ライフサイエンスコーパス: alphaherpesvirus

1 a-zoster virus (VZV) are conserved among all alphaherpesvirus.

2 ssociated, and exclusively human neurotropic alphaherpesvirus.

3 aricella-zoster virus (VZV) is a neurotropic alphaherpesvirus.

4 been seen with any other previously examined alphaherpesvirus.

5 n Marek's disease virus (MDV), a tumorigenic alphaherpesvirus.

6 is the first reported Bcl-2 homologue in an alphaherpesvirus.

7 the gD gene, MDV is an intermediate type of alphaherpesvirus.

8 embrane protein UL20 are conserved among all alphaherpesviruses.

9 e for the largest herpesvirus subfamily, the alphaherpesviruses.

10 the host immune responses to closely related alphaherpesviruses.

11 protein, referred to as VP26 (UL35) in other alphaherpesviruses.

12 ent proteins and is highly conserved in most alphaherpesviruses.

13 nteraction that is, so far, unique among the alphaherpesviruses.

14 tegument proteins and is conserved among the alphaherpesviruses.

15 ional analysis of this unique class of avian alphaherpesviruses.

16 volutionarily in HSV-1 and other neurotropic alphaherpesviruses.

17 n 1) have been shown to mediate the entry of alphaherpesviruses.

18 on the anti-chemokine strategies encoded by alphaherpesviruses.

19 ting that the interaction is conserved among alphaherpesviruses.

20 verall genome organization characteristic of alphaherpesviruses.

21 rences from their structural counterparts in alphaherpesviruses.

22 otein B revealed that LETV clusters with the alphaherpesviruses.

23 stics and also features in common with other alphaherpesviruses.

24 oded by the UL49 gene is conserved among the alphaherpesviruses.

25 UL49 homologs are conserved among alphaherpesviruses.

26 The Us9 gene is conserved among most alphaherpesviruses.

27 and may not apply to VP22 homologs of other alphaherpesviruses.

28 t for maintaining these functions across all alphaherpesviruses.

29 gs revealed that Y480 was conserved only for alphaherpesviruses.

30 ino terminus of gK, which is conserved among alphaherpesviruses.

31 serve similar conserved functions for other alphaherpesviruses.

32 Bovine alphaherpesvirus 1 (BoHV-1) is an important pathogen of

33 ce of CDK5 inhibitory peptide (CIP) on Human alphaherpesvirus 1 (HSV-1) replication, we constructed t

34 ek's disease in chickens is caused by Gallid alphaherpesvirus 2, better known as Marek's disease alph

35 T cell reactivity to the noncausative human alphaherpesvirus (alphaHHV) is commonly detected in the

36 Other alphaherpesviruses also express ICP0-related RING finger

37 elated RING finger proteins encoded by other alphaherpesviruses also induce colocalizing, conjugated

38 ent structural similarities between KSHV and alphaherpesvirus, an ORF19 monomer in KSHV, in contrast

39 ice with another picornavirus, as well as an alphaherpesvirus and a rhabdovirus.

40 ly 4 (IE4) protein, which is conserved among alphaherpesvirus and has transactivation activity in tra

41 la-zoster virus (VZV) is a human neurotropic alphaherpesvirus and the etiological agent of varicella

42 virus (PRV) Us3 gene is conserved among the alphaherpesviruses and encodes a serine/threonine protei

43 by ICP0-related proteins expressed by other alphaherpesviruses and even by a combination of the unre

44 21 is a conserved protein in the tegument of alphaherpesviruses and has multiple important albeit poo

45 Homologs of U(L)3.5 are present in some alphaherpesviruses and have 20 to 30% overall amino acid

46 similar to that which has been proposed for alphaherpesviruses and involve envelopment of tegumented

47 are conserved with the ICP4 analogs of other alphaherpesviruses and were also predicted to be exposed

48 Infection with gammaherpesviruses, alphaherpesviruses, and betacoronaviruses can result in

49 ns, gE, gI, and Us9, have been implicated in alphaherpesvirus anterograde spread in several animal mo

