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1 Concomitant disease-modifying therapies were allowed.

2 Fluorescent imaging using 6qcNIR allows 100% tumor margin assessment by generating en fac

3 ithms that benefit from expert knowledge and allow a biological understanding of their output.

4 y microsecond-timescale MD simulations, will allow a careful examination of the regulation of pLGICs

5 This surgical basket could allow a more standardized assessment of a country's surg

6 ding for motion and color, two features that allow a strong test of feature independence.

7 Such specialized secretion systems allow a variety of bacteria to thrive in specific host e

8 This study allowed a deep knowledge of the regioselectivity of the

9 The assay allowed a rapid and high-sensitive C. acutatum detection

10 would revolutionize the field of proteomics, allowing a more facile characterization of novel gene pr

11 This configuration allows a significant decrease of the uranium polyatomic

12 ion of Mus81-Mms4 to M phase but not S phase allows a wildtype response to various forms of replicati

13 ron reduction of heterocumulene moieties can allow access to unusual free carbene coordination geomet

14 Overall, this mechanism allows access to both traditional C-N adducts at room te

15 This position allows accommodation of the duplication of multilocus re

16 of association networks is refined with age, allowing accurate prediction of unseen individuals' brai

17 ng of methoxy groups into other nucleophiles allowed achieving alkene difunctionalization with the co

18 stness in biological systems is important to allow adaptation while maintaining essential functions.

19 halves in many eukaryotic ABC transporters, allowing all four consensus functional domains to be lin

20 w LsrK inhibitors have been reported so far, allowing ample room for further exploration.

21 This technique may allow an additional option to providers to remove comple

22 Enantioselective C(sp(3))-H aminations allow an efficient access to nonracemic chiral amines.

23 The strategy allowed an improvement in the number of KT in small chil

24 Remarkably, strain allows an ultrasensitive magnetization reversal to be ac

25 sights into the forces and interactions that allow and limit active-site motions.

26 Although this capacity partly allows animals and plants to acutely adapt to oxygen dep

27 se computational and experimental approaches allow assessment of critical microenvironmental signals

28 ctor binding and remodeling the Il9 locus to allow BATF binding in both mouse and human Th9 cultures.

29 -based restricted maximum likelihood (GREML) allow both fixed and random effects.

30 These strategies allow C-C bond formations in a regioselective manner to

31 This new method allowed calculation of kinetic features of these metabol

32 bset of HER2(+) breast cancer cell lines and allow cancer cells to proliferate in the presence of the

33 vity of the electron probe, our method would allow capturing the electronic dynamics of a wide range

34 insights into the molecular mechanisms that allow cells to change shape and move without tearing tis

35 tiered response to ribosome collisions would allow cells to dynamically tune translation rates while

36 tation had overgrown around the fence, hence allowing chameleons to cross.

37 or those patients who truly need them versus allowing clinicians some time for rapid investigation to

38 The electrode also allows coculturing with Shewanella for syntrophic electr

39 t inhibition that simplifies assay setup and allows comparison of inhibition models is discussed.

40 the rapidly falling costs of sequencing now allows comparisons between multiple experiments to ident

41 te cores binding elemental iron more tightly allow complete iron replacement within 15-60 min in one

42 wnregulation of GRK2 in the liver is key for allowing complete glucagon-mediated responses and effici

43 The rate-detection mechanism allows continuous stimulus sampling over a wide dynamic

44 The use of glutaconaldehyde also allows control of the nature of the counterion of the py

45 This allows controlled overexpression and repression of all g

46 ical limits, thus providing a tool that will allow decision-makers to evaluate the relative risk of d

47 urimazine, whose enhanced aqueous solubility allows delivery of higher doses to mice.

48 ted peripheral positioning of late endosomes allows delivery of SRC proto-oncogene, nonreceptor tyros

49 We sought to allow description of the complexity of IgE, IgG(4), and

50 bels DSBs with single-nucleotide resolution, allows detection of ultrarare breaks, takes 5 d to compl

51 for the formation of the quaternary center, allowing different substitution patterns on the aromatic

52 peated observations for the same individuals allow disentangling age patterns from idiosyncratic vari

53 This assay allows distinction of two separate binding sites for BOD

54 t the higher nucleotide concentration, which allows DnaA oligomerization at the replication origin bu

55 Nanotube transfer of GNLY allows dNK to protect against infection while leaving th

56 ied to allow estimation of rate ratios or to allow each person to serve as his/her own control (as we

57 This approach also allows easy phase transfer of the PQDs from nonpolar med

58 we develop a dCas9/CRISPR-based system that allows ectopic targeting of Ctf19c-subunits.

