (PTMs) are common among proteins that aggregate in neurodegenerative disease, yet how PTMs imp

128 Misfolded proteins accumulate and aggregate in neurodegenerative disease.

129 articular, numerous proteins that form toxic aggregates in neurodegenerative diseases, such as amyotr

130 d to enhance autophagic clearance of protein aggregates in neurodegenerative disorders.

131 k of LD is the presence of abnormal glycogen aggregates in neurons and other tissues.

132 TDP-43 is an RNA-binding protein which forms aggregates in neurons of ALS and FTD patients as well as

133 s of certain metal ions are found in protein aggregates in neurons of people suffering from PD, and e

134 induced an accumulation of cytoplasmic ATXN3 aggregates in neurons of SCA3 mice.

135 ression (ASOX) drives the formation of toxic aggregates in neurons vulnerable in Parkinson's disease

136 causes the formation of larger pathological aggregates in neurons, accompanied by impairments in its

137 In Alzheimer's disease (AD), tau aggregates in neurons, while in corticobasal degeneratio

138 Htt protein in human patient fibroblasts and aggregates in neurons.

139 DISC1 rat displayed mainly perinuclear DISC1 aggregates in neurons.

140 trains that propagate neuronal and glial tau aggregates in nontransgenic (nonTg) mouse brain.

141 RIOK3 was localised to distinct cytoplasmic aggregates in normoxic cells and underwent redistributio

142 rophy is the accumulation of alpha-synuclein aggregates in oligodendrocytes, forming glial cytoplasmi

143 glutamine-expanded Huntingtin construct that aggregates in other model organisms tested.

144 track the formation of heat-induced protein aggregates in otherwise unperturbed dividing cells.

145 xpressed alpha-synuclein, a protein known to aggregate in Parkinson's disease, dementia with Lewy bod

146 are derived from alpha-synuclein, a protein aggregated in Parkinson's disease, act as antigenic epit

147 els of alpha-synuclein, a protein present as aggregates in Parkinson disease and related synucleinopa

148 alphaS) self-assembles into toxic beta-sheet aggregates in Parkinson's disease, while it is proposed

149 f alpha-synuclein, a protein forming amyloid aggregates in Parkinson's disease.

150 ere termed food set selection) was spatially aggregated in patches and how food aggregation varied ac

151 e 1 (SOD1), which is known to form misfolded aggregates in patients with amyotrophic lateral sclerosi

152 , hnRNPA1 and hnRNPA2/B1 formed sarcoplasmic aggregates in patients with LGMD1D.

153 lso frequently found in neuronal cytoplasmic aggregates in patients with neurodegenerative diseases n

154 ocardial tissue showed no abnormal filamin C aggregates in patients with truncating FLNC mutations.

155 The gyroidal ionic aggregates in PES23Li and PES23Na further evolve into he

156 g measurements reveal that the layered ionic aggregates in PES23Li, PES23Na, and PES23Cs transform, u

157 The presence of such large, organized lipid aggregates in plant cell walls represents a new mechanis

158 s have an accumulation of cytoplasmic TDP-43 aggregates in postmortem brain and spinal cord (SC), it

159 s suggest that the dominance of subfibrillar aggregates in prion disease is due to the replication of

160 of strain variation and the role of PrP(Sc) aggregates in prion-induced neurodegeneration.

161 but tissue studies assessing binding to tau aggregates in progressive supranuclear palsy (PSP) have

162 Light is known to induce covalently linked aggregates in proteins.

163 Zn-carboxylate complex with Zn-stearate nano-aggregates in proximity are distributed randomly in the

164 A large part of the variant level data is aggregated in public databases such as ClinVar.

165 The presence of nonphysiological aggregates in purified properdin preparations and experi

166 While the formation of non-physiological aggregates in purified properdin preparations and the pr

167 structures in H4 cells, and alpha-synuclein aggregates in rat hippocampal neurons.

