ライフサイエンスコーパス: ahead

1 Action for Health in Diabetes Mellitus (Look AHEAD).

2 technical constraints, might also be moving ahead.

3 haemic heart disease are challenges that lie ahead.

4 scuss the current limitations and challenges ahead.

5 allowing them to think consciously and plan ahead.

6 3TC/TDF for DOR and FTC/TDF for EFV in DRIVE-AHEAD.

7 so explored to reveal algorithmic challenges ahead.

8 ss, several challenges and opportunities lie ahead.

9 tracking waypoints on the future path 1-3 s ahead.

10 at goal and point out some of the challenges ahead.

11 sure it remains fit for purpose in the years ahead.

12 However, there are challenges ahead.

13 as representative of the potential that lies ahead.

14 d describes the challenges and opportunities ahead.

15 and to look forward to the challenges lying ahead.

16 n, and treatment of lung cancer in the years ahead.

17 to identify the challenges and opportunities ahead.

18 n, and discuss the major challenges that lie ahead.

19 oviding indications on how to move the field ahead.

20 imulate trailing edge retraction in the cell ahead.

21 d therapy, and the challenges that are still ahead.

22 int to opportunities and challenges that lie ahead.

23 ine, participants initially reached straight ahead.

24 ext of what has come before and what may lie ahead.

25 scribes the considerable challenges that lie ahead.

26 l as outline some of the challenges that lie ahead.

27 jet aircraft at distances of more than 50 km ahead.

28 an outlook on the challenges that still lie ahead.

29 al applications and the remaining challenges ahead.

30 key findings, focusing on our global journey ahead.

31 workforce is to meet the challenges that lie ahead.

32 ion on a myriad of challenges that still lie ahead.

33 outlook of the opportunities and challenges ahead.

34 an to obtain specific rewards several trials ahead.

35 by cryo-EM and point to challenges that lie ahead.

36 lessons learned and the challenges that lie ahead.

37 rowing area of research with many challenges ahead.

38 function as well as new directions that lie ahead.

39 mes of research, and call out the challenges ahead.

40 past and only need to be planned one radian ahead.

41 separation causes overwinding of the duplex ahead.

42 vention over 4 years across the DPP and Look AHEAD.

43 ctin filaments to push the front of the cell ahead.

44 e likely than others to succeed in the years ahead.

45 turn our minds to the challenges that remain ahead.

46 acles, and alternative technologies that lie ahead.

47 ORWARD and efavirenz (EFV) in P007 and DRIVE-AHEAD.

48 ll continue to drive gene discovery in years ahead.

49 rable and flexible chemical sensors that lie ahead.

50 roving population health, but challenges lie ahead.

51 plications, and challenges and opportunities ahead.

52 speech from a target talker located straight ahead (0 degrees azimuth) in the presence of four compet

53 (mean difference range: 6.6-11.9 kg in Look AHEAD; 11.5-14.6 kg in DPP; P < 0.0001).

54 nitial weight loss (agreement: 85.0% in Look AHEAD; 87.4% in DPP).

55 nitial weight loss (agreement: 91.6% in Look AHEAD; 90.5% in DPP).Although all of the criteria discri

56 Looking ahead, a deeper understanding of the relationships betwe

57 ; in kg/m(2)) 32 +/- 3] enrolled in the Look AHEAD (Action for Health in Diabetes) trial and randomly

58 study used publicly available data from Look AHEAD (Action for Health in Diabetes; n = 1791) and Diab

59 on/comparison) or with type 2 diabetes (Look AHEAD [Action for Health in Diabetes]; N = 2,014/1,892 i

60 ial weight loss, 7 of 28 comparisons in Look AHEAD and 13 of 28 in the DPP were in high agreement.

61 We reflect on the possibilities that lie ahead and discuss some of the potential pitfalls that mi

62 ensure that eyes are held steady in straight-ahead and eccentric positions of gaze.