59 ection to clear the template of ribosomes to allow efficient replication.

60 odel pretrained on Fourier spectrum features allows efficient classification of electrograms recordin

61 The high level of degeneracy allows encoding 36 colours with 7 nodes by site-specific

62 nd analysis methods were further modified to allow estimation of rate ratios or to allow each person

63 n are enhanced when charge redistribution is allowed, even though charge injection happens at a posit

64 c inhibition (PSI) is centrally modulated to allow execution of supraspinal motor commands, it may be

65 s a web portal and a standalone R package to allow experimental and computational scientists to easil

66 In addition, the approach allows exquisite control over the patterned substrate/cr

67 le-stranded and duplex DNA junction with the allowed extension in the 5'-to-3' polarity, while ScRad5

68 urther, the new SCNP resists uptake by cells allowing extracellular click chemistry to be performed.

69 Our platform also allows facile visualization of drug effects in vivo at s

70 hallenge remains to identify guidelines that allow fine-tuning of detergents for individual applicati

71 It will also allow for a better understanding of the immune response

72 )O heteronuclear correlation NMR experiments allow for a rapid identification and differentiation of

73 Tradeoff curves allow for a visualized understanding on the efficiency/f

74 Herein, we generated a mouse model that allow for activation of NF-kappaB specifically in oligod

75 nt in which DNA demethylation takes place to allow for active transcription.

76 However, published studies do not allow for any conclusion to be reached regarding the ben

77 ich often goes undetected in the clinic, may allow for bacterial survival and establishment of a rese

78 ts to produce efficient counting which could allow for dramatically increased volumetric and sample t

79 strategies detecting T-cell activation would allow for early diagnosis and possibly more effective ma

80 d provide a guide to downstream analyses and allow for exclusion of samples of poor quality.

81 Although chronic implants allow for high-quality, long-term recordings in preclini

82 ood in patients with rheumatoid arthritis to allow for longitudinal RNA sequencing (RNA-seq).

83 gradation process will at the same time also allow for resynthesis and adaptive chemical modification

84 Timely prediction of AKI in children can allow for targeted interventions, but the wealth of data

85 for whole-genome-sequencing (WGS) technology allow for the detection of single-nucleotide polymorphis

86 for further research in this area that will allow for the identification of unique biomarkers for ea

87 swift to derive in a clinical setting, will allow for the investigation of causality of abnormal blo

88 Altogether, these capillary-driven elements allow for the manipulation of samples and reagents with

89 Four key features of DVME that allow for the rapid collection of vapor samples under th

90 Such signals would allow for treatment stratification and optimization.

91 el shows that the implementation of this tax allowed for a 4 to 8 times larger projected impact again

92 ain, where electrical properties of the film allowed for application of the sensor as a working elect

93 The deep learning model allowed for fully automatic and robust segmentation of G

94 ity to profile tumors with a resolution that allowed for granular assessment of both tumor cells and

95 The connected chambers allowed for perfusion and enabled replication of pressur

96 Illumina sequencing has allowed for population-level surveys of transposable ele

97 The models allowed for residual familial aggregation of breast and

98 -adaptive mutations in the RV-A16 2C protein allowed for robust replication in cells expressing mSTIN

99 fic copy number and serial sampling analyses allowed for the detection and tracking of clonal and sub

100 Our molecular tuning allowed for the synthesis of molecules exhibiting strong

101 ion as it is a crucial state of this enzyme, allowing for a rapid response demanded by the biological

102 atmospheric moisture is a powerful strategy allowing for decentralized access to potable water.

103 ting neuropathy is a cost-effective strategy allowing for early POEMS diagnosis and potentially enabl

104 igned embryo traps and engineered a protocol allowing for efficient chemical exchange for hundreds of

105 154-fold in mucus and tissue, respectively, allowing for high-fidelity comparisons across biogeograp

106 e therapies may fail to target self-renewal, allowing for relapse.

