コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 a class of molecules termed 'isocarbostyril alkaloid'.
2 sin I, the most recently isolated communesin alkaloid.
3 e spectra differ from those of the authentic alkaloid.
4 s for the total synthesis of pyrroloindoline alkaloids.
5 or the occurrence of the described imidazole alkaloids.
6 d in the short total synthesis of four venom alkaloids.
7 erpenoid atropurpuran, and other diterpenoid alkaloids.
8 fully decorated aminocyclitol cores of these alkaloids.
9 r ingestion of toxins, such as pyrrolizidine alkaloids.
10 tions allow efficient access to the targeted alkaloids.
11 emine and gelsedine classes of the gelsemium alkaloids.
12 10-fold increase in potency over the natural alkaloids.
13 amides, which are cytotoxic pyrroloquinoline alkaloids.
14 a fascinating class of monoterpenoid indole alkaloids.
15 rinting applied to simple as well as complex alkaloids.
16 ontaneous cyclization affords cinchonamidine alkaloids.
17 s may also be present, such as pyrrolizidine alkaloids.
18 of several novel flavonoids and cyclopeptide alkaloids.
19 heptane-containing member of the hapalindole alkaloids.
20 ion to deliver the heptacyclic core of these alkaloids.
21 lanaceae and other plants containing tropane alkaloids.
22 substituted pyrrolidines, including oxindole alkaloids.
23 ic nitrogenous structures resembling natural alkaloids.
24 hrough the production of biologically active alkaloids.
25 ng that robbers were less tolerant of nectar alkaloids.
26 ine framework commonly found in a variety of alkaloids.
27 hway leading to a large family of polycyclic alkaloids.
28 ctive syntheses of strychnos and chelidonium alkaloids.
29 ethylxanthines, but also biogenic amines and alkaloids.
30 g was also applied to the synthesis of sedum alkaloids.
34 pound zoanone A (1), together with eight new alkaloids, 3beta,14alpha-dihydroxy-28-deoxyzoanthenamine
35 l syntheses of the anticancer isocarbostyril alkaloids (+)-7-deoxypancratistatin, (+)-pancratistatin,
37 vities of all naturally occurring communesin alkaloids A-I and eight complex derivatives against five
39 rgeting the hexacyclic calyciphylline B-type alkaloids, a subfamily of the Daphniphyllum natural prod
40 ytotoxicity, we further profiled this unique alkaloid across panels of discrete molecular targets.
41 nt metals, metal complexes, amphiphiles, and alkaloids allow tailoring properties for known applicati
42 escens root, we found that the quinolizidine alkaloid aloperine is a KCNQ-dependent vasorelaxant that
43 Total syntheses of the monoterpenoid indole alkaloids (+/-)-alstoscholarisine B and C were accomplis
45 emical diversity and biological relevance of alkaloids, amines, steroids, and peptides, most aspects
46 e is converted into akuammicine, a Strychnos alkaloid, an elusive biosynthetic transformation that ha
49 by the concise synthesis of isocryptolepine alkaloid and a series of its synthetic analogues with de
50 imetic total synthesis to access the natural alkaloid and biosynthetic intermediates in racemic form
51 ving amino acids, different phenylpropanoid, alkaloid and terpenoid classes, and ferrochelatase activ
52 igin of Dysoxylum alkaloids, since 6 natural alkaloids and 12 synthetic analogues were obtained with
53 the oroidin family of marine sponge-derived alkaloids and are, for the most part, dimeric in nature.
55 pounds like phenylpropanoids and flavonoids; alkaloids and glycosides of flavour-related volatile com
56 this work was focused in the search of these alkaloids and of polyphenols in one monofloral and two m
57 o unreveal potential role of steroidal glyco-alkaloids and phenylpropanoids during early blight resis
58 lic route to tropolone-containing colchicine alkaloids and provides insights into the unique chemistr
60 egy that can produce a wide range of complex alkaloids and related structures for future biomedical i
61 ion of eight major aglycones of polyphenols, alkaloids and sapogenins in 20 differently sourced night
63 e safe for feed consumption, since the ergot alkaloids and the regulated mycotoxins were below their
64 e-activity relationships (SAR) of colchicine alkaloids and their analogues with modified A, B, and C
66 The biosynthesis of the N. fumigata ergot alkaloids and their relation to those produced by altern
68 ent of the absolute (S)-configuration of the alkaloid, and together, these data engender the structur
69 derivatives, 26.6% are terpenoids, 5.7% are alkaloids, and 17% are classified as other metabolites.
