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1 red lactone macrolides based on spiramycin's aglycone.
2 ete decomposition/transformation of terpenyl aglycone.
3 O-sophoroside, compared to that of quercetin aglycone.
4 bled the convergent total synthesis of G-CSF aglycone.
5 ety attached via a carbon-carbon bond to the aglycone.
6 hosphate, and Teg12 bound to the teicoplanin aglycone.
7 s further elaborated to a protected candidin aglycone.
8 ntical to the naturally derived landomycin A aglycone.
9 cis relationship between the epoxide and the aglycone.
10 phosphodiester linkage to a phosphoglyceride aglycone.
11 -1), for an alternate substrate, teicoplanin aglycone.
12 te and monolignol precursor to the etoposide aglycone.
13 nd structural reassignment of justicioside E aglycone.
14 norisoprenoid glucoside in comparison to its aglycone.
15 the fact that they release the same aromatic aglycone.
16 e potentials were higher than those of their aglycones.
17 glucosides, 72.9% malonylglucosides and 1.2% aglycones.
18 sidase and convert glycosidic isoflavones in aglycones.
19 through hydrolysis to give the corresponding aglycones.
20 , digoxin, digitoxin, and gitoxin with their aglycones.
21 nferring biological activities to its parent aglycones.
22 gut requires deconjugation of glucosides to aglycones.
23 d aglycone equivalents, primarily (95.8%) as aglycones.
24 benzimidazole and 2-quino-2-benzimidazole as aglycones.
25 he enzymes that biosynthesize the glycolipid aglycones.
26 within tissues and cells than do polyphenol aglycones.
27 leomycin A(2) (4), as well as the respective aglycones.
28 es), although occasionally they are found as aglycones.
29 clover contains mostly easily absorbed free aglycones.
30 cosides were, in most cases, equipotent with aglycones.
31 nst bone loss may be enhanced for isoflavone aglycones.
32 avone composition in mediating conversion to aglycones.
33 with isorhamnetin and quercetin as the major aglycones.
35 caffeic acid, and decarboxymethyl oleuropein aglycone (3,4-DHPEA-EDA) in the salivary and gastric pha
36 DHPEA-EDA (6) and oleuropein (1), oleuropein aglycone (4) and hydroxytyrosol ORACFL values was undert
37 The enantiomer of the bicyclic lomaiviticin aglycone A core was prepared via a two-directional, dive
38 '-desmethylepipodophyllotoxin (the etoposide aglycone), a naturally occurring lignan that is the imme
39 inds TDP in the interdomain cleft, while the aglycone acceptor binds in a deep crevice in the N-termi
41 rgely unknown whether structural features of aglycone affect the extent of sulfation, sulfation patte
42 le extract was readily converted to apigenin aglycone after combination with almond, flax seed, or ch
43 the identities of four glucosides and seven aglycones, among them vanillin (5.7/100 g), 4-hydroxyben
44 strate that gossypin (and not gossypetin, an aglycone analog) inhibited NF-kappaB activation induced
45 the closely related (-)-deacetoxy-oleuropein aglycone and a series of related analogues for structure
47 The major phenolic acids, some flavonoid aglycone and glycosides were identified in leaves by hig
52 des to acetylglycosides, beta-glycosides and aglycones and a significant reduction in the activity of
54 spectrometry (APCI-MS/MS) of citrus limonoid aglycones and electrospray ionization tandem mass spectr
59 red clover extract (RCE) rich in isoflavone aglycones and probiotics to concomitantly promote uptake
60 en Vibrio cholerae also encodes rhabduscin's aglycone, and bacterial cell-coated immunosuppressants c
61 ied oleuropein aglycone, hydroxyl oleuropein aglycone, and oleuropein as key compounds responsible fo
62 (194) forming stacking interactions with the aglycone, and the hydrogen bond between the His(195) nit
65 ce a better product, due to lower amounts of aglycones, and higher protein nutritional quality than h
66 tyl glycosides were about twice as active as aglycones, and the peracetyl glycosides were, in most ca
68 vonoid rutin to understand its hydrolysis to aglycones, antioxidant capacity and optical rotation.