107 copy can complete the protocol within 2-3 d, allowing for several pause points during the procedure.

108 sensor a clotting time analysis is applied, allowing for the accurate measurement of coagulation, pl

109 system showed good sensitivity and rapidity, allowing for the detection of as low as 0.063% (w/w) chi

110 and heterogeneous phenotypic manifestations, allowing for the identification of novel mutations, gene

111 n of glucose from mitochondrial respiration, allowing for the maintenance of ATP levels under conditi

112 action with the organozinc reagents, thereby allowing for the synthesis of cyclic and acyclic tetrasu

113 This allows for a classification of minimal autocatalytic mot

114 lectronic state-sensitivity of the technique allows for a complete mapping of molecular dissociation

115 hanistic models such those implementing GRNs allows for a more general class of response functions bu

116 Such correlation allows for a priori selection of parameters for any desi

117 automatized suspect screening workflow that allows for a rapid preannotation of HRMS data sets.

118 otation of TCR repertoire sequencing samples allows for annotating large datasets on-line.

119 The technology is scalable, and it allows for beam focusing and steering and for structured

120 ple alternative splicing events together and allows for better estimates of the abundance of producti

121 LK-DFBA allows for calculation of metabolite concentrations and

122 Our platform allows for control of the local losses inside the networ

123 characterization of BsAbs' epitopes not only allows for detailed understanding of their mechanism of

124 ed complementary staging modality which also allows for diagnostic confirmation when combined with fi

125 reness of tri-aspartate architectures, which allows for engineering such a selective multivalent meta

126 lumes and random access to the data and also allows for future sequencing and synthesis technologies,

127 ration of water molecules between the layers allows for ion exchange with 3d and 5f metal cations.

128 t discriminate between diverse cellular RNAs allows for its broad cellular functions.

129 T, G and C bases during DNA synthesis, which allows for labeling of replicating or repaired DNA.

130 ion in approximately half of the heart still allows for marked vulnerability to injury.

131 ECTs operate in the accumulation mode, which allows for much lower energy consumption in comparison t

132 re formed as secondary mineral phases, which allows for oxyanion partitioning, e.g., IO(3)(-) incorpo

133 ompatible with microtome sectioning, the TTA allows for parallel histology processing for the entire

134 reduction or avoidance of cold ischemia and allows for pretransplant measurement of function and met

135 Our method allows for sensitive quantification using liquid chromat

136 eds in the context of optical mapping, which allows for spurious and deleted cut sites to be accounte

137 The design allows for the formation of ordered arrays of reorientin

138 Improved understanding of myelin clearance allows for the identification of pathways that are poten

139 This method allows for the orthogonal acetalization of substrates wi

140 pecific class of deep learning-based methods allows for the prediction of regulatory effects per vari

141 opulation (tens to hundreds of droplets) and allows for the simultaneous sizing of a single droplet u

142 licity, mild conditions and broad scope, and allows for the synthesis of highly functionalized azetid

143 inputs into generic output sequences, which allows for the target recognition and signal generation

144 fully convolutional architecture is that it allows for training on small domains and evaluation on a

145 Developmental plasticity allows genomes to encode multiple distinct phenotypes th

146 mobile phase, and a suitable rinsing regime, allowed good reproducibility and maintenance of the equi

147 llular migration tracts in brain parenchyma, allowed high-content time-resolved imaging of cell migra

148 f single-cell RNA sequencing (scRNA-seq) has allowed high-resolution analysis of cell-type diversity

149 lack of knowledge regarding mechanisms that allow HIV-infected cells to persist in individuals durin

150 Here, we introduce a novel platform that allows IC-FPOP to occur in a sterile incubation system c

151 tly, there is a need for reliable tests that allow identification of individuals that have been infec

152 cross-immunity and antigenic mutations that allow immune escape impact influenza epidemic dynamics a

153 it programming, and erasing functions, which allow in-pixel image pre-processing.