63 y of life, clinicians should cautiously move ahead and offer the option of organ preservation to pati

64 plopia, or only rarely for distance straight ahead and reading.

65 t essential task, given the limited timeline ahead and the negative global health and socio-economic

66 toward these goals, consider the challenges ahead, and describe promising applications.

67 immunotherapy-induced irAEs, the challenges ahead, and the opportunities for greater understanding o

68 D printed microfluidics established, we look ahead at trends in 3D printing to gain insights toward t

69 consent" system, donation often does not go ahead because of another issue: their families refuse to

70 e at short time horizons of one or two weeks ahead but model predictions were increasingly unreliable

71 ld be caused not by a disinclination to plan ahead, but by virtue of this ability.

72 hen the world is desperate to know what lies ahead, but caution is warranted regarding the validity a

73 y active helicase that destabilizes the fork ahead by less than 1 k(B)T and back steps very frequentl

74 Therefore, the N-tier ring is pushed ahead by the C-tier ring during CMG translocation, oppos

75 When looking ahead, despite model limitations in simulating mixed lay

76 The DMCM-AHEAD (Diabetes and Lipid Accumulation and Heart Transpl

77 ss of force field direction, in the straight-ahead dimension (F(1,44) = 5.13, p = 0.029).

78 echniques-are highlighted and the challenges ahead discussed.

79 etimes" or worse for reading and/or straight-ahead distance.

80 ctions will be among the challenges that lie ahead during further therapeutic development.

81 Looking ahead, efforts are underway to identify and characterize

82 eriodically every 0.75 s and predictably 2 s ahead, except in 25% of the cases the waypoint at the ex

83 Look-ahead extended farther on journeys to distant goals than

84 ption to amputees, which could chart a route ahead for designing a real-time pain reaction system in

85 ained indicate that there is a bright future ahead for engineering nanomedicines and macroscale mater

86 conclude with a discussion on what might lie ahead for medicinal chemists, biologists, and physicians

87 suggesting a daunting (but stimulating) path ahead for neuroscience more generally.

88 Exciting times lie ahead for pediatric tuberculosis, but much work remains

89 lth and the economy, more difficult days are ahead for psychiatry.

90 additional, unprecedented opportunities lie ahead for public health genomics and the realization of

91 The task that lies ahead for sub-Saharan Africa to achieve elimination is s

92 lications of these findings for what may lie ahead for teenagers as globalization continues to expand

93 Whatever predicament lies ahead for the replication fork, PCNA is there to orchest

94 ditions to avoid and the challenges that lie ahead for these materials in the context of emission red

95 ng average (ARIMA) models, one- to four-week ahead forecasts were generated with two separate data st

96 he first 48 weeks of DRIVE-FORWARD and DRIVE-AHEAD from the DOR groups (DOR/lamivudine [3TC]/tenofovi

97 The neuroscience field is steaming ahead, fueled by a revolution in cutting-edge technologi

98 Looking ahead, further genetic discoveries are expected to lead

99 Looking ahead, future challenges and opportunities that will sig

100 suring 14-25 prism diopters (PD) in straight-ahead gaze at distance fixation.

101 ism diopters [pd] hyperdeviation in straight-ahead gaze) and 4 asymmetric.

102 ad of unexplored applications that still lie ahead in cancer research and medicine.

103 [1-3], such as when we plan one or two moves ahead in chess.

104 ividual (e.g., hard work) factors in getting ahead in society (i.e., opportunity beliefs).

105 ss the opportunities and challenges that lie ahead in targeting meta-organismal endocrinology for CVD

106 mmentary on the opportunities and challenges ahead in this growing field.

107 ajectories, we predict 80% of patient events ahead in time.

108 ins made and significant challenges that lie ahead in trying to accurately delineate their identities

109 the progresses made and highlight challenges ahead in vaccines and the science behind them.