168 When not feeding on human blood bed bugs aggregate in refuges close to human hosts.

169 Here, we show that Foxp3+ T cells formed aggregates in rejection-free human lung grafts and accum

170 a glycolytic deficiency syndrome, also forms aggregates in response to cadmium treatment, suggesting

171 hydrophilic nanoscale reagents to microscale aggregates in response to temperature stimuli.

172 (R2TP) complex and the formation of protein aggregates in response to thermal stress.

173 eviously been used to detect alpha-synuclein aggregates in samples of cerebrospinal fluid with high s

174 ted the transcellular propagation of protein aggregates in several major neurodegenerative diseases,

175 re, polyglutamine (polyQ) repeats form toxic aggregates in several neurodegenerative diseases.

176 we demonstrate that particles spontaneously aggregate in SI luminal fluid ex vivo.

177 t genomes where protein coding genes tend to aggregate in significantly biased (p < 0.001) manner com

178 ntrolling the self-assembled nanoscale ionic aggregates in single-ion conducting polymers is a crucia

179 also alter the structure of alpha-synuclein aggregates in site-specific ways.

180 eveal the fibrillary structure of huntingtin aggregates in situ and show that huntingtin fibrils inte

181 iculties, proximal limb weakness and nuclear aggregates in skeletal muscles.

182 termination of the structure and quantity of aggregates in small tissue samples, circumventing the ab

183 In solutions below pH 3.0, the Au NPs aggregate in solution and attach to the electrode in the

184 The high propensity of RD3 to aggregate in solution has prevented structural analysis.

185 tion also results in an enhanced tendency to aggregate in solution, which is ascribed to a more co-pl

186 This sequence spontaneously aggregates in solution to form fibrous structures and hy

187 he simulations reveal formation of molecular aggregates in solution, which on coming in contact with

188 y epidemic alert systems are typically fully aggregated in space at the national level.

189 ocused primarily on single interaction types aggregating in space or time.

190 he presence of B and T cell lymphocytes that aggregate in specific body sites to form primary and sec

191 Telomeres and centromeres were observed to aggregate in sperm nuclei, forming an average of 20 and

192 a stable component of nuage that is able to aggregate in the absence of other nuage proteins.

193 deling of membranes suggests these compounds aggregate in the center of the lipid bilayer, potentiall

194 epting molecule can generate a new molecular aggregate in the ground state, called an electron donor-

195 The lipopeptides aggregate in the lipopolysaccharide headgroup region of

196 o not hone to the site of defect but instead aggregate in the location of injection, which suggests t

197 polyethilenimine (bPEI)-coated AgNPs tend to aggregate in the presence of algae and interact with tes

198 crocycle 1 forms a self-assembled tetrameric aggregate in the solid state and in methanol.

199 and isotope analyses of a large (~10 mum) OM aggregate in the Zag clast.

200 Acetylcholine receptors are aggregated in the central regions of intrafusal muscle f

201 ), as a bona fide ERAD substrate that became aggregated in the endoplasmic reticulum following ERAD d

202 lysis revealed that the majority of variants aggregated in the MAPK, ErbB and RAS signaling pathways.

203 Metabolic changes were aggregated in the quantitative metabolic effect level in

204 I) actually share pathogenesis and should be aggregated in the same diagnostic group remains an open

205 7.5 hours, the time frame within which IAPP aggregates in the absence of polyphenols.

206 erative tauopathies exhibit pathological tau aggregates in the brain along with diverse clinical feat

207 e accumulation of plaques of alpha-synuclein aggregates in the brain cells.

208 dence also suggests that accumulation of tau aggregates in the brain correlates with decreased nonrap

209 The deposition of tau protein aggregates in the brain is a pathological hallmark of de

210 ques containing amyloid beta (Abeta) peptide aggregates in the brain of Alzheimer's disease (AD) pati

211 ative difference between Abeta40 and Abeta42 aggregates in the brain tissue of patients with Alzheime

212 sease (AD), the amyloid beta (Abeta) peptide aggregates in the brain to form progressively larger oli

213 gional deposition of misfolded prion protein aggregates in the brain, and size of their protease-resi

214 l cross-seeding between DISC1 and mutant HTT aggregates in the brains of HD patients as well as in a

215 ing electron microscopy (SEM) but only small aggregates in the case of Zn(2+).