154 the cycloaddition from subsequent steps and allow interception and characterization of this long hyp

155 tly, we built an open-access web application allowing investigators to estimate the degree of varianc

156 Here we study the neuronal circuitry that allows larval Drosophila melanogaster of either sex to n

157 ent orbital angular momentum modes of light, allowing lensless reconstruction and holographic videos

158 y, elimination of the O-fucose site on EGF12 allowed LFNG to inhibit JAG1-NOTCH2 activation, and O-fu

159 With minimal perturbation to cells, ECORE allows long-term optical recording over multiple days.

160 ty and lifetime signals were produced, which allow mapping of O(2) in the tissue within 20 s.

161 jor constraint to exercise capacity in COPD, allowing maximal muscle function to be attained and eval

162 Labeling in Cell culture (SILAC) approaches allow measurement of protein dynamics, including protein

163 develop a simple theoretical framework that allows measuring the relative strength of intraspecific

164 achieve high-quality data, thus potentially allowing more reliable fMRI findings.

165 "treatment stage migration" strategy, which allows moving to another treatment (generally the one th

166 roundings or raw materials, distillers could allow naturally occurring or commercially available micr

167 ces in DNA, RNA and protein composition that allow OGT prediction from genome sequence alone.

168 We propose an approach to allow one to increase the sensitivity of the potentiomet

169 reached petabyte scale, repositories do not allow one to perform online sequence searches, yet, such

170 Reinforcement learning allows organisms to predict future outcomes and to updat

171 aptation is the self-generated activity that allows participants to learn new sensorimotor schemes.

172 A strand-specific analysis of the data allowed pinpointing CodY-binding sites at close to singl

173 to clinical practice, this could potentially allow practicing cardiologists to accurately assess the

174 road reaction scope with different alcohols, allowing primary and secondary alcohols to be employed a

175 rly healing after orthopaedic trauma must be allowed prior to the initiation of exercise to achieve o

176 teral surfaces of the cholangiocyte channel, allowing proof-of-concept toxicity studies with the bili

177 the filter by micro-Raman spectroscopy will allow proper quantification of microplastics in complex

178 guided anatomic mapping and robotic ablation allows PV isolation with good chronic safety; PV isolati

179 mechanism by which the innate immune system allows rapid quality check of absorbed fluids to avoid i

180 The method allows rapid, nontoxic measurement of the three-dimensio

181 racts with RcsF and whether this interaction allows RcsF to reach the surface has remained unclear.

182 The platform also allowed recovery of ~450-900 IgG sequences from ~2,200 I

183 /SNF and ISWI family chromatin remodelers to allow recruitment of Pol II and entry to a promoter-prox

184 TrailMap allows region-based quantification of total axon content

185 in the skin could be independently tuned to allow release of adjuvants and antigen from days up to t

186 r proteins upon flattening of caveolae could allow release of specific lipids into the bulk PM.

187 to AZD1775 by abrogating replication arrest, allowing replication despite DNA damage.

188 egative regulator of macrophage phagocytosis allowing repression of rat macrophages by human CD47-pos

189 To this end, mouse skin infection models allow researchers to examine host immunity by investigat

190 t account for spatial variability while also allowing researchers to account for both individual- and

191 ne order of magnitude lower than the maximum allowed residue limit (MRL) of the studied coccidiostats

192 The ODInCas9 mouse allows robust and tunable genome editing granting flexib

193 l as a resonator in a tuned circuit, thereby allowing signals to be excited inside the cell, and for

194 The monolithic device allows simultaneous measurements of the orthogonal compo

195 edges, respectively, the interplay of which allows small flakes to be utilized as stabilizers with a

196 for viral load monitoring become crucial to allow specific diagnostics and the effective monitoring

197 some attachments from transient forces while allowing spindle remodeling, and chromosome movements, o

198 ing basic concepts about ultrasound imaging, allowing students to significantly improve their scores

199 It allows studying VOCs release upon reconstitution and sup

200 red promising to improve the sensibility and allow sulfopeptide identification in complex samples.

