ライフサイエンスコーパス: aminate

1 dary, and primary C-H bonds are successfully aminated.

2 ure and functionality of the substrate to be aminated.

3 deposited using pyrophoric AlH(3) etherates/aminates.

4 g APIs, and an extension to the synthesis of aminated 1,3,4-oxadiazoles using N-benzoyloxy amine coup

5 The method selectively aminates 2 degrees benzylic C(sp(3))-H bond over the 3 d

6 Aminated 23 bases single stranded DNA (NH2-ssDNA) probe

7 ydrogenase (engineered from Bacillus sp.) to aminate a structurally diverse range of aromatic and ali

8 These catalysts can aminate a variety of benzylic, allylic and aliphatic C-H

9 strate the utility of this transformation by aminating a large set of terpenoids in high yield and re

10 ia coli and had both pyruvate and glyoxylate aminating activities.

11 found to selectively occur and give the beta-aminated adduct.

12 ansfer involving the combination of a chiral aminating agent 1 with a chiral rhodium catalyst 2.

13 d using N-methyl-O-tosylhydroxylamine as the aminating agent in the presence of a Cu(OTf)(2) catalyst

14 the presence of an ortho nitro group in the aminating agent plays a critical role in lowering the fr

15 on the generation of a potent electrophilic aminating agent released by in situ deprotection of O-Ts

16 ha-diimines using ethyl nosyloxycarbamate as aminating agent yields symmetrically functionalized bidi

17 lly simple, requires only a slight excess of aminating agent, proceeds under neutral or basic conditi

18 e as a C1 source of the amidine group and an aminating agent.

19 free cyclic secondary amines and anilines as aminating agents and inexpensive copper acetate makes th

20 A wide range of electrophilic aminating agents are now available, and these underpin a

21 highlight the strategic use of electrophilic aminating agents in total synthesis.

22 NH2/NH(alkyl)-O-(sulfonyl)hydroxylamines as aminating agents; the relatively weak RSO2O-N bond funct

23 is modulated by noncovalent interactions of aminated allylic intermediates.

24 An aminated Amberlite XAD-resin as a solid phase extractant

25 icient synthesis of the C(3) oxygenated/C(4) aminated analogues has been developed that furnishes the

26 directed evolution of enzymes to selectively aminate and amidate unactivated C(sp(3))-H sites.

27 ive transformation of nitroarenes into ortho-aminated and -annulated products is reported.

28 finic substrates, such as styrene, to afford aminated and aziridinated products, respectively.

29 In this work, the aminated aptamer selected for hydroxylated polychlorinat

30 wed by the assembly of IrO2 NPs on which the aminated aptamer selective to OTA is exchanged with the

31 ches, followed by chemical immobilisation of aminated-aptamer.

32 Dozens of previously unknown aminated arynes, including pyridynes, are generated in t

33 alpha-ketoisocaproate, which is reductively aminated back to L-leucine by leucine dehydrogenase in t

34 ates an iron-nitrene intermediate capable of aminating benzylic and allylic alpha-C-H bonds of carbox

35 New fluorous enantiopure (S)-alpha-aminated beta-keto esters were prepared through a highly

36 s of packed-bed modules containing different aminating biocatalysts which accordingly produced a rang

37 When indanone beta-ketoesters are aminated by DNIBX, the resulting products undergo diverg

38 clization of 1,6-enynes for the synthesis of aminated C-3 aryloylated benzofuran, furopyridine, benzo

39 The aminated capsules were effectively applied as a novel te

40 n of 7 times the value obtained with the non-aminated catalyst.

41 C synthase, SgcD has retained the ability to aminate chorismate identically to that observed for ASI.

42 T2L1 and AGXT2L2 acted on phosphorylated and aminated compounds.

43 90 h at 30 degrees C and pH 3, while its non-aminated counterpart retained 80 and 52 % of alpha-rhamn

44 lenic sulfamates into densely functionalized aminated cycloheptenes, where the relative stereochemist

45 ties and allows the synthesis of diversified aminated cyclopentene and cyclopentane derivatives being

46 including more than 20 drug molecules, were aminated, demonstrating the practicality and generality

47 While aminated dextran-coated IONPs directly absorb C3b and ac

48 onic 2-aza-Cope rearrangement to deconstruct aminated diene polymers.