73 eroids 19-hydroxysarmentogenin and trewianin aglycone as well as to the assembly of the panogenin cor
74 eneration of the highly cross-linked peptide aglycone at the core of this compound class that is requ
75 tion by various cardiac glycosides and their aglycones at different pH values using shark Na,K-ATPase
76 soflavone conjugates may serve as sources of aglycones at specific target tissues and may have bioact
79 olic acids, their derivatives, and flavonoid aglycones based on their molecular masses and fragmentat
81 rate complexes of Dhr1 show that the mode of aglycone binding differs from that previously observed i
82 bserved in the surface loops surrounding the aglycone binding site, and these are likely to strongly
83 259), Phe(261), and Ser(462), located in the aglycone-binding site of S. bicolor Dhr1, are crucial fo
84 p378, Phe466, and Ala467) are located in the aglycone-binding site of ZmGlu1 and form the basis of ag
87 MPK, an effect also seen with phloretin (the aglycone breakdown product of phlorizin), but not to any
88 ng (ABMP) employing a physiologic library of aglycones built from glycosides isolated from grape.
90 he NOCAP (nocardiosis-associated polyketide) aglycone by first fully reconstituting the NOCAP synthas
91 on of chloroeremomycin from the heptapeptide aglycone by the sequential actions of the three enzymes.
92 ing benzoic acids, cinnamic acids, flavonoid aglycones, C- and O-glycosides, coumarins, and lignans)
95 om cocrystals of enzyme-substrate and enzyme-aglycone complexes have shown that five amino acid resid
96 a relation between the molecular weights of aglycone compounds and their anticholinesterase activiti
97 sted bioactivities except from the case that aglycone compounds exhibited a strong positive relations
98 structure and the antioxidant efficiency as aglycone compounds were significantly more efficient (p
101 rees C for 25min, the daidzein and genistein aglycone contents were maintained, the glycitein and bet
103 25 mug/d) given either RCE (60 mg isoflavone aglycones/d and probiotics) or a masked placebo [control
104 ldehydic forms of oleuropein and ligstroside aglycones (DAFOA and DAFLA), indicating a more active pa
106 the simultaneous determination of isoflavone aglycones (daidzein, glycitein and genistein), their cor
107 ds, pigment content and deacetoxy oleuropein aglycone (DAOA) content and didn't affect the sensory ch
109 n solution, makes use of the H-bond-mediated aglycone delivery method for the highly diastereoselecti
110 uring negative ion APCI analysis of limonoid aglycones, depending on the mobile-phase modifier used.
112 acid hydrolysis the area of released terpene aglycone did not exceed 1.3% of total peak area indicati
113 s of daily supplementation with 80 or 120 mg aglycone equivalent soy hypocotyl isoflavones plus calci
115 nistein compounds were measured expressed as aglycone equivalents per 100g of fresh fruit flesh.
116 8 g) + isoflavone tablets (105 mg isoflavone aglycone equivalents), soy protein + placebo tablets, co
119 yme contained 36.7% of ingested isoflavonoid aglycone equivalents, primarily (95.8%) as aglycones.
