ライフサイエンスコーパス: alpha-linolenic acid

1 in essential fatty acids (alpha-linoleic and alpha-linolenic acids).

2 nfidence interval, 0.42 to 0.88) for dietary alpha-linolenic acid.

3 y-18:2Delta(9,15)) in cultures supplied with alpha-linolenic acid.

4 ts products, all of which are metabolites of alpha-linolenic acid.

5 atidylserine, sphingomyelin derivatives, and alpha-linolenic acid.

6 ations were seen with the 18-carbon omega-3, alpha-linolenic acid.

7 eic acid and by increasing the proportion of alpha-linolenic acid.

8 Major fatty acids were linoleic acid and alpha-linolenic acid.

9 cid linoleic acid and the omega-3 fatty acid alpha-linolenic acid.

10 recursor 12-oxophytodienoic acid (OPDA) from alpha-linolenic acid.

11 the exclusive presence of linoleic acid and alpha- linolenic acid.

12 atty acids (EFA), arachidonic, linoleic, and alpha-linolenic acids.

13 tial fatty acids, arachidonic, linoleic, and alpha-linolenic acids.

14 antly higher levels of stearic, behenic, and alpha-linolenic acids.

15 dical-catalyzed nonenzymatic peroxidation of alpha-linolenic acid (1).

16 vealed high levels of linoleic acid (4.72%), alpha-linolenic acid (10.8%) and phytols (12.0%), as wel

17 12-HETE), linoleic acid (12,13-DiHOME), and alpha-linolenic acid (16-HOTrE).

18 Higher intake levels of alpha-linolenic acid (18:3 n-3) were correlated with low

19 nent exception being a relative reduction in alpha-linolenic acid (18:3(cisDelta9,12,15)) in both the

20 fatty acids (PUFAs) linoleic acid (18:2) and alpha-linolenic acid (18:3) in triacylglycerols (TAG) ar

21 entified the major chloroplast galactolipid: alpha-linolenic acid (18:3)-7Z,10Z,13Z-hexadecatrienoic

22 ry was noticed in the concentration level of alpha-linolenic acid (18:3, ALA), arachidonic acid (20:4

23 t the n-3 fatty acids, the concentrations of alpha-linolenic acid (18:3n-3) and docosahexaenoic acid

24 tty acids (EFAs) linoleic acid (18:2n-6) and alpha-linolenic acid (18:3n-3) in children, who need EFA

25 n laboratory animals and humans suggest that alpha-linolenic acid (18:3n-3) may reduce the risk of ar

26 h the levels for linoleic acid (18:2n-6) and alpha-linolenic acid (18:3n-3) remained unaltered, there

27 From these studies it appeared that alpha-linolenic acid (18:3n-3) was equivalent to n-6-ric

28 This process leads to selective losses of alpha-linolenic acid (18:3n-3).

29 [U-(13)C]-alpha-Linolenic acid (18:3n-3, ALA) was thermally oxidiz

30 Because alpha-linolenic acid (18:3n-3; ALA) is the direct precur

31 ns of plasma linoleic acid (18:2n-6; LA) and alpha-linolenic acid (18:3n-3; ALA).

32 erythrocytes, r(s)=0.24; plasma, r(s)=0.25), alpha-linolenic acid (18:3n-3; erythrocytes, r(s)=0.18;

33 CO is high in alpha-linolenic acid (18:3omega3, ALA) (30%), with an om

34 lect dietary intake (linoleic acid, 18:2n-6; alpha-linolenic acid, 18:3n-3; eicosapentaenoic acid, 20

35 SI had high alpha-linolenic acid (53.8%), linoleic acid (33.4%) and

36 c acid, 6 of 8 dogs were protected, and with alpha-linolenic acid, 6 of 8 dogs were also protected (P

37 soluble dietary fibres (74%), ash (51%), and alpha-linolenic acid (67.4%).

38 by the diet or endogenous biosynthesis from alpha-linolenic acid, accretes during the perinatal brai

39 athway regulate CsFAD3 expression and affect alpha-linolenic acid accumulation.