49 The use of aminated DNA probes eliminates the need for proteins (su

50 A broad scope of compounds can be aminated encompassing numerous arene substitutions, amid

51 catalytically dehydrogenate cyclohexene, and aminate ethylene via nitrene transfer at or below room t

52 hieving a blending of effects, [Mn((t)BuPc)] aminates even 1 degrees aliphatic and propargylic C-H bo

53 h, and reproduction reduced in the order +ve aminated > neutral unfunctionalized -ve carboxylated wit

54 ylene glycol (PEG) as a functional layer and aminated hairpin nucleic acid molecules as target-specif

55 This protocol provides a wide range of aminated hydrazone derivatives in a step and atom econom

56 different substituted imidazoles have been N-aminated in this manner.

57 The Pd-catalyzed aminated intermediate was isolated and characterized.

58 Aminated linkers are known to enhance the absorption of

59 ted the electronic structure of MIL-125 with aminated linkers.

60 We further demonstrate that the N-aminated macrocycles block the prion-like cellular seedi

61 f immobilized animal and vegetable rennet on aminated magnetic particles, which has been proven to be

62 r the synthesis of functional and responsive aminated materials.

63 used to evaluate the deamination rate of the aminated-methylidene imidazolone (NH(2)-MIO) adduct of a

64 ious bacterial samples, where the pre-loaded aminated microspheres differentiated their flow velociti

65 It required only a blank paper chip, aminated microspheres, and a smartphone, with a rapid as

66 traction from used nuclear fuel, a series of aminated mono-1,2,4-triazinylpyridines were required.

67 The preparation of aminated monolayers with a controlled density of functio

68 he performance of lysozyme adsorption by the aminated nanofiber membrane immobilized with Reactive Gr

69 s modifying functionalization (postive (+ve) aminated; neutral unfunctionalized; negative (-ve) carbo

70 Carboxylated (COOH) and aminated (NH2) polystyrene microspheres were distributed

71 Aminated nitrogen heterocycles are valuable motifs acros

72 re larger for the thiolated NPs than for the aminated NPs, by 40% and 30%, respectively.

73 ted NPs that is only 20% longer than that of aminated NPs.

74 es containing a variety of substitution were aminated on nitrogen with isolated yields ranging from 4

75 and surface properties of the plastic, with aminated particles ingested and retained more frequently

76 e describe a practical synthesis of backbone aminated peptides that readily adopt beta-sheet folds.

77 Several C-terminal aminated peptides, including the model morphiceptin (YPF

78 for the solid-phase synthesis of backbone-N-aminated peptides.

79 es E, B, C, A and echinochrome A), and three aminated PHNQ compounds (spinamine E, echinamines A and

80 o degradation on exposure to light, with the aminated PHNQ pigments being the least stable.

81 It is found that the electroosmotic flow in aminated PMMA microchannels is reversed when compared to

82 bstrate via a glutardialdehyde linkage to an aminated-PMMA surface.

83 (TA), low-toxic cationic PGEA (ethanolamine-aminated poly(glycidyl methacrylate)) and type IV collag

84 The DNA delivery system consisted of aminated (poly-L-lysine-conjugated) dextran chains ancho

85 ile (lipophilic amines) or covalently bound (aminated-poly-(vinyl chloride)) hydrogen ion carriers is

86 Herein, we offer an aminated polyethersulfone nanofiber-expanded human umbil

87 m 58,100 to approximately 400 g mol(-1), and aminated post-consumer rubber is deconstructed over 6 ho

88 A naringinase complex was chemically aminated prior to its immobilization on glyoxyl-agarose

89 ric lactol acetates (3) produced the desired aminated products (6a-d) and recovered acetate (alpha-3)

90 s are mild and operationally simple, and the aminated products are produced in good to excellent yiel

91 nitrogen nucleophiles leads to a mixture of aminated products arising from substitution of fluorine

92 ide pattern, various differently substituted aminated products can be obtained.

