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1  role in modulating the adhesive function of alpha4beta1 integrin.
2 that anti-SG1 IgG prevents ligand binding by alpha4beta1 integrin.
3  memory cells and triggers activation of the alpha4beta1 integrin.
4  potential, that also express high levels of alpha4beta1 integrin.
5 X9, but not GST, and binding was mediated by alpha4beta1 integrin.
6 ntial activities to inhibit human and murine alpha4beta1 integrin.
7 spreading and stress fiber formation through alpha4beta1 integrin.
8 with lamin B1 during T-cell adhesion through alpha4beta1 integrin.
9 (LFA-1) is known to induce cross-talk to the alpha4beta1 integrin.
10 g trafficking receptors and instead required alpha4beta1-integrin.
11 hesiveness, due in part to the activation of alpha4beta1 integrins.
12 xpress alpha(v)beta5, beta2, alpha2beta1, or alpha4beta1 integrins.
13 g pathway also suppressed sVCAM-1 binding to alpha4beta1 integrins.
14                                              alpha4beta1 integrin activation did not depend on pertus
15 ce triggers actin polymerization at upstream alpha4beta1 integrin adhesion sites and the adjacent cor
16 ent on B-Raf activity or expression, whereas alpha4beta1 integrin affinity for soluble VCAM-1 was not
17 that the gene encoding the alpha4 subunit of alpha4beta1 integrin (alpha4beta1) is essential for this
18 es directed against the alpha-subunit of the alpha4beta1 integrin and against intracellular cell adhe
19 d by the presence of extradomain A activates alpha4beta1 integrin and augments osteoblast differentia
20 ly selective and functional link between the alpha4beta1 integrin and IL-3/IL-3-receptor that could a
21  These effects were shown to be specific for alpha4beta1 integrin and not other integrins, such as al
22 equence in blade B4 (P3 sequence) that bound alpha4beta1 integrin and partially impaired cell adhesio
23 expression was coordinately regulated by the alpha4beta1 integrin and the innate immune receptor toll
24  cell-stromal cell interactions mediated via alpha4beta1 integrin and vascular cell adhesion molecule
25 co-signaling pathway between alpha5beta1 and alpha4beta1 integrins and are independent of heparan sul
26 mily, supports leukocyte adhesion by binding alpha4beta1 integrins and is critical for the recruitmen
27 n antagonistic, role between alpha5beta1 and alpha4beta1 integrins and suggests that interactions bet
28 ndent manner via very late antigen-4 (VLA-4; alpha4beta1 integrins) and VLA-5 (alpha5beta1 integrins)
29 by alphavbeta3, alphavbeta5, alpha5beta1, or alpha4beta1 integrin, and antagonists for the integrins
30 hocyte function-associated antigen (LFA)-1], alpha4beta1 integrin, and cadherin-11 in the development
31  T cells depended on the activation state of alpha4beta1 integrin, and TSP1 inhibited interaction of
32 ted from MOLT-4 T leukemia cells, using anti-alpha4beta1 integrin antibody-coated beads.
33 adhesion molecule-1 (VCAM-1) and its ligand, alpha4beta1 integrin, are key mediators of leukocyte rec
34  is not related to surface expression of the alpha4beta1 integrin, as demonstrated by flow cytometry.
35  and stress fiber formation were mediated by alpha4beta1 integrin because soluble anti-alpha4 integri
36 agment of fibronectin, which contains a weak alpha4beta1 integrin binding sequence.
37 ragment of fibronectin, which contains three alpha4beta1-integrin binding sites, or the H0 fragment,
38 of fibronectin, which contains the strongest alpha4beta1 integrin-binding sequence.
39   In the current study, we demonstrated that alpha4beta1 integrin binds to CSGAG.
40                                Low levels of alpha4beta1 integrin can be detected on neutrophils from
41          The avidity of the cells expressing alpha4beta1 integrin can be rapidly changed by chemokine
42 egulate chemotaxis-related proteins, such as alpha4beta1 integrin, CCL7, CCL8, and CXCL16.
43                  Very-late-antigen-4 (VLA-4, alpha4beta1 integrin, CD49d/CD29) is a transmembrane adh
44 eukotriene B4 signaling and induction of the alpha4beta1 integrin cell adhesion complex in hematopoie
45 t interactions between the Hep II domain and alpha4beta1 integrin could modulate the strength of cyto
46 TSP2 containing this sequence replicated the alpha4beta1 integrin-dependent activities of TSP1.
47 marked defect in alphavbeta3/alphavbeta5 and alpha4beta1 integrin-directed migration measured on vitr
48 emonstrate that T-cell adhesion to VCAM1 via alpha4beta1 integrin drives histone H3 methylation (H3K9
49 at two such molecules, E-selectin ligand and alpha4beta1 integrin, enable activated and memory T cell
50                                Specifically, alpha4beta1 integrin engagement rescues B cells from phy
51               Stimulation of T cells via the alpha4beta1 integrin enhances the association of tyrosin
52    Activated T cells use very late antigen-4/alpha4beta1 integrin for capture, rolling on, and firm a
53 tion of 50% = 2 pM) that binds the activated alpha4beta1 integrin found on a variety of malignant lym
54                We examined the regulation of alpha4beta1 integrin function in melanoma cells and T ce
55                  We examined the function of alpha4beta1 integrin in angiogenesis and in mediating en
56 studies have suggested an important role for alpha4beta1 integrin in this process.