50 Alphaherpesviruses are a subfamily of herpesviruses that

51 of viral intracellular transport.IMPORTANCE Alphaherpesviruses are among the very few viruses that a

52 gI, respectively), Us9 and its homologue in alphaherpesviruses are necessary for the viral anterogra

53 Alphaherpesviruses are neuroinvasive pathogens that esta

54 Alphaherpesviruses are parasites of the peripheral nervo

55 ve produced contradictory conclusions on how alphaherpesviruses are transported from neuron cell bodi

56 e of virus following reactivation.IMPORTANCE Alphaherpesviruses are ubiquitous DNA viruses and includ

57 Herpes simplex virus (HSV) and other alphaherpesviruses assemble enveloped virions in the tra

58 IMPORTANCE Marek's disease virus (MDV) is an alphaherpesvirus associated with Marek's disease (MD), a

59 In turn, alphaherpesviruses benefit from this partial loss-of-bar

60 hin members of one of the three subfamilies (alphaherpesviruses, betaherpesviruses, or gammaherpesvir

61 Like other alphaherpesviruses, BHV-1 establishes latency in sensory

62 omer in KSHV, in contrast to a UL25 dimer in alphaherpesviruses, binds each penton subunit, an observ

63 gument proteins is highly similar to that in alphaherpesvirus but completely different from that in b

64 vertex, a pattern highly similar to that in alphaherpesvirus but completely different from that in b

65 irus (EBV) differs not only from that of the alphaherpesviruses but also from that of the gamma-2 her

66 o that of HSV-1 and other neurotropic animal alphaherpesviruses but differs from that reported for VZ

67 The Us2 gene is conserved among alphaherpesviruses, but its function is not known.

68 syn loci.IMPORTANCE UL21 is conserved among alphaherpesviruses, but its role is poorly understood.

69 , was shown not to be conserved in the other alphaherpesviruses by bioinformatics analysis.

70 ings question the longstanding paradigm that alphaherpesviruses can establish spontaneous latency onl

71 Using pseudorabies virus (PRV), an alphaherpesvirus capable of transneuronal spread in neur

72 How alphaherpesvirus capsids acquire tegument proteins remai

73 Upon entering a cell, alphaherpesvirus capsids are transported toward the minu

74 ll structural similarities of RRV capsids to alphaherpesvirus capsids suggest a common assembly and m

75 "naked" and membrane-associated cytoplasmic alphaherpesvirus capsids.

76 -mediated trafficking of naked and enveloped alphaherpesvirus capsids.

77 Marek's disease virus (MDV), an avian alphaherpesvirus, causes a deadly lymphoma in chickens a

78 Varicella-zoster virus (VZV), a neurotropic alphaherpesvirus, causes childhood chickenpox (varicella

79 Marek's disease virus (MDV), a lymphotropic alphaherpesvirus, causes Marek's disease (MD) in chicken

80 Pseudorabies virus (PRV), a broad host range alphaherpesvirus, causes violent pruritus in many differ

81 alled human herpesvirus 3 [HHV3]), the human alphaherpesvirus causing varicella and herpes zoster, ex

82 nal half of UL37 from pseudorabies virus, an alphaherpesvirus closely related to herpes simplex virus

83 functionally characterize intraocular human alphaherpesvirus cross-reactive T cells.

84 Attenuated alphaherpesvirus derivatives have been used extensively

85 tant for identifying novel targets to reduce alphaherpesvirus disease.

86 As with other alphaherpesviruses, efficient EHV-1 entry was dependent

87 HVT079 and HVT096 genes, is the first known alphaherpesvirus-encoded Bcl-2 homolog.

88 om the study of several LAT mutants of other alphaherpesviruses encoding miRNAs from their LAT region

89 y analysis to determine if these two diverse alphaherpesviruses engage similar or different cellular

90 en though these cells do not express a known alphaherpesvirus entry receptor.

