ライフサイエンスコーパス: altered gene expression

1 APEX1 binding at -1651 of CYP11B2 results in altered gene expression.

2 i verify that disrupted STF binding leads to altered gene expression.

3 adversely affected by TNFalpha, resulting in altered gene expression.

4 localization of heterochromatin, leading to altered gene expression.

5 reflects changes in cellular composition and altered gene expression.

6 ained from cytogenetics, gene mutations, and altered gene expression.

7 further to aberrant chromatin remodeling and altered gene expression.

8 a model of aberrant DNA repair coupled with altered gene expression.

9 on of DNA G-quadruplexes (G4s) is coupled to altered gene expression.

10 Breast cancer progression is driven by altered gene expression.

11 sults in cell proliferation and dramatically altered gene expression.

12 to drug-induced and idiopathic lupus through altered gene expression.

13 ovarian atresia, reduced egg production, and altered gene expression.

14 uld directly transmute synaptic signals into altered gene expression.

15 eir concentration in the nucleus, leading to altered gene expression.

16 s show increased sarcomeric organization and altered gene expression.

17 ic hyperglycemia is the primary cause of the altered gene expression.

18 of CD40 are believed to be achieved through altered gene expression.

19 A Pol I transcription sites, also leading to altered gene expression.

20 proteasome-mediated degradation rather than altered gene expression.

21 strocyte activation around Abeta plaques and altered gene expression.

22 e of HB cells, evident by their behavior and altered gene expression.

23 tions associated with disease phenotypes and altered gene expression.

24 shed chromatin accessibility correlated with altered gene expression.

25 g of transcription factor to its target, and altered gene expression.

26 repeat expansion in the HTT gene, leading to altered gene expression.

27 logical and molecular adjustments, including altered gene expression.

28 ed histone 3 lysine 4 (H3K4) methylation and altered gene expression.

29 phenotypes of ADAR mutants can be caused by altered gene expression.

30 es and cause epigenetic changes that lead to altered gene expression.

31 preventing pleiotropic effects caused by its altered gene expression.

32 geted disruption of such elements results in altered gene expression.

33 promotes erythroid development, and reverses altered gene expression.

34 In contrast, it altered gene expression.

35 oth LOE genes and ASE events associated with altered gene expression.

36 n by inhibiting DNMT1 activity, resulting in altered gene expression.

37 eased proliferation, aberrant apoptosis, and altered gene expression.

38 ed changes in nucleosome occupancy result in altered gene expression?

39 a small minority of SVs are associated with altered gene expression(4,5), and it remains unclear why

40 t the idea that Cdk5 activity is involved in altered gene expression after chronic exposure to cocain

41 s provides the first comparative analysis of altered gene expression after infection with viruses of

42 In general, pair feeding altered gene expression after the 7-day treatment, where

43 iminution in stem cell pools, or, because of altered gene expression, an increased chance for stem ce

44 the two-week time point and correlated with altered gene expression and 5hmC profiles that mapped to

45 ageing is associated with reduced function, altered gene expression and a perturbed epigenome.

46 single Drosophila homolog dBRWD3 results in altered gene expression and aberrant patterns of histone

47 strides have been made in characterizing the altered gene expression and acquired genetic mutations i

48 F-beta1 gene promoter may be associated with altered gene expression and asthma phenotype.

49 idence suggests that these may contribute to altered gene expression and biologic processes that enha

50 ardiac myocytes and fibroblasts that lead to altered gene expression and cell remodelling under physi

51 n, the signal transduction events leading to altered gene expression and cellular activity are essent

52 t aging changes these structures, leading to altered gene expression and cellular dysfunction.

53 tially mediate signaling events that lead to altered gene expression and cellular function, and may r

54 isms that translate radiation responses into altered gene expression and cellular phenotype.

55 omA-induced behavioral deficits and identify altered gene expression and disrupted myelin structure a

56 or cells that GDM exposure in utero leads to altered gene expression and DNA methylation, suggesting

57 tating OFT and associated vessels results in altered gene expression and function of CNCCs and decrea

58 stress-inducible gene, in the heart leads to altered gene expression and impaired cardiac function.

