ライフサイエンスコーパス: alkoxy

1 the resulting 4-hydroperoxy-2-alkanols to 3-alkoxy-1,2-dioxolanes, and Lewis acid mediated homologat

2 n at C-7, then good to excellent yields of 7-alkoxy-10-methoxy-3H-naphtho[2.1-b]pyrans are afforded.

3 ate dehydrogenase (DHODH) inhibition by 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine derivatives as well as

4 ectious diseases, an original series of 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidines endowed with notable

5 e steric hindrance as is the case with the N-alkoxy-2,2,6,6-tetramethylpiperidines.

6 of alkyl halides yields the corresponding 3-alkoxy-2-halocyclohex-2-enones via a 1,4 alkyl group mig

7 esis of peptides capped with an N-terminal 2-alkoxy-2-oxazoline or 2-oxazolidinone unit.

8 For the ethynylphenyl alkoxy 21,23-dithiaporphyin, birefringent, soft-crystall

9 d range of substituted, functionalized alpha-alkoxy 2H-naphthalenones from readily available N-tosylh

10 eterocyclization of o-nitrobenzylamines to 3-alkoxy-2H-indazoles is reported.

11 porating a head-to-head linkage containing 3-alkoxy-3'-alkyl-2,2'-bithiophene are synthesized.

12 second S(N)Ar reaction on the deactivated 1-alkoxy-3-fluorobenzene intermediates have been investiga

13 24 was synthesized in six steps from a key 2-alkoxy-3-p-phenoxypropionic acid 26 that was made using

14 ated substrates-namely, 7-alkoxycoumarins, 7-alkoxy-4-(trifluoromethyl)coumarins, and 7-alkoxy-4-meth

15 Compound 1 (SKI-606, bosutinib), a 7-alkoxy-4-[(2,4-dichloro-5-methoxyphenyl)amino]-3-quinoli

16 3-Alkoxy-4-cyanothiophene units are used as building block

17 s associated with the alkoxy groups of the 3-alkoxy-4-cyanothiophene, while the central acceptor part

18 yn-1-ols and 5-endo-dig iodocyclization of 1-alkoxy-4-ethoxy-3-yn-1,2-diols, respectively.

19 7-alkoxy-4-(trifluoromethyl)coumarins, and 7-alkoxy-4-methylcoumarins-with a C1-C7 side chain.

20 r impregnated with positively charged poly(3-alkoxy-4-methylthiophene) as luminescent reporters.

21 We previously reported that several 7-alkoxy-4-phenylamino-3-quinolinecarbonitriles were poten

22 multisubstituted thiophenes such as alkyl 4-alkoxy-5-amino-3-methylthiophene-2-carboxylates through

23 l evaluation of members of a new series of 3-alkoxy-5-aminopyridine derivatives that display good sel

24 6-Alkoxy-5-aryl-3-pyridincarboxamides, including the brain

25 We identified 6-alkoxy-5-aryl-3-pyridinecarboxamides as potent CB1 recep

26 aluation of a new class of DPD analogues, C4-alkoxy-5-hydroxy-2,3-pentanediones, termed C4-alkoxy-HPD

27 with pyrrole, results in the formation of 5-alkoxy-5-phenyl dipyrromethane derivatives, which functi

28 ted coumarins containing alkyl, aryl, silyl, alkoxy, acyl, and ester groups have been prepared in mod

29 Potassium 1-(alkoxy/acyloxy)alkyltrifluoroborates have been synthesiz

30 e performed experiments prove that water and alkoxy adducts are formed not only during temperature pr

31 sformations and the formation of hydroxy and alkoxy adducts has not been reported yet.

32 However, the formation of hydroxy and alkoxy adducts of stevioside and of its hydrolysis produ

33 ely, if stereochemical control from the beta-alkoxy aldehyde is desired, a Lewis acid-catalyzed enols

34 ner while negating any influence of the beta-alkoxy aldehyde substituent.

