ライフサイエンスコーパス: alpha-glucosidase

1 the glycogen-degrading lysosomal enzyme acid-alpha glucosidase.

2 also potent inhibitors of alpha-amylase and alpha-glucosidase.

3 ong natural inhibitors for alpha-amylase and alpha-glucosidase.

4 -robinobioside as the strongest inhibitor of alpha-glucosidase.

5 s an NAD(+)- and metal ion-dependent phospho-alpha-glucosidase.

6 colonies on this medium due to production of alpha-glucosidase.

7 by a deficiency of the lysosomal enzyme acid alpha-glucosidase.

8 are good covalent inhibitors of a GH13 yeast alpha-glucosidase.

9 lic mechanism-based covalent inhibitor of an alpha-glucosidase.

10 docking predicted a high affinity of CGA for alpha-glucosidase.

11 when coincubated with the recombinant human alpha-glucosidase.

12 crog/ml) displayed strong inhibition towards alpha-glucosidase.

13 nt to the extensive digestion by the mucosal alpha-glucosidases.

14 e roles of individual and collective mucosal alpha-glucosidases.

15 identical, functions with other cloned human alpha-glucosidases.

16 J-based iminosugar derivatives to inhibit ER alpha-glucosidases.

17 does not inhibit endoplasmic reticulum (ER) alpha-glucosidases.

18 mmalian and yeast origin than to other plant alpha-glucosidases.

19 3 of the C-ring was related to inhibition of alpha-glucosidases.

20 f altered glycosylation after treatment with alpha-glucosidase-1 inhibitor, N-butyldeoxynojirimycin (

21 Anthocyanin-rich extracts inhibited alpha-glucosidase (37.8%), alpha-amylase (35.6%), dipept

22 hibiting of pancreatic lipase (74.5%) and of alpha-glucosidase (98.2%).

23 The alpha-glucosidase, a member of GH31 family, shows substr

24 gainst enzymes with biological significance (alpha-glucosidase, acetylcholinesterase and butyrylcholi

25 his study was to investigate how the mucosal alpha-glucosidases act with alpha-amylase to digest gran

26 ir effect in inhibiting i) alpha-amylase and alpha-glucosidase activities and ii) colorectal cancer c

27 g a combination of alpha-amylase and mucosal alpha-glucosidase activities, were applied to three gran

28 and inhibitory effects on alpha-amylase and alpha-glucosidase activities.

29 by evaluating the lipase, alpha-amylase and alpha-glucosidase activities.

30 d with fluctuations in lysosomal and neutral alpha-glucosidase activities.

31 6pc(-/-) mice, pharmacological inhibition of alpha-glucosidase activity almost completely abolished r

32 ome monoterpenes inhibited alpha-amylase and alpha-glucosidase activity and stimulated glucose uptake

33 se-related changes in glycogen, glucose, and alpha-glucosidase activity are also found in spinal cord

34 A genotype does not affect the regulation of alpha-glucosidase activity by repressing sugars.

35 The inhibition of the alpha-amylase and alpha-glucosidase activity facilitates the maintenance o

36 The acidic alpha-glucosidase activity from broccoli flower buds was

37 es per cell) more than doubled the amount of alpha-glucosidase activity in cell extracts.

38 d sugars, and it completely eliminated CR of alpha-glucosidase activity in liquid medium.

39 gene, resulting in deficient lysosomal acid-alpha-glucosidase activity in patients, and a progressiv

40 Extracts with IC50 for alpha-glucosidase activity in the 0.010-0.079mgmL(-1) ra

41 rich extracts from certain berries inhibited alpha-glucosidase activity in vitro.

42 a-D-glucopyranoside revealed that the acidic alpha-glucosidase activity is predominantly located in t

43 le blood-based assay to measure the level of alpha-glucosidase activity is the optimal initial test f

44 n-regulated in the expression of MAL1, total alpha-glucosidase activity was not decreased in leaves a

45 Differential inhibition of alpha-amylase and alpha-glucosidase activity was observed in response to p

46 steps and the potential ability to modulate alpha-glucosidase activity were tested.