40 s to determine whether vegetable oil-derived alpha-linolenic acid added to a diet enriched in n-6 fat

41 d by (13)C nuclear magnetic resonance (NMR), alpha-linolenic acid (ALA) and docosapentaenoic acid (DP

42 tituents such as gamma-linolenic acid (GLA), alpha-linolenic acid (ALA) and stearidonic acid (SA), as

43 d the association between the n-3 fatty acid alpha-linolenic acid (ALA) and the incidence of congesti

44 revious studies indicated that the intake of alpha-linolenic acid (ALA) can alter the concentration o

45 The maximum alpha-linolenic acid (ALA) content was 33 +/- 1%.

46 Due to alpha-linolenic acid (ALA) contents below 1% of total fa

47 d diets containing 3.5% or 5.3% of energy as alpha-linolenic acid (ALA) for two consecutive 14-wk per

48 ll and concentrations of total n-3 PUFAs and alpha-linolenic acid (ALA) in erythrocytes, which were o

49 (P < 0.000001), whereas the availability of alpha-linolenic acid (ALA) increased from 0.39% to 0.72%

50 ncrement: 0.99; 95% CI: 0.88, 1.10], whereas alpha-linolenic acid (ALA) intake was inversely associat

51 alpha-Linolenic acid (ALA) is an n-3 (omega-3) fatty aci

52 alpha-Linolenic acid (ALA) is associated with a low risk

53 A large proportion of dietary alpha-linolenic acid (ALA) is oxidized, and because of l

54 tabolites within the linoleic acid (LNA) and alpha-linolenic acid (ALA) metabolism pathways, (3) a ca

55 y supplementation with the vegetable omega-3 alpha-linolenic acid (ALA) on cardiovascular homeostasis

56 hway and consequently modifies the effect of alpha-linolenic acid (ALA) on myocardial infarction (MI)

57 he control group (n = 12) received either 8% alpha-linolenic acid (ALA) or 0.6% DHA, both of which su

58 Metabolites of the alpha-linolenic acid (ALA) pathway, known to exist in pl

59 ication of four minor geometrical isomers of alpha-linolenic acid (ALA) present in linseed oil sample

60 reviously we reported that dietary intake of alpha-linolenic acid (ALA) reduces atherogenesis and inh

61 We previously reported that a diet high in alpha-linolenic acid (ALA) reduces lipid and inflammator

62 tudy is to develop vegetable oil blends with alpha-linolenic acid (ALA) rich Garden cress oil (GCO) a

63 mportance of the conversion of plant-derived alpha-linolenic acid (ALA) to EPA and DHA is debated.

64 nversion of the plant-derived n-3 fatty acid alpha-linolenic acid (ALA) to EPA and DHA is very low, n

65 Desaturation of dietary alpha-linolenic acid (ALA) to omega-3 (n-3) long-chain f

66 In a multivariable model, plasma alpha-linolenic acid (ALA) was associated with a lower r

67 n EPIC-InterAct, among long-chain n-3 PUFAs, alpha-linolenic acid (ALA) was inversely associated with

68 ng relative risks (95% CIs) for phospholipid alpha-linolenic acid (ALA) were 1.0 (reference), 0.93 (0

69 nolenic acid (GLA), and Delta(9,12,15) 18:3, alpha-linolenic acid (ALA)).

70 ega-3 FA) source, containing 1.63 g/100mL of alpha-linolenic acid (ALA), 0.73 g/100 mL of stearidonic

71 The relation between alpha-linolenic acid (ALA), a plant-derived omega-3 (n-3

72 Prior studies of alpha-linolenic acid (ALA), a plant-derived omega-3 (n-3

73 ids; palmitic acid (PA), linoleic acid (LA), alpha-linolenic acid (ALA), and oleic acid (OA), which a

74 ntagineum (EO), or rapeseed oil (RO) rich in alpha-linolenic acid (ALA), but a poor source of LC-PUFA

75 h promoting omega-3, -7, and -5 fatty acids, alpha-linolenic acid (ALA), docosahexaenoic acid (DHA),

76 with regard to any differential influence of alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA),

77 ave been made for n-3 fatty acids, including alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA),

78 about the association between adipose tissue alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA),

79 Linoleic acid (LA), alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA),

80 Circulating measures included alpha-linolenic acid (ALA), EPA, docosapentaenoic acid (

81 ipid proportions of n-3 and n-6 fatty acids [alpha-linolenic acid (ALA), EPA, docosapentaenoic acid,