91 eins function with the previously identified alphaherpesvirus entry receptors nectin-1 and CD155 but

92 he murine cDNA in hamster cells resistant to alphaherpesvirus entry, the cells became susceptible to

93 ill contribute to a broader understanding of alphaherpesvirus entry.

94 The alphaherpesvirus envelope protein Us9 is a type II viral

95 -type mice, CCL3(-/-) mice infected with the alphaherpesvirus equine herpesvirus 1 (EHV-1) displayed

96 Our findings showed that the alphaherpesvirus equine herpesvirus 1 (EHV-1) efficientl

97 ntified as a cellular entry receptor for the alphaherpesvirus equine herpesvirus type 1 (EHV-1).

98 We used the alphaherpesvirus equine herpesvirus type 1 (EHV1) and eq

99 infection by the host-specific and ancestral alphaherpesvirus equine herpesvirus type 1 (EHV1).

100 We demonstrate how a central alphaherpesvirus, equine herpesvirus type 1 (EHV1), actu

101 Many alphaherpesviruses establish a latent infection in the p

102 These data identify an alphaherpesvirus evasion strategy from NK cells and poin

103 Two models describing how alphaherpesviruses exit neurons differ with respect to w

104 Alphaherpesviruses express a heterodimeric glycoprotein,

105 us type 1 (EHV1), a well-known member of the alphaherpesvirus family, was used to infect equine respi

106 s 1 (SaHV-1) genome, a primate member of the alphaherpesvirus family.

107 of ICP0 are encoded by other members of the alphaherpesvirus family.

108 In the case of alphaherpesviruses, few reports have focused on those as

109 beta-sheet domain, which is conserved among alphaherpesviruses, functions in HSV-1 entry into neuron

110 Alphaherpesvirus gC proteins are type 1 membrane protein

111 cell fusion along with gL, gB, and, in most alphaherpesviruses, gD.

112 ing both murine nectin-1alpha and one of the alphaherpesvirus gDs were resistant to entry of HSV-1, i

113 In contrast to other alphaherpesviruses, gE is essential for VZV replication.

114 lacked an endocytosis motif, while all other alphaherpesvirus gH homologues contained a potential mot

115 In alphaherpesviruses, glycoprotein B (gB), gD, gH, and gL

116 Glycoprotein G (gG) of alphaherpesviruses has been described to function as a v

117 t functions that may have some redundancy in alphaherpesviruses have been concentrated in fewer prote

118 These results indicate that these alphaherpesviruses have differing preferences for entry

119 ated receptor in the respiratory epithelium, alphaherpesviruses have generated a strategy to efficien

120 The alphaherpesviruses have long been considered vectors for

121 e important to the ability of the prototypic alphaherpesvirus herpes simplex virus 1 (HSV-1) to enter

122 Entry of the human alphaherpesvirus herpes simplex virus 1 (HSV-1) was inde

123 svirus (KSHV) and the more distantly related alphaherpesvirus herpes simplex virus 1 (HSV-1).

124 MDV1 is colinear with the prototypic alphaherpesvirus herpes simplex virus type 1 (HSV-1) wit

125 productive replication of the representative alphaherpesvirus herpes simplex virus type 1, the repres

126 ression of immediate-early (IE) genes of the alphaherpesviruses herpes simplex virus type 1 (HSV-1) a

127 pression of the immediate-early genes of the alphaherpesviruses herpes simplex virus type 1 and varic

128 Studies of UL37 homologs from two alphaherpesviruses, herpes simplex virus 1 (HSV-1) and p

129 ously demonstrated that gB homologs from two alphaherpesviruses, herpes simplex virus 1 (HSV-1) and s

130 anglia latently infected with two pathogenic alphaherpesviruses, herpes simplex virus 1 (HSV-1) and v

131 The distribution of the neurotropic alphaherpesviruses-herpes simplex virus type 1 (HSV-1) a

132 U(S)3 have been extensively studied in other alphaherpesviruses; however, the biological functions of

133 By swapping the entry glycoproteins of two alphaherpesviruses (HSV-1 and SaHV-1), we previously dem

134 pesvirus, KSHV, and a more distantly related alphaherpesvirus, HSV-1.