110 Challenges ahead include a better understanding of rare variants an

111 DRIVE-AHEAD is a phase 3, double-blind, non-inferiority trial.

112 Look AHEAD is a randomized, controlled trial to determine the

113 The main challenge on the road ahead is to harness bigger health care data in ways that

114 or human subjects, allowing sponsors to move ahead more quickly with the development of new agents.

115 from the Action for Health in Diabetes (Look AHEAD, n=4760; 2001-12).

116 rials: DRIVE-FORWARD (NCT02275780) and DRIVE-AHEAD (NCT02403674).

117 e III: DRIVE-FORWARD [NCT02275780] and DRIVE-AHEAD [NCT02403674]).

118 urrent reproduction with their own condition ahead of a challenging migration and future reproduction

119 Stress localization ahead of a slip band blocked by a grain boundary is meas

120 d of changes in high-latitude NADW formation ahead of abrupt climate changes recorded in Greenland ic

121 nges associated with the future developments ahead of agarose-based biomaterials in the realm of adva

122 ositions behind to those signaling positions ahead of an animal's current location [11, 12].

123 This response is particularly prominent ahead of an ictal wavefront.

124 can be made as early as three to four months ahead of an outbreak.

125 breaks and then reforms histone-DNA contacts ahead of and behind it, respectively.

126 influenza-like illness 1 wk, 2 wk, and 3 wk ahead of available data and when forecasting the timing

127 the method forecasts a danger over one month ahead of blockage.

128 A when the number of genes in a cell doubles ahead of cell division?

129 ration, and show Csm3/Tof1 "grip" duplex DNA ahead of CMG via a network of interactions important for

130 , as recently proposed by French authorities ahead of COP21 in the 'four per mil' initiative, is nota

131 inal vasculature grows towards the periphery ahead of differentiated astrocytes, but behind astrocyti

132 NA template structures and G-rich sequences, ahead of diverse reverse transcriptases can be strong st

133 icacious antibiotics available to the public ahead of epidemic resistance.

134 s well, toward designing inhibitors one step ahead of evolution to counter resistance with more intel

135 is widely accepted that column technology is ahead of existing chromatographic instruments.

136 ng methods to predict thermostable mutations ahead of experiments.

137 while viral latency genes are downregulated ahead of expression of the viral latent-to-lytic switch

138 of antibody leads, and points to ways to get ahead of future pandemics.

139 methodology can produce predictions one week ahead of GFT's real-time estimates with comparable accur

140 e meaningful "nowcasts" of disease incidence ahead of healthcare-based estimates, with most successfu

141 A visionary Darwinian ahead of his time, George C.

142 teins, their interactions, and the challenge ahead of integrating PTMs into an understanding of prote

143 arting slightly behind the animal and ending ahead of it.

144 d locations near the postsynaptic neuron and ahead of its preferred direction.

145 y downregulated in Krt16-null paw skin, well-ahead of lesion onset, and is paralleled by pleiotropic

146 tests by date of specimen collection, 1-4 d ahead of local hospital admissions and 6-8 d ahead of SA

147 e useful to public health services, not only ahead of mass gatherings, but also before the peak dengu

148 0 drones would be required to deliver an AED ahead of median 911 response times by 3 minutes.

149 d by deoxyuridine conversion to abasic sites ahead of nascent lagging strand DNA synthesis and subseq

150 assembled in mitotic prophase, significantly ahead of nuclear pore disassembly.

151 hat can estimate infectious disease activity ahead of official healthcare-based reports, at relevant

152 to plan the allocation of limited resources ahead of ongoing outbreaks.

153 Ahead of online mass spectrometric analysis, field asymm

154 ving, with the epidemiology-based literature ahead of potential biological mechanisms that might expl

155 ting that postsynaptic alterations may occur ahead of presynaptic deficits.

156 Ahead of Print article withdrawn by publisher.

157 American Heart Association," which published ahead of print August 13, 2015, and appeared in the Sept

158 ral Arterial Events," which published online ahead of print September 8, 2015, and appears in the Nov

159 DLINE (including MEDLINE In-Process and Epub Ahead of Print), Embase and the Wiley search platform in

160 [Epub ahead of print.] 32371401.