59 d during differentiation, and TET1 knockdown altered gene expression and inhibited barrier formation

60 oxylase, providing a functional link between altered gene expression and intrinsic abnormalities in P

61 e resection significantly but differentially altered gene expression and kinetics of extracellular ma

62 loci have variants that could contribute to altered gene expression and liability.

63 Changes in diet result in altered gene expression and neuronal activity in the ARN

64 tic bases for differential susceptibility to altered gene expression and NTDs in diabetic mice may be

65 h SMC-specific knockdown of Mylk demonstrate altered gene expression and pathology consistent with me

66 eal epithelium revealed that USP10 knockdown altered gene expression and pathways controlling tissue

67 pe III methyltransferases is associated with altered gene expression and phenotypic variation.

68 e molecular effects of TE movements, such as altered gene expression and piRNA production.

69 with chromatin by depleting WIZ resulted in altered gene expression and protein-protein interactions

70 in sickle cell disease (SCD) contributes to altered gene expression and pulmonary hypertension, a co

71 lly active Dnmt1, lens epithelial cells have altered gene expression and reduced proliferation in bot

72 lation of high molecular weight aSyn species altered gene expression and reduced toxicity when compar

73 n m(6)A-modified regions are associated with altered gene expression and RNA splicing, suggesting tha

74 Altered gene expression and slight interstitial fibrosis

75 the salt-sensitive phenotype as well as the altered gene expression and splicing patterns in the mut

76 We found that almost all mutations altered gene expression and that parameters of gene expr

77 Epigenetic mechanisms contribute further to altered gene expression and therefore to the development

78 ncluding changes in DNA methylation, lead to altered gene expression and thus may underlie epileptoge

79 y 2,3,7,8-tetrachlorodibenzo-p-dioxin causes altered gene expression and toxicity.

80 -p-dioxin (TCDD) and related compounds cause altered gene expression and toxicity.

81 7,8-tetrachlorodibenzo-p-dioxin (TCDD) cause altered gene expression and toxicity.

82 rly UC, contributing to genetic instability, altered gene expression and tumor progression.

83 d associations of five of the GWAS loci with altered gene expression and two with CAD.

84 ime, begin to form duct-like structures with altered gene expression and ultrastructural properties.

85 ional deletion from mouse RPCs reduced 5hmC, altered gene expressions and disrupted retinal cell prol

86 sults in re-initiation of the DNA synthesis, altered gene expression, and apoptosis, but the signalin

87 -variant positive tumours have significantly altered gene expression, and are enriched for the lumina

88 RNase protection assay was used to measure altered gene expression, and enzyme-linked immunosorbent

89 r, these data link RS-mediated mtDNA damage, altered gene expression, and mitochondrial dysfunction i

90 ith those of the present study, suggest that altered gene expression, and not actin reorganization, i

91 lic changes resulting from genetic mutation, altered gene expression, and protein dysfunction in a gi

92 en MGEs can compromise bacterial fitness via altered gene expression, and we argue that conflicts bet

93 that IL6 promoter genotypes associated with altered gene expression are risk factors for development

94 DNMT3B7-expressing 293 cells have altered gene expression as identified by microarray anal

95 rough tyrosine kinase activation may lead to altered gene expression, as J393/CD43 ligation prompted

96 To detect altered gene expression associated with mouse lung tumor

97 We identified altered gene expression at all ages, including changes i

98 ethylated promoters that are associated with altered gene expression between neural stem cell (NSC) a

99 We found specific patterns of altered gene expression between TAC and SIH with GRK5 ov

100 led to an increase in intracellular calcium, altered gene expression, but had no effect upon wound re

101 ats perfused 5-7 d after TT injection showed altered gene expression, but the changes varied in their

102 n synaptic function cannot be predicted from altered gene expressions, but determining the amount, de

103 The mechanisms of cell signaling and altered gene expression by asbestos, a potent inflammato

104 Both processes are also modulated by altered gene expression by resident cells and by the rel

105 in genetic programming is unclear; however, altered gene expression by temperature-dependent changes

106 of genome-wide DNA methylation levels and of altered gene expression caused by epialleles.

