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1 effect on extravasation of 70-kDa dextran or albumin.
2 fibrinogen mass is 168% greater than that of albumin.
3 ned albumin supplements such as bovine serum albumin.
4 ate constant 0.563-fold smaller than that of albumin.
5 and high molecular mass dextran molecules or albumin.
6 two storage proteins - vicilin and a 21 kDa albumin.
7 emonstrated for a prototypical large protein-albumin.
8 was removed and replaced with 5% human serum albumin.
9 in a protein digest mixture of bovine serum albumin.
10 cles in ethanolic solutions and bovine serum albumin.
11 BCs when delivered as part of a complex with albumin.
12 e 3/4 hepatic encephalopathy, WBC count, and albumin.
13 hydrolysis and precipitation of bovine serum albumin.
14 h artificial urine spiked with 30-300 ppm of albumin.
15 to exhibit high binding affinities to serum albumin.
16 alorimetry that JMS-053 binds to human serum albumin.
17 that all drug would be bound specifically to albumin.
18 fetal bovine serum (FBS) identified as serum albumin.
19 VEGF-induced BRB permeability to Evans Blue-albumin.
20 d many mesothelin-positive cells coexpressed albumin.
21 tion increase due to their interactions with albumin.
22 fragment specific for mouse and human serum albumin.
23 capacity, transferrin saturation, and serum albumin.
24 s that is based on similarities among the 2S albumins.
25 /l p < 0.001 (95% CI - 43.64 to - 23.55) and albumin 0.29 g/dl p < 0.001 (95% CI - 0.42 to - 0.15); P
27 T-rich interaction domain 1A (ARID1A) (13%), albumin (11.4%), apolipoprotein B (APOB) (9.4%), and AXI
29 ment, were neutropenia (48 [15%]), low serum albumin (33 [10%]), weight loss (29 [9%]), and anaemia (
31 <5 L paracentesis were randomized to receive albumin (8 g/dL of ascitic fluid; n = 40) or no albumin
33 binding of unconjugated bilirubin (B(T) ) to albumin (A) and validate their molar concentration ratio
36 RAR activity was repressed by acetylcholine, albumin, aldosterone, angiotensin II, high glucose, cisp
39 gn a bifunctional molecule with affinity for albumin and a serum protein involved in cholesterol meta
40 of beta(2) -m and RBP4 differs from that of albumin and alpha(1) -m in their sensitivity to changes
41 ctional urinary excretion of 0.025%, whereas albumin and alpha(1) -microglobulin (alpha(1) -m) are re
43 he ability to detect miRNA-21 in human serum albumin and bovine serum albumin was almost identical to
44 eening tools, length of hospital stay, serum albumin and cholesterol concentrations, lymphocyte count
47 We study exchange of two blood proteins, albumin and fibrinogen, adsorbing to and competitively d
49 s closely related to the history of ascites, albumin and hemoglobin but not to tumour load or to resp
51 bining elevated hsCRP and ESR with low serum albumin and iron], and serum interleukin (IL) 1beta were
52 high plasma levels; similarly, FcRn recycles albumin and is the portal of entry for enteric cytopathi
54 Increased sodium and magnesium and decreased albumin and lactate levels were detected in animals euth
55 m tomato and mustard seeds, we identified 2S albumin and non-specific lipid transfer proteins (nsLTP)
59 time of hospital admission, serum levels of albumin and sodium, and white blood cell count, to ident
61 sitivity C-reactive protein, fibrinogen, and albumin), and bone mineral metabolism (25-hydroxyvitamin
62 ats exhibited increased permeability of FITC-albumin, and a single norrin injection restored BRB prop
64 reby increased affinity for lipid particles, albumin, and other plasma proteins by lipid-conjugation
65 at dialysate electrolyte composition, plasma albumin, and plasma total CO2 accurately predict the mea
66 ction with plasma biomacromolecules, such as albumin, and self-aggregation at high concentrations and
68 airment (aOR 5.14, 95%CI 2.65-9.97), and low albumin (aOR 1.06, 95%CI 1.02-1.09, increase per g decre
70 eriments provide strong evidence that the 2S albumins are the most important allergens in peanuts for
72 lforhodamine b, zidovudine, and bovine serum albumin as model hydrophilic drugs, we found tapped coat
74 In summary, site-specific loading of drug to albumin at 1:1 ratio allowed the conjugate to better mai
75 fied by X-ray crystallography in human serum albumin at drug site 3, which is also known as subdomain
76 osphatase [ALP], total bilirubin [TBIL], and albumin) at three time points (preinfection baseline, ad
77 es the mechanistic basis for exploitation in albumin-based drug designs engineered to optimise this p
79 we have investigated the use of MRI-visible, albumin-based nanoclusters for noninvasive, localized an
80 ratory-related (platelet count < 50 x 109/L, albumin below normal, LDH above normal at time of admiss
82 mized affinity-modifying group and optimized albumin binders to maximize the tumor-to-kidney absorbed
83 The optimized affinity-modifying group and albumin binders were combined, and the resulting derivat
84 bearing various affinity-modifying groups or albumin binders were synthesized and evaluated by PET/CT
85 this purpose, two different PBs derived from Albumin Binding Domain (ABDwt) of streptococcal protein
89 ogs and ~70 h in man is achieved by a strong albumin binding, and by lowering the insulin receptor af
90 tested the effect of adding a streptococcal albumin-binding domain (ABD) and a llama single-domain a
91 ach is to attach drug leads to the G-related albumin-binding domain (ABD) to bind albumin and evade c
94 -Gly and N-(4-(p-methoxyphenyl)butanoyl)-Gly albumin-binding motifs generated HTK03121 and HTK03123,
95 igher in vivo MR signal enhancement from the albumin-binding probe (p = 0.047) and a smaller nonenhan
97 of magnetic resonance imaging (MRI) with an albumin-binding probe to assess changes in vascular perm
98 ove the therapeutic index of current in situ albumin-binding prodrugs, we developed albumin-drug conj
102 ency virus status with CD4 count, age, serum albumin, body mass index, and pre-existing hearing loss.