70 g phenolic acids, organic acids, flavonoids, alkaloids, and betanin, more than 80 showed greater than
71 eraniol, the precursor of monoterpene indole alkaloids, and cannabigerolic acid, the cannabinoid prec
73 tically important amino acids, cannabinoids, alkaloids, and fatty acids, the high altitude temperate
75 embers of polyene macrocycles, pyrroloindole alkaloids, angucyclines, and leupeptins chemical familie
76 amine H, isodaphlongamine H, and a bioactive alkaloid, annotinolide A, which shows antiaggregation ac
79 ry metabolites that comprise the diterpenoid alkaloids are categorized into C18, C19, and C20 familie
80 highly bridged frameworks of the diterpenoid alkaloids are discussed in the context of eight recent s
81 ticular, sulfonamide derivatives of cinchona alkaloids are highly enantioselective desymmetrization c
83 The fungal-derived bicyclo[2.2.2]diazaoctane alkaloids are of interest to the scientific community fo
86 volved in the biogenesis of hapalindole-type alkaloids as a new family of calcium-dependent enzymes,
88 am-containing drugs, and naturally occurring alkaloids, as well as for the selective cyanation of the
89 insights on the synthesis of these strained alkaloids, as well as mild conditions for the exhaustive
91 /oxa-Michael addition cascade using cinchona alkaloid-based chiral bifunctional amino-squaramide cata
92 frogs sequester lethal amounts of steroidal alkaloid batrachotoxin (BTX) in their skin as a defense
93 of plant natural products, including indole alkaloids, benzylisoquinoline alkaloids, hydroxycinnamic
95 of infected oranges showed diffusion of the alkaloids between the orange layers after 4 days post in
96 a few compounds from the benzylisoquinoline alkaloid (BIA) family of THIQs, low product titers imped
98 has been long postulated, benzylisoquinoline alkaloid (BIA) transporters from opium poppy (Papaver so
106 tion of complex natural products such as the alkaloids brucine and strychnine, leading to interesting
107 m produces more than 40 structurally related alkaloids, but most studies have focused on just two of
108 nt enantioselective strategy to access these alkaloids by use of a challenging palladium-catalyzed as
110 ped and validated to measure tobacco-related alkaloids, carcinogens, and their metabolites in raw was
111 of four to now six different natural product alkaloid classes by distinguishing late stage key strate
112 xicity toward zebrafish embryos of Dysoxylum alkaloids, comparing their toxicity with that of their c
113 ns, for example, outstanding higher level of alkaloid compounds (e.g., imidazoles) in rice straw burn
114 MYMD-1 is a synthetic derivative of tobacco alkaloids, compounds that possess immunoregulatory prope
115 ntact with infected oranges for 48 h, showed alkaloid concentrations >=10 ug kg(-1) on epicarp layer.
117 ne (1), a member of the securinega family of alkaloids containing an unusual oxazabicyclo[3.3.1]nonan
120 f reward chemistry - nectar sugar and pollen alkaloid content - impacted competition for bumblebee vi
121 its, namely, vernalization requirement, seed alkaloid content, and resistance to anthracnose and Phom
129 hesis of the complex hexacylic Daphniphyllum alkaloid (-)-daphlongamine H has been accomplished.