216 proteins (INP) are typically large and form aggregates in the cell membrane, while insect hyperactiv

217 B cell aggregates in the central nervous system (CNS) have been

218 t the characteristics of the alpha-synuclein aggregates in the cerebrospinal fluid could be used to r

219 on of proteinase K-resistant alpha-synuclein aggregates in the CNS and was accompanied by the normali

220 in, an intrinsically disordered protein that aggregates in the context of Parkinson's disease.

221 's disease (PD), the prevalence of alpha-syn aggregates in the cortices of sporadic disease cases emp

222 al activities of the largely synthetic Abeta aggregates in the culture are very similar to those obse

223 tationary phase by formation of amyloid-like aggregates in the culture.

224 ce and homo-polymerization of DNM1L, forming aggregates in the cytoplasm and on highly tubulated mito

225 orm detergent-resistant, hyperphosphorylated aggregates in the cytoplasm of affected neurons and glia

226 dox systems resulted in an increase of hSOD1 aggregates in the cytoplasm of cells transfected with mu

227 n a complex and poorly understood manner and aggregates in the cytoplasm of degenerating neurons in P

228 0 is toxic when assembled into C-I and forms aggregates in the cytosol.

229 fluorescent tag to monitor the spreading of aggregates in the Drosophila brain in a model of Hunting

230 the porous medium and detection of nano-size aggregates in the effluent show that the solubilization

231 whereas glycosylation-deficient CLRN1(N48K) aggregates in the endoplasmic reticulum, with only a fra

232 ss, a progressive locomotor defect, abnormal aggregates in the ER and increased levels of the ER stre

233 The fluorescent secretory protein forms aggregates in the ER lumen and can be rapidly disaggrega

234 Here, we show that Can GPC aggregates in the ER of infected cells, forming incorrec

235 al of injected mice was determined, and SOD1 aggregates in the facial nuclei were quantified during d

236 athione regulation leading to higher product aggregates in the fed-batch process.

237 The present study demonstrates that large aggregates in the form of multivesicular inclusions form

238 ated with the accumulation of pathologic tau aggregates in the form of neurofibrillary tangles.

239 l as huntingtin-positive, ubiquitin-positive aggregates in the frontal cortex.

240 Given the prevalence of Medin aggregates in the general population and its role in vas

241 Viruses may form crystal like structures and aggregates in the host cell during replication or may fo

242 n about the characteristics of soluble Abeta aggregates in the human Alzheimer's disease brain.

243 east 12 of the analyzed grains were parts of aggregates in the interstellar medium: The large differe

244 development of new PET tracers to image tau aggregates in the living human brain.

245 n the mesenchyme, urothelium, and follicular aggregates in the majority of patients, indicating that

246 The inserted peptides formed aggregates in the membrane core leading to further struc

247 nduces the formation of large nisin-Lipid II aggregates in the membrane of bacteria as well as in Lip

248 y indicate that statins form nanometer-sized aggregates in the membrane.

249 Sequestration of platelet-neutrophil aggregates in the microvasculature contributes to tissue

250 r 1 (PABPN1) gene leads to PABPN1-containing aggregates in the muscles of OPMD patients.

251 The presence of hierarchical dust aggregates in the near-surface of the nucleus of comet 6

252 sis and transcellular propagation of protein aggregates in the nervous system.