135 lar to those in HSV-1 are conserved in other alphaherpesviruses, (iii) CTCF binds to these motifs on

136 estimated 99 putative proteins and resembles alphaherpesviruses in genomic organization and gene cont

137 n comparisons of the pathogenicity of simian alphaherpesviruses in mice, two isolates of the baboon v

138 The alphaherpesviruses include several important human patho

139 Other alphaherpesviruses, including herpes simplex virus (HSV)

140 and those induced by other, closely related alphaherpesviruses, including HSV-1 and -2.

141 The various alphaherpesviruses, including Marek's disease virus (MDV

142 Alphaherpesviruses, including pseudorabies virus (PRV),

143 Alphaherpesviruses, including pseudorabies virus (PRV),

144 During infection of the nervous system, alphaherpesviruses-including pseudorabies virus (PRV)-us

145 well understood, although analyses of other alphaherpesviruses indicate a role for chromatin in viru

146 Transport of capsids in cells is critical to alphaherpesvirus infection and pathogenesis; however, vi

147 To date, the polarity of alphaherpesvirus infection in the respiratory epithelium

148 An essential process for alphaherpesvirus infection is spread from axons of perip

149 Alphaherpesvirus infection of the mammalian nervous syst

150 motility and morphology are disrupted during alphaherpesvirus infection, which aids viral replication

151 ional response of the mammalian CNS to acute alphaherpesvirus infection.

152 of altered mitochondrial dynamics following alphaherpesvirus infections and identify a key determina

153 A clinical hallmark of human alphaherpesvirus infections is peripheral pain or itchin

154 ble for long-distance, directional spread of alphaherpesvirus infections via axons of infected neuron

155 in the host's innate defence against primary alphaherpesvirus infections.

156 f the craniofacial nervous system and latent alphaherpesvirus infections.

157 The structure--the first for any alphaherpesvirus inner tegument protein--reveals an elon

158 The neurotropic alphaherpesviruses invade and spread in the nervous syst

159 U(S)3 encoded by alphaherpesviruses is a multifunctional kinase involved

160 ycle of herpes simplex virus (HSV) and other alphaherpesviruses is the capacity to reactivate from la

161 A defining characteristic of alphaherpesviruses is the establishment of lifelong late

162 la-zoster virus (VZV), a double-stranded DNA alphaherpesvirus, is associated with seasonal outbreaks

163 Marek's disease virus (MDV), an alphaherpesvirus, is the causative agent of a lethal dis

164 erpes simplex virus 1 (HSV-1), the prototype alphaherpesvirus, is ubiquitous in the human population

165 Glycoprotein K (gK), conserved in all alphaherpesviruses, is a multi-membrane spanning virion

166 VZV IE62, which is well conserved within the alphaherpesviruses, is needed for trans-activation media

167 he first time these have been reported in an alphaherpesvirus), (iv) a sizeable region of the genome

168 M complex is more striking than that of most alphaherpesviruses lacking the same complex but resemble

169 molecular mechanisms of pain associated with alphaherpesvirus latency are not clear.

170 Yet alphaherpesvirus latency in TSG has not been well charac

171 iated transcript (LAT) gene is a hallmark of alphaherpesvirus latency, and yet its control and functi

172 xon terminus) is a critical component of the alphaherpesvirus life cycle.

173 tus/trans-Golgi network as a platform in the alphaherpesvirus life cycle.

174 n binding protein (OBP) proteins and have an alphaherpesvirus-like dyad symmetry Ori-Lyt domain.

175 t proteins from pseudorabies virus (PRV), an alphaherpesvirus, localize to mitochondria and affect mi

176 this protease is still unclear, but for the alphaherpesvirus Marek's disease virus, its USP is invol

177 erative disease of chickens, is caused by an alphaherpesvirus, Marek's disease virus (MDV).

