ライフサイエンスコーパス: alveolar fluid

1 ired for active near-isosmolar absorption of alveolar fluid.

2 in the recognition of Aspergillus conidia in alveolar fluid.

3 roteoglycan, and KC, a CXC chemokine, in the alveolar fluid.

4 Active, near-isosmolar alveolar fluid absorption (Jv) was measured in in situ p

5 Active alveolar fluid absorption was measured in an in situ lun

6 It also shows that alveolar fluid accumulation in pneumonia, wall thickenin

7 Inhibition of ENaC by amiloride reproduced alveolar fluid and Cl(-) secretion that were again CFTR-

8 tibodies, we found H3.3 in the airway lumen, alveolar fluid, and plasma of COPD samples.

9 ected in resident macrophages and monocytes, alveolar fluid, and the endothelium of blood vessels in

10 may contribute significantly in maintaining alveolar fluid balance and in resolving airspace edema.

11 plays a critical role in the maintenance of alveolar fluid balance.

12 ant ion channels that maintain bronchial and alveolar fluid balance: the cystic fibrosis transmembran

13 energic agonists accelerate the clearance of alveolar fluid by increasing the expression and activity

14 tant, or hyaluronan, normally present in the alveolar fluids, can enhance adsorption in the presence

15 Of the patients, 56% had impaired alveolar fluid clearance (< 3%/h), 32% had submaximal cl

16 mild pulmonary oedema (24/29 [83%]), intact alveolar fluid clearance (17/23 [74%]), and normal or mi

17 ith serial samples, there was a high rate of alveolar fluid clearance (19 +/- 9%/h, mean +/- SD).

18 lar epithelial dysfunction, as determined by alveolar fluid clearance (AFC) and intra-alveolar levels

19 Furthermore, measurement of alveolar fluid clearance (AFC) demonstrated that A2BAR s

20 h acute lung injury (ALI) who retain maximal alveolar fluid clearance (AFC) have better clinical outc

21 Moreover, induced Na,K-ATPase improved alveolar fluid clearance (AFC) in IAV-infected mice.

22 of the NO donor, DETANONOate, would decrease alveolar fluid clearance (AFC) in the rabbit in vivo.

23 nfected with M. pulmonis for measurements of alveolar fluid clearance (AFC) in vivo and isolation of

24 reactive byproducts inhibit Na(+)-dependent alveolar fluid clearance (AFC) in vivo and the activity

25 Alveolar fluid clearance (AFC) is necessary for the reso

26 Whether these receptors are essential for alveolar fluid clearance (AFC) or if other mechanisms ar

27 by alveolar edema accumulation with reduced alveolar fluid clearance (AFC), alveolar-capillary barri

28 Alveolar fluid clearance (AFC), an index of active Na(+)

29 Alveolar fluid clearance (AFC), an index of alveolar act

30 A(2a)R- or A(3)R-specific agonists increased alveolar fluid clearance (AFC), whereas physiologic conc

31 g the inhibition of the c-AMP stimulation of alveolar fluid clearance (ALC) in rats.

32 3) and in patients with an absence of intact alveolar fluid clearance (p =.03).

33 ing demonstrated a positive correlation with alveolar fluid clearance (Spearman rank correlation [r(s

34 aspiration-induced lung injury by increasing alveolar fluid clearance and decreasing endothelial perm

35 hese data suggest that claudin-4 may promote alveolar fluid clearance and demonstrate that the amount

36 subunit plasmid showed a twofold increase in alveolar fluid clearance and Na(+),K(+)-ATPase activity

37 ce to lung injury, db/db mice had diminished alveolar fluid clearance and reduced Na,K-ATPase functio

38 In isolated perfused lungs, alveolar fluid clearance and secretion were determined b

39 panied by a 2.4-fold increase in the rate of alveolar fluid clearance at 4 hrs in the salmeterol-trea

40 Recently, we showed that impairment of alveolar fluid clearance because of inhibition of epithe

41 with control, LTD4 (1 x 10(-11) M) increased alveolar fluid clearance by 41% (p < 0.001) in isolated,

42 in BALB/c mice increased amiloride-sensitive alveolar fluid clearance by approximately 30%, consisten

43 ung and restored the normal up-regulation of alveolar fluid clearance by catecholamines after prolong

44 e lung prevented the normal up-regulation of alveolar fluid clearance by catecholamines following hem