107 gulated autophagy over the diurnal cycle and altered gene expression causing abnormal circadian wheel

108 ity, and examination for genetic mutation or altered gene expression characteristics of the correspon

109 RNA miR-22 motif) and promoter polymorphisms altered gene expression consistent with the decline in S

110 rogramming followed a stereotyped pattern of altered gene expression consisting of robust induction o

111 d by surface changes, uptake, signaling, and altered gene expression, contributing to homeostasis, ho

112 haracterized by transient cell cycle arrest, altered gene expression, degradation of nutrient permeas

113 In addition to altered gene expression, DNA hypomethylation results in

114 with renal cells has been shown to result in altered gene expression, DNA synthesis, and cell death.

115 develops dysfunction, reduction in mass, and altered gene expression, due to atrophic remodeling.

116 has been strengthened through description of altered gene expression during biotin deficiency and thr

117 cause familial forms of the disease, and 2) altered gene expression during the disease state.

118 In addition, the phenotypes resulting from altered gene expression (e.g. in genetically altered ani

119 d by HER2 overexpression activated Stat3 and altered gene expression, enforcing an autocrine loop of

120 Altered gene expression extended to other brain regions

121 Experimental validation further confirmed altered gene expression following ALKBH5 knockdown, cons

122 ion, five polymorphisms were associated with altered gene expression following doxorubicin treatment.

123 Altered gene expression for a number of molecules has be

124 s respond to traumatic brain injury (TBI) by altered gene expression, hypertrophy and proliferation t

125 educed cAMP levels threefold and resulted in altered gene expression, impaired bioenergetics, and a d

126 candidate genes in the associated loci have altered gene expression in 9 different gene perturbation

127 ain organoids revealed that the loss of FMRP altered gene expression in a cell-type-specific manner.

128 this new gene expression screen to identify altered gene expression in a complex in vivo environment

129 n many research institutes and found that it altered gene expression in a previous study of zebrafish

130 Cellular exposure to hypoxia results in altered gene expression in a range of physiologic and pa

131 The mechanism by which altered gene expression in adipose tissue affects liver

132 Together our results show: (a) an altered gene expression in carriers of the susceptible C

133 ant promoter methylation was associated with altered gene expression in CRC, this was not the case in

134 Finally, we successfully altered gene expression in cultured human PAX7+ satellit

135 equencing unveiled morphological changes and altered gene expression in deletion mutants of two N-myr

136 mals and allows evaluation of the effects of altered gene expression in differentiated cell types in

137 e characteristic drug 'signature' pattern of altered gene expression in drug-treated cells with a mut

138 Altered gene expression in hematopoietic progenitors may

139 of these were significantly associated with altered gene expression in human adipose, more than woul

140 o examine how wild-type (wt) HPIV1 infection altered gene expression in human respiratory epithelial

141 This comprehensive description of altered gene expression in isolated IPF fibroblasts unde

142 central nervous system, isolated rats showed altered gene expression in key brain regions associated

143 letion in the gene for PML (KO mice) exhibit altered gene expression in liver, adipose tissue, and sk

144 upregulation of genes involved in apoptosis, altered gene expression in metabolic pathways, and the d

145 establish DNA methylation as a mechanism of altered gene expression in MS hippocampus.

146 Probiotic ingestion altered gene expression in multiple canonical pathways i

147 ies the link between blood-derived mtDNA-CN, altered gene expression in multiple tissues, and aging-r

148 Our data provide a basis for studying altered gene expression in myeloid disorders using mouse

149 l association between RB-E2F dysfunction and altered gene expression in osteosarcoma.