120 e blood and tissues are, in general, neither aglycones (except for green tea catechins) nor the same
121 uding increased allelopathic activity of the aglycone, facilitating exudation by roots and allowing s
126 dent on whether isoflavone treatments are in aglycone form; we conclude that beneficial effects again
127 tection was shown to be able to observe both aglycone formation and further reactions in isolated fra
128 y encoding three early enzymes of triterpene aglycone formation: squalene synthase (SS), squalene epo
134 uman oral microbiota to produce wine odorant aglycones from odourless grape glycosidic aroma precurso
139 s, and subsequent GC-MS determination of the aglycones, highlighted that the majority of norisoprenoi
140 ucosyldisaccharide chain on residue 4 of the aglycone; however, the characterization of GtfA and glyc
142 the Koroneiki extract identified oleuropein aglycone, hydroxyl oleuropein aglycone, and oleuropein a
146 r results enable production of the etoposide aglycone in tobacco and circumvent the need for cultivat
148 or nutritive and antinutritive phytochemical aglycones in edible African nightshade leaves, an underu
150 conversion of beta-glucoside isoflavones to aglycones in soymilk processing and to evaluate their th
151 en isolating studies that provide isoflavone aglycones in their treatment arm, the average effect was
152 of o-diphenols (hydroxytyrosol or oleuropein aglycone) in olive oil led to a lower oxidation rate und
154 erting diverse, fully synthetic polyphenolic aglycones into the corresponding glycosides in a whole-c
155 onversion of beta-glucosides into isoflavone aglycones involved soaking the soybeans at 5 degrees C f
156 rosporine by streptomycetes, assembly of the aglycones involves a complex set of oxidative condensati
157 e tetrahydro-beta-carboline of strictosidine aglycone is converted into akuammicine, a Strychnos alka
158 involved in elaboration of the rebeccamycin aglycone is encoded by rebO, located at the left-hand re
160 kefir-fermented soymilk is a good source of aglycone isoflavones and phenolics, since the content of
163 responding increase in the concentrations of aglycone isoflavones, with the magnitude of these change
164 ignificantly decreased the concentrations of aglycone isomers of oleuropein and ligstroside but, conv
172 substrates were identified by physiological aglycone libraries prepared from isolated plant glycosid
175 agmentation patterns of four citrus limonoid aglycones (limonin, nomilin, obacunone, and deacetylnomi
177 igate the first two reactions in teicoplanin aglycone maturation catalyzed by the enzymes OxyBtei and
178 tion of the primers and the structure of the aglycone moieties can affect the composition of the newl
183 lucosides, with specificity depending on the aglycone moiety, the type of sugar and the linkage betwe
185 activated dissociation (CAD) of the limonoid aglycone molecular ions in negative ion APCI analysis, f
186 and applied a suite of difluoromethylphenyl aglycone, N-halogenated glycosylamine, and 2-deoxy-2-flu
188 say method considers 13 flavanones including aglycones, neohesperidosides, rutinosides and 3-hydroxy-
190 and extended to deacylated anthocyanins and aglycones, obtained, respectively, by alkaline and acid
191 macrocyclic skeleton of rimocidinolide, the aglycone of (+)-rimocidin (1), has been achieved in conv
192 proposed structure (2) of landomycinone, the aglycone of landomycin A, has been synthesized and shown
195 or the biosynthesis of 6-dEB (1), the parent aglycone of the broad spectrum macrolide antibiotic eryt
196 ne was converted to (+/-)-idarubicinone, the aglycone of the FDA approved anthracycline idarubicin, t
198 ent, enantioselective total synthesis of the aglycone of the tetrocarcins, (+)-tetronolide, is descri
199 extraction the benzoic acid derivatives and aglycones of flavonoids showed lower recovery (70-80%).
200 zation and for quantification of eight major aglycones of polyphenols, alkaloids and sapogenins in 20
202 ed to the apoplast, we hypothesized that the aglycones of these compounds are made within the cell.
207 ost all such studies, cells are treated with aglycones or polyphenol-rich extracts (derived from plan
208 lightly differently oriented relative to the aglycone part if compared to that of spiramycin (1).
209 ng both coniferyl alcohol and main etoposide aglycone pathway enzymes from mayapple, in tobacco leave
210 sylated polyphenols were more effective than aglycones, polyphenols with (2,1) glycosidic linkages we
211 he methoxy group at the C(4) position on the aglycone portion also appears to add potency and selecti
212 nded wedge-shaped spirocyclic molecule whose aglycone portion is an enantiomer of DDI, which mimics t
214 s the formation of tylactone (1), the parent aglycone precursor of the macrolide antibiotic tylosin.
215 olide and 10-deoxymethynolide, the macrolide aglycone precursors of the antibiotics picromycin and me
216 bonolide (2), the parent 12- and 14-membered aglycone precursors of the macrolide antibiotics methymy
217 ncosamine to the beta-OH-Tyr6 residue of the aglycone, preferentially after GtfB action, to generate
218 and 1,6-conjugate addition at the spiramycin aglycone, proceeds with the inversion of absolute config
219 t, further degradation and transformation of aglycones produce more or less active compounds, dependi
220 This study investigated the stability of the aglycones produced by hydrolysis with beta-glucosidase.
221 own converts chromopyrrolic acid into three aglycone products, K252c, arcyriaflavin A, and 7-hydroxy
222 mportantly, the obtained sample presented an aglycone proportion superior to the reported by other me
223 uring positive ion APCI analysis of limonoid aglycones, protonated molecular ion, [M + H]+, or adduct
224 observed at 919.88 m/z, which represents the aglycone [prymagly+2H](2+) backbone structure common to
226 binding site of ZmGlu1 and form the basis of aglycone recognition and binding, hence substrate specif
234 ursued further modifications to the biphenyl aglycone resulting in significantly improved activity.