47 has the strongest inhibitory effect against alpha-glucosidase activity with IC(50) 0.08 +/- 0.002 mg

48 We show that alpha-glucosidase activity, i.e. glycogen debranching an

49 he function of a potato gene (MAL1) encoding alpha-glucosidase activity, transgenic plants in which M

50 sorghum and rye extracts inhibited (p<0.05) alpha-glucosidase activity, whereas barley and sorghum e

51 e activities of the three lysosomal enzymes (alpha-glucosidase (AG), beta-galactosidase (B-GAL) and b

52 Four glycosidases, alpha-glucosidase (AG), beta-glucosidase (BG), beta-xylo

53 an NAD(+) and metal ion-dependent 6-phospho-alpha-glucosidase (AglB).

54 a single primer (M13 core) and assessed for alpha-glucosidase (alpha-Glu) activity.

55 llular dehydrogenase (DHA) and extracellular alpha-glucosidase (alpha-Glu) and protease (PRO) enzymes

56 nd phytoprostanes (PhytoPs) on four enzymes: alpha-glucosidase, alpha-amylase, acetylcholinesterase,

57 The inhibition of alpha-glucosidase, alpha-amylase, and angiotensin-conver

58 The inhibition of alpha-glucosidase, alpha-amylase, lipase, cyclooxygenase

59 ssociated with metabolic syndrome, including alpha-glucosidase, amylase and lipase and exhibited anti

60 hysiological relevance of acid maltase (acid alpha-glucosidase, an enzyme that degrades lysosomal gly

61 st (p <= 0.05) in peel and pulp tissues (85% alpha-glucosidase and 8% alpha-amylase inhibition).

62 d (150 rpm), significantly (p < 0.05) higher alpha-glucosidase and acetylcholinesterase inhibition ac

63 ntioxidant activities for free fraction, and alpha-glucosidase and acetylcholinesterase inhibition fo

64 dical scavenging activity and alpha-amylase, alpha-glucosidase and aldose reductase inhibitory activi

65 nds and the inhibitory effect of extracts on alpha-glucosidase and alpha-amylase activities were inve

66 olyphenols from guarana were able to inhibit alpha-glucosidase and alpha-amylase activities.

67 For this purpose, alpha-glucosidase and alpha-amylase assays were assessed

68 lloylated glucoses were studied as potential alpha-glucosidase and alpha-amylase inhibitors.

69 ong with evaluation of in vitro antioxidant, alpha-glucosidase and alpha-amylase inhibitory activitie

70 of Verdolino extracts exhibited the highest alpha-glucosidase and alpha-amylase inhibitory activity

71 , which can be counteracted by inhibition of alpha-glucosidase and alpha-amylase, both involved in th

72 strong antioxidant activities, inhibition of alpha-glucosidase and alpha-amylase, inhibition of angio

73 Western blot analysis using anti-alpha-glucosidase and anti-beta-glycosidase antibodies i

74 Phospho-alpha-glucosidase and EIIA are encoded by genes at the L

75 higher capacity in inhibiting alpha-amylase, alpha-glucosidase and HT29 cell growth.

76 lipase and comparable and lower activity on alpha-glucosidase and hyaluronidase, respectively.

77 wed the highest inhibition of alpha-amylase, alpha-glucosidase and lipase (IC50: 0.38mg/mL, 0.87mug/m

78 ced LDL-cholesterol peroxidation, as well as alpha-glucosidase and lipase activities were demonstrate

79 power as well as evaluation of inhibition of alpha-glucosidase and lipase activities.

80 syndrome-associated enzymes (alpha-amylase, alpha-glucosidase and lipase) was evaluated.

81 daria pinnatifida has a potential to inhibit alpha-glucosidase and may be used as a bioactive food in

82 the deficiency of the lysosomal enzyme acid alpha-glucosidase and results in cellular lysosomal and

83 Phospho-alpha-glucosidase and sucrose-6-phosphate hydrolase exhi

84 inhibitory activities towards alpha-amylase, alpha-glucosidase and tyrosinase.

85 samples inhibited the enzymes alpha-amylase, alpha-glucosidase and xanthine oxidase.

86 lustat (Zavesca)] based on the inhibition of alpha-glucosidases and glucosyltransferases.

87 sults for hSGLT3 are compared with those for alpha-glucosidases and human SGLT type 1 (hSGLT1), a wel

88 arch is unexpectedly associated with mucosal alpha-glucosidases and not just alpha-amylase.