82 Feeding the alga with (14)C-labeled alpha-linolenic acid (ALA), linoleic acid (LA), and olei

83 r vitamin B-12, retinol, linoleic acid (LA), alpha-linolenic acid (ALA), or ratios of betaine to chol

84 arachidonic acid to the omega3 fatty acids, alpha-linolenic acid (ALA), stearidonic acid, eicosatetr

85 n unsaturated fatty-acids, including DHA and alpha-linolenic acid (ALA), that are attached to the zwi

86 of this study was to explore whether dietary alpha-linolenic acid (ALA), the main plant omega-3, rela

87 s of the metabolic syndrome, but the role of alpha-linolenic acid (ALA), the metabolic precursor of E

88 oth LCPUFA and their precursor omega-3 PUFA, alpha-linolenic acid (ALA), whereas terrestrial insects

89 ential fatty acids (EFA), linoleic (LA), and alpha-linolenic acid (ALA).

90 ted fat (CTL) or flaxseed supplement rich in alpha-linolenic acid (ALA).

91 essential omega-3 polyunsaturated fatty acid alpha-linolenic acid (ALA).

92 essential fatty acids linoleic acid (LA) and alpha-linolenic acid (ALA); however, high-daytime temper

93 biosynthesized from n-3 FAs such as 18:3n-3 [alpha-linolenic acid (ALA)] or 20:5n-3 [eicosapentaenoic

94 f the plant-derived omega-3 (n-3) fatty acid alpha-linolenic acid (ALA, 18:3; n-3) may reduce coronar

95 Polyunsaturated fatty acids (PUFAs) such as alpha-linolenic acid (ALA, 18:3Delta(9) (cis) (,12) (cis

96 We also explored the association of alpha-linolenic acid (ALA, proxy for vegetable omega-3 i

97 (Linum usitatissimum L.) has high amounts of alpha-linolenic acid (ALA; 18:3(cis)(Delta9,12,15)) and

98 oximately 0.7% of energy), of which 1.4 g is alpha-linolenic acid (ALA; 18:3) and 0.1-0.2 g is eicosa

99 alpha-Linolenic acid (ALA; 18:3n-3) has been associated

100 We analyzed the n-3 PUFA alpha-linolenic acid (ALA; 18:3n-3); the sum of very-lon

101 ounsaturated fatty acid; MUFA), MUFA + 3.5 g alpha-linolenic acid (ALA; MUFA + ALA) from high-ALA can

102 8:2 conjugated linoleic (CLA-1.4 times), and alpha-linolenic acids (ALA-1.6 times), as compared to co

103 Plants provide alpha-linolenic acid [ALA; 18:3n-3 (18:3omega-3)], which

104 OX2(WT) displays positive cooperativity with alpha-linolenic acid (alpha-LeA, jasmonate precursor), l

105 The conversion of linoleic (LA) and alpha-linolenic acids (alpha-LNA) into these compounds m

106 rst demonstrated that linoleic acid (LA) and alpha-linolenic acid (alphaLA) induced cell death with n

107 s identified as an independent confounder of alpha-linolenic acid (an omega-3PUFA; p = 0.0210).

108 Alpha-linolenic acid, an intermediate-chain n-3 fatty ac

109 Flaxseed oil is rich in alpha-linolenic acid and bioactive compounds but highly

110 etween the ratio of dietary linoleic acid to alpha-linolenic acid and BMD at the hip in 642 men, 564

111 also reported an inverse association between alpha-linolenic acid and cardiovascular disease morbidit

112 omega-3 polyunsaturated fatty acids such as alpha-linolenic acid and docosahexaenoic acid (DHA) are

113 The omega-3 PUFAs alpha-linolenic acid and docosahexaenoic acid (DHA) inje

114 lipins from arachidonic acid, linoleic acid, alpha-linolenic acid and docosahexaenoic acid PUFAs are

115 act of P. chrysogenum afforded the compounds alpha-linolenic acid and ergosterol endoperoxide, which

116 protoporphyrin IX-reconstituted muCOX-2 with alpha-linolenic acid and G533V muCOX-2 with AA indicate

117 deficient in the essential fatty acids (EFA) alpha-linolenic acid and linoleic acid are consumed.