35 reactions of these enolates with chiral beta-alkoxy aldehydes have also been investigated in conjunct

36 The alkoxy/alkyl/halogen-substituted biaryls produced are us

37 Diels-Alder reactions of a range of 1-(alkoxy/alkyl/halogen-substituted phenyl)buta-1,3-dienes

38 condary allyl methyl ether against the alpha-alkoxy alkyllithium configuration.

39 Cl, followed by the reactions of the alkyl, alkoxy, alkylperoxy and Criegee intermediates active in

40 gents was found to afford biaryls exhibiting alkoxy, alkylthio, amino, ketone, cyano, nitro, ester, a

41 However, in this study it was found that o-alkoxy alpha-arylenamides were reduced with high enantio

42 tive arylcuprate conjugate addition to gamma-alkoxy-alpha,beta-enoates and syn-selective azidation at

43 addition reactions with cis and trans gamma-alkoxy-alpha,beta-enoates.

44 hod for 1,3-reductive transposition of alpha-alkoxy-alpha,beta-unsaturated hydrazones to provide E-al

45 astereoselectivity in the reduction of alpha-alkoxy-, alpha-acyloxy-, and alpha-alkylamino-substitute

46 methene) is equipped with electron-rich beta-alkoxy/alpha-aryl-substituted pyrrole moieties to satura

47 The compounds are a butadiene (U-0126), an N-alkoxy amide (CI-1040), two CI-1040 analogues (an anthra

48 5-Alkoxy, amino, and N,N-dialkylamino-3-aryl/alkyl-4-(2-R-

49 Several alkoxy-amino-lambda(6) -sulfanenitriles are prepared wit

50 The isomerization of 5-alkoxy/amino-3-arylisoxazoles, bearing unsaturated carbo

51 s, which were separated from the byproduct 4-alkoxy analogues.

52 The intramolecular addition of both an alkoxy and acyl substituent across an alkene, oxyacylati

53 res", except MS 1, were integrated with both alkoxy and alkylamino donor functionalities that differ

54 ons under nonchelating conditions with alpha-alkoxy and alpha,beta-bisalkoxy aldehydes is described.

55 ping it organic: A direct synthesis of alpha-alkoxy and alpha-amino ester derivatives by direct reduc

56 ivers a range of enantiomerically pure alpha-alkoxy and alpha-amino substituted products.

57 k of a lithiated intermediate onto the alpha-alkoxy and alpha-amino sulfoxides as they form, and (ii)

58 The approach involves the synthesis of alpha-alkoxy and alpha-amino sulfoxides in >/=99:1 dr and >/=9

59 a strong magnesium chelate with the reacting alkoxy and carbonyl groups dictates the observed reactiv

60 are sandwiched between the pyrenes, with the alkoxy and NHAc groups emerging at the sides.

61 s spirosilanes bearing alkyl, aryl, halogen, alkoxy, and trifluoromethyl substituents on the aryl rin

62 reaction in alcohols and thiols to afford 3-alkoxy- and 3-arylthio-substituted 1,2-diphenylcycloprop

63 Electron-rich alkoxy- and chloro-substituted azaspirocyclic cyclohexad

64 gioselective para-C-H cyanation of hydroxy-, alkoxy-, and benzyloxyarene derivatives has been introdu

65 anes is noteworthy, including alkyl-, aryl-, alkoxy-, and halosilanes.

66 usly with alcohols and ethers to form the 12-alkoxy anions 12-CB(11)Me(11)OR.