89 ng-alkyl-chain DNJ derivatives to inhibit ER alpha-glucosidases and their antiviral effect, ruling ou

90 oxidant activity, and greater alpha-amylase, alpha-glucosidase, and ACE inhibitory activity than the

91 trong inhibitory potential of alpha-amylase, alpha-glucosidase, and dipeptidyl peptidase III (DPP III

92 was distinct for antioxidant activity, ACE-, alpha-glucosidase-, and Kunitz trypsin-inhibitory activi

93 . meliloti possesses at least one additional alpha-glucosidase as well as a lower-affinity transport

94 oscopy, i.e., HPLC-SPE-ttNMR/high-resolution alpha-glucosidase assay.

95 act showed promising results as inhibitor of alpha-glucosidase, being almost 9 times more effective t

96 High-resolution alpha-glucosidase biochromatograms of these extracts all

97 ing characteristics are similar to those for alpha-glucosidases, but there are no interactions with h

98 gh the toggling of activities of the mucosal alpha-glucosidases by selective enzyme inhibition.

99 loned human alpha-glucosidase (human neutral alpha-glucosidase C or GANC) is a previously uncharacter

100 Thus, mucosal alpha-glucosidases can have a synergistic effect with al

101 Phospho-alpha-glucosidase catalyzed the hydrolysis of a wide var

102 eolysis of intact viral capsid proteins, the alpha-glucosidase-catalyzed hydrolysis of p-nitrophenyl-

103 Mutations in alpha-glucosidase cause accumulation of glycogen in lyso

104 ase (PD) is a metabolic myopathy due to acid alpha-glucosidase deficiency and characterized by extens

105 ical cloning of two alleles of human neutral alpha-glucosidase (designated GANC on the human gene map

106 PR-mediated uptake of recombinant human acid-alpha-glucosidase during ERT in mice with Pompe disease

107 dies detected 101 and 95 kDa forms of barley alpha-glucosidase early in seed germination.

108 S. sanguis IUOM-11M alpha-glucosidase (EC 3.2.1.20) demonstrated a pH optimu

109 uorogenic substrate is a useful tool for the alpha-glucosidase enzyme assay and will facilitate compo

110 eveloped a new fluorogenic substrate for the alpha-glucosidase enzyme assay, resorufin alpha-d-glucop

111 racts showed more than 80% inhibition of the alpha-glucosidase enzyme at a concentration of 40mg/mL (

112 e is the least studied of the membrane-bound alpha- glucosidase enzymes.

113 UV-4B is an iminosugar that inhibits the alpha-glucosidase family of enzymes and subsequently the

114 he unique and shared roles of the individual alpha-glucosidases for alpha-glucans persisting after st

115 s the most potent (IC50: 0.25mug/mL) against alpha-glucosidase; Fraction IV from black turtle bean wa

116 nment with its homologs, the novel 6-phospho-alpha-glucosidase from B. subtilis can be assigned to th

117 found to be low micromolar inhibitors of the alpha-glucosidase from baker's yeast with Ki's near to 2

118 h polyclonal rabbit antibody against phospho-alpha-glucosidase from Fusobacterium mortiferum.

119 and the enzymatic activity of a recombinant alpha-glucosidase from human gut bacterium Ruminococcus

120 utation in the active site of the homologous alpha-glucosidase from Sulfolobus solfataricus resulted

121 ly, we also found that, unlike mammals, acid alpha-glucosidase from zebrafish and medaka does not app

122 the glycogen-degrading lysosomal enzyme acid alpha -glucosidase (GAA) (also called "acid maltase"), c

123 bolic disorder characterized by lack of acid-alpha glucosidase (GAA) resulting in ubiquitous lysosoma

124 f lysosomal glycogen-hydrolyzing enzyme acid alpha-glucosidase (GAA) activity, which results in lysos

125 Acid alpha-glucosidase (GAA) cleaves the alpha1-4 and alpha1-

126 s primarily the liver and kidney, while acid alpha-glucosidase (GAA) deficiency in GSD II causes prim

127 Enzyme or gene replacement therapy with acid alpha-glucosidase (GAA) has achieved only partial effica

128 sported to and degraded in lysosomes by acid alpha-glucosidase (GAA) in mammals, but it is unclear wh

129 Acid alpha-glucosidase (GAA) is a lysosomal enzyme that degra

130 Acid alpha-glucosidase (GAA) is a lysosomal enzyme that hydro

131 of a modified Ad vector encoding human acid alpha-glucosidase (GAA) resulted in efficient hepatic tr