103 Meanwhile, the introduction of bovine serum albumin (BSA) and antibody (Ab) enhanced the dispersity
104 avior of two model proteins- i) bovine serum albumin (BSA) and ii) beta-galactosidase (beta-gal), was
105 ydrolyzed iron oxide-associated bovine serum albumin (BSA) and the factors that affected the proteoly
106 with a 4-plex labeled sample of bovine serum albumin (BSA) and yeast lysates mixed at different ratio
107 L) after passive adsorption and bovine serum albumin (BSA) as a blocking agent generated a moderate s
110 re collected from a solution of bovine serum albumin (BSA) digested by trypsin as an enzymatic model
112 portant roles in the ability of bovine serum albumin (BSA) to form stable nanostructures with bioacti
113 coside (CYG) through binding to bovine serum albumin (BSA) was investigated at pH 3.0 using atomic fo
115 report, a stepwise unfolding of bovine serum albumin (BSA) with guanidine hydrochloride (GuHCl) has b
117 lbumin hydrogels has focused on bovine serum albumin (BSA), leaving human serum albumin (HSA) compara
120 ing small (glycerol) and large (bovine serum albumin; BSA) analyte molecules, indicating that the hyd
121 ectiveness to reduce wine turbidity than egg albumin but modified in different way the phenolic compo
122 ex vivo ensures complete drug binding to the albumin carrier and achieves excellent antitumor efficac
123 mimetic nanoparticles (cationic bovine serum albumin (CBSA) conjugated siS100A4 and exosome membrane
125 tion yield (total proteins, helianthinin and albumins), chlorogenic acids covalently bound to protein
126 ) retained the native secondary structure of albumin compared to conjugate with a higher DAR of 3 (AL
127 irect imaging of the transport of Evans blue-albumin complex in brains of rats subjected to recurrent
128 eport the crystal structures of equine serum albumin complexed with four NSAIDs (ibuprofen, ketoprofe
129 re noted for inflammatory (total protein and albumin concentrations) and hepatic (ALT, AST) parameter
130 debridement, inflammatory (total protein and albumin concentrations) and hepatic (AST) parameters ret
132 uation) trial in patients with T2DM, urinary albumin-creatinine ratio >300 mg/g, and estimated glomer
134 provided GWAS summary data for eGFR, urinary albumin-creatinine ratio (UACR), BUN, and serum urate.
135 4 or 45-59 ml/min per 1.73 m(2) with urinary albumin/creatinine (ACR) >=50 mg/g and serum bicarbonate
137 diabetes duration, waist/hip ratio, urinary albumin/creatinine ratio (ACR) and fasting C-peptide.
140 ase and no history of gout who had a urinary albumin:creatinine ratio of 265 or higher (with albumin
141 .7 ml per minute per 1.73 m(2); median urine albumin:creatinine ratio, 716.9; mean serum urate level,
144 the enrichment step from spiked bovine serum albumin digests were >80% for the commercial Fe-IMAC kit
145 er injection (65.2% vs 35.0%, P = 0.05), and albumin dissolvent (68.1%) compared to fresh frozen plas
146 re reliably identified with ICG dose >=1 mg, albumin dissolvent, post-injection lung ventilation, rad
147 factor in fetal bovine serum, identified as albumin, does not interfere with the catalytic activity
149 situ albumin-binding prodrugs, we developed albumin-drug conjugates with a controlled loading that a
150 sted source of amino acids; a role driven by albumin engagement with its cognate cellular recycling n
151 f B(T) correlated inversely to the bilirubin-albumin equilibrium association binding constant (R(2) =
153 Glomerular filtration rate (GFR) and urinary albumin excretion rate (UAER) are used to diagnose and c
155 f glomerular filtration rate (GFR) and urine albumin excretion, and kidney injury was evaluated by hi
157 ssion of specific hepatic markers as well by albumin expression and secretion, is severely compromise
158 elded 46.83% and 59.16% of total protein and albumin extraction yield, 1.730 and 1.998 mg.g(-1) of ch
161 similarities with epitopes of allergenic 2S albumins from peanut (Ara h 2 and 6) and Brazil nut (Ber
162 immunity measures (serum IgG, serum protein, albumin, globulin and total protein concentrations, tota
163 ease, corresponds to a 3.5-fold elevation in albumin glomerular filtration, supporting the use of mic
164 reference molecules (dopamine, bovine serum albumin, glucose and elongated peptide) was negligible.