67 Condensation of 1,2-diamino-4,5-bis(n-alkoxy)arenes with an oligopyridyl-type alpha-diketone a

68 performs meta C-H arylation of a variety of alkoxy aromatics including 2,3-dihydrobenzofuran and chr

69 tones gave synthetically interesting amido-, alkoxy-, aryloxy-, and phosphate-substituted pyrroles in

70 s radius and intramolecular S(thiazolyl)...O(alkoxy) attraction promote HH macromolecular architectur

71 he organolithium-mediated conversion of beta-alkoxy aziridines into substituted allylic sulfonamides,

72 ahydronaphthyridine mGlu5 PAMs containing an alkoxy-based linkage as an acetylene replacement.

73 e formed by radical decarboxylation of alpha-alkoxy beta-phenylthio acids via the corresponding Barto

74 Bis-4,4'-alkoxy bipyridine dendrons were prepared and employed to

75 Investigation of both the mono- and the bis-alkoxy-bridged complexes [(NNO(R))InX](2)[mu-Y][mu-OEt]

76 embered cyclic transition state in which the alkoxy C-O bond is cleaved with no direct participation

77 as been developed and involves the methylene alkoxy carbamate (MAC) self-immolative unit.

78 ound 17 was then converted in three steps to alkoxy carbamate 20.

79 whereas Marine DOM was markedly enriched in alkoxy carbon (e.g., carbohydrate-like moieties).

80 d spectra indicated that a large fraction of alkoxy carbons were not protonated.

81 thesis of several substituted N-(pivaloyloxy)alkoxy-carbonyl prodrugs of 14 designed to circulate ine

82 /Et(3)SiH or (t)BuMgCl affords the desired 2-alkoxy carboxylic acid in moderate to excellent chemical

83 Two complementary approaches to prepare 2-alkoxy carboxylic acids have been developed.

84 ounds illustrate that the columns with short alkoxy chains (six carbons) are more influenced by the p

85 Platinum dimers with longer alkoxy chains are shown to be unique examples of liquid

86 vatives, except for the COF with the longest alkoxy chains examined (OC(12)H(25)), which, although sh

87 to an extended molecular shape, wherein the alkoxy chains of the individual ligand components lie on

88 4-substituted triphenylene with the shortest alkoxy chains was liquid crystalline (Col(r)).

89 anic D21L6 and D25L6 dyes, endowed with long alkoxy chains, show no significant change in the electro

90 aining six, eight, and ten carbons of linear alkoxy chains.

91 solvent- and metal-free methodology for the alkoxy-chalcogenylation of styrenes, using molecular iod

92 minal epoxides bearing alkyl, alkenyl, aryl, alkoxy, chloromethyl, phthalimido, and acetal functional

93 An alkoxy complex [PhBP(Ph)3]Ru-OCHPh2 (4b) was observed (b

94 ulfonate proved optimal, but other alkyl and alkoxy derivatives were also reasonably reactive.

95 tes of esters, including those bearing alpha-alkoxy derivatives, underwent arylation in high yield wi

96 etal-catalyzed cyclization of enynols, alpha-alkoxy dioxolane-tethered 1,3-enynes exclusively undergo

97 conjugation pathways between the substituent alkoxy donating groups and the pyridyl acceptor groups.

98 varied between acyclic and cyclic while the alkoxy donors are varied in terms of their number and po

99 bone in which the position and the number of alkoxy donors were systematically varied.

100 (b) thiazole electron-deficiency compensates alkoxy electron-donating characteristics, thereby loweri

101 The intermediate zinc beta-alkoxy enamines can be subjected to a tandem cyclopropan

102 ed (Me)4NBH(OAc)3 reduction of E- and Z-beta-alkoxy-enones 30 was found cleanly to achieve the requir

103 vering more than 25 siloxanes with siloxy or alkoxy functional groups at both termini, and can also b

104 building blocks with enlarged pai-systems or alkoxy functionalities showed significant stability towa

105 The alkoxy-functionalized silicon surfaces were used as reac

106 ulfonium tetrafluoroborate (DMSTF) with beta-alkoxy-gamma-dithiane lactams.