132 erated by treating the lysosomal enzyme acid alpha-glucosidase (GAA) with recombinant GlcNAc-phosphot

133 e II (GSDII), caused by a deficiency in acid alpha-glucosidase (GAA), leads to lysosomal accumulation

134 IOPD), caused by mutations in lysosomal acid alpha-glucosidase (Gaa), manifests rapidly progressive f

135 cardiomyopathy caused by deficiency of acid alpha-glucosidase (GAA), skeletal muscle seems an obviou

136 system to improve lysosomal delivery of acid alpha-glucosidase (GAA), the enzyme deficient in patient

137 s directly related to the deficiency of acid alpha-glucosidase (GAA), which degrades glycogen in the

138 esisted enzyme replacement therapy with acid alpha-glucosidase (GAA), which has been attributed to in

139 rior muscles of young-, mid-, and late-stage alpha-glucosidase (GAA)-deficient mice.

140 d by deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA).

141 by a deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA).

142 The phospho-alpha-glucosidase gene (aglB) lies adjacent to a second

143 expression and regulation of the human acid alpha-glucosidase gene as well as other lysosomal enzyme

144 previously demonstrated that the human acid alpha-glucosidase gene expression is regulated by a sile

145 steady-state expression level of the potato alpha-glucosidase gene was low in most tissues examined,

146 Arabidopsis contains at least three alpha-glucosidase genes; Aglu-1 and Aglu-3 are sequenced

147 -center structure with that of the 6-phospho-alpha-glucosidase GlvA from Bacillus subtilis reveals a

148 OH led to an increase of 10% in both alpha-glucosidase (>99%) and alpha-amylase (>=70%).

149 ements confirmed their high affinity towards alpha-glucosidase, highlighting a static quenching mecha

150 e hypothesized that an as-yet uncloned human alpha-glucosidase (human neutral alpha-glucosidase C or

151 wo siblings with a rare genetic defect in ER alpha-glucosidase I (ER Glu I) who showed resistance to

152 Processing alpha-glucosidase I (GluI) is a key member of the eukary

153 pha-glucosidase I may have a small amount of alpha-glucosidase I activity in vivo based on the low le

154 Chinese hamster ovary cells are defective in alpha-glucosidase I activity, which removes the distal a

155 tro assays of each enzyme gave no detectable alpha-glucosidase I activity.

156 omimetic that inhibits endoplasmic reticulum alpha-glucosidase I and II enzymes resulting in improper

157 ereas the S440F mutation largely inactivates alpha-glucosidase I both in vitro and in vivo.

158 charide glucosidase (OsMOGS), an ortholog of alpha-glucosidase I in Arabidopsis, which trims the term

159 However, the S440F alpha-glucosidase I may have a small amount of alpha-glu

160 of knf embryos demonstrated that KNF encodes alpha-glucosidase I, the enzyme that catalyzes the first

161 xtract was particularly active against yeast alpha-glucosidase (IC(50) = 1.53 mug/mL), acting through

162 bsorbance capacity and effectively inhibited alpha-glucosidase (IC(50): 0.83 mg/ml) and pancreatic li

163 hibition (alpha-amylase: IC(50)-42.34 ug/mL; alpha-glucosidase: IC(50):63.89 ug/mL), basal uptake of

164 chickpea showed inhibitory activity against alpha-glucosidase (IC50 6967 +/- 343 and 2885 +/- 85.4 m

165 mug/ml (bran) and 148.23 mug/ml (hulls)] and alpha-glucosidase [IC50, 62.1 mug/ml (bran) and 68.14 mu

166 ystal structures of the main ERQC enzyme, ER alpha-glucosidase II (alpha-GluII; from mouse), alone an

167 more similar to the glycoprotein-processing alpha-glucosidase II of mammalian and yeast origin than

168 , as well as a decrease in the inhibition of alpha-glucosidase in both extracts, when compared to und

169 dicate a unique role for the S. solfataricus alpha-glucosidase in carbohydrate metabolism.

170 n markedly enhanced expression of human acid-alpha-glucosidase in nonhuman primates.

171 to phosphorylate a lysosomal hydrolase, acid alpha-glucosidase in vitro.