161 [Epub ahead of print].

162 growth factor) is expressed dynamically just ahead of progenitor outgrowth in decaying branches.

163 ads onto the procentriole during interphase, ahead of Rcd4 and before mitosis.

164 for planning foot placement nearly two steps ahead of reaching the obstacle.

165 complexes associated with un-replicated DNAs ahead of replication forks into cohesive structures behi

166 y remove positive supercoils that accumulate ahead of replication forks.

167 -azacytidine does not increase Xi expression ahead of reprograming, but instead reveals a second cadr

168 tochastic Xi expression in human fibroblasts ahead of reprograming.

169 oV-2 RNA concentrations in sludge were 0-2 d ahead of SARS-CoV-2 positive test results by date of spe

170 ahead of local hospital admissions and 6-8 d ahead of SARS-CoV-2 positive test results by reporting d

171 PSs just ahead of SLE were associated with hyperpolarizing potent

172 y, we demonstrate that dependence can evolve ahead of specialized structures (e.g., bacteriocytes), a

173 However, 2 basic information gaps loom ahead of such a study: the development of robust, valid,

174 2), initially presented with ocular symptoms ahead of systemic symptoms (p < 0.001), and corneal edem

175 and initially presented with ocular symptoms ahead of systemic symptoms (p = 0.007) were the signific

176 This pilot recruited ahead of target; 100 patients were recruited within nine

177 listic forecasts of dengue risk three months ahead of the 2014 World Cup in Brazil.

178 guard allows the pathogen to remain one step ahead of the acquired immune response, enabling persiste

179 accurately predict future actions or events ahead of the act itself.

180 the neural/epidermal (Ne/Epi) boundary just ahead of the advancing zipper.

181 he extent to which theta sequences projected ahead of the animal's current location varied on a momen

182 e subdivision of the deformed microstructure ahead of the boundary plays the dominant role.

183 The polarity of the N-tier ahead of the C-tier places the leading Pol epsilon below

184 tic deflection of the structure was observed ahead of the compaction of the lattice, while no elastic

185 crack arrests stably, and thus the material ahead of the crack front continues to sustain load, ther

186 on of the maximum deviator stress is tracked ahead of the crack tip on the experimental concrete samp

187 represented relatively long paths extending ahead of the current location.

188 exes tether to and degrade the peptidoglycan ahead of the engulfing membrane, generating an irregular

189 and show that stromal gene signature changes ahead of the epithelial gene signature as prostate cance

190 The MCM motor of the CMG helicase powers ahead of the eukaryotic replication machinery to unwind

191 proposed that the overwinding that builds up ahead of the fork could force it to swivel and diffuse t

192 acteria, DNA gyrase and topoisomerase IV act ahead of the fork to keep DNA underwound.

193 ng away to aid nucleoprotein barrier removal ahead of the fork, another assisting PriC-dependent relo

194 n contexts that inhibit topoisomerase action ahead of the fork, including stable protein-DNA fragile

195 ation elongation by driving DNA supercoiling ahead of the fork, where supercoiling is more efficientl

196 rential resolution of DNA topological stress ahead of the fork.

197 replication elongation to dissipate torsion ahead of the forks.

198 ature, CO2 , and nitrogen deposition decades ahead of the global average, such that biological respon

199 he TPRE mechanism, and (iii) the segregation ahead of the growing Si twins, inducing a solute entrain

200 ould not be perturbed by a late PHC (<=20 ms ahead of the His) due to the retrograde His conduction t

201 the profile of paediatric malaria admissions ahead of the introduction of RTS,S/AS01 vaccine.

202 ical profile of pediatric malaria admissions ahead of the introduction of the RTS,S/AS01 vaccine.