107 access to acyl/aryl, acyl/alkenyl, and acyl/alkoxy gold carbenes by in situ expulsion of sulfur diox

108 ch depend on the relative orientation of the alkoxy group and the establishment of adequate pai-pai i

109 yl group at the 5-position and a substituted alkoxy group at the 6-position of the pyrrolo[2,1-f][1,2

110 rolled for the inductive destabilization, an alkoxy group can accelerate acetal hydrolysis by up to 2

111 -alkoxy-substituted acetals indicate that an alkoxy group can accelerate acetal hydrolysis by up to 2

112 itions suggest that the presence of an axial alkoxy group distorts the oxocarbenium ion, changing its

113 ch as 1, 2, and 3 degrees ) as the source of alkoxy group during this transformation.

114 ceed through a sequence of alkyne hydration, alkoxy group elimination, and intramolecular conjugate a

115 ional data of carboindation suggest that the alkoxy group enhances the interaction between InI(3) and

116 t transfer of one of the ring protons to the alkoxy group for the concomitant alcohol elimination.

117 termediate oxocarbenium ions display the C-3 alkoxy group in a pseudoaxial orientation to maximize el

118 g significant RNAi efficacy by orienting the alkoxy group in the major groove.

119 binding during delivery via placement of the alkoxy group in the minor groove, while maintaining sign

120 re designed to explore the importance of the alkoxy group in the N-acyl aminal and functional groups

121 vity (>99%) can be achieved keeping an ortho alkoxy group in unsymmetrical 1,2-dialkynylbenzene in th

122 Overall, the alkoxy group is -41 +/- 7 kJ/mol more stable than physis

123 The acceleration of acetal hydrolysis by an alkoxy group is better explained by electrostatic stabil

124 ion structures (TS A and D), where the alpha-alkoxy group is gauche to the thioether moiety.

125 appreciably by increasing the size of the R9 alkoxy group or by alpha-methyl branching adjacent to th

126 pies show the boron is chelated by the alpha-alkoxy group rather than the more distal oxazolidinone c

127 equally large activation barrier to form an alkoxy group via a carbenium-ion transition state.

128 alkynyl ethers to elucidate the effect of an alkoxy group was conducted in parallel with calculations

129 tal hydrolysis between a substrate where the alkoxy group was tethered to the acetal group by a five-

130 None of the OP-albumin adducts lost an alkoxy group, leading to the conclusion that aging did n

131 ivity is controlled by the electron-donating alkoxy group, whereas diastereo- and enantioselectivity

132 alkanol molecule after a protonation on the alkoxy group.

133 to 20-fold compared to substrates without an alkoxy group.

134 ly comparable substrates that do not have an alkoxy group.

135 CBM, because of the electron donation of the alkoxy group.

136 utyl, phenyl, and 3,3,3-trifluoropropyl) and alkoxy groups (monoethoxydimethyl-, diethoxymethyl-, and

137 es, where the two metal ions with associated alkoxy groups [Zn((II))1:((-)OCH3) and Zn((II))1:((-)O-p

138 gainst the Charton steric parameter, nu, for alkoxy groups are linear.

139 Importantly, we used novel CF(3)-alkoxy groups as bioisosteric replacements of a fluorina

140 ther hand, studies of pentopyranoses bearing alkoxy groups at C-2, C-3, and C-4 showed that the alkox

141 The reactions of acetals with alkoxy groups constrained to either equatorial or axial

142 groups at C-2, C-3, and C-4 showed that the alkoxy groups exerted powerful influences on selectivity

143 The direct displacement of alkoxy groups from the beta position of aromatic and uns

144 t steric effect was noted, but the number of alkoxy groups had almost no influence.