130 udies indicate that concentration of tropane alkaloids decreases, and it depends on the compound, obs
131 orms can facilitate the discovery of tropane alkaloid derivatives as new therapeutic agents for neuro
133 of cryptolepine, a pharmacologically active alkaloid derived from the roots of Cryptolepis sanguinol
134 med at the identification of novel imidazole alkaloids derived from histamine or histidinol and gener
135 g effect between the chirality of a cinchona alkaloid-derived aminophosphine ligand for the silver(I)
142 We herein tested the activity of solenopsin alkaloids extracted from two species of fire ants agains
144 rocyclization reaction, generates the marine alkaloids (-)-fasicularin 2 and a pro-forma synthesis of
145 dine and other arcutinidine-type diterpenoid alkaloids feature an intricate polycyclic, bridged frame
146 ctive syntheses of hexacyclic aspidoalbidine alkaloids (+)-fendleridine (2) and (+)-acetylaspidoalbid
151 ging, we identified that neferine, a natural alkaloid from Nelumbo nucifera, induces autophagy by act
154 esis of (22 R)- and (22 S)-27-norspirosolane alkaloids from tigogenin, epismilagenin, and smilagenin
156 cluster co-localizes with a tomato steroidal alkaloid gene cluster and is syntenic to a chromosome 12
157 ties are used for both, pharmaceutical opium alkaloid generation and poppy seed production for food u
158 s from 4 were also shown to categorize their alkaloid guests according to their structural similarity
159 compounds were synthetized from the natural alkaloid haemanthamine and tested in vitro for their eff
162 A five-step total synthesis of Dysoxylum alkaloids has been achieved using a biomimetic approach
163 dine, a caged pentacyclic monoterpene indole alkaloid, has been accomplished in both racemic and enan
165 ugars, proteins, capsaicinoids, fatty acids, alkaloids have been shown to have alpha-amylase and alph
168 cluding indole alkaloids, benzylisoquinoline alkaloids, hydroxycinnamic acid amides, phenylacetaldehy
169 eered baker's yeast to produce the medicinal alkaloids hyoscyamine and scopolamine, starting from sim
177 aracterised, but the potential role of these alkaloids in animal pathogenesis has not been studied ex
178 Echinopsis pachanoi) cross section, tropane alkaloids in jimsonweed ( Datura stramonium) fruits and
179 In this study, the degradation of tropane alkaloids in pasta under boiling (100 degrees C during 1
180 So far, risk assessments regarding opium alkaloids in poppy seeds were mainly based on the morphi
182 s of several BIAs, including six non-natural alkaloids, in cascades from l-tyrosine and analogues.
184 t years, poppy seed contamination with opium alkaloids, including thebaine, gave repeatedly reasons f
189 ]oxy-6-(hydroxymethyl)oxane-3,4,5-triol], an alkaloid isolated from the root of Panax ginseng, slows
191 The okaramines are a class of complex indole alkaloids isolated from Penicillium and Aspergillus spec
193 core in the eastern portion of the Veratrum alkaloids jervine (1), cyclopamine (2), and veratramine
194 formal racemic syntheses of tricyclic marine alkaloids, lepadiformines A, B, and C as well as their C
196 ey challenge in the synthesis of diterpenoid alkaloids lies in identifying strategies that rapidly co
197 id bufalin (from Chinese toad venom) and the alkaloid lycorine (from Amaryllidaceae species) to be ef
198 The observed polypharmacology of kratom alkaloids may support its utilization to treat opioid us
201 quinazoline structures including the natural alkaloids, methylisatoid and cephalanthrin B, in high yi
202 pharmaceutically valuable monoterpene indole alkaloids (MIAs) in Catharanthus roseus are derived from
204 alyl linker offering rapid access to complex alkaloid mimics in very few experimentally simple steps:
205 a potential precursor for synthesizing a few alkaloid molecules such as ergot, hapalindole alkaloids,
206 method to determine the content of six opium alkaloids (morphine, codeine, thebaine, noscapine, papav
207 f the sponge-derived dibrominated bis-indole alkaloids, namely, echinosulfone A (2) and the echinosul
209 een used in the synthesis of other strychnos alkaloids, no investigations have been performed into th
211 plexity and exhibiting pharmaceutical (poppy alkaloids), nutritional (rosemary extracts) or cosmetics
213 iosynthesis of indole and benzylisoquinoline alkaloids of plant origin, some of which have pharmacolo
215 vity relationship-guided substitution of ETP alkaloids offers versatile derivatization while maintain
222 ly engineered a shortened benzylisoquinoline alkaloid pathway to produce (S)-norcoclaurine in yeast.