165 lla asiatica phenolics (CAP) on bovine serum albumin glycoxidation in a BSA-glucose model in vitro.
166 re frequent in the no-albumin group than the albumin group (70% versus 30%; P = 0.001), with higher i
168 ents with score 0 (baseline LSM <= 17.3 kPa, albumin >4.2 g/dL, and 1-year DeltaLSM > 25.5%) versus 5
170 RA in rescuing RA/RAR activity repressed by albumin, high glucose, angiotensin II, aldosterone, cisp
171 d was associated with older age, lower serum albumin, higher blood neutrophil counts, and greater pre
173 54, P = 0.02), diabetes (HR 2.39, P = 0.01), albumin (HR 0.35, P = 0.001), and GRS score >0.597 (HR 2
174 8; 95% CI = 1.2-2.6; P < 0.01) and low serum albumin (HR = 2.1; 95% CI = 1.5-2.9; P < 0.01) were sign
175 s the target biomarker proteins (human serum albumin (HSA) and human immunoglobulin G (HIgG)) and ach
176 and kinetics of binding between human serum albumin (HSA) and resveratrol (RES) or its analog (RESAn
177 to investigate the potential of human serum albumin (HSA) as a solubilising agent/drug delivery vehi
180 icle (SPNP) based on polymerized human serum albumin (HSA) equipped with the cell-penetrating peptide
181 thione S-transferase pi (hGSTP), human serum albumin (HSA), and bovine serum albumin (BSA) as model t
182 expressed extracellular protein, human serum albumin (HSA), inhibits alphaS oligomer (alphaS(n)) toxi
187 iked with microproteinuria concentrations of albumin, immunoglobulin, and hemoglobin, giving a predic
188 educed ESA requirements, and increased serum albumin in patients on hemodialysis with inflammation an
190 solutions in a complex matrix (bovine serum albumin in phosphate buffered saline) is also demonstrat
192 on of the biophysics of binding of an ABD to albumin in solution could shed light on this question.
195 umulation in tumours could reflect a role of albumin in transport of endogenous nutrient cargos requi
197 of the physicochemical properties of the 2S albumins in peanuts, tree nuts, and sesame seeds will en
202 ons in the CP without inducing extravascular albumin leakage or major leukocyte infiltration into the
204 ty (area under the curve >0.70), as were low albumin level, lymphocyte count, monocyte count, and rat
207 significantly with urinary nephrin, IgG and albumin levels, suggesting suPAR as a pathophysiological
208 prevent SS1P-mediated kidney damage, reduce albumin loss in urine, and alleviate capillary leak synd
209 lnutrition was measured using serum markers (albumin <3.5 g/dL) as well as body mass index (BMI) as a
212 The reversible binding of JMS-053 to serum albumin may serve to increase JMS-053's plasma half-life
213 w the structural similarities among their 2S albumins may account for observed clinical cross-reactiv
214 umin:creatinine ratio of 265 or higher (with albumin measured in milligrams and creatinine in grams)
215 a urinary albumin-to-creatinine ratio (with albumin measured in milligrams and creatinine measured i
216 nephrotic range proteinuria (NNRP) and serum albumin measurements in relation to PLA2R-AB status.
217 f the particle supernatant with bovine serum albumin mitigates the negative effects of free or bound
218 er, ion mobility resolution for bovine serum albumin (MW ~ 68 kDa) is less than ~20, which arises fro
219 umin (8 g/dL of ascitic fluid; n = 40) or no albumin (n = 40) and serially followed to detect PICD.