118 being impacted and altered in EAE, including alpha-linolenic acid and linoleic acid metabolism (PUFA)

119 ry measures to increase and decrease intakes alpha-linolenic acid and linoleic acid, respectively, to

120 Diet-tissue correlation coefficients for alpha-linolenic acid and linoleic acid, respectively, we

121 ysis products of catabolic intermediates for alpha-linolenic acid and linoleic acid, respectively.

122 L-aspartate, glutathione, prostaglandin G2, alpha-linolenic acid and linoleic acid.

123 The relationship between alpha-linolenic acid and myocardial infarction was nonli

124 n-3 alpha-linolenic acid and n-6 cis-linoleic acid were not

125 The inverse association observed between alpha-linolenic acid and nonfatal acute MI suggests that

126 mined the association between adipose tissue alpha-linolenic acid and nonfatal acute myocardial infar

127 tential source of macro- and micronutrients, alpha-linolenic acid and phytochemicals.

128 ne the association between dietary intake of alpha-linolenic acid and risk of fatal ischemic heart di

129 The specificity of the association between alpha-linolenic acid and SCD supports the hypothesis tha

130 containing 30% of 18-carbon n-3 fatty acids (alpha-linolenic acid and stearidonic acid) was developed

131 Low level of palmitic, stearic and alpha-linolenic acid and very high level of linoleic aci

132 ntaenoic acid, and docosahexaenoic acid] and alpha-linolenic acid) and n-6 PUFAs (linoleic acid and a

133 y, chia seed flour, which is rich in omega-3 alpha-linolenic acid, and common and tartary buckwheat f

134 ith significant alterations to sphingolipid, alpha-linolenic acid, and linoleic acid metabolism as we

135 and consisted of oleic acid, linoleic acid, alpha-linolenic acid, and palmitic acid.

136 f omega-3 FA, mainly due to the abundance of alpha-linolenic acid, and pre-treatment significantly im

137 bsolute amounts of dietary linoleic acid and alpha-linolenic acid are of relevance to the efficiency

138 ed the association between dietary intake of alpha-linolenic acid assessed via updated food-frequency

139 Greater alpha-linolenic acid (assessed either in adipose or by q

140 yed similar signaling properties to the LCFA alpha-linolenic acid at human FFA4 across various assay

141 ) (beta = -0.21, P = 0.060) and plant-based (alpha-linolenic acid) (beta = -0.33, P = 0.024) fatty ac

142 otential source of essential micronutrients (alpha-linolenic acid, beta-carotene, alpha-tocopherol) a

143 intake, especially docosahexaenoic acid and alpha-linolenic acid, but not omega-6 PUFA, was per stan

144 grees C, displaying a strong specificity for alpha-linolenic acid (C18:3) and regioselectivity for ca

145 urthermore, docosahexaenoic acid (C22:6n-3), alpha-linolenic acid (C18:3n-3), conjugated linoleic aci

146 is specific for linoleic acid (C18:2n-6) and alpha-linolenic acid (C18:3n-3).

147 tty acid in some vegetable oils, cis-9,12,15-alpha-linolenic acid (C18:3omega-3), administered intrav

148 yoghurt and low-fat milk always possessed an alpha-linolenic acid (C18:3omega3) content above the min

149 from 29.94 +/- 1.14% to 36.85 +/- 1.13% and alpha-linolenic acid concentrations increased from 0.78

150 s that consumption of vegetable oils rich in alpha-linolenic acid confers important protection agains

151 Encapsulation efficiency (EE) and alpha-linolenic acid content (ALA) were evaluated for al

152 roscopy data, stable-isotope data (IRMS) and alpha-linolenic acid content (gas chromatography) was us

153 of milk protein and milk fat as well as the alpha-linolenic acid content of these samples were deter

154 ontent of avocado seeds, specifically of the alpha-linolenic acid content.