93 Subsequent reaction of representative 4-aminated products gave 4,5-disubstituted systems and rin

94 fication of C(sp(3))-H bonds to a library of aminated products.

95 guanosine and 2'-deoxyguanosine but no other aminated purines, pyrimidines, or pterines.

96 c surfactants on pH electrodes prepared with aminated-PVC membranes is shown to be more complex, with

97 We describe a strategy for aminating pyridines and other azines via phosphonium sal

98 (1) (salen = N,N'-ethylene-bis-salicylidene aminate) reacts catalytically with thiiranes and convert

99 ovel synthetic application of the well-known aminating reagent hydroxylamine-O-sulfonic acid (HOSA) h

100 thesis of commercial reagent (known as Baran aminating reagent precursor) from isobutyric acid and N-

101 A hydroxylamine-derived electrophilic aminating reagent produces a transient and bulky aminium

102 This copper can react with an electrophilic aminating reagent, 1,2-benzisoxazole, to provide enantio

103 onditions with O-pivaloylhydroxylamine as an aminating reagent.

104 cial availability and bench stability of the aminating reagent; the low catalyst loading; and the con

105 aryl/alkenylboronic esters and electrophilic aminating reagents is reported.

106 They were mild electrophilic aminating reagents that reacted at room temperature with

107 h as carbonyl compounds, cyanating reagents, aminating reagents, halogenating reagents, oxygenating r

108 stic insights gained led to the discovery of aminating reagents-nitrite (NO(2)(-)), nitric oxide (NO)

109 ive, readily available, and nitro group-free aminating reagents.

110 es, Carmine were quantitatively extracted by aminated silicas at pH 1-2 and 5-8.

111 were effectively retained by the surface of aminated silicas.

112 y, the dissolved lignin is depolymerized and aminated simultaneously to co-produce monophenolics and

113 A nitrene is likely the aminating species responsible for the observed insertion

114 ng cyanamidyl/arylcyanamidyl radicals as the aminating species.

115 act on two different carbon atoms of its C4-aminated substrate, allowing its deamination and ultimat

116 de following a bottom-up approach through an aminated surface obtained by electrochemical patterning

117 th patterned NH(3)(+)/COO(-) substrates, and aminated surfaces with solution-borne anionic species, c

118 acterial cytochrome P450, that is capable of aminating tertiary C-H bonds to provide chiral alpha-ter

119 a complementary reaction, which reductively aminates the C-C sigma-bond of carbonyls, not the carbon

120 omotes BCAA production in leukaemia cells by aminating the branched-chain keto acids.

121 drolysis of 6 gave 11, which was reductively aminated to give (+/-)-narwedine 2.

122 Glucose isomerase was chemically aminated to increase its reactive surface groups for fav

123 oxidized to mono- and dicarboxylic acids, or aminated to mono- and diamines by using homogeneous and

124 he sensor surface was silanized and directly aminated with (3-aminopropyl) triethoxysilane to create

125 ion characteristics of N-glycans reductively aminated with 2-aminobenzoic acid and 2-aminobenzamide w

126 lting oligosaccharides were then reductively aminated with 2-aminopyridine and the structures identif

127 by treatment with N-glycanase F, reductively aminated with anthranilic acid, and fractionated by norm

128 ea) was immobilized on the Au/SPE previously aminated with cysteamine (Cys) by self-assembling monola

129 The vinyl groups of 1,2-polybutadiene were aminated with ease, and unexpectedly the hydroaminoalkyl

130 Primary alcohols were aminated with high conversion (up to 99%).

131 A broad scope of substrates can be aminated with this method since many functional groups a