221 ER stress with 4-PBA decreased the effect of albumin on Klotho protein levels without altering mRNA l
222 ore sensitive markers of PT dysfunction than albumin or alpha(1) -m, and suggest that reduced PT sodi
225 d to DMSO/phosphate buffered saline (PBS) or albumin/PBS solutions in an in vitro M. tuberculosis-inf
227 ts, faecal calprotectin, C-reactive protein, albumin, platelet count, 25(OH) vitamin D, or 1,25(di-OH
229 of three Charged Model Molecules (CMMs, egg albumin, polyphenols and riboflavin) was carried out to
232 nctional analyses performance (i.e. urea and albumin production, cytochrome P450 activity and inducti
233 m whole blood, volume metering, depletion of albumin, protein digestion with trypsin, and stabilizati
236 ulting albumin-drug conjugate with a drug to albumin ratio (DAR) of 1 (ALDC1) retained the native sec
238 n, all P < .05), and an increased CSF:plasma albumin ratio, a marker of blood-brain barrier breakdown
240 ith mechanistic data suggesting hFcRn-driven albumin recruitment for increased cellular growth that h
241 tal Fc receptor (FcRn) that mediates IgG and albumin recycling also participates in cellular response
243 (sucrose, dopamine, starch, and bovine serum albumin), resulting in negligible cross-reactivity excep
244 spleen of a systemically administered serum albumin (SA)-IL-4 fusion protein leads to higher efficac
246 asmonic construct consists of a bovine serum albumin scaffold with approximately 210 IRDye 800CW fluo
247 y 1:400 horse radish peroxidase/bovine serum albumin, sensitivity to 100 attomoles, recovery 89.51%,
248 EsTo) consists of nine variables: bilirubin, albumin, serum alkaline phosphatase (SAP) times the uppe
249 ctures in the organoid displayed dextran and albumin size selectivity across their glomerular filtrat
250 sing IDA in intact and digested bovine serum albumin solutions using the TCN (98 and 100%, respective
252 uted at technetium 99m macroaggregated human albumin SPECT/CT was associated with better overall surv
255 h (DeltaB(pp) = 24 mG), a lower affinity for albumin than Finland trityl, and a high aqueous solubili
257 was removed and replaced with 5% human serum albumin to reduce haemoglobin concentration (n = 8).
261 lomerular filtration rate (eGFR) and urinary albumin-to-creatinine ratio (ACR), with cancer incidence
262 We also identified 2 known loci for urine albumin-to-creatinine ratio (BCL2L11 rs116907128, P=5.6x
263 dded kidney measures was cysC-eGFR and urine albumin-to-creatinine ratio (DeltaC=0.019 [95% CI, 0.015
264 underpinnings with the exception of urinary albumin-to-creatinine ratio (Rg = 0.64; SE = 0.22; P = 0
265 llele frequency=0.01, P=1.6x10(-8)) or urine albumin-to-creatinine ratio (rs527493184 at ZBTB16, mino
266 lementary prognostic value of baseline urine albumin-to-creatinine ratio (uACR) and plasma soluble tu
267 learance; albuminuria was estimated by urine albumin-to-creatinine ratio (UACR); and M/I was estimate
269 uded patients with type 2 diabetes and urine albumin-to-creatinine ratio 30 to 5000 mg/g and an estim
270 been assessed in 2006 to 2010 with the urine albumin-to-creatinine ratio and estimated glomerular fil
271 timated glomerular filtration rate and urine albumin-to-creatinine ratio in up to 12 207 Hispanics/La
272 diabetic retinopathy, or they had a urinary albumin-to-creatinine ratio of 300 to 5000 and an eGFR o
273 =9.3x10(-11)) and validated 8 loci for urine albumin-to-creatinine ratio previously identified in the
276 y measures (creat-eGFR, cysC-eGFR, and urine albumin-to-creatinine ratio) led to significant improvem
281 ionally, nephrotic-range albuminuria with an albumin-to-creatinine-ratio (ACR) >220 mg/mmol was a sig
282 ween log(ACR) and log(PCR), with the implied albumin-to-protein ratio increasing from <30% in normal
284 polarized HLCs secrete cargo directionally: Albumin, urea, and lipoproteins are secreted basolateral
285 examine the binding of an ABD to human serum albumin using isothermal titration calorimetry and asses
287 E (MMAE) was conjugated ex vivo to Cys34 of albumin via a cathepsin B-sensitive dipeptide linker to
289 ted for growth in medium where extracellular albumin was the obligate source of the essential amino a
290 A mass balance model based on bovine serum albumin-water (D(BSA/w)) and liposome-water distribution
294 elet-derived growth factor AB [PDGF-AB], and albumin) were measured in fresh and lyophilized serum.
296 A3 binds to at least one site on human serum albumin, which is likely to extend the compound's plasma
297 acute kidney injury (AKI) were randomized to albumin with infusion of terlipressin (2-12 mg/day; n =
298 inogen has a higher affinity for SWCNTs than albumin, with a fibrinogen on-rate constant 1.61-fold gr
299 arness the intrinsic transport properties of albumin yet improve the therapeutic index of current in
300 al covariates such as performance status and albumin, yielding AUCs as high as 0.84-0.85 for the pred