150 ontractility within collagen gels and led to altered gene expression in pathways governing adhesion a

151 The most significantly altered gene expression in patients with PTSD relative t

152 Furthermore, this variant is associated with altered gene expression in peripheral blood and altered

153 ngle-cell antisense RNA approach to identify altered gene expression in postmortem AD brain, followed

154 leading to increased protein acetylation and altered gene expression in prostate and ovarian cancer c

155 n the CCLE dataset, hundreds of genes showed altered gene expression in relation to nearby SV breakpo

156 used to profile transcriptomes and discover altered gene expression in saliva supernatant.

157 ved after preterm birth were associated with altered gene expression in specific developmental cell p

158 Wound repair in the liver induces altered gene expression in stellate cells (resident mese

159 The aim was to identify the extent of altered gene expression in term placentas from pregnant

160 Altered gene expression in the 5xFAD hippocampus is also

161 Further studies on altered gene expression in the blast-injured rat cochlea

162 at the absence of SigB or SigD predominately altered gene expression in the dark or in the light, res

163 rapid appearance of periodic arrangements of altered gene expression in the epidermis and prominent c

164 maternal nutrient restriction significantly altered gene expression in the fetal cardiac left ventri

165 nd MEF2C each programmed similar profiles of altered gene expression in the heart that included extra

166 terning allows a better understanding of how altered gene expression in the hippocampus contributes t

167 est an important role for decreased ARNT and altered gene expression in the impaired islet function o

168 ese changes in cell fate are associated with altered gene expression in the intestine and remodeling

169 y of >5000 mouse expressed sequence tags for altered gene expression in the livers of two lines of mi

170 ing and interfered with DNA looping, causing altered gene expression in the neighboring loop.

171 e response is usually manifested in terms of altered gene expression in the nucleus.

172 pread epigenetic instability associated with altered gene expression in the placentas of wild-type gr

173 frequently accompanied by hypometabolism and altered gene expression in the prefrontal cortex.

174 ute responses to alcohol in progenitor cells altered gene expression in their descendant neurons.

175 Altered gene expression in this tissue does not appear t

176 We showed altered gene expression in TILs in FL and demonstrated t

177 Further, RNA sequencing analysis revealed altered gene expression in Tph1 deficient ILC2s includin

178 by microarray analysis to be involved in the altered gene expression in vectorless gravity, the data

179 ohol dehydrogenase (ADHIB) and evaluated for altered gene expression in vitro and metabolic activity

180 Adhesion to OPN altered gene expression, in particular genes involved wi

181 Biological pathways showing early altered gene expression included: lipid metabolism, cyto

182 RNA-binding protein, loss of RBM12 leads to altered gene expression, including that of multiple effe

183 titution of cohesin function largely rescues altered gene expression, including the expression of gen

184 Most core promoter shifts are coupled with altered gene expression, indicating that alternative cor

185 cted as changes in synaptic transmission and altered gene expression, indicating that restoring synap

186 Mutations, genetic translocations and altered gene expression involving these KMTs are frequen

187 The altered gene expression is associated with dysregulated

188 re weeks to develop in rats, suggesting that altered gene expression is involved.

189 Altered gene expression is presumed to be due to interac

190 sought to determine whether this pattern of altered gene expression is restricted to the dorsolatera

191 from both injury models, at least 50% of the altered gene expression is specific to a given injury ty

192 rogenitors and erythropoiesis, indicating an altered gene-expression landscape.

193 This deficiency results in altered gene expression leading to physiological and mor

194 ferentiated ZBTB18-null cells have radically altered gene expression, leading to cytoskeletal defects

195 ve sarcoplasmic reticulum Ca(2+) release and altered gene expression, leads to cardiac hypertrophy an

196 The lack of LMO2 resulted in altered gene expression levels already at the haemangiob

197 These phenotypes are associated with the altered gene expression levels of FCA, WUS, and CUC1.

198 In non-stroke animals gemfibrozil also altered gene expression levels of PPARs in both the aort

199 bitor-mediated changes were not reflected in altered gene expression levels of the genes involved in

200 ethylation, deregulated histone acetylation, altered gene expression levels, distorted microRNA profi

201 to identify associations between smoking and altered gene expression levels.