145 From this analysis, alkoxy groups have been shown to strongly affect the ele

146 , thereby placing the sterically demanding 8-alkoxy groups in the major or minor groove, respectively

147 es generated by hydrolysis of some of the Si-alkoxy groups in the trialkoxy moieties used to bind man

148 The mechanism of direct displacement of alkoxy groups in vinylogous and aromatic esters by Grign

149 ables the late-stage introduction of complex alkoxy groups into bioactive molecules, providing a prac

150 ears to control the dimer geometry, with the alkoxy groups of one molecule sliding into registry with

151 ienothiophene end groups associated with the alkoxy groups of the 3-alkoxy-4-cyanothiophene, while th

152 at different positions of the benzene core (alkoxy groups of varying chain length with diverse funct

153 rial positions in the oxocarbenium ions, but alkoxy groups prefer axial conformers.

154 ereas with NCS addition of both chlorine and alkoxy groups takes place across the chromene double bon

155 step procedure to initially covalently graft alkoxy groups to boron atoms and the subsequent hydrolyt

156 polyarene upon the nucleophilic addition of alkoxy groups to the exterior carbon atom of the corannu

157 The unusual selectivities controlled by the alkoxy groups were demonstrated for a range of other het

158 al diols via exchange of one of the boronate alkoxy groups with activation of the acyl imine via hydr

159 ubstitutions of R6 and R7 hydroxyl groups by alkoxy groups, acetoxy groups, or benzyloxy groups could

160 The cyclotrinaphthylenes carry six alkoxy groups, and derivatives featuring OHex, OBu, OiPr

161 The biosynthesis of branched alkoxy groups, such as the unique t-butyl group found in

162 ecreased slightly with increasing numbers of alkoxy groups.

163 lkoxy-5-hydroxy-2,3-pentanediones, termed C4-alkoxy-HPDs.

164 urnishing an eta5,eta5-bis(indenyl)zirconium alkoxy hydride complex and free olefin.

165 e, reductive cleavage of the resulting alpha-alkoxy hydroperoxide, trapping of the generated alkyl ra

166 zed 2-benzylfurans are described for azido-, alkoxy-, hydroxyl-, amide-, and tetrazolyl adducts.

167 ne-3-carbaldehydes leads to the synthesis of alkoxy/imidazole-substituted 1,3-dihydrofuro[3,4-b]quino

168 The initially formed 2,3-dihydro-2-alkoxy-indeno[1,2-b]pyrano-4,5-diones are labile compoun

169 high syn selectivity was obtained with alpha-alkoxy ketones and other compounds via Felkin-Ahn contro

170 ive allylic substitutions with acyclic alpha-alkoxy ketones catalyzed by a metallacyclic iridium comp

171 thers, prepared from the corresponding alpha-alkoxy ketones in a two-step sequence involving enol tri

172 nolates generated in situ from acyclic alpha-alkoxy ketones.

173 catalyst and the C-5'-oxyanion of the basic alkoxy leaving group.

174 uity for reactions involving relatively poor alkoxy leaving groups.

175 Using analogous poly(alkoxy) ligands allows the preparation of bis(2-phenylpy

176 cumented to be general for a variety of beta-alkoxy methyl ketone analogues and aldehyde partners.

177 ted aldol reactions of certain types of beta-alkoxy methyl ketone show remarkably high levels of ster

178 rticle presents studies that illustrate beta-alkoxy methyl ketone-derived boron enolates undergo dias

179 es dominant 1,5-anti induction from the beta-alkoxy methyl ketone-derived enolate partner while negat

180 ctions of boron enolates generated from beta-alkoxy methylketones with aldehydes.

181 5-syn stereoselectivities of beta-alkyl-beta-alkoxy methylketones.

182 sequent reaction with the alcohol to give an alkoxy-Mn(V) species, and (3) carbonyl-forming eliminati

183 mprovement and generalization of the "inside-alkoxy" model used to rationalize stereoselectivities of

184 95L/Y337A phosphonylated with the most bulky alkoxy moiety, S(P)-cycloheptyl methylphosphonate.