172 alpha-Amylase combined with the mucosal alpha-glucosidases in the intestinal extract showed high

173 d pancreatic alpha-amylases and four mucosal alpha-glucosidases, including N- and C-terminal subunits

174 vefold range of dietary NSP intake, although alpha-glucosidase increased on a resistant starch-enrich

175 N-terminal sequence from the 96-kD broccoli alpha-glucosidase indicated that it corresponds to the A

176 iated uptake because alpha-l-iduronidase and alpha-glucosidase induced tolerance with the drug regime

177 iched in tannins (16C) induced a more potent alpha-glucosidase inhibition (pIC(50) = 5.3 +/- 0.1).

178 nce regarding the in vitro alpha-amylase and alpha-glucosidase inhibition activities of extracts deri

179 parameters that affect the alpha-amylase and alpha-glucosidase inhibition activities of the extracts.

180 ds have been shown to have alpha-amylase and alpha-glucosidase inhibition activities.

181 However, no alpha-glucosidase inhibition activity was observed under

182 alpha-Glucosidase inhibition activity, cell viability an

183 m of this study was to evaluate the in vitro alpha-glucosidase inhibition and antioxidant activity of

184 m of this study was to evaluate the in vitro alpha-glucosidase inhibition and antioxidant activity of

185 In in vitro alpha-glucosidase inhibition and antioxidant activity, t

186 radical scavenging, beta-carotene bleaching, alpha-glucosidase inhibition and greatest amount of TPC.

187 cavenging, beta-carotene bleaching activity, alpha-glucosidase inhibition and the highest total pheno

188 es and their antiviral effect, ruling out ER alpha-glucosidase inhibition as the sole mechanism respo

189 d acetone extracts of seaweeds were used for alpha-glucosidase inhibition assay hyphenated with high

190 alytical platform based on a high-resolution alpha-glucosidase inhibition assay in combination with h

191 multivariate data analysis, high-resolution alpha-glucosidase inhibition assays and HPLC-HRMS-SPE-NM

192 anol extract of H. biflora (HBMe) showed 50% alpha-glucosidase inhibition at the concentration of 480

193 The alpha-glucosidase inhibition in FL was higher than that

194 cular docking was carried out to investigate alpha-glucosidase inhibition mechanisms.

195 rthermore investigated using high-resolution alpha-glucosidase inhibition profiling combined with hig

196 bition) activity, however, a 10% increase in alpha-glucosidase inhibition was observed in irradiated

197 30-50% alpha-glucosidase inhibition was observed in ultrasound,

198 Therefore, the combination of alpha-glucosidase inhibition with its antiradical capaci

199 observed on antidiabetic (alpha-amylase and alpha-glucosidase inhibition) activity, however, a 10% i

200 fits (anticancer activity, alpha-amylase and alpha-glucosidase inhibition, angiotensin-converting-enz

201 s investigated, as well as alpha-amylase and alpha-glucosidase inhibition, antihypertensive, antioxid

202 a significant potential to use as a natural alpha-glucosidase inhibition, antioxidant agent.

203 on nullified roasting-induced differences in alpha-glucosidase inhibition, CGA showed a decreasing tr

204 brews were in vitro digested and tested for alpha-glucosidase inhibition, to explore their antidiabe

205 e used for pinpointing HPLC peaks displaying alpha-glucosidase inhibition.

206 and also showed a high (~ 98%) potential for alpha-glucosidase inhibition.

207 Water fraction (WF) of ME was a stronger alpha-glucosidase inhibitor (EC50 2.9 mug/mL) than querc

208 itor (SMD, 0.33 [95% CI, 0.13 to 0.52]), and alpha-glucosidase inhibitor (SMD, 0.35 [95% CI, 0.12 to

209 The effect of the alpha-glucosidase inhibitor acarbose on cardiovascular o

210 oselective synthesis of nectrisine, a potent alpha-glucosidase inhibitor, was carried out starting fr

211 WF was a competitive alpha-glucosidase inhibitor.

212 s the increased amount of quercetin, a known alpha-glucosidase inhibitor.