202 iptional effect level index) that integrates altered gene expression magnitude over the exposure time

203 studies have shown that integration-induced altered gene expression may be associated with tumor rec

204 Altered gene expression may be the earliest mediator of

205 These findings suggest that altered gene expression may result from the interactions

206 To determine whether altered gene expression might account for long term chan

207 This altered gene expression might suggest a role for ADIPOR1

208 atin in an imbalanced manner, it can lead to altered gene expression, mitotic errors, and death [4-6]

209 rmal monocyte gene-expression levels with an altered gene-expression network due to gene-environment

210 n murine lung tumors and its relationship to altered gene expression observed during embryogenesis an

211 hole genome bisulphite sequencing linked the altered gene expression observed in mutant cells to thei

212 ted with systemic lupus erythematosus (SLE), altered gene expression of C1QB and five type I interfer

213 trix (Santa Clara, CA) gene chip technology, altered gene expression of different end effector molecu

214 lection of aggressively expanding cells with altered gene expression of integrated HPV genomes and po

215 ys became prominent in TGo, concomitant with altered gene expression of K(+)-channel subunits and ion

216 Morphological diversity is often caused by altered gene expression of key developmental regulators.

217 in GFAP-positive cells in the G-KiR-KO mouse altered gene expression of key factors in PGE2 synthesis

218 Furthermore, B4 knockdown altered gene expression of key genes of lens differentia

219 ion with IPF susceptibility (associated with altered gene expression of KIF15, MAD1L1, and DEPTOR) an

220 metabolic disorders in the F1 offspring and altered gene expression of metabolic pathways in early e

221 e to reduced mitochondrial Ca(2+) uptake and altered gene expression of proapoptotic and antiapoptoti

222 We found altered gene expression of various cell cycle regulators

223 ticularly useful for studying the effects of altered gene expression on cardiac development and in th

224 s development, physiology or defence through altered gene expression or by direct influences on other

225 eoplasms is often associated with mutations, altered gene expression or chromosomal translocations.

226 ntrolling plant development, which result in altered gene expression or loss of gene function.

227 based diagnosis tools for diseases caused by altered gene expression, or used for further network ana

228 FD-fed Galpha(z) KO mice have a dramatically altered gene expression pattern as compared with WT HFD-

229 om HFD-fed Ga(z) KO mice have a dramatically altered gene expression pattern as compared with WT HFD-

230 igand rosiglitazone partially normalizes the altered gene expression pattern associated with Cftr def

231 with DCM >6 years of age showed a profoundly altered gene expression pattern with enrichment of genes

232 ors carrying the GFI136N variant allele have altered gene expression patterns and differ in their abi

233 o understand the many processes that dictate altered gene expression patterns and post-transcriptiona

234 In various human diseases, altered gene expression patterns are often the result of

235 Recently, using cDNA microarrays, altered gene expression patterns between subjects with s

236 d single cell RNA-seq to globally define the altered gene expression patterns in all developing uteru

237 rst exons is known to play a key role in the altered gene expression patterns in all human cancers.

238 acterial and viral infections, respectively, altered gene expression patterns in taste bud cells.

239 in the forebrain neuroectoderm, we observed altered gene expression patterns in the facial ectoderm.

240 her they shared functional abnormalities and altered gene expression patterns that differed from thos

241 analyses provide a high-quality resource of altered gene expression patterns under severe OXPHOS def

242 rmore, we show that the Osr2 mutants exhibit altered gene expression patterns, including those of Osr

243 1 leads to epithelial cell proliferation and altered gene expression patterns.

244 gan pathology, biochemical abnormalities and altered gene expression patterns.

245 process resulting in contaminated cells with altered gene expression patterns.

246 s prevented adaptation, suggesting that Mdm2 altered gene expression, possibly through its well known

247 The findings of altered gene expression prior to the development of any

248 The altered gene expression profile caused by reducing histo

249 lecular synergy manifested as a dramatically altered gene expression profile in Npm1(cA);Flt3(ITD) ,

250 study, we show that lack of DCs leads to an altered gene expression profile in peripheral but not th

251 oduce CCL17 and CCL22, consistent with their altered gene expression profile in the absence of IRF4.