238 to crosslinking between the side chains, the aglycone scaffold displays substantial flexibility, impo
242 osides of at least five different triterpene aglycones: soyasapogenol B, soyasapogenol E, medicagenic
243 t saponins based on at least five triterpene aglycones; soyasapogenols B and E, medicagenic acid, hed
244 ties that may play a role in conferring such aglycone specificities were predicted by structural mode
246 erol, hydroxytyrosol, tyrosol and oleuropein aglycone) spiked in Purified Olive Oil (POO) as the lipi
248 is a wedge-shaped spirocyclic molecule whose aglycone structure closely resembles that of the natural
249 compounds were glycosides of four different aglycone structures, of which akebonoic acid and gypsoge
253 bind to the N-terminal domain such that the aglycone substrate's reactive hydroxyl group hydrogen bo
255 GRs can also occur between carbohydrates and aglycones, such as the phenolic compounds present in dai
256 NovM displays activity with variant coumarin aglycones, suggesting it may be a promiscuous catalyst f
259 substrate TDP-L-fucose are also added to the aglycone, the disaccharide and low levels of a fully rec
260 ble to show formation and degradation of the aglycones, the proposed method allows monitoring of the
261 ration of the derivatives of the secoiridoid aglycones; the effect of the temperature on the oxidored
262 nsferase AknS transfers L-rhodosamine to the aglycone to initiate construction of the side-chain tris
263 es examined hydrolyzed LacdiNAc from the TMR aglycone to various degrees, whereas they were less acti
264 library of click-xylosides that have various aglycones to decipher the mechanism of GAG biosynthesis
265 es and the inducible degradation of flavonol aglycones to phloroglucinol carboxylic and phenolic acid
266 ubation with beta-glycosidase, percentage of aglycone (total aglycone/total isoflavones) in SIM isofl
267 a-glycosidase, percentage of aglycone (total aglycone/total isoflavones) in SIM isoflavone extracts i
268 eck for all studies providing isoflavones as aglycones.Twenty-six RCTs (n = 2652) were included in th
269 GtfB efficiently glucosylates vancomycin aglycone using UDP-glucose as the glycosyl donor to form
270 tage biosynthetic precursor to the etoposide aglycone, using an engineered biosynthetic pathway in to
275 y generated cinnamic acid from coumaric acid aglycone was detected in fermented plant material combin
276 earing a 1,4,5-trisubstituted-1,2,3-triazole aglycone was synthesized using a straightforward click/e
281 ol glycosides and increase in the respective aglycones was observed, attributed to enzymatic hydrolys
288 (PNQ) antibiotic lactoquinomycin and related aglycones were found to be selective inhibitors of the s
289 ted glycosides or pelargonidin and petunidin aglycones were identified as the main anthocyanin forms
291 nd luteolin derivatives, in contrast to free aglycones, were not cytotoxic against human lymphocytes
292 lysis 85-91% of total peak areas was terpene aglycone, whereas for acid hydrolysis the area of releas
293 ric digestion, giving hydroxytyrosol and ORP-aglycone, whereas only the superficial ORP was released
294 e vesicles preferentially take up monolignol aglycones, whereas the vacuolar vesicles are more specif
295 lts in a significant rise of the odoriferous aglycones which are direct determinants of the aroma.
296 framework and stereochemical features of an aglycone while simultaneously establishing the site of g
297 eloped a synthetic platform to prepare G-CSF aglycone with the goal of enabling access to native and
298 in the small intestine and appear to absorb aglycones with an efficiency comparable with that of con
299 Monoglycosylated, polyglycosylated, and aglycones with differing polyphenol backbones were studi
300 highly dependent on the sugars linked to the aglycone, with alpha-hederin showing a greater ability t