201 need for animal-derived matrices, while also allowing systematic variations to the hydrogel propertie

202 The correct diagnosis is crucial to allow the consideration of all possible management optio

203 networks dysregulated in human disease would allow the design of network-correcting therapies that tr

204 e isotope-labeled standards, these workflows allow the determination of endogenous protein concentrat

205 to control this important trait and further allow the development of molecular markers to utilise th

206 On the other hand, the method did not allow the generation of benzocyclobutene-1,2-dione from

207 crovessels, calcium imaging and optogenetics allow the investigation of pericyte and smooth muscle ce

208 This allowed the alkylated thiol-containing and UV-reduced cy

209 High nutrient concentrations allowed the bacteria to strongly alter the chemical envi

210 tane, with linear dialdehyde building blocks allowed the construction of two rare covalent organic fr

211 The fermentation process allowed the detoxification of the pulp from caffeine by

212 in developmental and stem cell biology have allowed the development of cell-replacement therapies th

213 The obtained results allowed the identification of a highly selective G-quadr

214 this strain, but overexpression of dapF(Ct) allowed the mutant to overcome growth inhibition.

215 zyl-1,2:4,5-di-O-isopropylidene-myo-inositol allowed the preparation of 11.

216 This indicated that the proposed strategy allowed the side arms of H(1)/H(2) to be sealed into the

217 associated with CcMADS19 repression, thereby allowing the activation of CiFT2 the following cold seas

218 midity preserves the tissue's water content, allowing the assembly of collagen fibrils to be imaged i

219 cadian reporter mice that are Cre dependent, allowing the circadian properties of genetically defined

220 This study used models allowing the convenient cell isolation from Ccl17(E/+) r

221 This biocatalyst closes an important gap in allowing the conversion of chitin into complex glycoside

222 pathway in MBn suppresses ARM consolidation, allowing the formation of PSD-LTM.

223 s a model, we uncover the in vivo mechanisms allowing the generation of two opposing apical epithelia

224 common ortho-fluoro-ethynylarene precursors, allowing the heteroatoms to be installed at the 1-positi

225 e chemical diversity displayed by heparin by allowing the longer and structurally diverse chains to i

226 ely helps to position Bax1 at the forked DNA allowing the nuclease domain to incise one arm of the fo

227 ly from synthetic oligonucleotides (oligos), allowing the optimization of thermodynamic properties to

228 rent reactivities at the 2- and 7-positions, allowing the synthesis of mixed/asymmetric derivatives.

229 ional control is a widespread mechanism that allows the cell to rapidly modulate gene expression in o

230 phthyllactic acid-based iodine(III)-catalyst allows the control of tertiary carbon-fluorine stereocen

231 Local motion in a visual scene allows the detection of prey or predator and predicts th

232 The addition of 0.6 equiv of ABTE allows the differentiation of several spiroglycol proton

233 The technique also allows the direct assessment of the efficiency of protec

234 electrodes, enzyme, and cotton wool filter, allows the fabrication of a novel electroanalytical plat

235 The developed oxygen atom transfer approach allows the generation of 1,3-oxazoles containing a varie

236 Although plasticity is a valuable trait that allows the human brain to rewire and recover from injury

237 in because of its structural stability which allows the protein charge in solution to be controlled v

238 water-compatible ruthenium(II) vinyl probes allows the rapid, selective and sensitive detection of e

239 graphy of the fluorescently labeled library, allows the relative affinities of glycan ligands to be r

240 Thus, this experimental platform allows the study of human tumor initiation, progression,

241 It allows the transition from a laboratory scale to scale-u

242 on as well as visualization of LD statistics allows the user to easily trace geographic allelic corre

243 The novel device allows the user to ionize an extended range of chemicals

244 enzymes that modify incompatible DNA ends to allow their ligation.

245 a vehicle, such as a nanoparticle, that will allow them to be taken up by the target cells and then r

246 undergo a metabolic switch to glycolysis to allow them to perform rapid plastic responses.

247 Dams were allowed to deliver normally to measure pregnancy and neo

248 ploiting the known CPMG spikelet frequencies allowed to probe the near-absence of quartz in commercia

249 enhanced late-life offspring production when allowed to reproduce, indicating that earlier mating can

250 skills, although the nature of the mechanism allowing to extract numerical information (i.e., numeros

251 Nernstian slope in one electrochemical cell allows to amplify the signal and associated response slo

252 short-term memory of the membrane potential allows to generate persistent firing when clusters of co

253 Our method allows to properly include, in continuous phylogeographi

254 traction of neutrophils, shown previously to allow transfer of nucleotides across membranes.

