ライフサイエンスコーパス: alkalinize

1 They died rapidly unless alkalinized.

2 V-H(+)-ATPase (bafilomycin A(1)), or to the alkalinizing agent NH(4)Cl.

3 bafilomycin A1, enhanced curvature, whereas alkalinizing agents disrupted gravitropic bending.

4 ey also provide evidence that treatment with alkalinizing agents, together with antibiotics, may prov

5 he bacterial pathogen Pseudomonas aeruginosa alkalinized and condensed lysosome-related organelles.

6 o, the pfk1Delta and pfk2Delta vacuoles were alkalinized and the cytosol acidified, suggestive of imp

7 irway epithelia more rapidly and effectively alkalinized ASL in response to a luminal acid challenge

8 Treating epithelia with IL-17 plus TNFalpha alkalinized ASL pH to ~7.0, increased paracellular HCO(3

9 clinically approved CFTR modulators further alkalinized ASL pH.

10 pool was also triggered when the cytosol was alkalinized by removing the weak acid acetate.

11 lity to neutralize the acid pH because other alkalinizing compounds similarly inhibit escape and MNGC

12 high actin turnover rates without having to alkalinize cytosol, which would affect many biochemical

13 Activation of NCAM expression in alkalinized dissociated cells was identical to that obse

14 cted simultaneous presence of acidifying and alkalinizing disturbances, many of them grave.

15 ded pH reporters, astrocytes are observed to alkalinize during epileptiform activity, whereas neurons

16 and noggin was observed at stage 11 in both alkalinized ectoderm and the newly induced neural plate,

17 osphorylated protein detected in induced and alkalinized ectoderm were greatly reduced or absent in u

18 rior neural inducer noggin were expressed in alkalinized ectoderm, while the more posterior neural ma

19 er-perfused recipient cells has a favourable alkalinizing effect and supplies substrate for oxidative

20 The alkalinizing effect of cyanide salts and the problems en

21 The alkalinizing effect of imidazole and chloroquine was sho

22 oth the acidifying effect of protein and the alkalinizing effect of potassium (organic anions), NEAP

23 chemical base) from the spheroid core had an alkalinizing effect on the rim, producing therein a mili

24 duction appear to be minor compared with the alkalinizing effects of fruits and vegetables.

25 wth factor receptor (EGFR) and concomitantly alkalinizes endosomes, presumably by binding to the 16-k

26 ntrast, removal of serosal Cl- caused pHi to alkalinize in both normal and CF epithelia.

27 , we find the intraluminal pH in Golgi to be alkalinized in GGA1-null cells.

28 Thus, E5 does not uniformly alkalinize intracellular compartments, and its C-termina

29 Addition of NH4Cl, which is expected to alkalinize intraorganellar pH, did not alter intraorgane

30 Subsequently, as V. cholerae alkalinizes its environment in late stationary phase, th

31 recycling endosomes, where it significantly alkalinizes luminal pH, elevates uptake of transferrin a

32 ving caveolin-1 protein levels significantly alkalinized lysosomal pH and decreased lysosomal enzyme

33 P2X7R stimulation did not kill RPE cells but alkalinized lysosomes by 0.3 U.

34 ulation of the P2X7 receptor (P2X7R) for ATP alkalinizes lysosomes in cultured human retinal pigmente

35 trocytic intracellular pH (pHi) slightly but alkalinized neuronal pHi.

36 R with forskolin/3-isobutyl-1-methylxanthine alkalinized NL ASL but acidified CF ASL; and (iii).

37 ungal pathogens use functional homologues of alkalinizing peptides found in their host plants to incr

38 Ex vivo, single action potentials evoked alkalinizing pH transients of only ~0.01 log unit, but t

39 um chloride (NH4Cl) were used to acidify and alkalinize pHi, respectively.

40 control (pHi 7.3), acidifying pHi to 6.3 or alkalinizing pHi to 8.3 and 8.8 caused small reductions

41 aw blue maize was nixtamalized (hydrothermal alkalinized process), then was wet-milled in a stone mil

42 NHE1 was upregulated by alkalinizing SC pH, whereas this antiporter was downregu

43 ynthesized and tested for their abilities to alkalinize suspension culture medium, with synthetic SnH

44 f OTOP1, that correlated with its ability to alkalinize the cell cytosol.

45 l cells were exposed to ammonium chloride to alkalinize the cytosol.

46 While CFTR modulation has been shown to alkalinize the pH of the alimentary tract and potentiall

47 reased release of malate or citrate, but did alkalinize the rhizosphere to a greater extent than wild

48 Application of the weak base NH4Cl alkalinized the cytosol and caused a dose-dependent incr

49 Trimethylamine (TMA) also alkalinized the cytosol and increased [Ca2+]i.

50 NHE6 alkalinized the endosomal lumen, similar to monensin, an

51 BAG and BAG-F alkalinized the incubation media.

52 However, thiazides induced antidiuresis and alkalinized the urine in lithium-NDI mice lacking the so

53 lumen, V-ATPase inhibition by concanamycin A alkalinized the vacuole and increased BCECF fluorescence

54 Disrupting the LAMP-TMEM175 interaction alkalinizes the lysosomal pH and compromises the lysosom

55 GABA receptor (GABAR)-mediated HCO3- efflux, alkalinizing the cleft and disinhibiting cone CaV channe

56 ipette solution eliminated feedback, whereas alkalinizing the cone cytosol did not, suggesting that H

57 We suggest that alkalinizing the cytoplasm in unstimulated lacrimal acin

58 Alkalinizing the cytosol appeared to partially inhibit C

59 Here, by blocking the vacuolar ATPase, alkalinizing the extracellular pH, or exposing hippocamp

60 bean (Glycine max) leaves that is capable of alkalinizing the media of soybean suspension cells, a re

61 ggest that future therapy be directed toward alkalinizing the pH of CF airways.

62 reased antifungal activity was a function of alkalinizing the phagolysosome.

63 al, suggesting that effects were mediated by alkalinizing the phagolysosome.

64 oxygenic phototrophs, cyanobacteria tend to alkalinize their surroundings, which will encourage carb

65 es chloride from cells, like KCC-2, but also alkalinizes them.

66 Noninduced and induced cells were alkalinized to an equivalent pHi ( approximately 7.7) by

67 on isotonic exchange of Cl- and then rapidly alkalinize upon restoring normal [Cl-].

68 erial homologues that works optimally in the alkalinized urinary tract, a characteristic of urease-me

69 l endocytosis and vacuolar morphology and an alkalinized vacuolar lumen (pHvph1Delta/Delta = 6.8 vers

70 is, pHi of blood neutrophils was analogously alkalinized, which could be normalized by C5aR1 inhibiti

71 productive tract, the spermatozoan cytoplasm alkalinizes, which in turn activates a Ca2+-selective cu

72 e extracted from 5mL wine sample (previously alkalinized with 0.5% sodium hydroxide) using 5mL aceton