185 ine benzyl esters from alpha-alkyl and alpha-alkoxy N-protected aminoaldehydes with benzyl diazoaceta

186 Alkoxy-N-methyl-acetiminium salts were prepared by addit

187 C, these iminoesters gave the corresponding alkoxy-N-methyl-acetiminium salts with (E)-configuration

188 Furthermore, in the presence of di-hydroxy/alkoxy naphthalene donors, efficient charge-transfer com

189 HOO(-)(H2O) to that of microsolvated normal alkoxy nucleophiles, RO(-)(H2O), in reaction with CH3Cl

190 p from our first series was replaced with an alkoxy or 1-ethenyl group were designed, synthesized, an

191 l)-4,5alpha-epoxypyridomorphinans possessing alkoxy or acyloxy groups at C-14 was synthesized and eva

192 via substitution of all 12 B-H vertices with alkoxy or benzyloxy (OR) substituents engenders reversib

193 ran derivatives were synthesized from simple alkoxy or halonicotine intermediates.

194 The BODIPY dyes bearing alkoxy or nonfunctionalized phenoxy moieties are charact

195 Five analogous compounds with phenol, alkoxy, or alkoxycarbonyl substituents were synthesized

196 rrangements (Wittig rearrangements) of alpha-alkoxy oxazolidinone enolates are described.

197 zing formyl hydrogen bond exists between the alkoxy oxygen and the aldehyde proton.

198 mational alignment of lone pair of the ortho alkoxy oxygen or the nitrogen in pyridine systems).

199 as the ligand, the reaction proceeds via an alkoxy palladium intermediate that increases the proton

200 A series of functionalized 6-alkoxy phenalenones was prepared through an unprecedente

201 is(alkoxy)phenyl 4-aminobenzoates/3,4,5-tris(alkoxy) phenyl 4-aminobenzoates with 1,3,5-triformylphlo

202 the facile threefold condensation of 3,4-bis(alkoxy)phenyl 4-aminobenzoates/3,4,5-tris(alkoxy) phenyl

203 poly(ethylene oxide) (PEO), and the soluble alkoxy-PPV derivative poly[2-methoxy-5-(3',7'-dimethyl-o

204 gle, macrocyclic esterase-cleavable (acyloxy)alkoxy prodrug.

205 t in vivo ADME study of macrocyclic (acyloxy)alkoxy prodrugs, and it remains to be established if the

206 ones-directed by the alkoxide of the 1-azo-3-alkoxy propenes formed in situ via base-induced ring ope

207 We have investigated the effects of the alkoxy protecting group (OMe, OPMB, PMP acetal, tetrahyd

208 relatively insensitive to the nature of the alkoxy protecting group.

209 lene diimide oligomers with an electron rich alkoxy pyrene subunit.

210 A series of 2-aryloxy-4-alkoxy-pyridines ( 1) was identified as novel, selective

211 ribe the synthesis and characterization of 3-alkoxy-pyrrolo[1,2-b]pyrazolines as novel selective andr

212 d for the synthesis of densely substituted 4-alkoxy quinolines via an oxonium ion triggered alkyne ca

213 HO(x), producing the corresponding bicyclic alkoxy radical (BCP-oxy).

214 nce of air were consistent with formation of alkoxy radical (RO(*)).

215 wn to accurately forecast the feasibility of alkoxy radical generation with a given oxidant/base pair

216 n of an allylic alcohol substrate affords an alkoxy radical intermediate that undergoes subsequent C-

217 Mechanistic studies demonstrate that key alkoxy radical intermediates in this reaction are genera

218 equent reactions of alkyl, alkyl peroxy, and alkoxy radical intermediates, and the composition of the

219 of monoperoxyacetals provide no evidence for alkoxy radical intermediates.

220 ubsequent C-C beta-scission of the resulting alkoxy radical intermediates.