252 RNA from null and wild-type mice revealed an altered gene expression profile with the up-regulation o

253 and pro-inflammatory features matched by an altered gene expression profile.

254 R expression in human RKO colon cancer cells altered gene expression profiles and identified beta-cat

255 These cells exhibit altered gene expression profiles and serve as a barrier,

256 e placental disruptions were associated with altered gene expression profiles in the male fetal brain

257 r in Western societies, dietary-induced risk altered gene expression profiles predominantly in villus

258 ) cells had reduced suppressor activity with altered gene expression profiles, including reduced expr

259 ylase chromatin remodeling complex, leads to altered gene expression profiles.

260 icromol/L, respectively, and correlated with altered gene expression profiles.

261 tissue, thus providing a spatial context to altered gene expression profiles.

262 NMP altered gene-expression profiles of liver tissue from pr

263 An analysis of the temporal sequence of altered gene expression provides further information tha

264 CRF and GR gene methylation correlated with altered gene expression, providing important evidence of

265 Another one employs an integrated altered gene expression quantifier-TELI (transcriptional

266 red Rho-GTPase signaling, as demonstrated by altered gene expression, reduced assembly of F-actin fib

267 ship between D409V dosage, and the degree of altered gene expression related to lysosome dysfunction,

268 e remodeling in the BZ is driven by uniquely altered gene expression, related to heterogeneity in the

269 Like contextual memory formation, this altered gene expression required NMDA receptor activatio

270 e at relatively hypomethylated loci, and the altered gene expression resulted from de novo centromere

271 impairs insulin-mediated NO production, and altered gene expression resulted from eNOS instability,

272 Altered gene expression resulting from YAP/TAZ inhibitio

273 cterized by chromosomal abnormalities and an altered gene expression signature; however, the mechanis

274 hen expressed, it promotes tumorigenesis via altered gene expression, stimulating epithelial-mesenchy

275 The mechanism of HAH toxicity involves altered gene expression subsequent to activation of the

276 r dendritic cell (FDC) cluster dispersal and altered gene expression suggested poor function.

277 T1pSer143 that regulates DNA methylation and altered gene expression that contributes to cell invasio

278 red to obese European Americans, we observed altered gene expression that may explain known differenc

279 rm development based on the dynamics of SHB1-altered gene expression, the magnitude of SHB1 chromatin

280 in Jmjd3-deficient cells are correlated with altered gene expression through interactions with specif

281 One possible consequence of aneuploidy is altered gene expression through loss of heterozygosity (

282 Because galls require altered gene expression to change cell fates, their init

283 thus enabling transfection experiments that altered gene expression to explore the molecular mechani

284 n primary afferent neurons to result from an altered gene expression triggered by cytokines/growth fa

285 hances tumor growth in cholangiocarcinoma by altered gene expression via autocrine mechanisms.

286 Altered gene expression was confirmed by quantitative PC

287 Functional classification of altered gene expression was consistent with a role for S

288 Altered gene expression was consistent with CDK8/19 inhi

289 es were identified, the temporal sequence of altered gene expression was determined by monitoring the

290 Significantly altered gene expression was determined by multiclass ana

291 This altered gene expression was discovered by microarray ana

292 The altered gene expression was partly due to glucose restri

293 The altered gene expression was partly rescued by knockdown

294 In light of this altered gene expression, we probed the effects of these

295 Significant and bidirectional predictions of altered gene expression were identified in amygdala betw

296 to defects in imprint establishment causing altered gene expression, which could contribute to healt

297 ioning and histone modifications, leading to altered gene expression, which is likely the cause of th

298 ivation of nuclear transcription factors and altered gene expression within the liver, leading to the

299 rization from surrounding vessels and causes altered gene expression within vascular cells.

300 haride accumulate 5hmC at enhancers and show altered gene expression without DNA demethylation; loss