45 Alveolar fluid clearance contributes to graft function a

46 Intact alveolar fluid clearance correlated with less histologic

47 Because a decrease in net alveolar fluid clearance could be due to lung endothelia

48 Alveolar fluid clearance driven by active epithelial Na(

49 The two patients with no net alveolar fluid clearance had persistent hypoxemia and mo

50 Patients with maximal alveolar fluid clearance had significantly lower mortali

51 edema and acute lung injury, we measured net alveolar fluid clearance in 79 patients with acute lung

52 -mediated inhibition of beta-agonist-induced alveolar fluid clearance in a murine model of trauma-sho

53 ring the beta- adrenergic agonist-stimulated alveolar fluid clearance in acute lung injury, an effect

54 The unimpaired alveolar fluid clearance in AQP5-null mice indicates tha

55 nfection has been shown to reduce Na+-driven alveolar fluid clearance in BALB/c mice in vivo.

56 g injury and the loss of claudin-4 decreases alveolar fluid clearance in mice.

57 in contrast to hydrostatic pulmonary edema, alveolar fluid clearance in patients with acute lung inj

58 K-ATPase in alveolar epithelial cells and on alveolar fluid clearance in rat lungs.

59 The high rates of alveolar fluid clearance indicate that the fluid transpo

60 red in the majority of patients, and maximal alveolar fluid clearance is associated with better clini

61 Airway and alveolar fluid clearance is mainly governed by vectorial

62 However, impaired alveolar fluid clearance is present in most of the patie

63 Measurement of alveolar fluid clearance may be useful to assess the sev

64 ins (including ZO-1) was not associated with alveolar fluid clearance or claudin-4 levels.

65 nction protein claudin-4 are associated with alveolar fluid clearance or clinical measures of lung fu

66 Maximal cAMP-dependent alveolar fluid clearance rate was 32.9 +/- 10.9 %/hr (p

67 Alveolar fluid clearance rates were measured in ex vivo

68 ts with acute lung injury (ALI) have reduced alveolar fluid clearance that has been associated with h

69 , and isoproterenol 10(-6) M each stimulated alveolar fluid clearance to a level comparable to maxima

70 -grade human mesenchymal stem cells restored alveolar fluid clearance to a normal level, decreased in

71 across the alveolar epithelium and restored alveolar fluid clearance to normal.

72 th hydrostatic pulmonary edema, in whom mean alveolar fluid clearance was 13%/h; only 25% had impaire

73 Mean alveolar fluid clearance was 6%/h.

74 Basal alveolar fluid clearance was 7.6 +/- 2.2 %/hr.

75 Net alveolar fluid clearance was calculated from sequential

76 Alveolar fluid clearance was calculated from serial samp

77 Compared with basal rates, alveolar fluid clearance was increased by both racemic a

78 Alveolar fluid clearance was measured by change in conce

79 Alveolar fluid clearance was measured in anesthetized, v

80 Alveolar fluid clearance was measured in living ventilat

81 Alveolar fluid clearance was measured in vivo.

82 r without electroporation, and 3 days later, alveolar fluid clearance was measured.

83 Alveolar fluid clearance was preserved in SP-C-GM mice i

84 Acute lung injury with maximal alveolar fluid clearance were more likely to be female (

85 nce, fibrinogenesis, inflammatory cytokines, alveolar fluid clearance, and endothelial injury and act

86 human lungs, mesenchymal stem cells restored alveolar fluid clearance, reduced inflammation, and exer

87 Concomitantly, we observed a reversal of alveolar fluid clearance, suggesting that reversed trans

88 eduction of Na,K-ATPase expression decreases alveolar fluid clearance, which in turn leads to pulmona

89 by reducing lung inflammation and enhancing alveolar fluid clearance.

90 nary edema by up-regulating sodium-dependent alveolar fluid clearance.

91 genous catecholamines did not correlate with alveolar fluid clearance.

92 in and an approximately 50% reduction in net alveolar fluid clearance.

93 id instillation led to a 50% decrease in net alveolar fluid clearance.

94 ANTU-induced edema formation by potentiating alveolar fluid clearance.

95 e may be of more benefit than improvement of alveolar fluid clearance.

96 eolar epithelial fluid transport measured as alveolar fluid clearance.

97 ndothelial barrier permeability and restored alveolar fluid clearance.

98 mechanisms may contribute to the decrease in alveolar fluid clearance.

99 bited both basal and beta agonist-stimulated alveolar fluid clearance.

100 is, neutrophil activation and clearance, and alveolar fluid clearance.

101 elial permeability to protein, and decreased alveolar fluid clearance.