155 alpha-Linolenic acid could be a viable cardioprotective

156 Consumption of vegetable oils rich in alpha-linolenic acid could confer important cardiovascul

157 acid (EPA) and docosahexaenoic acid, but not alpha-linolenic acid, decrease on a double-logarithmic s

158 The precursor n-3 PUFA alpha-linolenic acid does not appear to exert antiinflam

159 The diets were enriched in alpha-linolenic acid, eicosapentaenoic (EPA) and docosah

160 nity for the polyunsaturated n-3 fatty acids alpha-linolenic acid, eicosapentaenoic acid, docosahexae

161 Associations of n-3 PUFA biomarkers (alpha-linolenic acid, eicosapentaenoic acid, docosapenta

162 lementation of Chlorella gave rise to mainly alpha-linolenic acid enrichment.

163 fused in situ with arterial blood containing alpha-linolenic acid, EPA, or docosahexaenoic acids.

164 Oleic, linoleic and alpha-linolenic acid excretion were also significantly h

165 FGL1 was sufficient to release linoleic and alpha-linolenic acids from wheat spike tissue.

166 jects in the top quintiles of adipose tissue alpha-linolenic acid had a lower risk of MI than those i

167 s was disrupted in the tocopherol-deficient, alpha-linolenic acid-hypersensitive Synechocystis mutant

168 (95% confidence interval, 0.25 to 0.67) for alpha-linolenic acid in adipose tissue and 0.61 (95% con

169 alpha-Linolenic acid in adipose tissue ranged from 0.36%

170 The proportion of alpha-linolenic acid in CEs (P < 0.001 for group x time

171 ulted in a 90% increase in the proportion of alpha-linolenic acid in root lipids.

172 resulted in seed-specific enhanced level of alpha-linolenic acid in sesame.

173 supplements and also formed by conversion of alpha-linolenic acid in soy and rapeseed (canola) oils,

174 ions of some FAs but lower concentrations of alpha-linolenic acid in their subcutaneous adipose tissu

175 was accompanied by a continuous increase of alpha-linolenic acid in total lipids, whereas no such ac

176 ies to be more effective than its precursor, alpha-linolenic acid, in enriching membranes with eicosa

177 tricular arrhythmia, it is not known whether alpha-linolenic acid influences ventricular repolarizati

178 ompared with women in the lowest quintile of alpha-linolenic acid intake, those in the highest 2 quin

179 mega-3 fatty acids and plant omega-3 such as alpha-linolenic acid is associated with lower risk of my

180 The intake of alpha-linolenic acid is estimated to be approximately 1-

181 The apparent protective effect of alpha-linolenic acid is most evident among subjects with

182 ports the hypothesis that a higher intake of alpha-linolenic acid is protective against fatal IHD.

183 alpha-linolenic acid is the most abundant fatty acid com

184 nction with a high ratio of linoleic acid to alpha-linolenic acid, it would be prudent to recommend d

185 Plant derived alpha linolenic acid levels were not associated with inc

186 AP knockout A. thaliana plants show elevated alpha-linolenic acid levels and marked reproductive defe

187 Highest conjugated fatty acids, alpha-linolenic acid, linoleic acid, saturated fatty aci

188 (EPA) may be biosynthesized from a precursor alpha-linolenic acid (LNA) or obtained preformed in the

189 The 4-VQ addition also inhibited the alpha-linolenic acid loss.

190 Alpha-linolenic acid may protect against cardiovascular

191 ta suggest that increasing dietary intake of alpha-linolenic acid may reduce the risk of SCD but not

192 that provide polyunsaturated fats, including alpha-linolenic acid, may reduce the risk of fatal IHD.

193 y altered pathways, including the TCA cycle, alpha-linolenic acid metabolism, and valine, leucine, an

194 mption of rapeseed and flaxseed oils rich in alpha-linolenic acid (n-3).

195 n of wild-type sensitivity against exogenous alpha-linolenic acid of the otherwise resistant Deltafat

196 axseed (FS) is one of the richest sources of alpha-linolenic acid oil and lignans, and it is suggeste

197 There was increase in Omega-3 (alpha-linolenic acid), Omega-6 fatty acid (linoleic and

198 e available for evaluation of the effects of alpha-linolenic acid on serum lipid concentrations.