213 therapeutic target for type II diabetes, and alpha-glucosidase inhibitors have been used in the clini

214 Nateglinide and alpha-glucosidase inhibitors may have slightly weaker ef

215 Alpha-glucosidase inhibitors play a potential role in th

216 antioselective total synthesis of the potent alpha-glucosidase inhibitors schulzeine A, B, and C and

217 Previous studies have suggested that alpha-glucosidase inhibitors such as castanospermine and

218 these phenolic sub-classes were more potent alpha-glucosidase inhibitors than the clinical drug, aca

219 7-2.08 kg), glucagon-like peptide-1 analogs, alpha-glucosidase inhibitors, and dipeptidyl peptidase-4

220 , more expensive agents (thiazolidinediones, alpha-glucosidase inhibitors, and meglitinides), older a

221 by structural identification targeted these alpha-glucosidase inhibitors, as demonstrated by a proof

222 sulins, sulfonylureas, glinides, biguanides, alpha-glucosidase inhibitors, thiazolidinediones, glucag

223 primarily by adding or adjusting metformin, alpha-glucosidase inhibitors, thiazolidinediones, or ins

224 a natural source of potent antioxidants and alpha-glucosidase inhibitors.

225 n efficient method for the identification of alpha-glucosidase inhibitors.

226 izidines revealed to be potent and selective alpha-glucosidase inhibitors.

227 The alpha-glucosidase inhibitory activities of the VJ and FV

228 C50 values following fermentation, while the alpha-glucosidase inhibitory activities ranged from 95.2

229 E. maxima were evaluated for antiradical and alpha-glucosidase inhibitory activities.

230 isolates were evaluated for antioxidant and alpha-glucosidase inhibitory activities.

231 ion of X2C gave a subfraction, with enhanced alpha-glucosidase inhibitory activity (IC50=6.15mug/mL),

232 HR-bioassay/HPLC-HRMS-SPE-NMR showed the alpha-glucosidase inhibitory activity of A. nodosum, F.

233 The antioxidant capacity and the alpha-glucosidase inhibitory activity of the duodenal ex

234 ebaudioside-A showed concentration-dependent alpha-glucosidase inhibitory activity with IC50=35.01 mu

235 d fast identification of three analytes with alpha-glucosidase inhibitory activity, and subsequent HP

236 Samples showing more than 60% alpha-glucosidase inhibitory activity, at a concentratio

237 cies were screened for their antioxidant and alpha-glucosidase inhibitory activity.

238 the development of new functional foods with alpha-glucosidase inhibitory activity.

239 y (DPPH), polyphenol content (GAE) and yeast alpha-glucosidase inhibitory activity.

240 atform enables fast screening for individual alpha-glucosidase inhibitory analytes in complex matrice

241 plausibly due to the presence of intestinal alpha-glucosidase inhibitory and augmenting cellular glu

242 e extracts of seaweeds for alpha-amylase and alpha-glucosidase inhibitory effects.

243 strated stronger antioxidant activity and an alpha-glucosidase inhibitory property than positive cont

244 le and lemon myrtle fractions had pronounced alpha-glucosidase-inhibitory activities (IC(50): 0.30 an

245 In addition, alpha-glucosidase is a therapeutic target for type II di

246 Inhibition of alpha-amylase and/or alpha-glucosidases is a strategy for treatment of type 2

247 e 2 diabetes framework, the extract inhibits alpha-glucosidase (K(i) = 166.9 ug/mL) and aldose reduct

248 a6/Delta6), like the recently published acid alpha-glucosidase knockout with disruption of exon 13, h

249 influences glucose generation at the mucosal alpha-glucosidase level.

250 l-NBDNJ is able to enhance lysosomal alpha-glucosidase levels in Pompe disease fibroblasts, e

251 metabolic syndrome, including alpha-amylase, alpha-glucosidase, lipase and hydroxyl methyl glutaryl C

252 The specific activities of three enzymes, an alpha-glucosidase (malA), a beta-glycosidase (lacS), and

253 s of three glycosyl hydrolases, including an alpha-glucosidase (malA), a beta-glycosidase (lacS), and

254 nolic compounds did not affect inhibition of alpha-glucosidase (maltase) activity, which remained rel

255 in turn hydrolyzed to glucose by the mucosal alpha-glucosidases, maltase-glucoamylase (MGAM) and sucr

256 In vitro digested coffee inhibited alpha-glucosidase more effectively, compared to undigest

257 ith flaviviruses (for example, V-ATPases and alpha-glucosidases), most of the DVHFs were newly implic

258 nated malR, which regulates expression of an alpha-glucosidase not controlled by SusR.

259 Apoplastic alpha-glucosidases occur widely in plants but their func

260 se-6'-phosphate hydrolase (MalH) and phospho-alpha-glucosidase (PagL), respectively.