221 p substituent, the vibrational energy of the alkoxy radical is increased, but this energy is not stat

222 of a 5-hydroperoxy group to an intermediate alkoxy radical that could be subsequently oxidized to th

223 nyl group; 3) beta-scission of the so-formed alkoxy radical to provide the 4-boryl-2(5H)-furanone and

224 -coupling proceeds with the generation of an alkoxy radical utilizing bond-dissociation free energy (

225 roducts and features a beta scission of a 14-alkoxy radical with concomitant generation of the C8-C13

226 -Z-hexenal in the gas phase, resulting in an alkoxy radical, followed by a rearrangement and subseque

227 y to proceed through the beta-scission of an alkoxy radical, followed by oxidation and C-N cleavage o

228 ydrocatechol 8, engages in an intramolecular alkoxy radical-mediated remote functionalization reactio

229 Radical relay cyclizations initiated by alkoxy radicals are a powerful tool for the rapid constr

230 Reactive alkoxy radicals are proposed as key intermediates, gener

231 Transition-metal hydrides generate alpha-alkoxy radicals by H* transfer to enol ethers.

232 rst determination of the fate of the hydroxy alkoxy radicals formed in the title reactions.

233 Alkoxy radicals have long been known to enable remote C-

234 l groups, the chemistry of BCP-oxy and other alkoxy radicals in the system is diverse.

235 Direct evidence for the formation of alkoxy radicals is reported in radical cascades using tr

236 tic isotope effects in the alpha-cleavage of alkoxy radicals is used here to judge the applicability

237 uggest that acid-catalyzed reactions of beta-alkoxy radicals might be employed in synthetic conversio

238 imide (Me-phth) from beta-Me scission of the alkoxy radicals to form a methyl radical.

239 nch-stable precursor that decomposes to free alkoxy radicals via a previously unreported single-elect

240 om the radical chain reactions propagated by alkoxy radicals, which are formed efficiently inside the

241 be competitive with classic decomposition of alkoxy radicals.

242 esponding nitriles and products derived from alkoxy radicals.

243 ctronic effects assists the fragmentation to alkoxy radicals.

244 a-scission is preferred for the formation of alkoxy radicals.

245 the PR by incorporating gem-difluorines and alkoxy, respectively, at the C4 position of the bis-THF

246 )PPn) wires, capped with isoalkyl ((iA)PPn), alkoxy ((RO)PPn), and dialkylamino ((R2N)PPn) groups, sh

247 with an all-phenylene backbone and different alkoxy side chain substitution patterns were synthesized

248 phenyl ring was substituted with a branched alkoxy side chain, which contributes to higher solubilit

249 These studies were focused on the 2-position alkoxy side chain.

250 Compared to the alkyl substituents, the alkoxy side chains on the thiophene units can effectivel

251 The substitution of alkoxy side chains to the less electron-donating alkyl c

252 ompounds with six and ten carbons of achiral alkoxy side chains were further subjected to studies at

253 ated and compared to composites made with an alkoxy silane sol-gel process.

254 tions to aldehydes containing a single alpha-alkoxy stereocenter generally provide the product diaste

255 idine) ruthenium(II) terminals connected via alkoxy-strapped 4,4'-diethynylated biphenylene units to

256 t blue-shifted pi --> pi* transition for the alkoxy substituent and most red-shifted for the NO(2) gr

257 Interestingly, a single alkoxy substituent at carbon three is sufficient for the

258 Introducing an alkoxy substituent at the 6-position onto the phenalenon

259 lection of reaction conditions, the proximal alkoxy substituent on either the aldehyde (1,3-induction

260 bstituents are preferable, in particular, an alkoxy substituent positioned para to the iodide.