199 ntaenoic acid and docosahexaenoic acid or as alpha-linolenic acid) on cardiovascular disease outcomes

200 id and docosahexaenoic acid) and plant oils (alpha-linolenic acid) on human serum lipids and lipoprot

201 Here we show that the addition of alpha-linolenic acid or EPA to arterial blood inhibits t

202 -0.99] for current asthma), and the n-3 PUFA alpha-linolenic acid (OR, 0.78 [95% CI, 0.64-0.95] for a

203 Flaxseed oil is a rich source of 18:3n-3 (alpha-linolenic acid, or ALA), which is ultimately conve

204 0(palmitic acid),22:6n-3(DHA) PC > di18:3n-3(alpha-linolenic acid) PC > di22:6n-3PC with a range in p

205 rived from the enthalpy curves reflected the alpha-linolenic acid proportion in the oils.

206 rom fish or fish-oil supplements, but not of alpha-linolenic acid, reduces the rates of all-cause mor

207 d omega-3 (omega3) fatty acids (linoleic and alpha-linolenic acid, respectively) in the cytochrome P4

208 Consumption of both alpha-linolenic acid (RR, 0.73; 95% CI, 0.59-0.89; P = .

209 igh-oleic acid soybean oil (HiOleic-SO), low-alpha-linolenic acid soybean oil (LoALA-SO), or partiall

210 The fad3-2 mutant with impaired alpha-linolenic acid synthesis developed significantly s

211 presented a significantly higher content of alpha-linolenic acid than P. volubilis (51.3 and 45.6 g/

212 g., linoleic acid, spermine, spermidine, and alpha-linolenic acid) that may regulate the early develo

213 g reduced omega6:omega3 ratio and heightened alpha-linolenic acid through sunflower (SO): linseed oil

214 the essential fatty acids linoleic acid and alpha-linolenic acid to arachidonic acid and DHA, respec

215 relevance to the efficiency of conversion of alpha-linolenic acid to eicosapentaenoic acid and docosa

216 The previously recognized capability of alpha-linolenic acid to stimulate the generation of adip

217 ignificantly increased the concentrations of alpha-linolenic acid, total polyunsaturated fatty acids

218 PUFA dihomo-gamma-linolenic acid; gamma- and alpha-linolenic acids, two popular dietary PUFAs, were l

219 LA uptake and [3H]thymidine incorporation by alpha-linolenic acid was 0.18 and 0.25 mM, respectively.

220 acid and other nutrients, a higher intake of alpha-linolenic acid was associated with a lower relativ

221 Dietary intake of alpha-linolenic acid was associated with an increased ri

222 alpha-Linolenic acid was associated with moderately incr

223 The intake of alpha-linolenic acid was derived from a 116-item food-fr

224 In comparison, plant-derived alpha-linolenic acid was inversely associated with morta

225 ng long-chain n-3 fatty acids, the intake of alpha-linolenic acid was inversely associated with the r

226 cosahexaenoic acid + docosapentaenoic acid + alpha-linolenic acid) was associated with lower ventricu

227 Use of mustard oil, which is rich in alpha-linolenic acid, was associated with a lower risk t

228 negar salad dressing, an important source of alpha-linolenic acid, was associated with reduced risk o

229 wk of treatment, plasma phospholipid EPA and alpha-linolenic acid were greater in children consuming

230 el of stearic, palmitic, oleic, linoleic and alpha-linolenic acids were slightly changed and FTIR spe

231 Dietary omega-3 fatty acids (eg, alpha-linolenic acid) were inhibitory at concentrations

232 ted fatty acids (rich in oleic, linoleic and alpha-linolenic acids) were supplemented to dairy ewes a

233 om polyunsaturated fatty acids (linoleic and alpha-linolenic acid), whereas for "Vatikiotiko" saturat

234 were highly resistant to externally provided alpha-linolenic acid, whereas wild-type cells bleached u

235 site and is highly active with linoleic and alpha-linolenic acids (which occur naturally in Anabaena

236 turated free fatty acids (FFAs) linoleic and alpha-linolenic acid, which we detected in F. graminearu

237 Specifically, the miR167OE seeds had a lower alpha-linolenic acid with a concomitantly higher linolei

238 also observed when adding the JA precursor, alpha-linolenic acid with SA.

239 acid, docohexaenoic acid, linoleic acid, and alpha-linolenic acid, with incident CVD and all-cause mo