261 capacities and inhibitory activities against alpha-glucosidase, pancreatic lipase and angiotensin I-c

262 extract and its inhibiting activity against alpha-glucosidase, pancreatic lipase and hyaluronidase w

263 tion, enzymatic in vitro inhibition tests of alpha-glucosidase, pancreatic lipase, acetylcholinestera

264 terase), anti-diabetic (anti-alpha-amylase, -alpha-glucosidase, -pancreatic lipase) and antioxidant p

265 he ethyl acetate fraction inhibited in vitro alpha-glucosidase (pIC(50) = 4.8 +/- 0.1), an enzyme inv

266 vels of the full-length GAA transcript, acid-alpha-glucosidase protein, and enzyme activity in all pa

267 Only the mucosal alpha-glucosidases provide the final hydrolytic activiti

268 CCR of maltose-inducible alpha-glucosidase, raffinose-inducible alpha-galactosida

269 ose 6-phosphate hydrolase) and pagl (phospho-alpha-glucosidase), respectively, reside in separate ope

270 atively high doses of recombinant human acid alpha-glucosidase (rhGAA) may be required to reduce the

271 idase, and the 1-nonylazetidine 25 inhibited alpha-glucosidase (Saccharomyces cerevisiae) with an IC(

272 All four alpha-glucosidases share digestion of linear regions of

273 s of alpha-amylase, but potent inhibitors of alpha-glucosidase, showing low-micromolar IC(50) values,

274 ibition properties against alpha-amylase and alpha-glucosidases, showing different inhibition constan

275 via their ability to inhibit alpha-amylase, alpha-glucosidase, sodium-glucose transporters, and panc

276 The IC(50) values show that the four alpha-glucosidase subunits could be differentially inhib

277 wed superior inhibition of alpha-amylase and alpha-glucosidase than foxtail millet cultivars.

278 se (SI) is an intestinal membrane-associated alpha-glucosidase that breaks down di- and oligosacchari

279 lB is an unusual NAD+/Mn2+-dependent phospho-alpha-glucosidase that promotes growth of MG-1655 (pAP1)

280 , Mn2+, and dithiothreitol-dependent phospho-alpha-glucosidases that can be assigned to family 4 of t

281 copyranosyl:phosphoglucohydrolase (6-phospho-alpha-glucosidase) that requires both NAD(H) and divalen

282 Acid alpha-glucosidase, the product of a housekeeping gene, i

283 beginning with alpha-amylase and followed by alpha-glucosidase to produce glucose.

284 o GID of the samples, only the inhibition of alpha-glucosidase was preserved.

285 Enzymatically active, recombinant alpha-glucosidase was synthesized and secreted from the

286 Inhibition of alpha-amylase and alpha-glucosidase was the highest at 65 and 85 degrees C

287 ular starch by mammalian recombinant mucosal alpha-glucosidases was observed which shows that these e

288 ibitory properties against alpha-amylase and alpha-glucosidase were investigated.

289 nd lysosomal acid maltase, two major hepatic alpha-glucosidases, were unaltered in L-G6pc(-/-) mice,

290 ese residues were not acquired on human acid alpha-glucosidase when expressed in zebrafish embryos, s

291 y measuring its activation by an ER resident alpha-glucosidase, which is dependent on entry into the

292 P generated uncompetitive inhibitors against alpha-glucosidase, while EAEP, AEP, and HEX-AEP (used as

293 system, and one (aglA) appears to encode an alpha-glucosidase with homology to family 13 of glycosyl

294 ample of fucoxanthin significantly inhibited alpha-glucosidase with IC(50) value 0.047 +/- 0.001 mg/m

295 from black currant and rowanberry, inhibited alpha-glucosidase with IC(50) values respectively of 20

296 nnaeus were found to be potent inhibitors of alpha-glucosidase with IC50 values of 0.32 and 0.49 mug/

297 s were found to be potent inhibitors of rice alpha-glucosidase with K(i) and IC(50) values in the nan

298 ysosomal enzymes alpha-l-iduronidase or acid alpha-glucosidase with the receptor-associated protein w

299 two commercial samples were able to inhibit alpha-glucosidase, with EC(50) values lower than that fo

300 Fractions X1C and X2C notably inhibited alpha-glucosidase, with IC50=9.89 and 8.05mug/mL, respec