261 onal and experimental data suggest that an N-alkoxy substituent stabilizes the aza-oxyallyl cationic

262 particular, simultaneous introduction of 2'-alkoxy substituents and changing an amide to a keto link

263 ll of the amide linkages are trans and the o-alkoxy substituents are intramolecularly hydrogen bonded

264 ally congested o-terphenyl crown ethers with alkoxy substituents at the 2,3,4-position or 3,4,5-posit

265 ty, while aldehydes with the alpha- and beta-alkoxy substituents in a syn relationship unexpectedly g

266 Aldehydes with the alpha- and beta-alkoxy substituents in an anti relationship in most case

267 arylsulfonamides, suggesting a key role for alkoxy substituents in CA inhibition.

268 f the quinolyl N by introducing alkylthio or alkoxy substituents into the 4 position and vary side ch

269 urprising electron-withdrawing nature of the alkoxy substituents is attributed to a rather strong mix

270 th 24 examples with various halo, alkyl, and alkoxy substituents on either of the aromatic rings.

271 Variation of the 2-N-benzyl and 3-alkoxy substituents resulted in the identification of 3-

272 at the 2,6-positions of DP by alkylamino or alkoxy substituents was tolerated, although at least one

273 mer with most of the studied catalysts, meta-alkoxy substituted aryl boronic acids resulted in the (S

274 romoted arylmethylation of the appropriate 1-alkoxy-substituted 2-nitroresorcinol.

275 inoline-3-carbonitriles for the synthesis of alkoxy-substituted 3H-pyrrolo[3,4-b]quinolines using alc

276 tions with carbohydrates, experiments with 4-alkoxy-substituted acetals indicate that an alkoxy group

277 The hydrolysis of 4-alkoxy-substituted acetals was accelerated by about 20-f

278 2-thiol (in case of an N-nucleophile) or a 2-alkoxy-substituted benzo[b]thiophene (in case of an O-nu

279 Small libraries of 6- and 7-alkoxy-substituted chromen-4-ones showed that a number o

280 ted chromen-4-ones showed that a number of 7-alkoxy-substituted chromenones displayed improved activi

281 The anion radicals of alkoxy-substituted cyclooctatetraenes in hexamethylphosp

282 sulfoxides as they form, and (ii) the alpha-alkoxy-substituted Grignard reagent is configurationally

283 To our knowledge, this is the first alkoxy-substituted platinacyclobutane that has been obse

284 to substrates containing an additional beta-alkoxy-substituted stereocenter exhibits a striking depe

285 confirmed the pseudoaxial preference of C-3 alkoxy-substituted systems and revealed the conformation

286 )-2-nitroresorcinols to the corresponding o-(alkoxy-substituted) arylmethylnitrophenols.

287 zene facilitates the ortho rearrangement of (alkoxy-substituted) benzyl ethers of 1-(O-methyl)-2-nitr

288 ection, while those that bear alpha- or beta-alkoxy substitution exhibit little to no double diastere

289 ion via unprecedented ligand exchange of the alkoxy-surface groups with alkyl or alkenyl-surface grou

290 of discotics with six and nine peripheral n-alkoxy tails were especially designed and accomplished t

291 side chains are less tilted due to a larger alkoxy (ten carbons) buffer zone.

292 for analogous materials obtained from 2,5-di(alkoxy)terephthaldehyde derivatives, except for the COF

293 Alkoxy-terminated silicon quantum dots (SiQDs) were synt

294 The alkoxy-terminated SiQDs are soluble in organic solvents,

295 on spectroscopy (XPS) spectroscopy confirmed alkoxy-terminated surfaces and their ligand exchange rea

296 industry-relevant and challenging siloxy- or alkoxy-terminated vinylsilanes.

297 ligands covalently linked via acetylenic and alkoxy tethers to rigid inositol orthoformate platforms

298 ctional group tolerance (amino, nitro, halo, alkoxy, thiomethoxy, and S- and N-heterocyclic compounds

299 arkovnikov reactions that involve siloxy- or alkoxy(vinyl)silanes and siloxy- or alkoxyhydrosilanes a

300 ast one oxygen-bearing function (hydroxyl or alkoxy) was required in the side chain for activity comp