203 h regions located between -7585 and -5550 bp ahead of the main transcription start site and via an NF

204 The daughter centriole invariably migrated ahead of the MC from the center to their respective peri

205 atic heating by shallow and congestus clouds ahead of the MJO center, enhancing the Kelvin-Rossby wav

206 es, boutons tuned to regions of visual space ahead of the mouse showed enhancement of responses.

207 and looked 6% longer and 6% more frequently ahead of the obstacle.

208 A bright future is ahead of the organometallic chemist, thanks to these nov

209 In principle, either tier could translocate ahead of the other during movement on DNA.

210 heterohexamer, unwinds the DNA double helix ahead of the other replication machinery.

211 financial resources to drive its development ahead of the outbreak, point-of-care Ebola tests support

212 The resulting piling up of surface steps ahead of the oxide growth front progressively impedes th

213 esults by date of specimen collection, 0-2 d ahead of the percentage of positive tests by date of spe

214 vided the helicase is located one nucleotide ahead of the primer-end.

215 for targets displaced to new locations just ahead of the prior path, with suppression elsewhere in t

216 he population, such that place-field centers ahead of the rat are sequentially activated in the order

217 weekly ILI predictions for up to four weeks ahead of the release of CDC's ILI reports.

218 ity through resolution of G4 structures both ahead of the replication fork and on the lagging strand

219 This is achieved by topoisomerase action ahead of the replication fork or by fork rotation and su

220 artemisinin-piperaquine and its determinants ahead of the results of the overall trial, which will be

221 nucleation and growth occur upon heating and ahead of the scanning laser focus.

222 focusing of strains yields the material just ahead of the singularity, allowing it to propagate, leav

223 of growing hyphae during vegetative growth, ahead of the Spitzenkorper, and is required for polarize

224 at drives the assembly of the efflux complex ahead of the transcription activation of the cus operon

225 some cases, EWIs were detected considerably ahead of the transition.

226 activating myosin II along Ne/Epi junctions ahead of the zipper and inhibiting myosin II along newly

227 curate prediction of intended movements well ahead of their execution, with an area under the receive

228 the position of moving upper limbs slightly ahead of their real position but only when the anticipat

229 he founders of the Dutch hypothesis were far ahead of their time, and we can learn from their insight

230 ble of circumnavigating dead (trapped) cells ahead of them by choosing a serpentine path.

231 hen in contact with glial precursors growing ahead of them.

232 antages and outstanding challenges which lie ahead of this technology are discussed.

233 ble objectives have reached the 2020 targets ahead of time (n=14) or are on track to meet the targets

234 sion making based on predictions a few weeks ahead of time but not longer, reflecting the high level

235 uction in incidence by 2030 may be reachable ahead of time in this population.

236 tic resonance imaging scanner, premix of tPA ahead of time, initiation of tPA in brain imaging suite,

237 tive cues when the demanded action was known ahead of time.

238 management options to minimize yield losses ahead of time.

239 ed us to predict spontaneous strategy shifts ahead of time.

240 dicting the 4 clustered regimes up to 5 days ahead of time.

241 g and predicting these clusters up to 5 days ahead of time; (2) Use this approach to label thousands

242 e interval 0.72-0.82 when ordered > 180 days ahead of time; odds ratio = 0.90, 95% confidence interva

243 ease activity in five recent outbreaks weeks ahead of traditional surveillance methods.

244 Ahead of upcoming larger genome-wide association studies

245 ncient individual known as "Shuka Kaa" ("Man Ahead of Us") recovered from the On Your Knees Cave (OYK

246 lized, which will be enabled by the research ahead of us.

247 basis for progressing navitoclax into trials ahead of venetoclax in other subgroups.

248 ehavior of emerging disease outbreaks in, or ahead of, real-time could help healthcare officials bett

249 induced mixing, led to significant and rapid ahead-of-eye-centre cooling (at least 6 degrees C and up

250 uoy similarly revealed significant and rapid ahead-of-eye-centre cooling during Typhoon Muifa (2011).