178 's disease (MD) in chickens is caused by the alphaherpesvirus MD virus (MDV) and is characterized by

179 tural animal model system of Marek's disease alphaherpesvirus (MDV) in chickens, CHPK is absolutely r

180 eins are dysregulated during Marek's disease alphaherpesvirus (MDV) replication in cell culture.

181 rpesvirus 2, better known as Marek's disease alphaherpesvirus (MDV).

182 cts the poultry industry and is caused by MD alphaherpesvirus (MDV).

183 the subfamily Alphaherpesvirinae Like other alphaherpesviruses, MDV encodes a serine/threonine prote

184 Alphaherpesvirus-mediated membrane fusion is a complex a

185 reater understanding of mechanisms governing alphaherpesvirus membrane fusion is expected to inform t

186 uenced, demonstrating that this virus was an alphaherpesvirus most closely related to the gallid herp

187 Herpes simplex virus (HSV) and other alphaherpesviruses must move from sites of latency in ga

188 in-2 to test the effects on entry of various alphaherpesviruses, nectin-nectin interactions, and inte

189 Mammalian alphaherpesviruses normally establish latent infections

190 if Marek's disease virus (MDV), an oncogenic alphaherpesvirus of chickens, encodes miRNAs, we isolate

191 virus (MDV), a highly contagious and deadly alphaherpesvirus of chickens, we analyze the role of teg

192 imian varicella virus (SVV) is a neurotropic alphaherpesvirus of monkeys that is a model for varicell

193 pesvirus of turkeys (HVT) is a nonpathogenic alphaherpesvirus of turkeys and chickens that is widely

194 HCMV; it has no activity against other CMVs, alphaherpesviruses, or unrelated viruses.

195 -6A and -6B), HHV-7 encodes a homolog of the alphaherpesvirus origin binding protein (OBP), which bin

196 humans and animals is frequently exposed to alphaherpesviruses, originating from either external exp

197 ng reports regarding the importance of gK to alphaherpesvirus pathogenesis and details important stru

198 hat altered mitochondrial transport enhances alphaherpesvirus pathogenesis and infection.

199 issues to decipher this key event in general alphaherpesvirus pathogenesis.

200 Neurotropism is a defining characteristic of alphaherpesvirus pathogenicity.

201 UL20, which are highly conserved across all alphaherpesviruses, play important roles in the regulati

202 to captive primates, who reciprocally harbor alphaherpesviruses poised for zoonotic transmission to h

203 uitinase-encoding domain was dispensable for alphaherpesvirus propagation, but the rate of propagatio

204 rst report to describe the prenylation of an alphaherpesvirus protein.

205 The alphaherpesvirus PrV is known for its neuroinvasion, whe

206 The alphaherpesvirus pseudorabies virus (PrV) establishes la

207 The alphaherpesvirus pseudorabies virus (PRV) is the causati

208 Interestingly, entry of the porcine alphaherpesvirus pseudorabies virus (PRV) was inhibited

209 extend these studies, we compared gH of the alphaherpesvirus pseudorabies virus (PrV) with gH of the

210 Using an infectious clone of the alphaherpesvirus pseudorabies virus, we have made a coll

211 e, we report that the gD glycoprotein of the alphaherpesviruses pseudorabies virus (PRV) and herpes s

212 the BoHV-1 entry pathway with those of other alphaherpesviruses (pseudorabies virus [PRV] and herpes

213 contrast to a similar mutant of the related alphaherpesvirus, pseudorabies virus, and suggests that

214 and differences between HSV1 and the related alphaherpesvirus, pseudorabies virus, in which the homol

215 Alphaherpesvirus reactivation from thoracic sympathetic

216 Pseudorabies virus (PRV), an alphaherpesvirus related to herpes simplex virus type 1

217 ns.IMPORTANCE Pseudorabies virus (PRV) is an alphaherpesvirus related to human pathogens herpes simpl