253 ral sclerosis (ALS) can have abnormal TDP-43 aggregates in the nucleus and cytosol of their surviving

254 olocalize near large central heterochromatin aggregates in the OSN nucleus, Taar genes are located pr

255 Most of the BM-MSCs formed aggregates in the peritoneal cavity.

256 t localize to the intestine but instead form aggregates in the peritoneum where they produce immunore

257 as predominantly covered by the CN and CN-WP aggregates in the presence of equal or greater amounts o

258 LTN1 results in the accumulation of protein aggregates in the presence of oxidizing and alkylating a

259 otor neuron cells, often forming cytoplasmic aggregates in the process.

260 sensitive to an increase in soluble protein aggregates in the range of <1.0%.

261 161H), we identified well-organized lymphoid aggregates in the retina and examined them for TLT chara

262 Our findings suggest that the lymphoid aggregates in the retina of R161H mice represent organiz

263 group, the dyes restrained the formation of aggregates in the solid state.

264 iazine restrained the formation of molecular aggregates in the solid state.

265 A subunit, which was observed as perinuclear aggregates in the somata of the frontal cortex of SIV-in

266 DIM adopts a conical shape in membranes and aggregates in the stalks formed between 2 opposing lipid

267 e release from HD astrocytes as well as mHtt aggregates in the striatum of HD140Q KI mice.

268 o D(h) = 130 +/- 10 nm and remained as large aggregates in the upper intestinal compartments (duodenu

269 these pathways localize to, or form distinct aggregates in the vicinity of, germ granules.

270 ion, suggesting an irregular distribution of aggregates in the z-direction.

271 of nonfilamentous high-molecular-weight tau aggregates, in the absence of tau filaments.

272 In T2D patients IAPP is found aggregating in the extracellular space of the islets of

273 bugs to 'hitch-hike' around the world after aggregating in the laundry bags of travellers.

274 fically mislocalized to pathological protein aggregates in these cases.

275 ial analysis showed that rapid renal decline aggregates in these families and is associated with its

276 vivo selective and reliable detection of tau aggregates in these non-Alzheimer tauopathies.

277 o our devices, we follow the growth of these aggregates in time and show that their length does not d

278 PABPN1 is linked to the formation of nuclear aggregates in tissues from individuals with OPMD.

279 d to NEFH caused prominent and toxic protein aggregates in transfected cells and disrupted motor neur

280 other membrane proteins, as well, and desmin aggregates in transfected cells expressing the mutant de

281 to bind to or splice RNA, it forms abundant aggregates in transfected cells.

282 increasing levels of intravascular platelet aggregates in tumor specimens (P < .001).

283 roscopic images indicated presence of larger aggregates in unstabilised powder (RC) compared to well-

284 rized by the appearance of nonnative protein aggregates in various tissues.

285 lly discuss the possible role played by such aggregates in vaso-occlusive events.

286 icus (Sso AcP) is a globular protein able to aggregate in vitro from a native-like conformational ens

287 from human tissue in comparison with fibrils aggregated in vitro.

288 t that D-520 inhibits the formation of Abeta aggregates in vitro and promotes the disaggregation of b

289 on and disintegration of alpha-syn and Abeta aggregates in vitro using purified proteins and in a cel

290 oid structures, and the staining of amyloids aggregates in vitro, ex vivo, and in vivo.

291 induce structural changes in alpha-synuclein aggregates in vitro.

292 ents coinciding with mutant huntingtin exon1 aggregate in vivo and induce HD-like pathology in mouse

293 e investigate the mechanism by which Sso AcP aggregates in vivo to form bacterial inclusion bodies af

294 in tracking the dynamics and fate of protein aggregates in vivo.

295 ash and occurrence of concentrically layered aggregates in volcanic deposits.

296 The aggregates in water were investigated by dynamic light s

297 ht into the structure of well-defined chiral aggregates in which a lithium amide reagent directs asym

298 to a synergic role of Ag and Pt in ultranano-aggregates, in which Pt anchors the clusters to the supp

299 e mass-spectrometry of mycobacterial protein aggregates in wild-type, hspX-deleted and hspX-overexpre

300 y we have defined the range of proteins that aggregate in yeast cells during normal growth and after