225 ing efforts to reconstruct plant isoprenoid, alkaloid, phenylpropanoid, and polyketide biosynthetic p
226 esis of arborisidine, a unique Kopsia indole alkaloid possessing a fully substituted cyclohexanone ri
227 first in a new class of pyrroloiminoquinone alkaloids possessing a highly strained multibridged ring
230 aliphatic aldehydes to give enantioenriched alkaloid products with up to 99% ee STRs are thus valuab
231 c catalysis conditions with dimeric cinchona alkaloids, providing excellent enantiocontrol of the pro
235 Fungal bicyclo[2.2.2]diazaoctane indole alkaloids represent an important family of natural produ
237 sis of hybrubin A, a bipyrrole tetramic acid alkaloid representing a new carbon framework derived fro
238 subunits present in Aspidosperma and Kopsia alkaloids, respectively, en route to highly efficient sy
240 pful to annotate specific compounds, such as alkaloids, saponins, flavonoids, and terpenoids, which a
242 rk provides a blueprint for building diverse alkaloid scaffolds and enables the targeted overproducti
244 rometry (LC-MS) results found hallucinogenic alkaloids scopolamine and atropine in the quids, while s
245 tive on the biosynthetic origin of Dysoxylum alkaloids, since 6 natural alkaloids and 12 synthetic an
246 The sensor displays good selectivity toward alkaloid species and, in particular, the hallucinogenic
248 s used in the total synthesis of the Stemona alkaloid (-)-stemaphylline in just 11 steps (longest lin
251 inding and functional profiles of the kratom alkaloids, suggesting potential utility for managing pai
252 ere a good match for closely related oroidin alkaloids, supporting the structure of the synthetic mat
254 mmetric syntheses of all eight tetraponerine alkaloids (T1-T8) were achieved using the diastereoselec
257 Despite disparate biosynthetic machinery, alkaloid, terpene, and polyketide-producing organisms ha
260 nicotine, a highly addictive, plant-derived alkaloid that binds to nicotinic acetylcholine receptors
263 nd liriodenine are plant-derived aporphinoid alkaloids that exhibit potent inhibitory activity agains
265 reviously undescribed sarpagine-like N-oxide alkaloids that have been targeted and isolated from the
266 covery of a new class of pyrroloiminoquinone alkaloids that possess selective bioactivity against pan
269 d on the morphine level, whereas other opium alkaloids thereunder thebaine could not be finally evalu
270 ecies known for its content in pyrrolizidine alkaloids, this work was focused in the search of these
271 s, through dearomatizing ortho-substitution; alkaloids, through Hofmann-type elimination; tropolone a
272 polone and furan, through cycloaddition; and alkaloids, through three-component fragmentation-couplin
273 s roseus produces bioactive terpenoid indole alkaloids (TIAs), including the chemotherapeutics, vincr
275 expand the potential application of B. caapi alkaloids to other brain disorders that may benefit from
276 terpenoids to the periderm and sesquiterpene alkaloids to the cortex layer of Tripterygium roots.
277 total synthesis, we found that the peptidic alkaloid tryptorubin A can be one of two noncanonical at
280 een described for the synthesis of versatile alkaloid-type azetidines from simple building blocks wit
281 ative methods for the synthesis of versatile alkaloid-type compounds from oxiranylmethyl tetrahydrois
282 f representative members of the schizozygine alkaloids, (+)-vallesamidine and (+)-14,15-dehydrostremp
283 henols were determined, but no pyrrolizidine alkaloid was detected in the analysed honey samples.
284 erized to a planar enamine intermediate, the alkaloid was eventually obtained as a 1:1 mixture of C6
286 our quest to discover new monoterpene indole alkaloids, we demonstrate the utility of the MetWork pla
289 ted analysis was performed and other tropane alkaloids were found, as scopine, tigloidine or convolvi
291 possible scaffolds for bis(cyclotryptamine) alkaloids were originally postulated in the 1950s, but o
293 substituted and spiro-tetrahydroisoquinoline alkaloids were readily prepared in one-step and high yie
295 compounds, two 14-ring-membered cyclopeptide alkaloids, which were named opuntisines A and B, were el
297 l synthesis of (+)-granatumine A, a limonoid alkaloid with PTP1B inhibitory activity, in ten steps.
298 (-)-Himeradine A is a complex lycopodium alkaloid with seven rings and ten stereogenic centers th
299 e and efficient synthetic route toward these alkaloids would allow for improvements in their solubili