218 Pseudorabies virus (PRV) is an alphaherpesvirus related to the human pathogens herpes s

219 Following reactivation from latency, alphaherpesviruses replicate in sensory neurons and asse

220 Thus, alphaherpesviruses repurpose the axonal transport and so

221 virus (VZV), a ubiquitous human neurotropic alphaherpesvirus, requires coordinated binding of multip

222 sequence of bovine herpesvirus 5 (BHV-5), an alphaherpesvirus responsible for fatal meningoencephalit

223 Varicella-zoster virus (VZV), an alphaherpesvirus restricted to humans, infects different

224 eral deletions in regions conserved in other alphaherpesviruses resulted in impaired activation and v

225 varicella-zoster virus (VZV), a neurotropic alphaherpesvirus, results in varicella.

226 Alignment of UL37 homologs encoded by alphaherpesviruses revealed the presence of highly conse

227 t E454 is invariant in a number of different alphaherpesvirus scaffold proteins.

228 No recombinant alphaherpesvirus serine kinase has been biologically act

229 t UL37 tyrosine residues conserved among all alphaherpesviruses serve critical roles in cytoplasmic v

230 The Vhs homologues of alphaherpesviruses share sequence similarities with a fa

231 erpesvirus therapeutic strategies across all alphaherpesvirus species that would be absent from more

232 Moreover, it identifies the alphaherpesvirus-specific Us3 kinase as an mTORC1 activa

233 Alphaherpesviruses spread rapidly through dermal tissues

234 ort to determine the function of a conserved alphaherpesvirus structural protein called Us2, we scree

235 Characteristic of members of the alphaherpesvirus subfamily, VZV is neurotropic and estab

236 Like HSV-1, SaHV-1 belongs to the alphaherpesvirus subfamily.

237 lated simian simplexviruses belonging to the alphaherpesvirus subfamily.

238 highly conserved among other members of the alphaherpesvirus subfamily.

239 ), which is conserved in most viruses of the alphaherpesvirus subfamily.

240 After replicating in epithelial cells, alphaherpesviruses such as pseudorabies virus (PRV) inva

241 associated and has a lower titer than other alphaherpesviruses, such as herpes simplex virus 1 (HSV1

242 is especially important in the neuroinvasive alphaherpesviruses, such as human herpes simplex virus 1

243 ORTANCE Herpes simplex virus (HSV) and other alphaherpesviruses, such as varicella-zoster virus, depe

244 by sequence alignment to be conserved among alphaherpesviruses, suggesting a functional role.

245 protein kinase found in the short region of alphaherpesviruses, termed US3 in herpes simplex virus t

246 Varicella-zoster virus (VZV) is the alphaherpesvirus that causes chicken pox (varicella) and

247 aricella zoster virus (VZV) is a neurotropic alphaherpesvirus that causes chickenpox during primary i

248 Marek's disease virus (MDV) is an alphaherpesvirus that causes deadly T-cell lymphomas in

249 Bovine herpesvirus 1 (BoHV-1) is an alphaherpesvirus that causes disease in cattle populatio

250 virus (MDV) is a highly contagious oncogenic alphaherpesvirus that causes disease that is both a canc

251 ine herpesvirus 5 (BHV-5) is a neurovirulent alphaherpesvirus that causes fatal encephalitis in calve

252 disease virus (MDV) is an acute transforming alphaherpesvirus that causes T-cell lymphomas in chicken

253 Varicella-zoster virus (VZV) is an alphaherpesvirus that causes two diseases, chickenpox an

254 Varicella-zoster virus (VZV) is an alphaherpesvirus that causes varicella and herpes zoster

255 Varicella-zoster virus (VZV) is an alphaherpesvirus that causes varicella upon primary infe

256 Varicella-zoster virus (VZV) is a human alphaherpesvirus that infects sensory ganglia and reacti

257 Varicella-zoster virus (VZV) is an alphaherpesvirus that infects skin, lymphocytes, and sen

258 Varicella-zoster virus (VZV) is a human alphaherpesvirus that is highly cell associated in cell

259 Equine herpesvirus 1 (EHV1) is an ancestral alphaherpesvirus that is related to herpes simplex virus

260 Varicella-zoster virus (VZV) is an alphaherpesvirus that is restricted to humans.

261 report that varicella-zoster virus (VZV), an alphaherpesvirus that is the causative agent of varicell