57 s migration of fibroblast-like cells lacking alpha4beta1 integrin, in which Rac1 and myosin II modula
58                  This process is mediated by alpha4beta1 integrin, indicating that integrin triggerin
59 c lung fibroblasts, we show that ligation of alpha4beta1 integrin induces a significant increase in p
60                     In contrast, ligation of alpha4beta1 integrin inhibits basement membrane invasion
61 B3B4, we have identified B3B4 as the primary alpha4beta1 integrin-interacting region within PEX9.
62               We examined the role of VCAM-1/alpha4beta1 integrin interaction in T cell recruitment t
63           These results indicate that VCAM-1/alpha4beta1 integrin interaction is crucial for prompt r
64           Our data also suggest that the EDA/alpha4beta1 integrin interaction primes the cell for an
65  novel aspect of the function of fibronectin-alpha4beta1 integrin interactions that holds significanc
66        Moreover, the blockade of fibronectin-alpha4beta1-integrin interactions inhibited the expressi
67               These results demonstrate that alpha4beta1 integrin interacts directly with CSGAG throu
68 nt-1 (CS-1) peptide therapy, which blocks FN-alpha4beta1 integrin leukocyte interactions, in a well-e
69 nan but had no effect on adhesion to VCAM-1 (alpha4beta1 integrin ligand), confirming its specific in
70 1) as a model LDV-containing ligand to study alpha4beta1 integrin-ligand interactions on Jurkat cells
71 reduces T cell resistance to shear stress to alpha4beta1 integrin ligands vascular cell adhesion mole
72  that aberrantly coexpressed alpha4beta7 and alpha4beta1 integrins, markedly decreasing local product
73                    We now show that moncytic alpha4beta1 integrins mediate binding to MM-LDL-treated
74 er by studying the role of growth factors on alpha4beta1 integrin-mediated adhesion of human CD34+ he
75 receptors supported robust agonist-dependent alpha4beta1 integrin-mediated adhesion of lymphocytes to
76 motility mediated by CXCR4 and CXCL12 and by alpha4beta1 integrin-mediated adhesion to VCAM-1.
77 ole for B-Raf in the selective regulation of alpha4beta1 integrin-mediated adhesion.
78                    Such cross talk decreases alpha4beta1 integrin-mediated binding of T cells to fibr
79 ect genetic evidence for essential roles for alpha4beta1 integrin-mediated cell adhesion in the migra
80                         Soluble SG1 inhibits alpha4beta1 integrin-mediated human melanoma cell adhesi
81  type I PKA is important for localization of alpha4beta1 integrin-mediated PKA activation at the lead
82                                   We studied alpha4beta1 integrin-mediated signaling, which regulates
83    We have examined the relationship between alpha4beta1-integrin-mediated adhesion and growth of CD3
84 revealed co-localization between FXIII-A and alpha4beta1 integrins, more prominently for Lys679Met FX
85 ing segment-1 (CS1)-binding domain of FN and alpha4beta1 integrin on circulating cells may interfere
86 ing segment-1 (CS1)-binding domain of FN and alpha4beta1 integrin on circulating cells may prevent th
87 ic db/db ECs was mediated by interactions of alpha4beta1 integrin on monocytes with endothelial vascu
88                            The expression of alpha4beta1 integrin on peripheral blood CD4(+) T cells
89         These studies therefore identify the alpha4beta1 integrin on SS RBCs as a CD47-activated rece
90 esent evidence that interactions between the alpha4beta1 integrin on sympathetic neurons and vascular
91  and TSP1 inhibited interaction of activated alpha4beta1 integrin on T cells with its counter recepto
92                     Instead, newly activated alpha4beta1 integrins organize on the cell membrane as i
93                                              alpha4beta1 integrin plays an important role in cell mig
94                                 We show that alpha4beta1 integrin promotes cell migration through bot
95 del in which in vivo interaction between the alpha4beta1 integrin receptor and the cell-associated CS
96                                          The alpha4beta1 integrin recognition site is conserved in TS
97 the spatiotemporal organization of activated alpha4beta1 integrins regulates T lymphocyte adhesion.
98 alpha4beta7 integrin, E-selectin ligand, and alpha4beta1 integrin, respectively.
99 entify a novel mechanism in T-cells by which alpha4beta1 integrin signaling drives specific chromatin
100  study suggests that cooperative alpha5beta1/alpha4beta1 integrin signaling may be regulated by ILK t
101 iated HTM cells could be rescued by inducing alpha4beta1 integrin signaling with a recombinant Hep II
102 nectin were used to activate alpha5beta1 and alpha4beta1 integrin signaling, respectively, in differe
103                          We report here that alpha4beta1 integrin stimulation of H9 T cells and norma
104 1, and most displayed enhanced levels of the alpha4beta1 integrin that interacts with VCAM-1.
105 dition to its recognition by alpha3beta1 and alpha4beta1 integrins, the N-terminal pentraxin module o
106 failure of PC/pvSMCs, which normally express alpha4beta1 integrin, to spread uniformly along the vess
107            This high level of involvement of alpha4beta1 integrin/VCAM-1 is unique among secondary ly
108 ion cascade, which includes L-selectin/PNAd, alpha4beta1 integrin/VCAM-1, and LFA-1, targets specific
109 transmigration of this subset depends on the alpha4beta1 integrin very late antigen (VLA)-4.
110                 Here we demonstrate that the alpha4beta1 integrin (VLA-4) is the receptor that mediat
111         Fibronectin binding was mediated via alpha4beta1 integrin (VLA-4), which is expressed at high
112 e-mediated induction of adhesion between the alpha4beta1 integrin, VLA-4, and VCAM-1.
113 nt Hep II domain of fibronectin, even though alpha4beta1 integrins were not found in FAs.
114 endothelial cells through the interaction of alpha4beta1 integrin with endothelial Lutheran/basal cel
115                           The association of alpha4beta1 integrin with the actin cytoskeleton was sho
116          Here, we show targeting alpha9beta1/alpha4beta1 integrins with a single dose of a small mole

 
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