102 ed elevated lung inflammation and attenuated alveolar fluid clearance.

103 a level comparable to maximal cAMP-dependent alveolar fluid clearance.

104 samples were associated with slower rates of alveolar fluid clearance.

105 a regulator of MMP-12 reuptake from broncho-alveolar fluid, driving in two independently generated T

106 istent with permeability edema and increased alveolar fluid export.

107 high concentrations of IL-8 were present in alveolar fluids from patients with ARDS and were associa

108 ive ion transport that is needed to maintain alveolar fluid homeostasis during pulmonary edema.

109 gamma-aminobutyric acid receptors involving alveolar fluid homeostasis in adult lungs.

110 hat betaAR signaling may not be required for alveolar fluid homeostasis in uninjured lungs.

111 Alveolar fluid homeostasis is regulated by Na+/K+-ATPase

112 control of respiration, protein maturation, alveolar fluid homeostasis, wound repair, innate immunit

113 fluid from the fetal lung and in reabsorbing alveolar fluid in the injured adult lung.

114 Light microscopy showed gross alveolar fluid in three apneic dogs, and electron micros

115 ute respiratory distress syndrome (ALI/ARDS) alveolar fluid induces KGF and fibroblast genes importan

116 holipase A(2) concentration increases in the alveolar fluids leading to the hydrolysis of bacterial,

117 The deficiency of total GSH in the alveolar fluid may predispose lung allografts to extrace

118 Production of TNF-alpha in lung alveolar fluids of mice infected with B. dermatitidis wa

119 tion of either hyaluronan (normally found in alveolar fluid) or polyethylene glycol to subphases cont

120 ht heart catheterization and the sampling of alveolar fluid protein are sometimes necessary.

121 med with wet/dry lung weight ratios, and the alveolar fluid protein concentration was measured after

122 for up to 24 h and then measured changes in alveolar fluid reabsorption (AFR) and Na,K-ATPase functi

123 nce of poor alveolar ventilation and impairs alveolar fluid reabsorption (AFR) by promoting Na,K-ATPa

124 We found that alveolar fluid reabsorption after 1 hour was impaired by

125 Hypoxia inhibits alveolar fluid reabsorption and decreases Na,K-ATPase ac

126 c alpha(1) agonist, phenylephrine, increased alveolar fluid reabsorption by 54 and 40%, respectively,

127 ion in rat lungs prevented the impairment of alveolar fluid reabsorption caused by hypoxia.

128 gest that beta-adrenergic agonists increased alveolar fluid reabsorption in rats ventilated with HVT

129 losis (hypocapnic or metabolic alkalosis) on alveolar fluid reabsorption in the isolated and continuo

130 Alveolar fluid reabsorption increased approximately twof

131 We report here that NE increased alveolar fluid reabsorption via the activation of both a

132 The hypocapnia-mediated decrease of alveolar fluid reabsorption was associated with decrease

133 The effect of low PCO2 on alveolar fluid reabsorption was reversible because clear

134 veolar epithelial Na,K-ATPase and increasing alveolar fluid reabsorption, cysteinyl leukotrienes may,

135 -adrenergic receptor agonists have a role in alveolar fluid reabsorption, via Na,K-ATPase, in the alv

136 pocapnic but not metabolic alkalosis impairs alveolar fluid reabsorption.

137 bitor, prevented the NE-mediated increase in alveolar fluid reabsorption.

138 s that reduce alveolar inflammation, enhance alveolar fluid removal, and reduce pulmonary fibrosis wi

139 fluid and showed that PRELP can be found in alveolar fluid, resident macrophages/monocytes, myofibro

140 The mechanisms of alveolar fluid resorption are different from those of al

141 Alveolar fluid resorption into the vessels is brought ab

142 ort across the alveolar epithelium, and thus alveolar fluid resorption, is regulated by apical Na+ ch

143 and the Na,K-ATPase giving rise to increased alveolar fluid resorption.

144 drostatic pressure induced ouabain-sensitive alveolar fluid secretion that coincided with transepithe

145 (+)-K(+)-Cl(-) cotransporters (NKCC) blocked alveolar fluid secretion, and lungs of CFTR(-/-) mice we

146 ort may promote lung edema by driving active alveolar fluid secretion.

147 ALI/ARDS alveolar fluid suppresses KGF expression, in part, due t

148 otein concentration and neutrophil counts in alveolar fluid through bronchoalveolar lavage, reduced e

149 f proteinaceous fluid, and inhibition of net alveolar fluid transport responsible for resolution of p