255 may result in good short-term outcomes that allow uneventful pregnancies.

256 gut-associated lymphoid tissues (GALTs) that allows unprecedented profiling of the adaptive immune sy

257 species' responses to climate dynamics will allow us to anticipate and manage future range shifts dr

258 ffects mediated through other drivers, would allow us to better predict population fates and design m

259 sition metal dichalcogenide heterostructures allow us to optically create and investigate low-energy

260 strain strongly for a specific word, they do allow us to predict some upcoming information.

261 However, approaches that allow us to probe G4s in living cells without perturbing

262 in concert with in situ (19)F NMR monitoring allow us to propose that the pyridone ligand plays a rol

263 2(5H)-furanone, and 4-methyl-2(5H)-furanone, allowed us for the first time to fully elucidate the iso

264 High-resolution confocal images allowed us to analyze AL innervations of the various rep

265 odel treefrogs and developed a pipeline that allowed us to assemble their complete amino acid and nuc

266 ed on the low concentration of nanoparticles allowed us to demonstrate the capability of TOF-SIMS to

267 nce results, based on longitudinal GPS data, allowed us to determine ideal habitat ratios (grassland:

268 croscopy (HS-AFM) and kinetic modeling which allowed us to determine that septin filament assembly wa

269 The data and spectra obtained allowed us to gain further insight into accurate identif

270 morphisms was applied to 290 isolates, which allowed us to identify 25 additional cases related to th

271 terative rounds of site-directed mutagenesis allowed us to identify 4 of 413 residues from TrpB that

272 Repeated injection of HoxB8 progenitors also allowed us to maintain stable circulating HoxB8 neutroph

273 These data have allowed us to map the electronic structures of this meta

274 luorescence is sensitive to viscosity, Coupa allowed us to precisely localize sites of mitochondria-l

275 This paradigm allowed us to simultaneously measure amputee subject and

276 the use of diamond nanoparticles in phantoms allowed us to tune the T1 value of the phantoms which op

277 ors and fragments by Escherichia coli PBP1B, allowing us to (a) identify recognition elements of tran

278 on FUS mutants in parallel to FUS knockout, allowing us to compare mutation-induced changes to genui

279 ength Abeta stereoselective cellular uptake, allowing us to decouple aggregation from cellular, recep

280 tunable in structure and sulfation pattern, allowing us to determine how heparanase recognizes HS su

281 model is performed in a Bayesian framework, allowing us to quantify uncertainty in the allocation of

282 at outperforms other existing predictors and allows us to classify 1,760 genes-which are currently un

283 Single-cell RNA-sequencing (scRNA-seq) allows us to dissect transcriptional heterogeneity arisi

284 and measure compartmentalized cAMP, and this allows us to estimate the range of effector activation.

285 by collecting two images simultaneously that allows us to excite water with stimulated Raman scatteri

286 in real time via an NMR-based approach that allows us to follow the steps that couple ATP turnover t

287 physical transport through disordered media allows us to formulate precise links between the statist

288 a with those of suitable reference compounds allows us to identify their specific isomeric form, incl

289 t membrane extract hydrogels (Matrigel) that allows us to measure contractile force from the shape of

290 with mass spectrometry (MS)-based proteomics allows us to obtain snapshots of molecular microenvironm

291 This powerful combination of techniques allows us to obtain valuable insights into structural, e

292 Single-molecule spectroscopy allows us to quantify the effects of crowding on a compr

293 This allows us to realize a regime of nearly ideal QD doping

294 del improves micrograph interpretability and allows us to solve 3D single particle structures of clus

295 o answer, but the novel coronavirus pandemic allows us to understand how partisan animus contributes

296 eview, we show that having so many materials allows us to use big-data methods as a powerful techniqu

297 her combination with fluorescence microscopy allows users to determine cells or regions of interest f

298 The reaction allows valuable regioselective C-H modification of these

299 ously during gastrointestinal peristalsis to allow visualization of the detailed structures of the GI

300 rades KRT10, increasing NR4A1 expression and allowing VZV replication and propagation.