262 opithecine herpesvirus 1) is the only deadly alphaherpesvirus that is zoonotically transmissible from

263 Varicella-zoster virus (VZV) is an alphaherpesvirus that lacks the herpesviral neurovirulen

264 represent a phylogenetically unique clade of alphaherpesviruses that are distinct from the Marek's di

265 cella-zoster virus (VZV) are closely related alphaherpesviruses that cause varicella (chickenpox) in

266 K) is a conserved virion glycoprotein of all alphaherpesviruses that is not found in other herpesviru

267 out a possible pathogenic branch of cetacean alphaherpesviruses that might be responsible for some fa

268 In alphaherpesviruses, the alpha-subunit (VP19c in HSV) has

269 Although gE is well conserved among alphaherpesviruses, the amino terminus of VZV gE is uniq

270 For most alphaherpesviruses, the minimal set of viral proteins re

271 Together, the results suggest that among the alphaherpesviruses, there is variability in entry requir

272 ecificities as entry receptors for mammalian alphaherpesviruses through interaction with viral glycop

273 rate specificity for thymidine alone, unlike alphaherpesvirus thymidine kinases (TKs).

274 This transit in axons is essential for alphaherpesviruses to establish latency in ganglia and t

275 The contribution of chromatin insulators in alphaherpesvirus transcriptional control is less well un

276 r viral replication and, in the case of many alphaherpesviruses, transmission into the nervous system

277 lex-binding region to be ORF32, a homolog of alphaherpesvirus UL17.

278 rther localize ORF19 and ORF32 proteins (the alphaherpesvirus UL25 and UL17 homologs in KSHV, respect

279 y regarding the location and conformation of alphaherpesvirus UL25 protein inside the virion.

280 ding the virion location and conformation of alphaherpesvirus UL25 protein.

281 MDV glycoprotein C (gC) is encoded by the alphaherpesvirus UL44 homolog and is essential for the h

282 The alphaherpesvirus UL51 (pUL51) protein has been reported

283 The alphaherpesvirus UL51 protein is a tegument component th

284 Alphaherpesviruses, unlike beta- and gammaherpesviruses,

285 Us3 function and defines a new role for this alphaherpesvirus Us3 kinase in regulating MAPK activatio

286 ed that while HDAC2 is a conserved target of alphaherpesvirus US3 kinases, the functional significanc

287 The alphaherpesvirus Us4 gene encodes glycoprotein G (gG), w

288 these results indicate that both gamma- and alphaherpesviruses use a conserved RNR-dependent mechani

289 method for studying neuron-to-cell spread of alphaherpesviruses using a compartmented culture system.

290 ve epitopes and TCRs may be useful for multi-alphaherpesvirus vaccine design and adoptive cellular th

291 esviridae, including the medically important alphaherpesvirus varicella-zoster virus (VZV), induce fu

292 Like all alphaherpesviruses, varicella-zoster virus (VZV) infecti

293 These alphaherpesvirus vCKBPs represent a novel family of prot

294 functional and structural similarities with alphaherpesvirus VP22, underscoring the evolutionary imp

295 sis of this minireview is that the ancestral alphaherpesvirus VZV coevolved in simians, apes, and hom

296 ino acids within the scaffolding proteins of alphaherpesviruses were mutated, and the properties of t

297 ly conserved in the UL25 homologues of other alphaherpesviruses, were found to be critical for stable

298 x virus type 1 (HSV-1) are distantly related alphaherpesviruses whose natural hosts are pigs and huma

299 Varicella-zoster virus (VZV) is an alphaherpesvirus with the characteristic neurotropism of

300 s 1, bovine herpesvirus 1 and 5, and related alphaherpesviruses with no sequence similarity to chemok