251 Historical buoys from 1985 to 2015 show that ahead-of-eye-centre cooling occurred beneath all 11 trop

252 ," "often," or "always" in distance straight ahead or reading positions on the Diplopia Questionnaire

253 nce that participants in our experiment plan ahead over two consecutive, inter-dependent helping oppo

254 Look AHEAD participants included in this report were 3,845 ov

255 INTERPRETATION: Look AHEAD participants with moderately or poorly controlled

256 Looking ahead, patient centric functional screening in primary c

257 E) and after (POST)implementation of the Bed Ahead policy.

258 A "Bed Ahead" policy was instituted at an urban level 1 Trauma

259 In the months ahead, policy makers are likely to face difficult choice

260 We estimate one-month-ahead prevalence in a unique 22-years prospective region

261 en approach that reliably produces one-month-ahead prevalence prediction within a densely populated a

262 0 minutes each) or CCBT using the "Good Days Ahead" program.

263 th type 2 diabetes were enrolled in the Look AHEAD randomised controlled trial, of whom 4901 were inc

264 before and after subjects performed straight-ahead reaches grasping a robotic manipulandum.

265 ART model successfully predicted the 3-month-ahead reductive dechlorination potential with 75.8% and

266 commentary on the opportunities and barriers ahead regarding the integration and translation of curre

267 Looking ahead, some of these neuropeptides may have effects that

268 vespertilionids, but ensonifying objects far ahead suggesting more clutter.

269 Finally we outline the challenges ahead that will be fundamental to overcome if the ultima

270 However, the owl stayed ahead, the buzzard stayed on, and the falcon stayed behi

271 While the long road of translation lies ahead, the path to meaningful clinical progress has neve

272 ion flavours, can be predicted up to 3 years ahead, thus exceeding the predictive skill of current tr

273 sive signal to the trailing edge of the cell ahead to communicate directional information between nei

274 cardiovascular trials, indicating much work ahead to continue recent success.

275 it is clear that there are major challenges ahead to develop new vaccines for difficult-to-target pa

276 memory, primarily at the DNA level, and look ahead to discuss their potential implications in reward

277 xt of heterobifunctional molecules and looks ahead to new possibilities presented by these results.

278 Finally, we look ahead to persistent challenges in the application of net

279 Furthermore, looking ahead to potential therapeutic strategies encompassing i

280 Although challenges lie ahead to reach clinical fruition, the unique mechanical

281 n criteria, and previous experience, looking ahead to the chance of a cure for these disorders.

282 ngs, highlight recent developments, and look ahead to the changes in clinical practice that will like

283 he challenges and the opportunities that lay ahead to the development of efficacious and nontoxic PAI

284 Finally, we look ahead to the remaining challenges associated with curren

285 he hippocampus and, finally, attempt to look ahead toward novel therapeutics for brain aging.

286 Participants from the Look AHEAD trial (Action for Health in Diabetes) without prev

287 Adults from the Look AHEAD trial (Action for Health in Diabetes) without prev

288 ts with type 2 diabetes mellitus in the Look AHEAD trial, the intensive lifestyle intervention did no

289 The Action for Health in Diabetes (Look AHEAD) trial investigated whether long-term cardiovascul

290 eight loss or regain within the DPP and Look AHEAD trials, directly or via interactions with lifestyl

291 On arrival at goals, however, look-ahead was similar regardless of where the animal began i

292 By predicting ahead, we can give our brains a "head start," so that la

293 Looking farther ahead, we envision direct linkages between aggregate exp

294 Looking ahead, we highlight two key knowledge gaps that continue

295 Looking ahead, we propose systems genetics as a complementary ap

296 n vegetation productivity two to six seasons ahead which enables national governments and farmers for

297 e evidence that birds can plan several moves ahead while using tools.

298 cholesterol synthesis, and no doubt the road ahead will reveal further twists and turns for this fasc

299 , which we find can also be predicted months ahead with a significant skill of 0.56.

300 The CIT for transplants that went ahead with a virtual XM was 3 hours shorter than those r